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163 results on '"Rodríguez, Victoria"'

3. The magnitude and variability of neurocognitive performance in first-episode psychosis: a systematic review and meta-analysis of longitudinal studies

Author

Catalan, Ana, McCutcheon, Robert A., Aymerich, Claudia, Pedruzo, Borja, Radua, Joaquim, Rodríguez, Victoria, Salazar de Pablo, Gonzalo, Pacho, Malein, Pérez, Jose Luis, Solmi, Marco, McGuire, Philip, Giuliano, Anthony J., Stone, William S., Murray, Robin M., Gonzalez-Torres, Miguel Angel, and Fusar-Poli, Paolo

Published
2024
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4. Europe

Author

Rodriguez, Victoria

Published
2024

5. DNA methylation networks underlying mammalian traits.

Author

Haghani, Amin, Li, Caesar, Robeck, Todd, Zhang, Joshua, Lu, Ake, Ablaeva, Julia, Acosta-Rodríguez, Victoria, Adams, Danielle, Alagaili, Abdulaziz, Almunia, Javier, Aloysius, Ajoy, Amor, Nabil, Ardehali, Reza, Arneson, Adriana, Baker, C, Banks, Gareth, Belov, Katherine, Bennett, Nigel, Black, Peter, Blumstein, Daniel, Bors, Eleanor, Breeze, Charles, Brooke, Robert, Brown, Janine, Carter, Gerald, Caulton, Alex, Cavin, Julie, Chakrabarti, Lisa, Chatzistamou, Ioulia, Chavez, Andreas, Chen, Hao, Cheng, Kaiyang, Chiavellini, Priscila, Choi, Oi-Wa, Clarke, Shannon, Cook, Joseph, Cooper, Lisa, Cossette, Marie-Laurence, Day, Joanna, DeYoung, Joseph, Dirocco, Stacy, Dold, Christopher, Dunnum, Jonathan, Ehmke, Erin, Emmons, Candice, Emmrich, Stephan, Erbay, Ebru, Erlacher-Reid, Claire, Faulkes, Chris, Fei, Zhe, Ferguson, Steven, Finno, Carrie, Flower, Jennifer, Gaillard, Jean-Michel, Garde, Eva, Gerber, Livia, Gladyshev, Vadim, Goya, Rodolfo, Grant, Matthew, Green, Carla, Hanson, M, Hart, Daniel, Haulena, Martin, Herrick, Kelsey, Hogan, Andrew, Hogg, Carolyn, Hore, Timothy, Huang, Taosheng, Izpisua Belmonte, Juan, Jasinska, Anna, Jones, Gareth, Jourdain, Eve, Kashpur, Olga, Katcher, Harold, Katsumata, Etsuko, Kaza, Vimala, Kiaris, Hippokratis, Kobor, Michael, Kordowitzki, Pawel, Koski, William, Krützen, Michael, Kwon, Soo, Larison, Brenda, Lee, Sang-Goo, Lehmann, Marianne, Lemaître, Jean-François, Levine, Andrew, Li, Xinmin, Li, Cun, Lim, Andrea, Lin, David, Lindemann, Dana, Liphardt, Schuyler, Little, Thomas, Macoretta, Nicholas, Maddox, Dewey, Matkin, Craig, Mattison, Julie, McClure, Matthew, and Mergl, June

Subjects
Adult, Animals, Humans, DNA Methylation, Epigenesis, Genetic, Epigenome, Genome, Mammals, Phylogeny
Abstract

Using DNA methylation profiles (n = 15,456) from 348 mammalian species, we constructed phyloepigenetic trees that bear marked similarities to traditional phylogenetic ones. Using unsupervised clustering across all samples, we identified 55 distinct cytosine modules, of which 30 are related to traits such as maximum life span, adult weight, age, sex, and human mortality risk. Maximum life span is associated with methylation levels in HOXL subclass homeobox genes and developmental processes and is potentially regulated by pluripotency transcription factors. The methylation state of some modules responds to perturbations such as caloric restriction, ablation of growth hormone receptors, consumption of high-fat diets, and expression of Yamanaka factors. This study reveals an intertwined evolution of the genome and epigenome that mediates the biological characteristics and traits of different mammalian species.

Published
2023

9. Circadian alignment of early onset caloric restriction promotes longevity in male C57BL/6J mice

Author

Acosta-Rodríguez, Victoria, Rijo-Ferreira, Filipa, Izumo, Mariko, Xu, Pin, Wight-Carter, Mary, Green, Carla B, and Takahashi, Joseph S

Subjects
Biological Psychology, Biomedical and Clinical Sciences, Psychology, Nutrition, Genetics, Aging, 1.1 Normal biological development and functioning, Animals, Caloric Restriction, Circadian Rhythm, Gene Expression Regulation, Longevity, Male, Mice, Mice, Inbred C57BL, General Science & Technology
Abstract

Caloric restriction (CR) prolongs life span, yet the mechanisms by which it does so remain poorly understood. Under CR, mice self-impose chronic cycles of 2-hour feeding and 22-hour fasting, raising the question of if it is calories, fasting, or time of day that is the cause of this increased life span. We show here that 30% CR was sufficient to extend the life span by 10%; however, a daily fasting interval and circadian alignment of feeding acted together to extend life span by 35% in male C57BL/6J mice. These effects were independent of body weight. Aging induced widespread increases in gene expression associated with inflammation and decreases in the expression of genes encoding components of metabolic pathways in liver from ad libitum-fed mice. CR at night ameliorated these aging-related changes. Our results show that circadian interventions promote longevity and provide a perspective to further explore mechanisms of aging.

