Search

Your search keyword '"Rubino, Salvatore"' showing total 25 results
Start Over Author "Rubino, Salvatore" Publication Year Range Last 3 years
25 results on '"Rubino, Salvatore"'

1. Ancient Plasmodium genomes shed light on the history of human malaria

Author

Michel, Megan, Skourtanioti, Eirini, Pierini, Federica, Guevara, Evelyn K., Mötsch, Angela, Kocher, Arthur, Barquera, Rodrigo, Bianco, Raffaela A., Carlhoff, Selina, Coppola Bove, Lorenza, Freilich, Suzanne, Giffin, Karen, Hermes, Taylor, Hiß, Alina, Knolle, Florian, Nelson, Elizabeth A., Neumann, Gunnar U., Papac, Luka, Penske, Sandra, Rohrlach, Adam B., Salem, Nada, Semerau, Lena, Villalba-Mouco, Vanessa, Abadie, Isabelle, Aldenderfer, Mark, Beckett, Jessica F., Brown, Matthew, Campus, Franco G. R., Chenghwa, Tsang, Cruz Berrocal, María, Damašek, Ladislav, Duffett Carlson, Kellie Sara, Durand, Raphaël, Ernée, Michal, Fântăneanu, Cristinel, Frenzel, Hannah, García Atiénzar, Gabriel, Guillén, Sonia, Hsieh, Ellen, Karwowski, Maciej, Kelvin, David, Kelvin, Nikki, Khokhlov, Alexander, Kinaston, Rebecca L., Korolev, Arkadii, Krettek, Kim-Louise, Küßner, Mario, Lai, Luca, Look, Cory, Majander, Kerttu, Mandl, Kirsten, Mazzarello, Vittorio, McCormick, Michael, de Miguel Ibáñez, Patxuka, Murphy, Reg, Németh, Rita E., Nordqvist, Kerkko, Novotny, Friederike, Obenaus, Martin, Olmo-Enciso, Lauro, Onkamo, Päivi, Orschiedt, Jörg, Patrushev, Valerii, Peltola, Sanni, Romero, Alejandro, Rubino, Salvatore, Sajantila, Antti, Salazar-García, Domingo C., Serrano, Elena, Shaydullaev, Shapulat, Sias, Emanuela, Šlaus, Mario, Stančo, Ladislav, Swanston, Treena, Teschler-Nicola, Maria, Valentin, Frederique, Van de Vijver, Katrien, Varney, Tamara L., Vigil-Escalera Guirado, Alfonso, Waters, Christopher K., Weiss-Krejci, Estella, Winter, Eduard, Lamnidis, Thiseas C., Prüfer, Kay, Nägele, Kathrin, Spyrou, Maria, Schiffels, Stephan, Stockhammer, Philipp W., Haak, Wolfgang, Posth, Cosimo, Warinner, Christina, Bos, Kirsten I., Herbig, Alexander, and Krause, Johannes

Published
2024
Full Text
View/download PDF

4. Enterobacterales carrying chromosomal AmpC β-lactamases in Europe (EuESCPM): Epidemiology and antimicrobial resistance burden from a cohort of 27 hospitals, 2020–2022

