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2. Thrombectomy alone versus intravenous alteplase plus thrombectomy in patients with stroke: an open-label, blinded-outcome, randomised non-inferiority trial

Author

Alonso, Angelika, Arquizan, Caroline, Barreau, Xavier, Beaujeux, Rémy, Behme, Daniel, Boeckh-Behrens, Tobias, Boehme, Christian, Boix, Martí, Boulouis, Grégoire, Bricout, Nicolas, Broc, Nicolas, Cereda, Carlo W., Chabert, Emmanuel, Cho, Tae-Hee, Cianfoni, Alessandro, Costalat, Vincent, Denier, Christian, Di Maria, Frederico, du Mesnil de Rochemont, Richard, Fearon, Patricia, Ferrier, Anna, Fischer, Sebastian, Gauberti, Maxime, Gaudron, Marie, Gimenez, Laetitia, Globas, Christoph, Görtler, Michael, Goyal, Mayank, Hilker-Roggendorf, Ruediger, Hill, Michael D., Hua, Vi Tuan, Humbertjean, Lisa, Jansen, Olav, Jung, Simon, Kägi, Georg, Kelly, Michael E., Kleffner, Ilka, Knoflach, Michael, Nedeltchev, Krassen, Krause, Lars Udo, Lappalainen, Kimmo, Lefebvre, Margaux, Leyon, Joe, Liao, Liang, Liegey, Jean-Sebastien, Loehr, Christian, Michel, Patrik, Nannoni, Stefania, Nicholson, Patrick, Nico, Lorena, Obadia, Michael, Ognard, Julien, Ogungbemi, Ayokunle, Olivot, Jean-Marc, Escalard, Simon, Pasi, Marco, Peeling, Lissa, Perez, Jane, Petersen, Martina, Piechowiak, Eike, Raposo, Roberto, Räty, Silja, Reitz, Sarah C., Remollo, Sebastià, Remonda, Luca, Rennie, Ian, Requena, Manuel, Riabikin, Alexander, Riva, Roberto, Rouchaud, Aymeric, Rosi, Andrea, Rubiera, Marta, Spelle, Laurent, Schnieder, Marlena, Schaafsma, Joanna D., Schubert, Tilman, Schulz, Jörg B., Siddiqui, Mohammed, Soize, Sébastien, Sonnberger, Michael, Touze, Emmanuel, Triquenot, Aude, Turc, Guillaume, Vieira, Lucy, Ben Hassen, Wagih, Wagner, Judith N., Wasser, Katrin, Weber, Johannes, Wenz, Holger, Weisenburger-Lile, David, Wodarg, Fritz, Wolff, Valérie, Wunderlich, Silke, Fischer, Urs, Kaesmacher, Johannes, Strbian, Daniel, Eker, Omer, Cognard, Christoph, Plattner, Patricia S, Bütikofer, Lukas, Mordasini, Pasquale, Deppeler, Sandro, Pereira, Vitor M, Albucher, Jean François, Darcourt, Jean, Bourcier, Romain, Benoit, Guillon, Papagiannaki, Chrysanthi, Ozkul-Wermester, Ozlem, Sibolt, Gerli, Tiainen, Marjaana, Gory, Benjamin, Richard, Sébastien, Liman, Jan, Ernst, Marielle Sophie, Boulanger, Marion, Barbier, Charlotte, Mechtouff, Laura, Zhang, Liqun, Marnat, Gaultier, Sibon, Igor, Nikoubashman, Omid, Reich, Arno, Consoli, Arturo, Lapergue, Bertrand, Ribo, Marc, Tomasello, Alejandro, Saleme, Suzana, Macian, Francisco, Moulin, Solène, Pagano, Paolo, Saliou, Guillaume, Carrera, Emmanuel, Janot, Kevin, Hernández-Pérez, María, Pop, Raoul, Schiava, Lucie Della, Luft, Andreas R, Piotin, Michel, Gentric, Jean Christophe, Pikula, Aleksandra, Pfeilschifter, Waltraud, Arnold, Marcel, Siddiqui, Adnan H, Froehler, Michael T, Furlan, Anthony J, Chapot, René, Wiesmann, Martin, Machi, Paolo, Diener, Hans-Christoph, Kulcsar, Zsolt, Bonati, Leo H, Bassetti, Claudio L, Mazighi, Mikael, Liebeskind, David S, Saver, Jeffrey L, and Gralla, Jan

Published
2022
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3. To suture or not to suture? Does globe immobilisation technique affect clinical outcome in stereotactic radiosurgery for uveal melanoma?