Published
2022

12. ADAMTS13 recovery in acute thrombotic thrombocytopenic purpura after caplacizumab therapy

Author

Abio Calvete, Mariola, Albert, Albert, Alberto López García, Alberto, Alegre, Adrian, Alkorta Eizagirre, Aitziber, Alonso Escobar, María Nieves, Alonso Madrigal, Cristina, Amunarriz, Cristina, Antelo Caamaño, María Luisa, Arbona Castaño, Cristina, Ballester Ruiz, Maria Carmen, Ballina Martín, Belén, Berberana Fernández de Murias, Margarita, Berrueco Moreno, Ruben, Bueno, Jose Luis, Calderón López, María Teresa, Chica Gullón, Esther, Cid Vidal, Joan, Contreras Barbeta, Enric, Cuéllar Pérez-Ávila, Clara, de la Rubia Comos, Javier, Del Orbe Barreto, Rafael Andres, Del Río Garma, Julio, Díaz Valdés, José R., Diaz-Ricart, Maribel, Diez Gallarreta, Zuriñe, Dueñas Hernando, Virginia, Eguia, Blanca, Escoda, Lourdes, Fernández Docampo, Marta, Fernandez Fuertes, Fernando, Fernández Muñoz, Hermogenes, Fernández Sánchez de Mora, Maria Carmen, Fernandez Zarzoso, Miguel, Fidalgo, Teresa, Flores Ballester, Elena, Fonte Feal, Cristina, Galvez, Francisco Javier, Garcia Arroba Peinado, Jose, García Candel, Faustino, Garcia Erce, Jose Antonio, García Gala, José María, Gimeno, JJ, Gómez, Delia, Gómez Seguí, Inés, Gomez Vazquez, Maria Jesus, Gonzalez, Carlos, González Fernández, Fernando Ataulfo, Gonzalez Porras, Jose Ramon, Gonzalez Rodriguez, Victoria Paz, Goterris Viciedo, Rosa, Guerra Domínguez, Luisa, Guillén García, Helga, Hernandez, Adoracion, Hernández Castellet, José Carlos, Hernandez Mohedo, Francisca, Hernandez Vazquez, Laura, Hidalgo Soto, Marta, Hong Tam, Azueg Hang, Kerguelen Fuentes, Ana Lilia, Leal Bento, Marta, Lopes, Raquel, López, Olga, López Chuliá, Francisca, Maria Jose Busto, Maria Jose, Martín Hernández, María Paz, Martinez Estefano, Elvira, Martinez Nieto, Jorge, Martinez Redondo, Consuelo, Martinez Revuelta, Eva, Medina Marrero, Laura, Mingot Castellano, María Eva, Morales Sanz, María Dolores, Moreno, Gemma, Moreno Beltrán, Mª Esperanza, Moreno Chulilla, Jose Antonio, Nistal Gil, Sara, Oliva Hernandez, Ana Yurena, Pascual, Teresa, Pascual Izquierdo, Crisina, Paumard Rodríguez, Elena, Pecos, Patricia, Peña Marcos, Francisco, Pereira Coelho, Daniela Sofia, Pérez Segura, Gloria Maria, Perez-Lopez, Olga, Prieto Pareja, Elena, Ramiro, Laia, Richart López, Luis Alberto, Rodriguez Dominguez, Maria Jesus, Rodriguez Nuñez, Antonio, Ruiz Sainz, María Elena, Saez Serrano, Isabel, Salinas Argente, Ramón, Sanchez, Maria Elena, Sanchez Anton, Piva, Sánchez Fernández, Mª Soledad, Sebastian, Elena, Simona, Gabriela, Solanich Moreno, Xabier, Soledad Casado, Soledad, Tallón, Jose David, Turcu, Violeta, Valledor Méndez, Manuel, Vidan Y Estevez, Julia, Viejo Llorente, Aurora, Bienert, Álvaro, Serrano, Alfons, Llorente, Laura, Campuzano, Verónica, Tallón, Inmaculada, Pons, Verónica, Linares, Mónica, Valles, Ana, Martínez Francés, Antonio, Freiria, Carmen, González Arias, Elena, Araujo, Enmanuel, Marco de Lucas, Fernando, López, Juan Antonio, Uribe Barrientos, Marisol, Calviño, Michael, Gómez Calafat, Montse, Marco Vera, Pascual, Fariña, Sabela, Zalba, Saioa, Monsalvo, Silvia, Escamilla, Virginia, Mingot-Castellano, María-Eva, García-Candel, Faustino, Martínez-Nieto, Jorge, García-Arroba, José, de la Rubia-Comos, Javier, Gómez-Seguí, Inés, Paciello-Coronel, María-Liz, Valcárcel-Ferreiras, David, Jiménez, Moraima, Cid, Joan, Lozano, Miquel, García-Gala, José-María, Angós-Vazquez, Sonia, Vara-Pampliega, Miriam, Guerra-Domínguez, Luisa, Ávila-Idrobo, Laura-Francisca, Oliva-Hernandez, Ana, Zalba-Marcos, Saioa, Tallón-Ruiz, Inmaculada, Ortega-Sánchez, Sandra, Goterris-Viciedo, Rosa, Moreno-Jiménez, Gemma, Domínguez-Acosta, Lourdes, Araiz-Ramírez, María, Hernández-Mateos, Luis, Flores-Ballesteros, Elena, del Río-Garma, Julio, and Pascual-Izquierdo, Cristina

Published
2024
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14. National observational study about the surgical treatment of anal fistula: Does the kind of hospital modify the results?

