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Heavy metal pollution has become a significant concern as the world continues to industrialize, urbanize, and modernize. Heavy metal pollutants impede the growth and metabolism of plants. The bioaccumulation of heavy metals in plants may create chlorophyll antagonism, oxidative stress, underdeveloped plant growth, and reduced photosynthetic system. Finding practical solutions to protect the environment and plants from the toxic effects of heavy metals is essential for long-term sustainable development. The direct use of suitable living plants for eliminating and degrading metal pollutants from ecosystems is known as phytoremediation. Phytoremediation is a novel and promising way to remove toxic heavy metals. Plant growth-promoting rhizobacteria (PGPR) can colonize plant roots and help promote their growth. Numerous variables, such as plant biomass yield, resistance to metal toxicity, and heavy metal solubility in the soil, affect the rate of phytoremediation. Phytoremediation using the PGPR consortium can speed up the process and increase the rate of heavy metal detoxification. The PGPR consortium has significantly increased the biological accumulation of various nutrients and heavy metals. This review sheds light on the mechanisms that allow plants to uptake and sequester toxic heavy metals to improve soil detoxification. The present review aids the understanding of eco-physiological mechanisms that drive plant-microbe interactions in the heavy metal-stressed environment., (© 2024 Wiley‐VCH GmbH.)

Background and Objectives: An international, multicenter, retrospective study was conducted to evaluate the long-term clinical outcomes and tumor control rates after stereotactic radiosurgery (SRS) for trigeminal schwannoma., Methods: Patient data (N = 309) were collected from 14 international radiosurgery centers. The median patient age was 50 years (range 11-87 years). Sixty patients (19%) had prior resections. Abnormal facial sensation was the commonest complaint (49%). The anatomic locations were root (N = 40), ganglion (N = 141), or dumbbell type (N = 128). The median tumor volume was 4 cc (range, 0.2-30.1 cc), and median margin dose was 13 Gy (range, 10-20 Gy). Factors associated with tumor control, symptom improvement, and adverse radiation events were assessed., Results: The median and mean time to last follow-up was 49 and 65 months (range 6-242 months). Greater than 5-year follow-up was available for 139 patients (45%), and 50 patients (16%) had longer than 10-year follow-up. The overall tumor control rate was 94.5%. Tumors regressed in 146 patients (47.2%), remained unchanged in 128 patients (41.4%), and stabilized after initial expansion in 20 patients (6.5%). Progression-free survival rates at 3 years, 5 years, and 10 years were 91%, 86%, and 80 %. Smaller tumor volume (less than 8 cc) was associated with significantly better progression-free survival ( P = .02). Seventeen patients with sustained growth underwent further intervention at a median of 27 months (3-144 months). Symptom improvement was noted in 140 patients (45%) at a median of 7 months. In multivariate analysis primary, SRS ( P = .003) and smaller tumor volume ( P = .01) were associated with better symptom improvement. Adverse radiation events were documented in 29 patients (9%)., Conclusion: SRS was associated with long-term freedom (10 year) from additional management in 80% of patients. SRS proved to be a valuable salvage option after resection. When used as a primary management for smaller volume tumors, both clinical improvement and prevention of new deficits were optimized., (Copyright © Congress of Neurological Surgeons 2023. All rights reserved.)

Ebola virus (EBOV) causes Ebola virus disease (EVD), marked by severe hemorrhagic fever; however, the mechanisms underlying the disease remain unclear. To assess the molecular basis of EVD across time, we performed RNA sequencing on 17 tissues from a natural history study of 21 rhesus monkeys, developing new methods to characterize host-pathogen dynamics. We identified alterations in host gene expression with previously unknown tissue-specific changes, including downregulation of genes related to tissue connectivity. EBOV was widely disseminated throughout the body; using a new, broadly applicable deconvolution method, we found that viral load correlated with increased monocyte presence. Patterns of viral variation between tissues differentiated primary infections from compartmentalized infections, and several variants impacted viral fitness in a EBOV/Kikwit minigenome system, suggesting that functionally significant variants can emerge during early infection. This comprehensive portrait of host-pathogen dynamics in EVD illuminates new features of pathogenesis and establishes resources to study other emerging pathogens., Competing Interests: P.C.S. is a co-founder and shareholder of Sherlock Biosciences and Delve Bio, a board member and shareholder of Danaher Corporation, and has filed IP related to genomic sequencing and diagnostic technologies. A.K.S. reports compensation for consulting and/or scientific advisory board (SAB) membership from Merck, Honeycomb Biotechnologies, Cellarity, Repertoire Immune Medicines, Ochre Bio, Third Rock Ventures, Hovione, Relation Therapeutics, FL82, FL86, Empress Therapeutics, IntrECate Biotherapeutics, Senda Biosciences, and Dahlia Biosciences unrelated to this work. F.Z. is a scientific advisor and cofounder of Editas Medicine, Beam Therapeutics, Pairwise Plants, Arbor Biotechnologies, and Aera Therapeutics. F.Z. is a scientific advisor for Octant., (© 2023 The Authors.)