Author

Quhill, Hibba, Salvi, Sachin M, Rennie, Ian G, Yianni, John, Radatz, Matthias, and Rundle, Paul

Subjects
TREATMENT effectiveness, UVEA cancer, STEREOTACTIC radiosurgery, SUTURING, SUTURES, MELANOMA, EYE tracking
Abstract

Stereotactic radiosurgery (SRS) is a valuable treatment option for uveal melanoma, offering excellent tumour control rates and eye preservation. Its efficacy relies upon accurate localisation of the tumour, which is challenging in the mobile eye. Various methods of globe immobilisation have been used, including non-invasive devices, such as eye movement tracking and suction cups, but common practice is to use local anaesthetic block with or without transconjunctival suturing of the extraocular muscles. Some studies have suggested that the addition of muscle suturing to local anaesthetic block provides better immobilisation of the globe, when compared to anaesthetic block alone. Controversy exists regarding the clinical relevance of this observation and ocular oncologists differ in their choice of immobilisation technique. In order to establish if the addition of muscle suturing to local anaesthetic block improves clinical outcomes, we performed a retrospective review of all cases that underwent SRS for uveal melanoma over a 10-year period (May 2008 to May 2018). Based on surgeon preference, all patients received either local anaesthetic block plus muscle suturing (Group A) or local anaesthetic block alone (Group B) to induce globe akinesia. Outcomes assessed were primary treatment failure, tumour recurrence, secondary enucleation and death rate. In our cohort of 290 eyes; 118 patients were in group A and 172 patients were in group B. There were no cases of primary treatment failure in either group. With a minimum of 24 months follow-up, only 3 patients experienced tumour recurrence (1 in group A and 2 in group B). There was no significant difference in recurrence, enucleation and all-cause death rates between the two groups. Our retrospective review suggests that although extraocular muscle suturing may be considered by some units to provide superior globe immobilisation for SRS, it does not alter the clinical outcome. [ABSTRACT FROM AUTHOR]

Published
2024
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5. Thrombectomy alone versus intravenous alteplase plus thrombectomy in patients with stroke: an open-label, blinded-outcome, randomised non-inferiority trial