Author

Soria, Javier Espinosa, Orejuela, Jordi Seguí, Corral, Natalia Gutiérrez, Agundez, María Carmona, Pérez, David Saavedra, Mejía, Helga Calvaienen, Segura, Marta Barros, Pellino, Gianluca, León, Gerardo Rodríguez, Salido, Andrea Jiménez, Sánchez, Tatiana Gómez, Ortiz, Susana Roldán, Gutiérrez, Luis Eloy Cantero, Pazos, Natalia Suarez, Poch, Lidia Cristóbal, López, Juan Ramón Gómez, Sánchez, Pablo Méndez, Veiga, Pilar Fernández, Rodríguez, Victoria Erene Flores, Valderrama, Oscar Cano, Iribarren, Enrique Moncada, Torrecilla, Nuria Ortega, Acosta, Alberto Carrillo, Illescas, Cristina Plata, Vigil, Jose Luis Diez, Martínez, Estefanía Laviano, Martos, María Beltrán, Zafra, David Ambrona, Farré, Silvia Pérez, Pé rez, David Díaz, Herrera, Ana Belén Gallardo, Viejo, Elena, Jiménez, Juan Ocaña, Núñez, Jordi Núñez, Bonito, Alba Correa, Marcos, Elena Bermejo, Bocanegra, Marta González, Martínez, Alicia Ferrer, Fernández, Irene Mirón, Sánchez-Migallón, Elena González, Solano Palao, María Teresa, Ros, Emilio Peña, Cao, Inés Aldrey, Rodríguez, Carlenny Suero, Maderuelo, Victoria, Amo, Aroa Abascal, Catena, Juan Cintas, La Villa, María del Campo, Ramo, Mahur Esmaili, Benítez, Javier Broeckhuizen, Barles, Ana Navarro, Sánchez, Luis Eduardo Pérez, Sánchez, Ana Soto, Jiménez, Nélida Díaz, González, Ana María Feria, Pina, Estefanía Domenech, Comesaña, Alejandro Ros, Coltell, Zutoia Balciscueta, Santiago, Leticia Pérez, Hernández, Luisa Paola Garzón, de Andrés Gómez, Alejandra, Abellán, Antonio Melero, Muriel, Jorge Sancho, Scheiding, Mónica Millán, Cholewa, Hanna, Iranzo, Marina Alarcón, Pelegri, Ana Fluixá, Miguel, Tamara Fernández, Machón, Natalia Ortega, Hernández, Natalia Alonso, Granero, Álvaro García, Taboada, Tatiana Civeira, Fernández, Yago Rojo, Cuellar, Jose Aurelio Navas, Castillo, Celia, Miguelañez, Isabel Pascual, Barbeitio, Sandra Dios, Díaz, María Luisa Reyes, Cabrera, Ana María García, Solís, Irene María Ramallo, Pérez, Teresa Pérez, Marín, Gabriel, Lillo, Aranzazu Calero, Guillén, Luis Sánchez, Noguera, Julia López, Pérez, Miguel Ángel, Cano-Valderrama, Oscar, Cerdán-Santacruz, Carlos, Fernández Veiga, Pilar, Fernández-Miguel, Tamara, García-Granero, Álvaro, Calderón, Teresa, and Reyes, María L.

Published
2024
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15. Estudio observacional nacional sobre tratamiento quirúrgico de fístula anal: ¿tiene impacto en los resultados el tipo de hospital?

Author

Espinosa Soria, Javier, Seguí Orejuela, Jordi, Corral, Natalia Gutiérrez, Carmona Agundez, María, Saavedra Pérez, David, Calvaienen Mejía, Helga, Barros Segura, Marta, Pellino, Gianluca, Rodríguez León, Gerardo, Jiménez Salido, Andrea, Gómez Sánchez, Tatiana, Roldán Ortiz, Susana, Cantero Gutiérrez, Luis Eloy, Suarez Pazo, Natalia, Cristóbal Poch, Lidia, Gómez López, Juan Ramón, Méndez Sánchez, Pablo, Fernández Veiga, Pilar, Flores Rodríguez, Victoria Erene, Cano Valderrama, Oscar, Moncada Iribarren, Enrique, Ortega Torrecilla, Nuria, Carrillo Acosta, Alberto, Plata Illescas, Cristina, Diez Vigil, Jose Luis, Laviano Martínez, Estefanía, Beltrán Martos, María, Zafra, David Ambrona, Pérez Farré, Silvia, Díaz Pé rez, David, Gallardo Herrera, Ana Belén, Viejo, Elena, Ocaña Jiménez, Juan, Núñez Núñez, Jordi, Correa Bonito, Alba, Bermejo Marcos, Elena, González Bocanegra, Marta, Ferrer Martínez, Alicia, Mirón Fernández, Irene, González Sánchez-Migallón, Elena, Solano Palao, María Teresa, Peña Ros, Emilio, Aldrey Cao, Inés, Suero Rodríguez, Carlenny, Maderuelo, Victoria, Abascal Amo, Aroa, Cintas Catena, Juan, La Villa, María del Campo, Esmaili Ramo, Mahur, Broeckhuizen Benítez, Javier, Navarro Barles, Ana, Pérez Sánchez, Luis Eduardo, Soto Sánchez, Ana, Díaz Jiménez, Nélida, Feria González, Ana María, Domenech Pina, Estefanía, Ros Comesaña, Alejandro, Balciscueta Coltell, Zutoia, Pérez Santiago, Leticia, Garzón Hernández, Luisa Paola, de Andrés Gómez, Alejandra, Melero Abellán, Antonio, Sancho Muriel, Jorge, Millán Scheiding, Mónica, Cholewa, Hanna, Alarcón Iranzo, Marina, Fluixá Pelegri, Ana, Fernández Miguel, Tamara, Ortega Machón, Natalia, Alonso Hernández, Natalia, García Granero, Álvaro, Civeira Taboada, Tatiana, Rojo Fernández, Yago, Navas Cuellar, Jose Aurelio, Castillo, Celia, Pascual Miguelañez, Isabel, Dios Barbeitio, Sandra, Reyes Díaz, María Luisa, García Cabrera, Ana María, Ramallo Solís, Irene María, Pérez Pérez, Teresa, Marín, Gabriel, Calero Lillo, Aranzazu, Sánchez Guillén, Luis, López Noguera, Julia, Pérez, Miguel Ángel, Cano-Valderrama, Oscar, Cerdán-Santacruz, Carlos, Fernández-Miguel, Tamara, García-Granero, Álvaro, Calderón, Teresa, and Reyes, María L.

Published
2024
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16. Interspecific Competition Between Guanacos and Livestock and Their Relative Impact on Patagonian Rangelands: Evidence, Knowledge Gaps, and Future Directions

Author

Schroeder, Natalia M., Rodríguez, Victoria, Marino, Andrea, Panebianco, Antonella, Peña, Fiama, Quintana, Flavio, Series Editor, Avila, Luciano J., Series Editor, González-José, Rolando, Series Editor, Bucci, Sandra J., Series Editor, Carmanchahi, Pablo, editor, and Lichtenstein, Gabriela, editor

Published
2022
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19. The First Protocol for In Vitro Propagation of Kalanchoe beharensis Through Adventitious Shoots, a Preliminary Study.