Author

Boattini, Matteo, Bianco, Gabriele, Llorente, Laura Iglesias, Acero, Laura Alonso, Nunes, Daniel, Seruca, Miguel, Mendes, Vasco Santos, Almeida, André, Bastos, Paulo, Rodríguez-Villodres, Ángel, Gascón, Adelina Gimeno, Halperin, Ana Verónica, Cantón, Rafael, Escartín, Maria Nieves Larrosa, González-López, Juan José, Floch, Pauline, Massip, Clémence, Chainier, Delphine, Barraud, Olivier, Dortet, Laurent, Cuzon, Gaëlle, Zancanaro, Clément, Mizrahi, Assaf, Schade, Rogier, Rasmussen, Asger Nellemann, Schønning, Kristian, Hamprecht, Axel, Schaffarczyk, Lukas, Glöckner, Stefan, Rödel, Jürgen, Kristóf, Katalin, Balonyi, Ágnes, Mancini, Stefano, Quiblier, Chantal, Fasciana, Teresa, Giammanco, Anna, Paglietti, Bianca, Rubino, Salvatore, Budimir, Ana, Bedenić, Branka, Rubic, Zana, Marinović, Jelena, Gartzonika, Konstantina, Christaki, Eirini, Mavromanolaki, Viktoria Eirini, Maraki, Sofia, Yalçın, Tuğba Yanık, Azap, Özlem Kurt, Licker, Monica, Musuroi, Corina, Talapan, Daniela, Vrancianu, Corneliu Ovidiu, Comini, Sara, Zalas-Więcek, Patrycja, Michalska, Anna, Cavallo, Rossana, Melo Cristino, José, and Costa, Cristina

Published
2024
Full Text
View/download PDF

7. Multifactorial action of lavender and lavandin oils against filamentous fungi

Author

Donadu, Matthew Gavino, primary, Ferrari, Marco, additional, Behzadi, Payam, additional, Trong Le, Nhan, additional, Usai, Donatella, additional, Fiamma, Maura, additional, Battah, Basem, additional, Barac, Aleksandra, additional, Bellardi, Maria Grazia, additional, Hoai, Thi Nguyen, additional, Mazzarello, Vittorio, additional, Rubino, Salvatore, additional, Cappuccinelli, Piero, additional, and Zanetti, Stefania, additional

Published
2024
Full Text
View/download PDF

8. Ancient Plasmodiumgenomes shed light on the history of human malaria

Author

Michel, Megan, Skourtanioti, Eirini, Pierini, Federica, Guevara, Evelyn K., Mötsch, Angela, Kocher, Arthur, Barquera, Rodrigo, Bianco, Raffaela A., Carlhoff, Selina, Coppola Bove, Lorenza, Freilich, Suzanne, Giffin, Karen, Hermes, Taylor, Hiß, Alina, Knolle, Florian, Nelson, Elizabeth A., Neumann, Gunnar U., Papac, Luka, Penske, Sandra, Rohrlach, Adam B., Salem, Nada, Semerau, Lena, Villalba-Mouco, Vanessa, Abadie, Isabelle, Aldenderfer, Mark, Beckett, Jessica F., Brown, Matthew, Campus, Franco G. R., Chenghwa, Tsang, Cruz Berrocal, María, Damašek, Ladislav, Duffett Carlson, Kellie Sara, Durand, Raphaël, Ernée, Michal, Fântăneanu, Cristinel, Frenzel, Hannah, García Atiénzar, Gabriel, Guillén, Sonia, Hsieh, Ellen, Karwowski, Maciej, Kelvin, David, Kelvin, Nikki, Khokhlov, Alexander, Kinaston, Rebecca L., Korolev, Arkadii, Krettek, Kim-Louise, Küßner, Mario, Lai, Luca, Look, Cory, Majander, Kerttu, Mandl, Kirsten, Mazzarello, Vittorio, McCormick, Michael, de Miguel Ibáñez, Patxuka, Murphy, Reg, Németh, Rita E., Nordqvist, Kerkko, Novotny, Friederike, Obenaus, Martin, Olmo-Enciso, Lauro, Onkamo, Päivi, Orschiedt, Jörg, Patrushev, Valerii, Peltola, Sanni, Romero, Alejandro, Rubino, Salvatore, Sajantila, Antti, Salazar-García, Domingo C., Serrano, Elena, Shaydullaev, Shapulat, Sias, Emanuela, Šlaus, Mario, Stančo, Ladislav, Swanston, Treena, Teschler-Nicola, Maria, Valentin, Frederique, Van de Vijver, Katrien, Varney, Tamara L., Vigil-Escalera Guirado, Alfonso, Waters, Christopher K., Weiss-Krejci, Estella, Winter, Eduard, Lamnidis, Thiseas C., Prüfer, Kay, Nägele, Kathrin, Spyrou, Maria, Schiffels, Stephan, Stockhammer, Philipp W., Haak, Wolfgang, Posth, Cosimo, Warinner, Christina, Bos, Kirsten I., Herbig, Alexander, and Krause, Johannes