Author

Fischer, Urs, primary, Kaesmacher, Johannes, additional, Strbian, Daniel, additional, Eker, Omer, additional, Cognard, Christoph, additional, Plattner, Patricia S, additional, Bütikofer, Lukas, additional, Mordasini, Pasquale, additional, Deppeler, Sandro, additional, Pereira, Vitor M, additional, Albucher, Jean François, additional, Darcourt, Jean, additional, Bourcier, Romain, additional, Benoit, Guillon, additional, Papagiannaki, Chrysanthi, additional, Ozkul-Wermester, Ozlem, additional, Sibolt, Gerli, additional, Tiainen, Marjaana, additional, Gory, Benjamin, additional, Richard, Sébastien, additional, Liman, Jan, additional, Ernst, Marielle Sophie, additional, Boulanger, Marion, additional, Barbier, Charlotte, additional, Mechtouff, Laura, additional, Zhang, Liqun, additional, Marnat, Gaultier, additional, Sibon, Igor, additional, Nikoubashman, Omid, additional, Reich, Arno, additional, Consoli, Arturo, additional, Lapergue, Bertrand, additional, Ribo, Marc, additional, Tomasello, Alejandro, additional, Saleme, Suzana, additional, Macian, Francisco, additional, Moulin, Solène, additional, Pagano, Paolo, additional, Saliou, Guillaume, additional, Carrera, Emmanuel, additional, Janot, Kevin, additional, Hernández-Pérez, María, additional, Pop, Raoul, additional, Schiava, Lucie Della, additional, Luft, Andreas R, additional, Piotin, Michel, additional, Gentric, Jean Christophe, additional, Pikula, Aleksandra, additional, Pfeilschifter, Waltraud, additional, Arnold, Marcel, additional, Siddiqui, Adnan H, additional, Froehler, Michael T, additional, Furlan, Anthony J, additional, Chapot, René, additional, Wiesmann, Martin, additional, Machi, Paolo, additional, Diener, Hans-Christoph, additional, Kulcsar, Zsolt, additional, Bonati, Leo H, additional, Bassetti, Claudio L, additional, Mazighi, Mikael, additional, Liebeskind, David S, additional, Saver, Jeffrey L, additional, Gralla, Jan, additional, Alonso, Angelika, additional, Arquizan, Caroline, additional, Barreau, Xavier, additional, Beaujeux, Rémy, additional, Behme, Daniel, additional, Boeckh-Behrens, Tobias, additional, Boehme, Christian, additional, Boix, Martí, additional, Boulouis, Grégoire, additional, Bricout, Nicolas, additional, Broc, Nicolas, additional, Cereda, Carlo W., additional, Chabert, Emmanuel, additional, Cho, Tae-Hee, additional, Cianfoni, Alessandro, additional, Costalat, Vincent, additional, Denier, Christian, additional, Di Maria, Frederico, additional, du Mesnil de Rochemont, Richard, additional, Fearon, Patricia, additional, Ferrier, Anna, additional, Fischer, Sebastian, additional, Gauberti, Maxime, additional, Gaudron, Marie, additional, Gimenez, Laetitia, additional, Globas, Christoph, additional, Görtler, Michael, additional, Goyal, Mayank, additional, Hilker-Roggendorf, Ruediger, additional, Hill, Michael D., additional, Hua, Vi Tuan, additional, Humbertjean, Lisa, additional, Jansen, Olav, additional, Jung, Simon, additional, Kägi, Georg, additional, Kelly, Michael E., additional, Kleffner, Ilka, additional, Knoflach, Michael, additional, Nedeltchev, Krassen, additional, Krause, Lars Udo, additional, Lappalainen, Kimmo, additional, Lefebvre, Margaux, additional, Leyon, Joe, additional, Liao, Liang, additional, Liegey, Jean-Sebastien, additional, Loehr, Christian, additional, Michel, Patrik, additional, Nannoni, Stefania, additional, Nicholson, Patrick, additional, Nico, Lorena, additional, Obadia, Michael, additional, Ognard, Julien, additional, Ogungbemi, Ayokunle, additional, Olivot, Jean-Marc, additional, Escalard, Simon, additional, Pasi, Marco, additional, Peeling, Lissa, additional, Perez, Jane, additional, Petersen, Martina, additional, Piechowiak, Eike, additional, Raposo, Roberto, additional, Räty, Silja, additional, Reitz, Sarah C., additional, Remollo, Sebastià, additional, Remonda, Luca, additional, Rennie, Ian, additional, Requena, Manuel, additional, Riabikin, Alexander, additional, Riva, Roberto, additional, Rouchaud, Aymeric, additional, Rosi, Andrea, additional, Rubiera, Marta, additional, Spelle, Laurent, additional, Schnieder, Marlena, additional, Schaafsma, Joanna D., additional, Schubert, Tilman, additional, Schulz, Jörg B., additional, Siddiqui, Mohammed, additional, Soize, Sébastien, additional, Sonnberger, Michael, additional, Touze, Emmanuel, additional, Triquenot, Aude, additional, Turc, Guillaume, additional, Vieira, Lucy, additional, Ben Hassen, Wagih, additional, Wagner, Judith N., additional, Wasser, Katrin, additional, Weber, Johannes, additional, Wenz, Holger, additional, Weisenburger-Lile, David, additional, Wodarg, Fritz, additional, Wolff, Valérie, additional, and Wunderlich, Silke, additional

Published
2022
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6. Frailty and stroke thrombectomy outcomes—an observational cohort study

Author

Joyce, Nevan, primary, Atkinson, Timothy, additional, Mc Guire, Karen, additional, Wiggam, M Ivan, additional, Gordon, Patricia L, additional, Kerr, Enda L, additional, Patterson, Cathy E, additional, McILmoyle, Jim, additional, Roberts, Gerallt E, additional, Flynn, Peter A, additional, Burns, Paul, additional, Rennie, Ian R, additional, Taylor Rowan, Martin, additional, Quinn, Terence J, additional, and Fearon, Patricia, additional

Published
2022
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