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Your search keyword '"Pauline E. van Beek"' showing total 3 results
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3 results on '"Pauline E. van Beek"'

1. Opportunities and Challenges of Prognostic Models for Extremely Preterm Infants

Author

Angret de Boer, Pauline E. van Beek, Peter Andriessen, Floris Groenendaal, Marije Hogeveen, Julia S. Meijer, Sylvia A. Obermann-Borst, Wes Onland, Liesbeth (H. C. J.) Scheepers, Marijn J. Vermeulen, E. J. T. (Joanne) Verweij, Lien De Proost, and Rosa Geurtzen

Subjects
extremely preterm infant, decision making, prognostic models, Pediatrics, RJ1-570
Abstract

Predicting the short- and long-term outcomes of extremely preterm infants remains a challenge. Multivariable prognostic models might be valuable tools for clinicians, parents, and policymakers for providing accurate outcome estimates. In this perspective, we discuss the opportunities and challenges of using prognostic models in extremely preterm infants at population and individual levels. At a population level, these models could support the development of guidelines for decisions about treatment limits and may support policy processes such as benchmarking and resource allocation. At an individual level, these models may enhance prenatal counselling conversations by considering multiple variables and improving transparency about expected outcomes. Furthermore, they may improve consistency in projections shared with parents. For the development of prognostic models, we discuss important considerations such as predictor and outcome measure selection, clinical impact assessment, and generalizability. Lastly, future recommendations for developing and using prognostic models are suggested. Importantly, the purpose of a prognostic model should be clearly defined, and integrating these models into prenatal counselling requires thoughtful consideration.

Published
2023
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2. Toddler motor performance and intelligence at school age in preterm born children: A longitudinal cohort study

Author

Kim Vermeulen, Pauline E. van Beek, I.E. van der Horst, Victor J.M. Pop, Martine van Dam, Brigitte Vugs, Peter Andriessen, Eindhoven MedTech Innovation Center, Signal Processing Systems, EngD School AP, and School of Med. Physics and Eng. Eindhoven

Subjects
Intelligence Tests, Intelligence, Infant, Newborn, Wechsler Scales, Infant, Obstetrics and Gynecology, Cohort Studies, Motor performance, Performance IQ, Motor Skills, Child, Preschool, Pediatrics, Perinatology and Child Health, Longitudinal, Humans, Female, Longitudinal Studies, Prematurity
Abstract

Background: Current knowledge regarding differences in verbal intelligence scores (VIQ) and performance intelligence scores (PIQ) in preterm born children is limited. As early motor performance may be essential for developing later visual-perceptual and visual-motor skills, early motor performance may be associated with PIQ. Aims: To evaluate whether in preterm born children motor performance at two years was associated with PIQ at eight years. Methods: Single-centre cohort study including 88 children born

Published
2022

3. [Developmental problems in prematures]

Author

Anne M, De Grauw, Pauline E, Van Beek, and Aleid G, Leemhuis

Subjects
Cohort Studies, Risk Factors, Child, Preschool, Infant, Newborn, Humans, Infant, Gestational Age, Infant, Premature, Diseases, Child, Infant, Premature
Abstract

The French EPIPAGE-2 study evaluated a large group of premature born children (24-34 weeks' gestational age (GA))) at age 5.5 years. Outcome information of the whole cohort was presented after careful imputation including/using the variable socio-economic-status (SES), because participation rate improved with increasing SES. Survival improved with increasing GA. Survival without moderate or severe impairment was 20% in children born at 24-26 weeks' GA, but among the survivors 75% had no or mild impairment. Mild cognitive impairment rates were comparable and common among all GA groups (25-28%) and thus frequent in prematures. School problems were also common. In addition to prematurity, SES is an important risk factor for developmental impairment. Follow-up programs for premature infants beyond 30 weeks' GA are less common and may need extra attention in low SES families. Future studies should focus on both prevention of prematurity and programs to improve outcome.

Published
2022

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