Abstract

Malaria-causing protozoa of the genus Plasmodiumhave exerted one of the strongest selective pressures on the human genome, and resistance alleles provide biomolecular footprints that outline the historical reach of these species1. Nevertheless, debate persists over when and how malaria parasites emerged as human pathogens and spread around the globe1,2. To address these questions, we generated high-coverage ancient mitochondrial and nuclear genome-wide data from P. falciparum, P. vivaxand P. malariaefrom 16 countries spanning around 5,500 years of human history. We identified P. vivaxand P. falciparumacross geographically disparate regions of Eurasia from as early as the fourth and first millennia bce, respectively; for P. vivax, this evidence pre-dates textual references by several millennia3. Genomic analysis supports distinct disease histories for P. falciparumand P. vivaxin the Americas: similarities between now-eliminated European and peri-contact South American strains indicate that European colonizers were the source of American P. vivax, whereas the trans-Atlantic slave trade probably introduced P. falciparuminto the Americas. Our data underscore the role of cross-cultural contacts in the dissemination of malaria, laying the biomolecular foundation for future palaeo-epidemiological research into the impact of Plasmodiumparasites on human history. Finally, our unexpected discovery of P. falciparumin the high-altitude Himalayas provides a rare case study in which individual mobility can be inferred from infection status, adding to our knowledge of cross-cultural connectivity in the region nearly three millennia ago.

Published
2024
Full Text
View/download PDF

9. An outbreak of COVID-19 after a pilgrimage to Medjugorje due to Delta sublineages.

Author

Lo Presti, Alessandra, Rubino, Salvatore, Ibba, Gabriele, Ambrosio, Luigina, Di Martino, Angela, Ferraro, Federica, Rapiti, Alessia, Maraglino, Francesco, Frisicale, Emanuela Maria, Rezza, Giovanni, Angioj, Flavia, Uzzau, Sergio, Contini, Maria Luciana, Manca, Stefania, Coghe, Ferdinando, Orrù, Germano, Palamara, Anna Teresa, and Stefanelli, Paola

Subjects
*SARS-CoV-2 Delta variant, *COVID-19 pandemic, *WHOLE genome sequencing, *COUNTRY of origin (Immigrants), *PILGRIMS & pilgrimages
Abstract

Introduction: A COVID-19 outbreak occurred at the end of October 2021 among pilgrims returning from Medjugorje (Bosnia and Herzegovina). Methodology: Whole genome sequencing (WGS) of SARS-CoV-2, epidemiological data, and phylogenetic analysis were used to reconstruct outbreak dynamics. Results: The results suggest that only in one case, associated with the SARS-CoV-2 sub-lineage AY.9.2, it is possible to trace back the place of contagion to Medjugorje, while the other cases were likely to be acquired in the country of origin. Conclusions: The combined use of phylogenetic data derived from WGS, and epidemiological data allowed us to study epidemic dynamics and to formulate a possible hypothesis on the place of exposure to SARS-CoV-2. The identification of different sub-lineages of the SARSCoV-2 Delta variant also suggested that different chains of transmission contributed to the outbreak. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

13. High-risk lineages among extended-spectrum β-lactamase-producing Escherichia coli from extraintestinal infections in Maputo Central Hospital, Mozambique

Author

Santona, Antonella, primary, Sumbana, José João, additional, Fiamma, Maura, additional, Deligios, Massimo, additional, Taviani, Elisa, additional, Simbine, Samuel Elija, additional, Zimba, Tomas, additional, Sacarlal, Jahit, additional, Rubino, Salvatore, additional, and Paglietti, Bianca, additional

