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30 results on '"Nurieva, Roza"'

1. Distinct molecular and immune hallmarks of inflammatory arthritis induced by immune checkpoint inhibitors for cancer therapy

Author

Kim, Sang T., Chu, Yanshuo, Misoi, Mercy, Suarez-Almazor, Maria E., Tayar, Jean H., Lu, Huifang, Buni, Maryam, Kramer, Jordan, Rodriguez, Emma, Hussain, Zulekha, Neelapu, Sattva S., Wang, Jennifer, Shah, Amishi Y., Tannir, Nizar M., Campbell, Matthew T., Gibbons, Don L., Cascone, Tina, Lu, Charles, Blumenschein, George R., Altan, Mehmet, Lim, Bora, Valero, Vincente, Loghin, Monica E., Tu, Janet, Westin, Shannon N., Naing, Aung, Garcia-Manero, Guillermo, Abdel-Wahab, Noha, Tawbi, Hussein A., Hwu, Patrick, Oliva, Isabella C. Glitza, Davies, Michael A., Patel, Sapna P., Zou, Jun, Futreal, Andrew, Diab, Adi, Wang, Linghua, and Nurieva, Roza

Published
2022
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2. Toxicity in the era of immune checkpoint inhibitor therapy.

Author

Keam, Synat, Turner, Naimah, Kugeratski, Fernanda G., Rico, Rene, Colunga-Minutti, Jocelynn, Poojary, Rayansh, Alekseev, Sayan, Patel, Anisha B., Li, Yuanteng Jeff, Sheshadri, Ajay, Loghin, Monica E., Woodman, Karin, Aaroe, Ashley E., Hamidi, Sarah, Iyer, Priyanka Chandrasekhar, Palaskas, Nicolas L., Yinghong Wang, and Nurieva, Roza

Subjects
IMMUNE checkpoint proteins, CYTOTOXIC T cells, IMMUNE checkpoint inhibitors, ANIMAL models in research, PROGRAMMED cell death 1 receptors
Abstract

Immune checkpoint inhibitors (ICIs) reinvigorate anti-tumor immune responses by disrupting co-inhibitory immune checkpoint molecules such as programmed cell death 1 (PD-1) and cytotoxic T lymphocyte antigen 4 (CTLA-4). Although ICIs have had unprecedented success and have become the standard of care for many cancers, they are often accompanied by off-target inflammation that can occur in any organ system. These immune related adverse events (irAEs) often require steroid use and/or cessation of ICI therapy, which can both lead to cancer progression. Although irAEs are common, the detailed molecular and immune mechanisms underlying their development are still elusive. To further our understanding of irAEs and develop effective treatment options, there is pressing need for preclinical models recapitulating the clinical settings. In this review, we describe current preclinical models and immune implications of ICI-induced skin toxicities, colitis, neurological and endocrine toxicities, pneumonitis, arthritis, and myocarditis along with their management. [ABSTRACT FROM AUTHOR]

Published
2024
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3. Anaplastic transformation in thyroid cancer revealed by single-cell transcriptomics

Author

Lu, Lina, Wang, Jennifer Rui, Henderson, Ying C., Bai, Shanshan, Yang, Jie, Hu, Min, Shiau, Cheng-Kai, Pan, Timothy, Yan, Yuanqing, Tran, Tuan M., Li, Jianzhuo, Kieser, Rachel, Zhao, Xiao, Wang, Jiping, Nurieva, Roza, Williams, Michelle D., Cabanillas, Maria E., Dadu, Ramona, Busaidy, Naifa Lamki, Zafereo, Mark, Navin, Nicholas, Lai, Stephen Y., and Gao, Ruli

Subjects
Thyroid cancer -- Development and progression -- Genetic aspects, Genetic transcription -- Health aspects, Cell transformation -- Genetic aspects -- Health aspects, Health care industry
Abstract

The deadliest anaplastic thyroid cancer (ATC) often transforms from indolent differentiated thyroid cancer (DTC); however, the complex intratumor transformation process is poorly understood. We investigated an anaplastic transformation model by dissecting both cell lineage and cell fate transitions using single-cell transcriptomic and genetic alteration data from patients with different subtypes of thyroid cancer. The resulting spectrum of ATC transformation included stress-responsive DTC cells, inflammatory ATC cells (iATCs), and mitotic-defective ATC cells and extended all the way to mesenchymal ATC cells (mATCs). Furthermore, our analysis identified 2 important milestones: (a) a diploid stage, in which iATC cells were diploids with inflammatory phenotypes and (b) an aneuploid stage, in which mATCs gained aneuploid genomes and mesenchymal phenotypes, producing excessive amounts of collagen and collagen-interacting receptors. In parallel, cancer- associated fibroblasts showed strong interactions among mesenchymal cell types, macrophages shifted from M1 to M2 states, and T cells reprogrammed from cytotoxic to exhausted states, highlighting new therapeutic opportunities for the treatment of ATC., Introduction Anaplastic thyroid cancer (ATC), characterized by an undifferentiated morphology, is arguably one of the most lethal malignancies. According to Surveillance, Epidemiology and End Results (SEER) data (released April 2021) [...]

