26 results on '"Oliver Christ"'
Search Results
2. Mapping or no Mapping: The Influence of Controller Interaction Design in an Immersive Virtual Reality Tutorial in Two Different Age Groups
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Andreas Urech, Pascal Valentin Meier, Stephan Gut, Pascal Duchene, and Oliver Christ
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immersive virtual reality ,controller interaction ,tutorial ,age ,user experience ,Technology ,Science - Abstract
Navigation and interaction in the virtual world will occur via controllers. Previous literature suggests that not all buttons on these controllers are suitable for all functions and that unclear or uncomfortable operations can lead to frustration. This study aimed to determine if an operation with freely selectable buttons differs from one with mapped buttons, in which human-factor differences can be identified, and if there are differences between primary and advanced training. A field experiment with professionals employed by Swiss Federal Railways and apprentices and future apprentices (N = 60) was conducted in a VR tutorial that was previously developed using design cues from existing literature. Controller operation was varied in the groups. The results show significant differences and interaction effects, which indicate that a different operation is more appropriate for apprentices than for professionals in further education.
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- 2024
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3. Job relevance or perceived usefulness? What features of immersive virtual reality software predict intention to use in a future project-based-learning scenario: a mixed method approach
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Alessio Travaglini, Esther Brand, Pascal Meier, and Oliver Christ
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immersive virtual reality applications ,project-based learning ,intention to use ,perceived usefulness ,job relevance ,mixed methods ,Electronic computers. Computer science ,QA75.5-76.95 - Abstract
Not only since COVID-19, the topic of decentralized working and learning methods is becoming increasingly important for various reasons. New virtual reality technologies enable learning in immersive scenarios, which is good when learning from home is advised. However, not all immersive Virtual Reality (iVR) training incorporates learning systems that support complex, realistic, practical tasks that lead to a product or enable acquiring knowledge and life-enhancing skills like project-based learning. Although there are many iVR applications available that support project management, the specific features of these applications that lead to the intention to use (and therefore life-enhancing skills) have yet to be discovered. In this exploratory mixed-method study, we investigated the question of the importance of perceived usefulness (PU) and job relevance (JR) as predictors of intention to use (ItU) in a selection of immersive iVR application features. We started with market research and aggregated 88 software features in 13 categories of 34 professional iVR applications. After an expert selection and ranking procedure, a survey was developed. After deriving from the TAM 2 model and with a sample n = 103, we computed the relationship of JR, PU, and ItU. Although high values were generally observed, we found that the importance of PU is higher than JR when it comes to ItU. Limitations of the study are discussed, and suggestions for further research are given.
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- 2023
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4. Warmth and competence perceptions of key protagonists are associated with containment measures during the COVID-19 pandemic: Evidence from 35 countries
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Maria-Therese Friehs, Patrick F. Kotzur, Christine Kraus, Moritz Schemmerling, Jessica A. Herzig, Adrian Stanciu, Sebastian Dilly, Lisa Hellert, Doreen Hübner, Anja Rückwardt, Veruschka Ulizcay, Oliver Christ, Marco Brambilla, Jonas De keersmaecker, Federica Durante, Jessica Gale, Dmitry Grigoryev, Eric R. Igou, Nino Javakhishvili, Doris Kienmoser, Gandalf Nicolas, Julian Oldmeadow, Odile Rohmer, Bjørn Sætrevik, Julien Barbedor, Franco Bastias, Sebastian B. Bjørkheim, Aidos Bolatov, Nazire Duran, Andrej Findor, Friedrich Götz, Sylvie Graf, Anna Hakobjanyan, Georgios Halkias, Camellia Hancheva, Martina Hřebíčková, Matej Hruška, Shenel Husnu, Kamoliddin Kadirov, Narine Khachatryan, Francisco G. Macedo, Ana Makashvili, Maylin Martínez-Muñoz, Eric Mercadante, Luiza Mesesan Schmitz, Andreas Michael, Nozima Mullabaeva, Félix Neto, Joana Neto, Merve Ozturk, Svitlana Paschenko, Agnieszka Pietraszkiewicz, Charis Psaltis, Yuting Qiu, Mirjana Rupar, Adil Samekin, Katharina Schmid, Sabine Sczesny, Yiwen Sun, Annika M. Svedholm-Häkkinen, Aleksandra Szymkow, Enoch Teye-Kwadjo, Claudio V. Torres, Luc Vieira, Illia Yahiiaiev, and Vincent Yzerbyt
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Medicine ,Science - Abstract
Abstract It is crucial to understand why people comply with measures to contain viruses and their effects during pandemics. We provide evidence from 35 countries (N total = 12,553) from 6 continents during the COVID-19 pandemic (between 2021 and 2022) obtained via cross-sectional surveys that the social perception of key protagonists on two basic dimensions—warmth and competence—plays a crucial role in shaping pandemic-related behaviors. Firstly, when asked in an open question format, heads of state, physicians, and protest movements were universally identified as key protagonists across countries. Secondly, multiple-group confirmatory factor analyses revealed that warmth and competence perceptions of these and other protagonists differed significantly within and between countries. Thirdly, internal meta-analyses showed that warmth and competence perceptions of heads of state, physicians, and protest movements were associated with support and opposition intentions, containment and prevention behaviors, as well as vaccination uptake. Our results have important implications for designing effective interventions to motivate desirable health outcomes and coping with future health crises and other global challenges.