Published
2022
Full Text
View/download PDF

17. Alpha, Beta, Delta, Omicron, and SARS-CoV-2 Breakthrough Cases: Defining Immunological Mechanisms for Vaccine Waning and Vaccine-Variant Mismatch

Author

Hewins, Benjamin, primary, Rahman, Motiur, additional, Bermejo-Martin, Jesus F., additional, Kelvin, Alyson A., additional, Richardson, Christopher D., additional, Rubino, Salvatore, additional, Kumar, Anuj, additional, Ndishimye, Pacifique, additional, Toloue Ostadgavahi, Ali, additional, Mahmud-Al-Rafat, Abdullah, additional, and Kelvin, David J., additional

Published
2022
Full Text
View/download PDF

18. Occult Vancomycin-Resistant Enterococcus faecium ST117 Displaying a Highly Mutated vanB 2 Operon.

Author

Santona, Antonella, Taviani, Elisa, Fiamma, Maura, Deligios, Massimo, Hoang, Hoa M., Sanna, Silvana, Rubino, Salvatore, and Paglietti, Bianca

Subjects
ENTEROCOCCUS, ENTEROCOCCUS faecium, ENTEROCOCCAL infections, MISSENSE mutation, OCCULTISM, VANCOMYCIN resistance, GENOTYPES
Abstract

Rare information is available on clinical Enterococcus faecium encountered in Sardinia, Italy. This study investigated the antimicrobial susceptibility profiles and genotypic characteristics of E. faecium isolated at the University Hospital of Sassari, Italy, using the Vitek2 system and PCR, MLST, or WGS. Vitek2 revealed two VanB-type vancomycin-resistant Enterococcus faecium (VREfm) isolates (MICs mg/L = 8 and ≥32) but failed to detect vancomycin resistance in one isolate (MIC mg/L ≤ 1) despite positive genotypic confirmation of vanB gene, which proved to be vancomycin resistant by additional phenotypic methods (MICs mg/L = 8). This vanB isolate was able to increase its vancomycin MIC after exposure to vancomycin, unlike the "classic" occult vanB-carrying E. faecium, becoming detectable by Vitek 2 (MICs mg/L ≥ 32). All three E. faecium had highly mutated vanB2 operons, as part of a chromosomally integrated Tn1549 transposon, with common missense mutations in VanH and VanB2 resistance proteins and specific missense mutations in the VanW accessory protein. There were additional missense mutations in VanS, VanH, and VanB proteins in the vanB2-carrying VREfm isolates compared to Vitek2. The molecular typing revealed a polyclonal hospital-associated E. faecium population from Clade A1, and that vanB2-VREfm, and nearly half of vancomycin-susceptible E. faecium (VSEfm) analyzed, belonged to ST117. Based on core genome-MLST, ST117 strains had different clonal types (CT), excluding nosocomial transmission of specific CT. Detecting vanB2-carrying VREfm isolates by Vitek2 may be problematic, and alternative methods are needed to prevent therapeutic failure and spread. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

20. Phylogeography and genomic epidemiology of SARS-CoV-2 in Italy and Europe with newly characterized Italian genomes between February-June 2020