The satellite communication is embellished constantly by providing information, ensuring security, and enables the communication among huge at a particular time efficiently. The satellite navigation helps in determining the people's location. Global development, natural disasters, change in climatic conditions, agriculture crop growth, etc., are monitored using satellite observation. Hence, the satellite includes detailed information data, and it must be protected confidentially. The field of the satellite is enhanced at an astonishing pace. Satellite data play an important role in this modern world; hence, the onboard-satellite data must secure through the proper selection of error detection and estimation schema. Lightweight deep learning algorithm based on Extended Kalman Filter (KFK) is proposed to detect and estimate onboard pointing error such as an error in attitude and orbit. The Extended Kalman Filter (EKF) is widely used in the satellite system. EKF is utilized in this proposed model to detect the onboard pointing error such as attitude and orbit determination. An autonomous estimation of orbit position is possible through space-borne gravity. The information obtained through the observation of satellite data is compared with the accurate gravity model in detecting the error. The utilization of EKF reduces the dependence of the ground tracking system in satellite determination. The orbital altitude and orbital position are the most important challenges faced in the satellite determination system. The satellite model using the Extended Kalman Filter is an optimum method in estimating the orbital parameters. The errors in the linearization process are detected, and this can be overcome through the proper selection of linear expansion point with the EKF algorithmic model with the Jacobian matrix calculation. The results show that the EKF implementation helps in attaining better accuracy than other methodologies. Its contribution is enormous to many space missions, autonomous rendezvous and docking for manned and unmanned missions (e.g., ISS operations and beyond, in-orbit servicing, and in-orbit refueling), routine satellite OD operations, orbital debris removal systems, Space Situational Awareness (SSA) operations, and others., Competing Interests: The authors declare that they have no conflicts of interest., (Copyright © 2022 R. Dhanalakshmi et al.)

Aim: The present study aimed to assess and evaluate oral hygiene status and oral hygiene behaviors among children with the attention-deficit hyperactive disorder (ADHD) and children without ADHD., Materials and Methods: A total of 34 children of ages 6-14 years were included in the study. Groups I-17 children with ADHD and group II-17 healthy children. A visual examination of dental caries and traumatic injuries was performed, and the oral hygiene status of these children was determined. The parent/guardian completed a structured questionnaire regarding the child's oral hygiene practices and food habits. Data obtained from oral examination and questionnaires were compiled and subjected to statistical analysis., Results: The student t -test and the Chi-squared test showed that children with ADHD had significantly higher decayed, missing, and filled teeth (DMFT) scores and incidence of traumatic injuries without significant difference in oral hygiene status., Conclusion: There is no significant difference in oral hygiene status between both the groups but caries experience, and incidence of traumatic injuries are high in children with ADHD., How to Cite This Article: Reddy ER, Kiranmayi M, Mudusu SP, et al. Oral Health Status and Caries Experience in Children Diagnosed with Attention-deficit Hyperactive Disorder. Int J Clin Pediatr Dent 2022;15(4):438-441., Competing Interests: Source of support: Nil Conflict of interest: None, (Copyright © 2022; The Author(s).)

Aim and Objective: The purpose of the study was to compare the efficiency of modified conventional root canal shaping technique versus conventional shaping technique in primary teeth., Materials and Methods: A total of 184 primary root canals (2 groups of 92 canals each) with two-thirds of root length were selected and randomly allocated into two different shaping techniques, i.e., Group I: conventional root canal shaping technique, Group II: modified root canal shaping technique. The quality of obturation (Coll and Sadrain, 1996) and presence or absences of voids were assessed by using radiographs. The recorded data was statistically analyzed., Results: Significant difference was seen between conventional and modified conventional techniques in underfilled and optimally filled canals., Conclusion: This modified cleaning and shaping technique can be considered as alternative to conventional instrumentation technique, as it improves quality of obturation and decreases the number of voids., How to Cite This Article: Reddy ER, Raju SS, Sandipamu T, et al. Modified Conventional Root Canal Shaping Technique In Primary Teeth: An In Vivo Study. Int J Clin Pediatr Dent 2022;15(S-1):S8-S11., Competing Interests: Source of support: Nil Conflict of interest: None, (Copyright © 2022; The Author(s).)

Aim and Objective: This study was carried out to comparatively assess the efficiency of four methods of obturation viz Lentulo spiral, Navi tip syringe, Bi directional spiral, and Past inject carrier in deciduous teeth using vista scan., Materials and Methods: A total sample of 100 primary root canals [4 groups of 25 canals each] with 2/3 rd of root length were selected and randomly allocated into four different obturating techniques, i.e., Group I: Lentulo spiral, Group II: Navi tip syringe, Group III: Bi directional spiral, and Group IV: Past inject carrier. The quality of obturation [Coll and sadrain, 1996] and presence or absence of voids were evaluated by using Vista scan. The recorded data was statistically analyzed., Results: The highest mean rank value of optimally filled canals was obtained by Group IV [58.00] followed by Group I [50.00] with no significant difference. The highest mean rank value of under filled canals and over filled canals were obtained by Group III and Group II, respectively, and these results were statistically significant. All the four obturation techniques showed presence of voids with no significant difference., Conclusion: Both Lentulo spiral and Past inject carrier were equally efficient in attaining an optimally filled homogenous obturation in deciduous teeth., How to Cite This Article: Raju SS, Reddy RE, Rani TS, et al. Assessment of Four Obturation Methods in Deciduous Teeth Using Digital Radiography: An In Vivo Study. Int J Clin Pediatr Dent 2022;15(S-1):S52-S56., Competing Interests: Source of support: Nil Conflict of interest: None, (Copyright © 2022; The Author(s).)