Search

This study examines whether youth's goals for their future societal engagement affect their future political activities. We hypothesized, first, that youth's political interest would be a central predictor of their future political activities and, second, that their goals for future societal engagement would moderate their political interest. The greatest future political activity would be among youth who were both politically interested and had set high goals. A community sample of about 400 16-year-olds (M[subscript age]=16.62, SD=0.71, 50.8% females) was followed over four years. The theory of planned behavior was applied. Different types of political action were predicted: offline political activities, online political activities, membership of a political/civic organization, and taking a stance in public for a party pre and post voting in a national election. Age-16 political interest significantly predicted all age-20 political activities, except for being a member of political/civic organizations and actual voting. In line with the second hypothesis, significant interactions were found between political interest and setting societal goals for all the future political activities except voting. It was concluded that youth's early-developed agency in setting goals for their societal engagement has widespread predictive utility for their political activities over a lengthy period.

This study examines the idea that youth's perceptions of their political interactions with important others are influenced by their own political interest to a greater extent than the perceived political interactions that influence youth's political interest. Hence, it was proposed that youth's perceptions of important others' (parents', teachers', friends') political views, political interest, political influence, and support, as well as of being susceptible to others' political communication, are all affected by their own political interest. Community samples of 908 13-year-olds and 869 16-year-olds were followed over 1 year. Latent change models supported the idea that youth's political interest significantly affected their perceptions of important others' political views, influence, and support over time in both cohorts. In 11 out of 12 longitudinal analyses, youth's political interest strongly affected perceptions of their political interactions with others, but none of the 12 analyses showed that the perceptions of political interactions with others strongly predicted a change in youth's political interest. These results suggest that the political interest of young people is an input in their political development, making politically interested youth active agents in their political interactions with their important others.

Coaching literature assumes that people undergo personal change through coaching. We contend that different types of change may occur with coaching and investigate whether this is the case in reflection (a key competence in coaching). Results from our sample of 61 coachees indicate that three types of change (alpha, beta, gamma) are observed across participants. Alpha change refers to a substantive change in reflection (i.e. an increase or decrease), beta to a recalibration of one's assessment of reflection and gamma to a re-conceptualization of reflection. We further examine implicit person theory (IPT) as a predictor and perceived coaching utility as a correlate of the three types of change. We observe a higher probability that incremental IPT will associate with alpha change versus other types of change, and that beta and gamma changes correlate positively and negatively, respectively, with perceived utility for work. No significant correlations are observed between types of change and perceived utility for personal development. Our study represents an exploratory contribution to a better understanding of the within-person changes in reflection following coaching intervention, and has implications for both theory and practice, which we discuss along with indications for future directions.

Barth syndrome (BTHS) is a lethal rare genetic disorder, which results in cardiac dysfunction, severe skeletal muscle weakness, immune issues and growth delay. Mutations in the TAFAZZIN gene, which is responsible for the remodeling of the phospholipid cardiolipin (CL), lead to abnormalities in mitochondrial membrane, including alteration of mature CL acyl composition and the presence of monolysocardiolipin (MLCL). The dramatic increase in the MLCL/CL ratio is the hallmark of patients with BTHS, which is associated with mitochondrial bioenergetics dysfunction and altered membrane ultrastructure. There are currently no specific therapies for BTHS. Here, we showed that cardiac mitochondria isolated from TAFAZZIN knockdown (TazKD) mice presented abnormal ultrastructural membrane morphology, accumulation of vacuoles, pro-fission conditions and defective mitophagy. Interestingly, we found that in vivo treatment of TazKD mice with a CL-targeted small peptide (named SS-31) was able to restore mitochondrial morphology in tafazzin-deficient heart by affecting specific proteins involved in dynamic process and mitophagy. This agrees with our previous data showing an improvement in mitochondrial respiratory efficiency associated with increased supercomplex organization in TazKD mice under the same pharmacological treatment. Taken together our findings confirm the beneficial effect of SS-31 in the amelioration of tafazzin-deficient dysfunctional mitochondria in a BTHS animal model. [ABSTRACT FROM AUTHOR]

Over the recent decades, organizations have had to face a number of major external shocks and crises. Acquiring a better understanding of how human resources are managed under such critical conditions constitutes the main purpose of this study. We conducted a study triangulating different sources (employees, HR managers, and secondary data) and types of data (quantitative and qualitative) to explore how employees in Portuguese organizations perceived the HR practices' implementation during the years of the financial crisis (2011–2014) and how HR managers explained it. Longitudinal evidence from 53 organizations attests to perceived decreasing trends, particularly in training and development and performance management. HR managers legitimize these trends, embracing conventions and revealing the impact of coercive and normative pressures. Our findings highlight the need for renewed attention to be paid to the contextual pressures on HR managers' decision‐making and actions that could severely endanger their role as strategic partners and their embrace of sustainable HRM. [ABSTRACT FROM AUTHOR]