Author

Lai, Alessia, Bergna, Annalisa, Toppo, Stefano, Morganti, Marina, Menzo, Stefano, Ghisetti, Valeria, Bruzzone, Bianca, Codeluppi, Mauro, Fiore, Vito, Rullo, Emmanuele Venanzi, Antonelli, Guido, Sarmati, Loredana, Brindicci, Gaetano, Callegaro, Annapaola, Sagnelli, Caterina, Francisci, Daniela, Vicenti, Ilaria, Miola, Arianna, Tonon, Giovanni, Cirillo, Daniela, Menozzi, Ilaria, Caucci, Sara, Cerutti, Francesco, Orsi, Andrea, Schiavo, Roberta, Babudieri, Sergio, Nunnari, Giuseppe, Mastroianni, Claudio M., Andreoni, Massimo, Monno, Laura, Guarneri, Davide, Coppola, Nicola, Crisanti, Andrea, Galli, Massimo, Zehender, Gianguglielmo, Balotta, Claudia, Ventura, Carla della, Schiuma, Marco, Lavezzo, Enrico, Fontana, Paolo, Bianco, Luca, Bertolotti, Luigi, Manuto, Laura, Grazioli, Marco, Bianca, Federico, Del Vecchio, Claudia, Franchin, Elisa, Onelia, Francesco, Spitaleri, Andrea, Saluzzo, Francesca, Lorenzin, Giovanni, Pongolini, Stefano, Scaltriti, Erika, Soliani, Laura, Bagnarelli, Patrizia, Turchi, Chiara, Onofri, Valerio, Melchionda, Filomena, Tagliabracci, Adriano, Burdino, Elisa, Milia, Maria Grazia, Caligiuri, Patrizia, De Pace, Vanessa, Ricucci, Valentina, Domnich, Alexander, Boccotti, Simona, Cristina, Leoni Maria, Cascio, Giuliana Lo, Rubino, Salvatore, Lai, Vincenzo, Rocca, Giulia, Govoni, Rosalba, Mancuso, Giuseppe, Campagna, Roberta, Mazzuti, Laura, Oliveto, Giuseppe, Turriziani, Ombretta, Campogiani, Laura, Compagno, Mirko, Coppola, Luigi, Crea, Angela Maria Antonia, De Simone, Giuseppe, Di Lorenzo, Andrea, Ferrari, Ludovica, Iannetta, Marco, Malagnino, Vincenzo, Mulas, Tiziana, Rossi, Benedetta, Spalliera, Ilaria, Tedde, Simona, Teti, Elisabetta, Vitale, Pietro, Zordan, Marta, Milano, Eugenio, Lagioia, Antonella, Gallitelli, Rosa, Starace, Mario, Minichini, Carmine, Di Fraia, Alessia, Schioppa, Maddalena, Greco, Rita, Gidari, Anna, Zazzi, Maurizio, Dragoni, Filippo, Puma, Laura Li, Ronchiadin, Silvia, Ruggerone, Luigi, Russignaga, Dario, Lai, Alessia, Bergna, Annalisa, Toppo, Stefano, Morganti, Marina, Menzo, Stefano, Ghisetti, Valeria, Bruzzone, Bianca, Codeluppi, Mauro, Fiore, Vito, Rullo, Emmanuele Venanzi, Antonelli, Guido, Sarmati, Loredana, Brindicci, Gaetano, Callegaro, Annapaola, Sagnelli, Caterina, Francisci, Daniela, Vicenti, Ilaria, Miola, Arianna, Tonon, Giovanni, Cirillo, Daniela, Menozzi, Ilaria, Caucci, Sara, Cerutti, Francesco, Orsi, Andrea, Schiavo, Roberta, Babudieri, Sergio, Nunnari, Giuseppe, Mastroianni, Claudio M, Andreoni, Massimo, Monno, Laura, Guarneri, Davide, Coppola, Nicola, Crisanti, Andrea, Galli, Massimo, and Zehender, Gianguglielmo

Subjects
Europe, Phylogeography, Genome, Italy, SARS-CoV-2, Communicable Disease Control, Humans, COVID-19, Genome, Viral, Viral, Settore MED/17, Human
Abstract

The aims of this study were to characterize new SARS-CoV-2 genomes sampled all over Italy and to reconstruct the origin and the evolutionary dynamics in Italy and Europe between February and June 2020. The cluster analysis showed only small clusters including < 80 Italian isolates, while most of the Italian strains were intermixed in the whole tree. Pure Italian clusters were observed mainly after the lockdown and distancing measures were adopted. Lineage B and B.1 spread between late January and early February 2020, from China to Veneto and Lombardy, respectively. Lineage B.1.1 (20B) most probably evolved within Italy and spread from central to south Italian regions, and to European countries. The lineage B.1.1.1 (20D) developed most probably in other European countries entering Italy only in the second half of March and remained localized in Piedmont until June 2020. In conclusion, within the limitations of phylogeographical reconstruction, the estimated ancestral scenario suggests an important role of China and Italy in the widespread diffusion of the D614G variant in Europe in the early phase of the pandemic and more dispersed exchanges involving several European countries from the second half of March 2020.