Author

Moreno-García, Ignacio, Rodríguez, Victoria, García-Sogo, Begoña, Ventura, Cristhian, Moreno, Vicente, and Pineda, Benito

Subjects
GROWTH regulators, KALANCHOE, PLANT spacing, CYTOKININS, AUXIN
Abstract

Kalanchoe beharensis, a vulnerable species according to the International Union for Conservation of Nature, is highly prized for its ornamental value and medicinal properties. Therefore, an efficient methodology to propagate this ecologically significant species would be of particular interest. The propagation of K. beharensis has traditionally been achieved by seed or cuttings, but these methods are limited in efficiency. Micropropagation provides a more efficient and controlled alternative by enabling the in vitro production of numerous plants in a small space and in a short period of time. Despite its advantages, no micropropagation protocol for K. beharensis has been reported in the literature. In this study, we report an efficient in vitro regeneration protocol for K. beharensis. In order to implement this, we evaluated the morphogenetic response of leaf and root explants in media supplemented with auxins, cytokinins, or a combination of both growth regulators. Surprisingly, the best results were observed in indole-3-acetic acid-supplemented media. Adventitious shoots were rooted in either hormone-free or auxin-supplemented media, with indole-3-acetic acid yielding the best results. Rooted plants were acclimatized in the greenhouse, achieving over 80% survival during acclimatization. This protocol improves multiplication rate, space utilization, and uniformity, providing a viable alternative to conventional propagation methods. [ABSTRACT FROM AUTHOR]

Published
2024
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20. Acidogenic Fermentation of Cassava Wastewater: Effect of the Substrate-to-Microorganism Ratio and Temperature on Volatile Fatty Acids Production.

Author

Sanchez-Ledesma, Lina Marcela, Rodríguez-Victoria, Jenny Alexandra, and Ramírez-Malule, Howard

Subjects
CASSAVA starch, PROPIONIC acid, TECHNOLOGICAL innovations, FATTY acids, BATCH reactors
Abstract

The production of volatile fatty acids (VFAs) through the acidogenic fermentation of wastewater is an emerging technology that requires further research to optimize operational variables for specific substrates. Cassava wastewater, which is a byproduct of the cassava sour starch extraction process, has been minimally studied regarding its potential for VFA production through acidogenic fermentation. Batch reactors were used to evaluate the effects of the substrate-to-microorganism (S/M) ratio and temperature on VFA production from cassava wastewater. The results showed no statistically significant differences between the evaluated S/M ratios. The maximum total VFA concentration observed was 2214.64 mg of acetic acid (HAc)/L (0.32 gCODVFA/gCOD), which was achieved at a S/M ratio of 4 gCOD/gVS. This concentration was predominantly composed of acetic acid (42.7%), followed by butyric acid (30.1%) and propionic acid (24.6%), with a minor quantity of isovaleric acid (2.6%). The statistical analysis for the temperature variable showed significant differences between the evaluated conditions. The maximum concentration of total VFAs was 2650.19 mgHAc/L (0.45 gCODVFA/gCOD) at 34 ± 1 °C, with acetic (40.9%), butyric (29.8%), and propionic (29.3%) acids as primary metabolites. Cassava wastewater shows promise as a potential substrate for VFA production, warranting evaluation in continuous reactors. [ABSTRACT FROM AUTHOR]

Published
2024
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21. Smart Viniculture: Applying Artificial Intelligence for Improved Winemaking and Risk Management.

Author

Izquierdo-Bueno, Inmaculada, Moraga, Javier, Cantoral, Jesús M., Carbú, María, Garrido, Carlos, and González-Rodríguez, Victoria E.

Subjects
SUSTAINABILITY, ARTIFICIAL intelligence, GRAPE growing, SUSTAINABLE agriculture, GRAPE harvesting, VITICULTURE
Abstract

Featured Application: This review elucidates the transformative impact of artificial intelligence (AI) on viticulture, showcasing its practical applications in disease prediction, pest management, automated grape harvesting, and the optimization of water and nutrient management. The implementation of AI-driven technologies enables vineyard managers to effectively mitigate challenges such as disease outbreaks and pest infestations, resulting in healthier vines and increased yields. Automated harvesting systems improve the efficiency and consistency of grape picking, which are essential for the production of high-quality wine. Furthermore, AI's data-centric approaches to resource management promote sustainable practices by optimizing water and nutrient use. These developments illustrate the potential of AI to revolutionize traditional viticultural practices, addressing the industry's increasing demands for quality and sustainability in winemaking. This review explores the transformative role of artificial intelligence (AI) in the entire winemaking process, from viticulture to bottling, with a particular focus on enhancing food safety and traceability. It discusses AI's applications in optimizing grape cultivation, fermentation, bottling, and quality control, while emphasizing its critical role in managing microbiological risks such as mycotoxins. The review aims to show how AI technologies not only refine operational efficiencies but also raise safety standards and ensure traceability from vineyard to consumer. Challenges in AI implementation and future directions for integrating more advanced AI solutions into the winemaking industry will also be discussed, providing a comprehensive overview of AI's potential to revolutionize traditional practices. [ABSTRACT FROM AUTHOR]

Published
2024
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26. Cáncer hereditario y microbiota. Evaluación de una intervención nutricional

Author

Gallego Rodríguez, Victoria, Infante Sanz, María del Mar, Universidad de Valladolid. Facultad de Medicina, Gallego Rodríguez, Victoria, Infante Sanz, María del Mar, and Universidad de Valladolid. Facultad de Medicina

Abstract

La microbiota intestinal, constituida por una diversidad de microorganismo, juega un papel crucial en la salud, incluyendo funciones metabólicas, inmunológicas y protectoras contra patógenos. Sin embargo, su alteración o disbiosis ha sido asociado con diversos canceres hereditarios, como el cáncer colorrectal, de mama y ovario. El cáncer colorrectal hereditario incluye el síndrome Lynch y la poliposis adenomatosa familiar, ambos asociados a mutaciones genéticas, como en los genes MLH1 y MSH2 en el síndrome de Lynch, que predisponen a la formación de tumores. Mientras que los genes BRCA1 y BRCA2 son los más estudiados en relación con el cáncer de mama y ovario hereditario. La relación entre la microbiota y el cáncer hereditario es bidireccional: la microbiota puede influir en la carcinogénesis a través de mecanismo pro-tumorales y antitumorales. Por ejemplo, bacterias como Helicobacter pylori y Escherichia coli producen toxinas que inducen daño en el ADN y promueven la inflamación crónica. Por otro lado, metabolitos como el butirato y propionato, han demostrado tener efectos antitumorales al inhibir la proliferación celular y promover respuestas inmunitarias contra las células tumorales. Una dieta alta en grasa, azucares y alimentos procesados aumenta el riesgo de cáncer, mientras que la dieta mediterránea ofrece porrección contra varias enfermedades, incluyendo ciertos canceres. Las dietas vegetarianas también tienen propiedades anticancerígenas debido a su alto contenido en antioxidantes. Por lo tanto, la intervención nutricional dirigida a modificar la microbiota podría representar una vía prometedora para la prevención y el manejo del cáncer en pacientes con predisposición genética., Grado en Nutrición Humana y Dietética