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- 2022
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5. Author Correction: Warmth and competence perceptions of key protagonists are associated with containment measures during the COVID-19 pandemic: Evidence from 35 countries
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Maria-Therese Friehs, Patrick F. Kotzur, Christine Kraus, Moritz Schemmerling, Jessica A. Herzig, Adrian Stanciu, Sebastian Dilly, Lisa Hellert, Doreen Hübner, Anja Rückwardt, Veruschka Ulizcay, Oliver Christ, Marco Brambilla, Jonas De keersmaecker, Federica Durante, Jessica Gale, Dmitry Grigoryev, Eric R. Igou, Nino Javakhishvili, Doris Kienmoser, Gandalf Nicolas, Julian Oldmeadow, Odile Rohmer, Bjørn Sætrevik, Julien Barbedor, Franco Bastias, Sebastian B. Bjørkheim, Aidos Bolatov, Nazire Duran, Andrej Findor, Friedrich Götz, Sylvie Graf, Anna Hakobjanyan, Georgios Halkias, Camellia Hancheva, Martina Hřebíčková, Matej Hruška, Shenel Husnu, Kamoliddin Kadirov, Narine Khachatryan, Francisco G. Macedo, Ana Makashvili, Maylin Martínez-Muñoz, Eric Mercadante, Luiza Mesesan Schmitz, Andreas Michael, Nozima Mullabaeva, Félix Neto, Joana Neto, Merve Ozturk, Svitlana Paschenko, Agnieszka Pietraszkiewicz, Charis Psaltis, Yuting Qiu, Mirjana Rupar, Adil Samekin, Katharina Schmid, Sabine Sczesny, Yiwen Sun, Annika M. Svedholm-Häkkinen, Aleksandra Szymkow, Enoch Teye-Kwadjo, Claudio V. Torres, Luc Vieira, Illia Yahiiaiev, and Vincent Yzerbyt
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Medicine ,Science - Published
- 2023
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6. Scoring with Confidence? - Exploring High-confidence Scoring for Saving Manual Grading Effort.
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Marie Bexte, Andrea Horbach, Lena Schützler, Oliver Christ, and Torsten Zesch
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- 2024
7. The dark sides of people analytics: reviewing the perils for organisations and employees.
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Lisa Giermindl, Franz Strich, Oliver Christ, Ulrich Leicht-Deobald, and Abdullah Redzepi
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- 2022
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8. Mikroschadstoffelimination auf kleinen Kläranlagen
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Oliver Christ, Alexander Steck, and Dieter Schreff
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In der Kläranlage Irschenberg wird gegenwärtig der Bau eines Bodenfilters mit Aktivkohleanteil geplant. Dieser kann sich für derartige Anlagen als eine sinnvolle Alternative zu den bisher bekannten Technologien einer vierten Reinigungsstufe erweisen.