Published
2022

21. Emerging Clinical Features of COVID-19 Related Pancreatitis: Case Reports and Review of the Literature

Author

Fiore, Vito, primary, Beretta, Rosalba, additional, De Vito, Andrea, additional, Barac, Aleksandra, additional, Maida, Ivana, additional, Joeseph Kelvin, David David, additional, Piu, Claudia, additional, Lai, Vincenzo, additional, Madeddu, Giordano, additional, Rubino, Salvatore, additional, Stevanovic, Goran, additional, Korica, Stefan, additional, and Babudieri, Sergio, additional

Published
2022
Full Text
View/download PDF

24. “Swab Team” in the SARS-CoV-2 outbreak containment among healthcare workers

Author

Bussu, Francesco, primary, Rizzo, Davide, additional, Saderi, Laura, additional, Piras, Antonio, additional, De Luca, Laura Maria, additional, De Riu, Giacomo, additional, Vaira, Luigi Angelo, additional, Serra, Antonello, additional, Altrudo, Paola, additional, Delogu, Domenico, additional, Dettori, Ignazio, additional, Riu, Francesco Giuseppe, additional, Angioj, Flavia, additional, Firino, Laura, additional, Govoni, Rosalba, additional, Ibba, Gabriele, additional, Lai, Vincenzo, additional, Mura, Erica, additional, Paglietti, Bianca, additional, Piu, Claudia, additional, Puggioni, Anna, additional, Rimini, Elena, additional, Rocca, Giulia, additional, Serra, Caterina, additional, Uzzau, Sergio, additional, Rubino, Salvatore, additional, and Sotgiu, Giovanni, additional

Published
2021
Full Text
View/download PDF

25. Polyclonal emergence of MDR Enterobacter cloacaecomplex isolates producing multiple extended spectrum beta-lactamases at Maputo Central Hospital, Mozambique

Author

Sumbana, José, Santona, Antonella, Fiamma, Maura, Taviani, Elisa, Deligios, Massimo, Chongo, Ventura, Sacarlal, Jahit, Rubino, Salvatore, and Paglietti, Bianca

Abstract

Enterobacterspp. are important nosocomial pathogens responsible of a wide variety of infections, mainly due to Extended Spectrum β-Lactamase (ESBL) producing isolates, constituting a global public health issue in terms of clinical treatment and infection control, especially in low-income countries, where last-line treatment is often unavailable and there is weak nosocomial surveillance. In this study, we conducted a phenotypic and molecular characterization of 8 clinical Enterobacterspp. strains, isolated from patient’s blood in three hospitals in Mozambique. Isolates were identified by MALDI-TOF and antimicrobial Susceptibility Testing was performed by VITEK 2 system. Half of isolates were analyzed by PCR for β-lactamases genes, other isolates by Whole Genome Sequencing. We identified all isolates as Enterobacter cloacaecomplex (ECC), those from Maputo Central Hospital were polyclonal, multidrug resistant (5/8), and ESBL producers (50%), carrying blaCTX-M-15and different assortment of blaSHV-12, blaTEM-1Band blaOXA-1, and AmpCs blaCMH-3, blaACT-7and blaACT-9genes. Resistance determinants linked to fluoroquinolone (aac(6')Ib-crand qnrB1) and others antimicrobials were also found. Notably, one isolate showed phenotypically resistance to colistin, while another colistin susceptible isolate carried a silent mcr-9gene. ECC nosocomial surveillance is urgently needed to contain and prevent the dissemination of ESBLs producing clones, and mcr-9spread to other Enterobacteriaceae.

Published
2022
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results