Published
2024

27. Microbial impact on initial soil formation in arid and semiarid environments under simulated climate change

Author

Rodríguez, Victoria, Bartholomäus, Alexander, Witzgall, Kristina, Riveras-Muñoz, Nicolás, Oses, Romulo, Liebner, Susanne, Kallmeyer, Jens, Rach, Oliver, Mueller, Carsten W., Seguel, Oscar, Scholten, Thomas, Wagner, Dirk, Rodríguez, Victoria, Bartholomäus, Alexander, Witzgall, Kristina, Riveras-Muñoz, Nicolás, Oses, Romulo, Liebner, Susanne, Kallmeyer, Jens, Rach, Oliver, Mueller, Carsten W., Seguel, Oscar, Scholten, Thomas, and Wagner, Dirk

Abstract

The microbiota is attributed to be important for initial soil formation under extreme climate conditions, but experimental evidence for its relevance is scarce. To fill this gap, we investigated the impact of in situ microbial communities and their interrelationship with biocrust and plants compared to abiotic controls on soil formation in initial arid and semiarid soils. Additionally, we assessed the response of bacterial communities to climate change. Topsoil and subsoil samples from arid and semiarid sites in the Chilean Coastal Cordillera were incubated for 16 weeks under diurnal temperature and moisture variations to simulate humid climate conditions as part of a climate change scenario. Our findings indicate that microorganism-plant interaction intensified aggregate formation and stabilized soil structure, facilitating initial soil formation. Interestingly, microorganisms alone or in conjunction with biocrust showed no discernible patterns compared to abiotic controls, potentially due to water-masking effects. Arid soils displayed reduced bacterial diversity and developed a new community structure dominated by Proteobacteria, Actinobacteriota, and Planctomycetota, while semiarid soils maintained a consistently dominant community of Acidobacteriota and Proteobacteria. This highlighted a sensitive and specialized bacterial community in arid soils, while semiarid soils exhibited a more complex and stable community. We conclude that microorganism-plant interaction has measurable impacts on initial soil formation in arid and semiarid regions on short time scales under climate change. Additionally, we propose that soil and climate legacies are decisive for the present soil microbial community structure and interactions, future soil development, and microbial responses.

Published
2024

28. Formulation of a protocol to evaluate the aerobic granulation potential (AGP) of an inoculum

Author

Dayana Grisales Penagos, Jenny Rodríguez Victoria, and Mateo Villarraga Manrique

Subjects
Aerobic granules, Inoculum, Protocol, Science
Abstract

This paper proposes and develops a protocol for measuring the aerobic granulation potential of sludge, aiming to provide an affordable and simple alternative that can facilitate the development of aerobic granulation technology. In this sense, the protocol comprises a set of parameters and considerations that interact to create a controlled environment and stimulate cell population clustering. All of this is done in the context of procedural simplicity, low cost, and the speed at which results are obtained. The protocol is essentially a three-stage method: preparation of the substrate, adaptation of the inoculum, and implementation of the protocol. Simple parameters were measured to evaluate the granulation process: SVI, settling velocity, and morphological parameters. The protocol was validated according to optimal ranges and criteria previously established in the literature. For this purpose, an activated sludge inoculum from a domestic wastewater treatment plant was submitted to the protocol, obtaining an optimal response of the biomass (SVI5 =13.90 mL g−1, settling velocity= 25,79 m h−1, Diameter > 0.2 mm) in a relatively short time (7 d). The results show that this protocol can constitute a tool for evaluation and decision-making using traditional laboratory equipment and is applicable at different scales.

Published
2022
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30. Microbial impact on initial soil formation in arid and semiarid environments under simulated climate change

Author

Rodríguez, Victoria, primary, Bartholomäus, Alexander, additional, Witzgall, Kristina, additional, Riveras-Muñoz, Nicolás, additional, Oses, Romulo, additional, Liebner, Susanne, additional, Kallmeyer, Jens, additional, Rach, Oliver, additional, Mueller, Carsten W., additional, Seguel, Oscar, additional, Scholten, Thomas, additional, and Wagner, Dirk, additional

Published
2024
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32. New Eremophilane-Type Sesquiterpenes from the Marine Sediment-Derived Fungus Emericellopsis maritima BC17 and Their Cytotoxic and Antimicrobial Activities

Author

Virués-Segovia, Jorge R., primary, Millán, Carlos, additional, Pinedo, Cristina, additional, González-Rodríguez, Victoria E., additional, Papaspyrou, Sokratis, additional, Zorrilla, David, additional, Mackenzie, Thomas A., additional, Ramos, María C., additional, de la Cruz, Mercedes, additional, Aleu, Josefina, additional, and Durán-Patrón, Rosa, additional

Published
2023
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33. Factors related to the development of high antibody titres against SARS‐CoV‐2 in convalescent plasma donors from the ConPlas‐19 trial

Author

Romera Martínez, Irene, primary, Avendaño‐Solá, Cristina, additional, Villegas Da Ros, Carolina, additional, Bosch Llobet, Alba, additional, García Erce, José Antonio, additional, González Fraile, María Isabel, additional, Guerra Domínguez, Luisa, additional, Vicuña Andrés, Isabel, additional, Anguita Velasco, Javier, additional, González Rodríguez, Victoria Paz, additional, Contreras, Enric, additional, Urcelay Uranga, Sabin, additional, Pajares Herraiz, Ángel Luis, additional, Jimenez‐Marco, Teresa, additional, Ojea Pérez, Ana María, additional, Arroyo Rodríguez, José Luis, additional, Pérez‐Olmeda, Mayte, additional, Ramos‐Martínez, Antonio, additional, Velasco‐Iglesias, Ana, additional, Bueno Cabrera, José Luis, additional, and Duarte, Rafael F., additional

Published
2023
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37. Las tendencias de los estilos de vida y su influencia en el sector turismo

Author

Arenas Gaitán, Jorge, Universidad de Sevilla. Departamento de Administración de Empresas y Comercialización e Investigación de Mercados (Marketing), Ordóñez Rodríguez, Victoria, Arenas Gaitán, Jorge, Universidad de Sevilla. Departamento de Administración de Empresas y Comercialización e Investigación de Mercados (Marketing), and Ordóñez Rodríguez, Victoria

Abstract

En este trabajo de fin de grado se ha realizado un estudio de mercado del sector turismo relacionándolo con los estilos de vida y el nicho hotelero. La razón de este reside en encontrar información acerca del impacto de los estilos de vida en la elección de destinos turísticos y el comportamiento del turista. Cada apartado del trabajo se aborda desde la perspectiva del marketing.