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- 2023
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9. Learning statistics with interactive pictures using R Shiny: Generally preferred, but not generally advantageous
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Fang Zhao, Lena Schützler, Oliver Christ, and Robert Gaschler
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Statistics and Probability ,Education - Published
- 2022
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10. Come As You Are – Small Groups in an Online Statistics Course for Highly Heterogeneous Students
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Lena Schützler and Oliver Christ
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General Psychology ,Education - Abstract
Statistics is not the subject most psychology students are feverishly looking forward to. Fears and doubts about its relevance are quite common. This is especially pronounced at our institution, a large distance-teaching university with highly heterogeneous students. We recognized three clusters of students that might need special support: (1) students with fear of statistics, (2) students whose school time was a long time ago, (3) students who already failed the statistics exam. We gave those students the opportunity to participate in small, supervised groups to discuss learning strategies, problems, or fears. Students who did not participate served as a control group. We exploratively evaluated which kind of students were interested, and if the groups affected attitudes towards statistics, general self-efficacy, and exam-related variables. Interest and activity in the groups were low. No unique effect of participation in the groups on attitudes and grades were observable. Students stated that the groups did not help them to deal with the course. If these results prove stable in further studies with an improved design, one might conclude that setting up such small groups is not worth the effort.
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- 2022
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11. Antecedents of positive and negative intergroup contact: Evidence from a diary study
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Francesca Prati, Sarina J. Schaefer, Miles Hewstone, and Oliver Christ
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Social Dominance ,Arts and Humanities (miscellaneous) ,Humans ,Cultural Diversity ,General Medicine ,Authoritarianism ,Minority Groups ,Prejudice ,General Psychology - Abstract
In our current globalised, multicultural world, understanding antecedents of reciprocal interactions between native people and people of immigrant background is a major issue, because intergroup contact plays a crucial role in building inclusive societies. In this vein, using daily diary data, we examined the relation between the number of daily positive and negative interactions of White British majority (N = 744) and Asian British minority people (N = 582) with members of the respective outgroup, with RWA, SDO, perceived ingroup norms, neighbourhood diversity and contextual deprivation. Results showed that for the majority group, ingroup norms in favour of intergroup contact were positively associated with positive intergroup encounters, whereas Right Wing Authoritarianism (RWA) was positively associated with negative intergroup contact. Neighbourhood diversity was positively associated with positive and negative intergroup encounters. Moreover, RWA moderated the relationship between neighbourhood diversity and both positive and negative contact of White British people. For the minority group, ingroup norms were positively associated with positive intergroup contact, and the relationship between ingroup norms and negative contact was moderated by SDO. Overall, different factors affect positive and negative intergroup contact of majority and minority groups. We discuss the implications of the findings for future research and interventions.
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- 2022
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12. Characterization of carbon phases in Yamato 74123 ureilite to constrain the meteorite shock history
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Anna Barbaro, Fabrizio Nestola, Lidia Pittarello, Ludovic Ferrière, Mara Murri, Konstantin D. Litasov, Oliver Christ, Matteo Alvaro, M. Chiara Domeneghetti, Barbaro, A, Nestola, F, Pittarello, L, Ferriere, L, Murri, M, Litasov, K, Christ, O, Alvaro, M, and Chiara Domeneghetti, M
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Geophysics ,diamond ,ureilite meteorite ,Carbon phase ,graphite ,Geochemistry and Petrology ,Carbon phases ,shock ,ureilite meteorites ,impact event - Abstract
The formation and shock history of ureilite meteorites, a relatively abundant type of primitive achondrites, has been debated for decades. For this purpose, the characterization of carbon phases can provide further information on diamond and graphite formation in ureilites, shedding light on the origin and history of this meteorite group. In this work, we present X-ray diffraction and micro-Raman spectroscopy analyses performed on diamond and graphite occurring in the ureilite Yamato 74123 (Y-74123). The results show that nano- and microdiamonds coexist with nanographite aggregates. This, together with the shock-deformation features observed in olivine, such as mosaicism and planar fractures, suggest that diamond grains formed by a shock event (≥15 GPa) on the ureilitic parent body (UPB). Our results on Y-74123 are consistent with those obtained on the NWA 7983 ureilite and further support the hypothesis that the simultaneous formation of nano- and microdiamonds with the assistance of a Fe-Ni melt catalysis may be related to the heterogeneous propagation and local scattering of the shock wave. Graphite geothermometry revealed an average recorded temperature (Tmax) of 1314 °C (±120 °C) in agreement with previously estimated crystallization temperatures reported for graphite in Almahata Sitta ureilite.