The amount of Insulin Growth Factor 2 (IGF2) controls the rate of embryonal and postnatal growth. The IGF2 and adjacent H19 are the imprinted genes of the telomeric cluster in the 11p15 chromosomal region regulated by differentially methylated regions (DMRs) or imprinting centers (ICs): H19/IGF2:IG-DMR (IC1). Dysregulation due to IC1 Loss-of-Methylation (LoM) or Gain-of-Methyaltion (GoM) causes Silver-Russell syndrome (SRS) or Beckwith-Wiedemann syndrome (BWS) disorders associated with growth retardation or overgrowth, respectively. Specific features define each of the two syndromes, but isolated asymmetry is a common cardinal feature, which is considered sufficient for a diagnosis in the BWS spectrum. Here, we report the case of a girl with right body asymmetry, which suggested BWS spectrum. Later, BWS/SRS molecular analysis identified IC1_LoM revealing the discrepant diagnosis of SRS. A clinical re-evaluation identified a relative macrocephaly and previously unidentified growth rate at lower limits of normal at birth, feeding difficulties, and asymmetry. Interestingly, and never previously described in IC1_LoMSRS patients, since the age of 16, she has developed hand-writer's cramps, depression, and bipolar disorder. Trio-WES identified a VPS16 heterozygous variant [NM_022575.4:c.2185C>G:p.Leu729Val] inherited from her healthy mother. VPS16 is involved in the endolysosomal system, and its dysregulation is linked to autosomal dominant dystonia with incomplete penetrance and variable expressivity. IGF2 involvement in the lysosomal pathway led us to speculate that the neurological phenotype of the proband might be triggered by the concurrent IGF2 deficit and VPS16 alteration. [ABSTRACT FROM AUTHOR]

Research on supervisory feedback has burgeoned over the past 20 years. We ask, what does it have to offer to management practitioners, and is this knowledge conveyed in a constructive way? To answer these questions, we conducted a systematic literature review of the practical implications contained in feedback studies. Based on our retained articles (N = 120) and using the W‐H questions as our guiding framework, we critically discuss: Why recommendations are offered, What recommendations are endorsed, When and Where the recommendations are presented as most applicable, to Whom those are addressed, and How they are framed by researchers. In so doing, we summarise the indications that scientific research has offered to practitioners; moreover, following the same framework and the insights collected via a follow‐up survey of academics (N = 61), we provide recommendations to researchers across the management and psychology disciplines on how to craft their practical implications sections in a way that may help bridge the gap between research and practice. [ABSTRACT FROM AUTHOR]

This longitudinal study examines the role that students' political reputation in class plays in their future political activities offline together with other people. When aged 16, students were asked to nominate the classmates they considered politically knowledgeable and verbal in class, that is, as having a political reputation. This measure of political reputation was used to predict the participants' political activities offline four years later at age 20 and their attempts to take a stand in public in the national election the same year. The study controlled for individual differences in political interest, self‐perceived political impact in class, the students' political activities at age 16, and also gender and immigrant status. About 300 Swedish students were followed up four years later. Political reputation in class positively predicted future political activities offline, membership of political organizations, and attempts to take a stand in public for a party in the forthcoming national election. At the same time, the role played by political reputation depended upon students' other characteristics, especially their levels of anger and popularity, as observed by classmates. Evidently, the group dynamics in class that give some students a political reputation have long‐term consequences for their future political activities. [ABSTRACT FROM AUTHOR]

This study examines whether youth's goals for their future societal engagement affect their future political activities. We hypothesized, first, that youth's political interest would be a central predictor of their future political activities and, second, that their goals for future societal engagement would moderate their political interest. The greatest future political activity would be among youth who were both politically interested and had set high goals. A community sample of about 400 16-year-olds (Mage =16.62, SD =0.71, 50.8% females) was followed over four years. The theory of planned behavior was applied. Different types of political action were predicted: offline political activities, online political activities, membership of a political/civic organization, and taking a stance in public for a party pre and post voting in a national election. Age-16 political interest significantly predicted all age-20 political activities, except for being a member of political/civic organizations and actual voting. In line with the second hypothesis, significant interactions were found between political interest and setting societal goals for all the future political activities except voting. It was concluded that youth's early-developed agency in setting goals for their societal engagement has widespread predictive utility for their political activities over a lengthy period. [ABSTRACT FROM AUTHOR]