Published
2023

38. Synergistic effects of childhood adversity and polygenic risk in first-episode psychosis: the EU-GEI study

Author

European Commission, South-Eastern Norway Regional Health Authority, Brain and Behavior Research Foundation, Aas, Monica [0000-0002-2338-5826], Aas, Monica, Alameda, Luis, Di Forti, Marta, Quattrone, Diego, Dazzan, Paola, Trotta, Antonella, Ferraro, Laura, Rodríguez, Victoria, Vassos, Evangelos, Sham, Pak C., Tripoli, Giada, La Cascia, Caterina, La Barbera, Daniele, Tarricone, Ilaria, Muratori, Roberto, Berardi, Domenico, Lasalvia, Antonio, Tosato, Sarah, Szöke, Andrei, Llorca, Pierre-Michel, Arango, Celso, Tortelli, Andrea, Haan, Lieuwe de, Velthorst, Eva, Bobes, Julio, Bernardo, Miguel, Sanjuán, Julio, Santos, José Luis, Arrojo, Manuel, Del-Ben, Cristina Marta, Menezes, Paulo Rossi, Selten, Jean-Paul, Jones, Peter B., Jongsma, Hannah E., Kirkbride, James B., Rutten, Bart P. F., Os, Jim van, Gayer-Anderson, Charlotte, Murray, Robin M., Morgan, Craig, European Commission, South-Eastern Norway Regional Health Authority, Brain and Behavior Research Foundation, Aas, Monica [0000-0002-2338-5826], Aas, Monica, Alameda, Luis, Di Forti, Marta, Quattrone, Diego, Dazzan, Paola, Trotta, Antonella, Ferraro, Laura, Rodríguez, Victoria, Vassos, Evangelos, Sham, Pak C., Tripoli, Giada, La Cascia, Caterina, La Barbera, Daniele, Tarricone, Ilaria, Muratori, Roberto, Berardi, Domenico, Lasalvia, Antonio, Tosato, Sarah, Szöke, Andrei, Llorca, Pierre-Michel, Arango, Celso, Tortelli, Andrea, Haan, Lieuwe de, Velthorst, Eva, Bobes, Julio, Bernardo, Miguel, Sanjuán, Julio, Santos, José Luis, Arrojo, Manuel, Del-Ben, Cristina Marta, Menezes, Paulo Rossi, Selten, Jean-Paul, Jones, Peter B., Jongsma, Hannah E., Kirkbride, James B., Rutten, Bart P. F., Os, Jim van, Gayer-Anderson, Charlotte, Murray, Robin M., and Morgan, Craig

Abstract

[Background] A history of childhood adversity is associated with psychotic disorder, with an increase in risk according to the number of exposures. However, it is not known why only some exposed individuals go on to develop psychosis. One possibility is pre-existing polygenic vulnerability. Here, we investigated, in the largest sample of first-episode psychosis (FEP) cases to date, whether childhood adversity and high polygenic risk scores for schizophrenia (SZ-PRS) combine synergistically to increase the risk of psychosis, over and above the effect of each alone., [Methods] We assigned a schizophrenia-polygenic risk score (SZ-PRS), calculated from the Psychiatric Genomics Consortium (PGC2), to all participants in a sample of 384 FEP patients and 690 controls from the case–control component of the EU-GEI study. Only participants of European ancestry were included in the study. A history of childhood adversity was collected using the Childhood Trauma Questionnaire (CTQ). Synergistic effects were estimated using the interaction contrast ratio (ICR) [odds ratio (OR)exposure and PRS − ORexposure − ORPRS + 1] with adjustment for potential confounders., [Results] There was some evidence that the combined effect of childhood adversities and polygenic risk was greater than the sum of each alone, as indicated by an ICR greater than zero [i.e. ICR 1.28, 95% confidence interval (CI) −1.29 to 3.85]. Examining subtypes of childhood adversities, the strongest synergetic effect was observed for physical abuse (ICR 6.25, 95% CI −6.25 to 20.88)., [Conclusions] Our findings suggest possible synergistic effects of genetic liability and childhood adversity experiences in the onset of FEP, but larger samples are needed to increase precision of estimates.

Published
2023

39. Association Between Childhood Adversity and Functional Outcomes in People With Psychosis: A Meta-analysis

Author

Fundación Alicia Koplowitz, Janssen Biotech, Deakin University, Rotary Club of Geelong, Brain and Behavior Research Foundation, Medical Research Council (UK), Christy, Angeline, Cavero, Daniela, Navajeeva, Sujeena, Murray-O'Shea, Rachel, Rodríguez, Victoria, Aas, Monica, Trotta, Giulia, Moudiab, Socayna, Garrido-Torres, Nathalia, Zamora, Blanca, Sideli, Lucia, Wrobel, Anna L., Salazar de Pablo, Gonzalo, Alameda, Luis, Fundación Alicia Koplowitz, Janssen Biotech, Deakin University, Rotary Club of Geelong, Brain and Behavior Research Foundation, Medical Research Council (UK), Christy, Angeline, Cavero, Daniela, Navajeeva, Sujeena, Murray-O'Shea, Rachel, Rodríguez, Victoria, Aas, Monica, Trotta, Giulia, Moudiab, Socayna, Garrido-Torres, Nathalia, Zamora, Blanca, Sideli, Lucia, Wrobel, Anna L., Salazar de Pablo, Gonzalo, and Alameda, Luis

Abstract

Despite the accepted link between childhood adversity (CA) and psychotic disorders, evidence on the relationship between CA and poor functional outcome remains less consistent and has never been reviewed quantitatively. The aim of this meta-analysis was to systematically examine the association between CA and functional outcomes in people with psychotic disorders.