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- 2022
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13. Intergroup contact is reliably associated with reduced prejudice, even in the face of group threat and discrimination
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Jasper Van Assche, Hermann Swart, Katharina Schmid, Kristof Dhont, Ananthi Al Ramiah, Oliver Christ, Mathias Kauff, Sebastiaan Rothmann, Michael Savelkoul, Nicole Tausch, Ralf Wölfer, Sarah Zahreddine, Muniba Saleem, Miles Hewstone, and University of St Andrews. School of Psychology and Neuroscience
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BF Psychology ,BF ,DAS ,General Medicine ,AC ,Inequality, cohesion and modernization ,Intergroup contact ,MCP ,Discrimination ,Ongelijkheid, cohesie en modernisering ,Intergroup relations ,Threat ,Prejudice ,General Psychology - Abstract
This research was partly supported by a senior postdoctoral research grant from the Research Foundation—Flanders (FWO) awarded to Jasper VanAssche (FWO.3E0.2021.0085.01) under the supervision of Arne Roets. Data collection for the South African studies was supported by the Max Planck Institute for the Study of Religious and Ethnic Diversity, for which the authors thank Steve Vertovec. This research was also funded by grants from the NORFACE ERA NET Plus Migration in Europe program, TheLeverhulme Trust, and the Central Community Relations Unit. Intergroup contact provides a reliable means of reducing prejudice. Yet, critics suggested that its efficacy is undermined, even eliminated, under certain conditions. Specifically, contact may be ineffective in the face of threat, especially to (historically) advantaged groups, and discrimination, experienced especially by (historically) disadvantaged groups. We considered perceived intergroup threat and perceived discrimination as potential moderators of the effect of contact on prejudice. Two meta-analyses of correlational data from 34 studies (totaling 63,945 respondents-drawn from 67 subsamples across 19 countries) showed that contact was associated with decreased prejudice and increased out-group positivity, in cross-sectional and longitudinal designs, among advantaged and disadvantaged group members, and in both Western, Educated, Industrialized, Rich, and Democratic (WEIRD) and non-WEIRD contexts. Both perceived threat and perceived discrimination moderated the contact-attitude association, but in an unanticipated direction. Indeed, contact's beneficial effects were at least as strong among individuals high (r = .19) as among individuals low (r = .18) in perceived threat. Similarly, the effects of contact were at least as strong among those high (r = .23) as among those low (r = .20) in perceived discrimination. We conclude that contact is effective for promoting tolerant societies because it is effective even among subpopulations where achieving that goal might be most challenging. Postprint
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- 2023
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14. Status, relative deprivation, and moral devaluation of immigrants
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Samuel Pehrson, Oliver Christ, Mirona Gheorghiu, and University of St Andrews. School of Psychology and Neuroscience
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anti-immigrant prejudice, group status, moral devaluation, relative deprivation ,Social Psychology ,BF Psychology ,media_common.quotation_subject ,Anti-immigrant prejudice ,Immigration ,Devaluation ,NDAS ,Emigrants and Immigrants ,BF ,Pilot Projects ,Context (language use) ,Entitlement ,Morals ,medicine.disease_cause ,Dehumanization ,Moral devaluatin ,medicine ,Humans ,Relative deprivation ,Prejudice (legal term) ,media_common ,Distrust ,SDG 16 - Peace, Justice and Strong Institutions ,SDG 10 - Reduced Inequalities ,Emigration and Immigration ,Cross-Sectional Studies ,Group status ,Psychology ,Social psychology - Abstract
Immigration has been a prominent political issue for decades, but particularly so with rising national populism. To understand current anti-immigration opinion, we turn to the concept of relative deprivation, which, we argue, is fundamentally about entitlement and is at the heart of popular backlash against immigration. Examining the United Kingdom context, we predicted that immigration attitudes would be contingent on immigrant group status, with immigrants from low-status or poorer countries (Poland, India) more likely to be perceived as encroaching on the majority group’s entitlements than those from high-status or richer countries (Germany, Australia). We further proposed moral devaluation (dehumanization and distrust) as a novel mechanism (over and above prejudice) underlying the conditional effects of relative deprivation on support for formal (anti-immigration policies) and informal (hate crime) means of immigrant exclusion. A pilot study (n = 245) and cross-sectional survey (n = 490) results supported our main prediction that status matters: participants felt more deprived relative to low- than high-status immigrants, and this predicted stronger support for anti-immigration policies both directly and through higher distrust (but not dehumanization). This research highlights the need to unpack the generic ‘immigrant’ category and study anti-immigration sentiment in terms of group status and moral devaluation. Postprint
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- 2022
15. Macro-diversity and Intergroup Attitudes
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Oliver Christ, Katharina Schmid, and Eva G. T. Green
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- 2022
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16. Immersive virtual spacewalking in stakeholder workshops:the effect of immersive, BIM-driven design and interaction tools on human sense of presence
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Oliver Christ, Andreas Papageorgiou, Pascal Meier, Andreas Urech, Andreas Boroch, Melissa Huang, and Christian Eichhorn
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IntroductionOver the last decade, the use of Building Information Modelling (BIM) has become increasingly wide-spread to manage the growing complexity of construction projects. As a result, project managers are facing new challenges in managing stakeholders in BIM projects, as the BIM concept is still relatively new to many of the stakeholders (Leśniak, Górka & Skrzypczak, 2021). The introduction of BIM has brought new and complex activities into the already complex process of project management, resulting in a radical change in the working practices of project managers and in the working practices of the project stakeholders (Li et al., 2021). Besides the purely technical advantages of better(?) planning and manipulating data, plans, etc. used to get the best possible visualization of the future, human factors are at least as, if not more, important when looking into the future. Immersive virtual reality (VR) can transform virtual plans into a walkable world, so that different stakeholders (architect, builder, tenant, etc.) can walk through the same flat without the need for specialist expertise in understanding building plans (Schiavi et al. 2022). This same mental picture of the e. g. apartment can now have an impact on decision-making processes and shorten the time to final judgement. At the same time, different aspects of interior design can be explored (size effect, furnishing, etc.). In our mixed methods study, we wanted to know which interaction mechanisms play an important role in the immersive virtual world and whether the sense of presence (illusion of place) is changed by the virtual design of rooms. MethodsIn three workshops, planned BIM data of two different types of apartments were put into a virtual environment (UNITY3D). We optimized the virtual apartments for an immersive virtual reality walkthrough and developed interactive tools for exploring the virtual apartments. In the first workshop (W1) we aimed to assess and demonstrate the sense of space of the planned apartment. In the second workshop (W2) we focussed on the texturing and in the third workshop we demonstrate the kitchen & wet room variants. Form W1 to W3 the visual details and naturalistic implementation of the virtual apartment were gradually enhanced. The participants were tenants, building owners, architects, and employees from the local building office. Their experience in virtual reality varied from none to a lot of experience. There were different tasks and goals for each workshop. Beside discussions, there was at least one VR-experience session per workshop, where participants would experience the virtual room in groups of two, with tasks specific to the session. This was done with three HTC VIVE pro headsets (one per group) with one per-son experiencing in the virtual world and the other spectating the first-person view from on a 75” screen. After some time, they swapped medium and the person who was in the virtual world now watched from outside. We recorded the following data during the workshop: technical affinity with TA-EG (Karrer, Glaser, Clemens & Bruder, 2009), usability with UEQ-S (Schrepp, Hinderks, Thomaschewski, 2017) and sense of presence with PLBMR (Frank & Kluge, 2014). Additionally, the participants were interviewed several weeks after the workshops with half structured interviews: Over all workshops a dataset of N=13 participants could be archived and evaluated. Descriptive and non-parametric statistics were calculated with SPSS 21. The coding of the interviews was done with MAXQDA.ResultsWe found a heterogeneous group in the scales for technical affinity. Regarding the importance of the tools we found that not all tools were remembered in the interviews. The overall usability rating was good and the most important finding was a significant less sense of presence (PLBMR) in workshop 2 (p > .05, cohens d`=.21).DiscussionThe introduction of BIM resulted in a radical change in the working practices of project managers and in the working practices of the project stakeholders (Li et al., 2021). This change should be carried out in a way that most stakeholders should feel comfortable with. As we saw in the data, the usability ratings were good, but some interviews showed that a reduction in complexity may be a further improvement, since not every feature was remembered or needed in the virtual room (Schiavi et al. 2022). The decrease in sense of presence in the second workshop show a possible connection with the uncanny valley phenomenon. Also, the limitation of the study is discussed and an outlook of possible further research is suggested.