Published
2023

40. Negative symptoms in children and adolescents with early-onset psychosis and at clinical high-risk for psychosis: systematic review and meta-analysis

Author

Salazar de Pablo, Gonzalo, Catalán, Ana, Vaquerizo-Serrano, Julio David, Pedruzo, Borja, Alameda, Luis, Sandroni, Veronica, Armendariz, Álvaro, Rodríguez, Victoria, Arango, Celso, Moreno, Carmen, Downs, Johnny, Abbott, Chris, Shin, Jae Il, Solmi, Marco, Fusar-Poli, Paolo, Correll, Christoph U., Salazar de Pablo, Gonzalo, Catalán, Ana, Vaquerizo-Serrano, Julio David, Pedruzo, Borja, Alameda, Luis, Sandroni, Veronica, Armendariz, Álvaro, Rodríguez, Victoria, Arango, Celso, Moreno, Carmen, Downs, Johnny, Abbott, Chris, Shin, Jae Il, Solmi, Marco, Fusar-Poli, Paolo, and Correll, Christoph U.

Abstract

[Background] Early-onset psychosis (EOP) refers to the development of a first episode of psychosis before 18 years of age. Individuals at clinical high risk for psychosis (CHR-P) include adolescents and young adults, although most evidence has focused on adults. Negative symptoms are important prognostic indicators in psychosis. However, research focusing on children and adolescents is limited., [Aims] To provide meta-analytical evidence and a comprehensive review of the status and advances in the diagnosis, prognosis and treatment of negative symptoms in children and adolescents with EOP and at CHR-P., [Method] PRISMA/MOOSE-compliant systematic review (PROSPERO: CRD42022360925) from inception to 18 August 2022, in any language, to identify individual studies conducted in EOP/CHR-P children and adolescents (mean age <18 years) providing findings on negative symptoms. Findings were systematically appraised. Random-effects meta-analyses were performed on the prevalence of negative symptoms, carrying out sensitivity analyses, heterogeneity analyses, publication bias assessment and quality assessment using the Newcastle–Ottawa Scale., [Results] Of 3289 articles, 133 were included (n = 6776 EOP, mean age 15.3 years (s.d. = 1.6), males = 56.1%; n = 2138 CHR-P, mean age 16.1 years (s.d. = 1.0), males = 48.6%). There were negative symptoms in 60.8% (95% CI 46.4%–75.2%) of the children and adolescents with EOP and 79.6% (95% CI 66.3–92.9%) of those at CHR-P. Prevalence and severity of negative symptoms were associated with poor clinical, functional and intervention outcomes in both groups. Different interventions were piloted, with variable results requiring further replication., [Conclusions] Negative symptoms are common in children and adolescents at early stages of psychosis, particularly in those at CHR-P, and are associated with poor outcomes. Future intervention research is required so that evidence-based treatments will become available.

Published
2023

41. Spray-coating of graphene nanoplatelets on sisal fibers and its influence on electromechanical behavior of biocomposite laminates.

Author

Rodríguez-González, Julio A, Renteria-Rodríguez, Victoria, Rubio-González, Carlos, and Franco-Urquiza, Edgar A

Subjects
*SISAL (Fiber), *ELECTRICAL conductivity transitions, *NANOPARTICLES, *GRAPHENE, *GLASS transition temperature, *NATURAL fibers
Abstract

Spray coating and vacuum-assisted resin infusion processes were implemented in this work to develop multifunctional biocomposite laminates. The biocomposites were fabricated using a bio-based epoxy resin reinforced with natural sisal fibers coated with graphene nanoplatelets (GNPs). A systematic characterization of material properties was performed to evaluate the mechanical, thermomechanical, electrical, and piezoresistive behavior of biocomposites with different GNPs contents (0, 1, 4, 6, and 8 wt.%). The mechanical tests revealed that adding GNPs to biocomposites has a slight positive effect on their flexural properties compared to the neat biocomposites (without GNPs). The electrical and thermomechanical tests showed that the electrical conductivity and glass transition temperature of biocomposites containing GNPs were enhanced significantly, achieving average values of 5.19 x 10-4 S/m and 63.29°C (26%), respectively. Regarding electromechanical tests, the biocomposites with 8 wt.% GNPs exhibited an excellent piezoresistive behavior under monotonic loading conditions, achieving a gage factor (strain sensitivity) of 3.56. Bending tests with cyclic loading were also performed, and cyclic reproducibility of the piezoresistive response of the biocomposites after 10 cycles was demonstrated, evidencing that the incorporation of GNPs onto sisal fibers by spray-coating produces an effective formation of conductive networks into biocomposites suitable for sensing applications. [ABSTRACT FROM AUTHOR]

Published
2024
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42. Factors related to the development of high antibody titres against SARS‐CoV‐2 in convalescent plasma donors from the ConPlas‐19 trial.

Author

Romera Martínez, Irene, Avendaño‐Solá, Cristina, Villegas Da Ros, Carolina, Bosch Llobet, Alba, García Erce, José Antonio, González Fraile, María Isabel, Guerra Domínguez, Luisa, Vicuña Andrés, Isabel, Anguita Velasco, Javier, González Rodríguez, Victoria Paz, Contreras, Enric, Urcelay Uranga, Sabin, Pajares Herraiz, Ángel Luis, Jimenez‐Marco, Teresa, Ojea Pérez, Ana María, Arroyo Rodríguez, José Luis, Pérez‐Olmeda, Mayte, Ramos‐Martínez, Antonio, Velasco‐Iglesias, Ana, and Bueno Cabrera, José Luis