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- 2022
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17. Kundenperspektive: Gestaltung und Messung des Kundennutzens in der Kreislaufwirtschaft
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Michael Hans Gino Kraft, Oliver Christ, and Lukas Scherer
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- 2022
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18. A chondrule formation experiment aboard the ISS: microtomography, scanning electron microscopy and Raman spectroscopy on Mg$_2$SiO$_4$ dust aggregates
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Dominik Spahr, Tamara E. Koch, David Merges, Lkhamsuren Bayarjargal, Philomena-Theresa Genzel, Oliver Christ, Fabian Wilde, Frank E. Brenker, and Björn Winkler
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Geochemistry and Petrology ,ddc:530 ,General Materials Science - Abstract
Physics and chemistry of minerals 49(5), 10 (2022). doi:10.1007/s00269-022-01185-7, We performed an experiment under long-term microgravity conditions aboard the International Space Station (ISS) to obtain information on the energetics and experimental constraints required for the formation of chondrules in the solar nebula by ’nebular lightning’. As a simplified model system, we exposed porous forsterite (Mg$_2$SiO$_4$) dust particles to high-energetic arc discharges. The characterization of the samples after their return by synchrotron microtomography and scanning electron microscopy revealed that aggregates had formed, consisting of several fused Mg$_2$SiO$_4$ particles. The partial melting and fusing of Mg$_2$SiO$_4$ dust particles under microgravity conditions leads to a strong reduction of their porosity. The experimental outcomes vary strongly in their appearance from small spherical melt-droplets (∅≈ 90 µm) to bigger and irregularly shaped aggregates (∅≈ 350 µm). Our results provided new constraints with respect to energetic aspects of chondrule formation and a roadmap for future and more complex experiments on Earth and in microgravity conditions., Published by Springer, Heidelberg
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- 2022
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19. Einleitung: Von der Linearität in die Zirkularität des Wirtschaftens
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Michael Hans Gino Kraft, Oliver Christ, and Lukas Scherer
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- 2022
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20. Shock degree and graphite geothermometry in ureilites NWA 6871 and NWA 3140
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Oliver Christ, Anna Barbaro, Frank E. Brenker, Paolo Nimis, Davide Novella, M. Chiara Domeneghetti, and Fabrizio Nestola
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Geophysics ,Space and Planetary Science - Published
- 2022
21. Branchenperspektive: Analyse und Gestaltung der Wertschöpfungsnetze
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Michael Hans Gino Kraft, Oliver Christ, and Lukas Scherer
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- 2022
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22. Management der Kreislaufwirtschaft : Positionierung und Gestaltung zirkulärer Unternehmen
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Michael Hans Gino Kraft, Oliver Christ, Lukas Scherer, Michael Hans Gino Kraft, Oliver Christ, and Lukas Scherer
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- Industrial organization, Strategic planning, Leadership
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Kreislaufwirtschaft gilt als vielversprechendes Alternativmodell in der Unternehmenspraxis. Zu diesem Zweck beschreiben die Autoren nach einer kurzen Einführung wesentliche Systematiken zur Gestaltung zirkulärer Wertschöpfungsnetzwerke, Wege zur strategischen Positionierung und Ansätze zur Ermittlung des spezifischen Kundennutzens. Das essential bietet einen kompakten Überblick zum Management von Kreislaufunternehmen, in dem die Integration von Good Practices einen hohen praktischen Nutzen verspricht.
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- 2022
23. Leveraging virucidal potential of an anti-microbial coating agent to mitigate fomite transmission of respiratory viruses
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Bommana Chanakya, Kavitha Karunakaran, Oliver Christy Dsa, Anil Prataprai Sanghvi, Chiranjay Mukhopadhyay, and Piya Paul Mudgal
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Adenovirus type 1 ,BARRIER90 ,Enterovirus-coxsackie B1 ,Influenza A (H1N1) ,Quaternary ammonium compounds ,SDG-3 Good health and well-being ,Microbiology ,QR1-502 ,Genetics ,QH426-470 - Abstract
In the wake of the COVID-19 pandemic, respiratory tract infections have emerged as a significant global threat, yet their impact on public health was previously underappreciated. This study investigated the antiviral efficacy of the nano-coating agent BARRIER90, composed of silicon-quaternary ammonium compound and a naturally derived biopolymer, against three distinct respiratory viruses: Influenza A (H1N1), Adenovirus Type 1, and Enterovirus-Coxsackie B1. BARRIER90 exhibited robust and sustained virucidal activity, persisting up to 90 days post-coating, against the enveloped virus, Influenza A, with significant reduction in viral plaques. Contrastingly, its efficacy against non-enveloped viruses revealed transient activity against Enterovirus-Coxsackie B1, with almost no antiviral activity observed against Adenovirus Type 1. These findings indicate the potential of antimicrobial coatings in mitigating viral transmission through contaminated surfaces (fomites), which harbour pathogenic viruses for longer periods. Antimicrobial coatings may facilitate infection control in various settings, including healthcare facilities and shared workspaces.
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- 2024
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24. From cold chain to ambient temperature: transport of viral specimens- a review
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Oliver Christy Dsa, Trupti Sathish Kadni, and Sudheesh N
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Ambient temperature ,inactivation of the virus ,molecular diagnosis ,polymerase chain reaction ,virus transport medium ,Medicine - Abstract
AbstractThe diagnosis of an aetiology is dependent on the collection, transport, and storage of the infectious sample. The transport of the sample plays a crucial role in the chain of diagnosis. It is important to maintain the biological integrity of the pathogen during the transport of the sample to achieve an accurate diagnosis. This is important, particularly for labile organisms like viruses that are inactivated easily compared to other microorganisms. Many transport media have been utilised to ensure the integrity of the virus during transport. While most of the transport media are focused on preserving the infectious properties of the virus, progress has been made to develop virus transport media to inactivate the virus and obtain the stability of the viral nucleic acid, enabling better molecular diagnosis of the virus aetiologies. This review summarises the various media used for the transport of virus samples and focuses on the need to develop virus transport media that inactivates the virus and preserves the viral nucleic acid.
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- 2023
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25. Steering carbon dioxide reduction toward C–C coupling using copper electrodes modified with porous molecular films
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Siqi Zhao, Oliver Christensen, Zhaozong Sun, Hongqing Liang, Alexander Bagger, Kristian Torbensen, Pegah Nazari, Jeppe Vang Lauritsen, Steen Uttrup Pedersen, Jan Rossmeisl, and Kim Daasbjerg
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Science - Abstract
This study explores how the activity and selectivity of Cu electrodes for CO2 reduction can be tuned with organic films of different porosity and thickness. As a result, the films increase the local CO partial pressures and surface coverages.
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- 2023
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26. Justification of Indication for Cranial CT Imaging after Mild Traumatic Brain Injury According to the Current National Guidelines
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Andreas Sakkas, Christel Weiß, Frank Wilde, Marcel Ebeling, Mario Scheurer, Oliver Christian Thiele, Robert Andreas Mischkowski, and Sebastian Pietzka
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intracranial hemorrhage ,computer tomography ,mild traumatic brain injury ,decision rules ,Medicine (General) ,R5-920 - Abstract
The primary aim was to evaluate the compliance of cranial CT indication with the national guideline-based decision rules in patients after mTBI. The secondary aim was to determine the incidence of CT pathologies among justified and unjustified CT scans and to investigate the diagnostic value of these decision rules. This is a retrospective, single-center study on 1837 patients (mean age = 70.7 years) referred to a clinic of oral and maxillofacial surgery following mTBI over a five-year period. The current national clinical decision rules and recommendations for mTBI were retrospectively applied to calculate the incidence of unjustified CT imaging. The intracranial pathologies among the justified and unjustified CT scans were presented using descriptive statistical analysis. The performance of the decision rules was ascertained by calculating the sensitivity, specificity, and predictive values. A total of 123 intracerebral lesions were radiologically detected in 102 (5.5%) of the study patients. Most (62.1%) of the CT scans strictly complied with the guideline recommendations, and 37.8% were not justified and likely avoidable. A significantly higher incidence of intracranial pathology was observed in patients with justified CT scans compared with patients with unjustified CT scans (7.9% vs. 2.5%, p < 0.0001). Patients with loss of consciousness, amnesia, seizures, cephalgia, somnolence, dizziness, nausea, and clinical signs of cranial fractures presented pathologic CT findings more frequently (p < 0.05). The decision rules identified CT pathologies with 92.28% sensitivity and 39.08% specificity. To conclude, compliance with the national decision rules for mTBI was low, and more than a third of the CT scans performed were identified as “likely avoidable”. A higher incidence of pathologic CT findings was detected in patients with justified cranial CT imaging. The investigated decision rules showed a high sensitivity but low specificity for predicting CT pathologies.
- Published
- 2023
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