Subjects
CONVALESCENT plasma, ANTIBODY titer, SARS-CoV-2
Abstract

Background and Objectives: The efficacy of COVID‐19 convalescent plasma (CP) associates with high titres of antibodies. ConPlas‐19 clinical trial showed that CP reduces the risk of progression to severe COVID‐19 at 28 days. Here, we aim to study ConPlas‐19 donors and characteristics that associate with high anti‐SARS‐CoV‐2 antibody levels. Materials and Methods: Four‐hundred donors were enrolled in ConPlas‐19. The presence and titres of anti‐SARS‐CoV‐2 antibodies were evaluated by EUROIMMUN anti‐SARS‐CoV‐2 S1 IgG ELISA. Results: A majority of 80.3% of ConPlas‐19 donor candidates had positive EUROIMMUN test results (ratio ≥1.1), and of these, 51.4% had high antibody titres (ratio ≥3.5). Antibody levels decline over time, but nevertheless, out of 37 donors tested for an intended second CP donation, over 90% were still EUROIMMUN positive, and nearly 75% of those with high titres maintained high titres in the second sample. Donors with a greater probability of developing high titres of anti‐SARS‐CoV‐2 antibodies include those older than 40 years of age (RR 2.06; 95% CI 1.24–3.42), with more than 7 days of COVID‐19 symptoms (RR 1.89; 95% CI 1.05–3.43) and collected within 4 months from infection (RR 2.61; 95% CI 1.16–5.90). Male donors had a trend towards higher titres compared with women (RR 1.67; 95% CI 0.91–3.06). Conclusion: SARS‐CoV‐2 CP candidate donors' age, duration of COVID‐19 symptoms and time from infection to donation associate with the collection of CP with high antibody levels. Beyond COVID‐19, these data are relevant to inform decisions to optimize the CP donor selection process in potential future outbreaks. [ABSTRACT FROM AUTHOR]

Published
2024
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43. In Vitro Studies of Endophytic Bacteria Isolated from Ginger (Zingiber officinale) as Potential Plant-Growth-Promoting and Biocontrol Agents against Botrytis cinerea and Colletotrichum acutatum.

Author

Bódalo, Alejandro, Borrego, Rogelio, Garrido, Carlos, Bolivar-Anillo, Hernando José, Cantoral, Jesús M., Vela-Delgado, María Dolores, González-Rodríguez, Victoria E., and Carbú, María

Subjects
ENDOPHYTIC bacteria, COLLETOTRICHUM acutatum, BOTRYTIS cinerea, BIOLOGICAL pest control agents, GINGER, PHYTOPATHOGENIC fungi, PHYTOPATHOGENIC bacteria, NITROGEN fixation
Abstract

Agriculture currently confronts a multitude of challenges arising from the excessive utilization of chemical pesticides and the proliferation of phytopathogenic fungi strains that exhibit resistance to commonly employed active compounds in the field. Botrytis cinerea and Colletotrichum acutatum are phytopathogenic fungi that inflict substantial economic losses within agriculture and food due to their high impacts on crops both pre- and post-harvest. Furthermore, the emergence of fungal strains that are resistant to commercial fungicides has exacerbated this problem. To explore more environmentally sustainable alternatives for the control of these pathogens, an investigation into the endophytic bacteria associated with ginger (Zingiber officinale Rosc.) was conducted. The primary focus of this study involved evaluating their inhibitory efficacy against the fungi and assessing their potential for promoting plant growth. The endophytic bacteria genera Lelliottia, Lysinibacillus, Kocuria, Agrococcus, Acinetobacter, Agrobacterium, Zymobacter, and Mycolicibacterium were identified. All isolates showed remarkable in vitro antagonistic ability against B. cinerea (>94%) and C. acutatum (>74%). Notably, the Lelliottia amnigena J29 strain exhibited a notable proficiency in producing extracellular enzymes and indole compounds (IAA), solubilizing phosphate and potassium, and forming biofilm. Furthermore, the Lysinibacillus capsici J26, Agrococcus citreus J28, and Mycolicibacterium sp. J5 strains displayed the capacity for atmospheric nitrogen fixation and siderophore production. These findings underscore the agricultural and biotechnological potential of endophytic bacteria derived from ginger plants and suggest the feasibility of developing alternative approaches to manage these two phytopathogenic fungi. [ABSTRACT FROM AUTHOR]

Published
2023
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44. Front Cover: Facile, Single‐Step Synthesis of a Series of D‐Ring Ethisterones Substituted with 1,4‐1,2,3‐Triazoles: Preliminary Evaluation of Cytotoxic Activities (ChemMedChem 8/2023)

Author

Canseco‐González, Daniel, primary, Rodríguez‐Victoria, Isaac, additional, Apan‐Ramírez, Teresa, additional, Viviano‐Posadas, Alejandro O., additional, Serrano‐García, Juan S., additional, Arenaza‐Corona, Antonino, additional, Orjuela, Adrian L., additional, Alí‐Torres, Jorge, additional, Dorazco‐González, Alejandro, additional, and Morales‐Morales, David, additional

Published
2023
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47. Facile, Single‐Step Synthesis of a Series of D‐Ring Ethisterones Substituted with 1,4‐1,2,3‐Triazoles: Preliminary Evaluation of Cytotoxic Activities

Author

Canseco‐González, Daniel, primary, Rodríguez‐Victoria, Isaac, additional, Apan‐Ramírez, Teresa, additional, Viviano‐Posadas, Alejandro O., additional, Serrano‐García, Juan S., additional, Arenaza‐Corona, Antonino, additional, Orjuela, Adrian L., additional, Alí‐Torres, Jorge, additional, Dorazco‐González, Alejandro, additional, and Morales‐Morales, David, additional

Published
2023
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48. Front Cover: Facile, Single‐Step Synthesis of a Series of D‐Ring Ethisterones Substituted with 1,4‐1,2,3‐Triazoles: Preliminary Evaluation of Cytotoxic Activities (ChemMedChem 8/2023)

Author

Daniel Canseco‐González, Isaac Rodríguez‐Victoria, Teresa Apan‐Ramírez, Alejandro O. Viviano‐Posadas, Juan S. Serrano‐García, Antonino Arenaza‐Corona, Adrian L. Orjuela, Jorge Alí‐Torres, Alejandro Dorazco‐González, and David Morales‐Morales

Subjects
Pharmacology, Organic Chemistry, Drug Discovery, Molecular Medicine, General Pharmacology, Toxicology and Pharmaceutics, Biochemistry
Published
2023
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49. Facile, Single‐Step Synthesis of a Series of D‐Ring Ethisterones Substituted with 1,4‐1,2,3‐Triazoles: Preliminary Evaluation of Cytotoxic Activities

Author

Daniel Canseco‐González, Isaac Rodríguez‐Victoria, Teresa Apan‐Ramírez, Alejandro O. Viviano‐Posadas, Juan S. Serrano‐García, Antonino Arenaza‐Corona, Adrian L. Orjuela, Jorge Alí‐Torres, Alejandro Dorazco‐González, and David Morales‐Morales

Subjects
Pharmacology, Organic Chemistry, Drug Discovery, Molecular Medicine, General Pharmacology, Toxicology and Pharmaceutics, Biochemistry
Published
2023
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