Published
2023
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4. Emerging therapeutic options for follicular-derived thyroid cancer in the era of immunotherapy

Author

Turner, Naimah, primary, Hamidi, Sarah, additional, Ouni, Rim, additional, Rico, Rene, additional, Henderson, Ying C., additional, Puche, Maria, additional, Alekseev, Sayan, additional, Colunga-Minutti, Jocelynn G., additional, Zafereo, Mark E., additional, Lai, Stephen Y., additional, Kim, Sang T., additional, Cabanillas, Maria E., additional, and Nurieva, Roza, additional

Published
2024
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6. Abstract 3131: Anaplastic transformation model in thyroid cancer revealed by single cell lineage and fate analysis

Author

Lu, Lina, primary, Wang, Jennifer Rui, additional, Henderson, Ying C., additional, Bai, Shanshan, additional, Yang, Jie, additional, Hu, Min, additional, Yan, Yuanqing, additional, Tran, Tuan M, additional, Li, Jianzhuo, additional, Shiau, Cheng-Kai, additional, Kieser, Rachel, additional, Zhao, Xiao, additional, Wang, Jiping, additional, Nurieva, Roza, additional, Williams, Michelle D., additional, Cabanillas, Maria E., additional, Dadu, Ramona, additional, Busaidy, Naifa Lamki, additional, Zafereo, Mark, additional, Navin, Nicholas, additional, Lai, Stephen Y., additional, and Gao, Ruli, additional

Published
2023
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7. Data from IL22 Promotes Kras-Mutant Lung Cancer by Induction of a Protumor Immune Response and Protection of Stemness Properties

Author

Khosravi, Nasim, primary, Caetano, Mauricio S., primary, Cumpian, Amber M., primary, Unver, Nese, primary, De la Garza Ramos, Cynthia, primary, Noble, Oscar, primary, Daliri, Soudabeh, primary, Hernandez, Belinda J., primary, Gutierrez, Berenice A., primary, Evans, Scott E., primary, Hanash, Samir, primary, Alekseev, Andrei M., primary, Yang, Yi, primary, Chang, Seon Hee, primary, Nurieva, Roza, primary, Kadara, Humam, primary, Chen, Jichao, primary, Ostrin, Edwin J., primary, and Moghaddam, Seyed Javad, primary

Published
2023
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8. Supplementary Figures and Table from IL22 Promotes Kras-Mutant Lung Cancer by Induction of a Protumor Immune Response and Protection of Stemness Properties

Author

Khosravi, Nasim, primary, Caetano, Mauricio S., primary, Cumpian, Amber M., primary, Unver, Nese, primary, De la Garza Ramos, Cynthia, primary, Noble, Oscar, primary, Daliri, Soudabeh, primary, Hernandez, Belinda J., primary, Gutierrez, Berenice A., primary, Evans, Scott E., primary, Hanash, Samir, primary, Alekseev, Andrei M., primary, Yang, Yi, primary, Chang, Seon Hee, primary, Nurieva, Roza, primary, Kadara, Humam, primary, Chen, Jichao, primary, Ostrin, Edwin J., primary, and Moghaddam, Seyed Javad, primary

Published
2023
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9. Supplementary Figure 5 from Multifaceted Role of BTLA in the Control of CD8+ T-cell Fate after Antigen Encounter

Author

Ritthipichai, Krit, primary, Haymaker, Cara L., primary, Martinez, Melisa, primary, Aschenbrenner, Andrew, primary, Yi, Xiaohui, primary, Zhang, Minying, primary, Kale, Charuta, primary, Vence, Luis M., primary, Roszik, Jason, primary, Hailemichael, Yared, primary, Overwijk, Willem W., primary, Varadarajan, Navin, primary, Nurieva, Roza, primary, Radvanyi, Laszlo G., primary, Hwu, Patrick, primary, and Bernatchez, Chantale, primary

Published
2023
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10. Supplementary Table 1 from Multifaceted Role of BTLA in the Control of CD8+ T-cell Fate after Antigen Encounter

Author

Ritthipichai, Krit, primary, Haymaker, Cara L., primary, Martinez, Melisa, primary, Aschenbrenner, Andrew, primary, Yi, Xiaohui, primary, Zhang, Minying, primary, Kale, Charuta, primary, Vence, Luis M., primary, Roszik, Jason, primary, Hailemichael, Yared, primary, Overwijk, Willem W., primary, Varadarajan, Navin, primary, Nurieva, Roza, primary, Radvanyi, Laszlo G., primary, Hwu, Patrick, primary, and Bernatchez, Chantale, primary

Published
2023
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11. Supplementary Figure 2 from Multifaceted Role of BTLA in the Control of CD8+ T-cell Fate after Antigen Encounter

Author

Ritthipichai, Krit, primary, Haymaker, Cara L., primary, Martinez, Melisa, primary, Aschenbrenner, Andrew, primary, Yi, Xiaohui, primary, Zhang, Minying, primary, Kale, Charuta, primary, Vence, Luis M., primary, Roszik, Jason, primary, Hailemichael, Yared, primary, Overwijk, Willem W., primary, Varadarajan, Navin, primary, Nurieva, Roza, primary, Radvanyi, Laszlo G., primary, Hwu, Patrick, primary, and Bernatchez, Chantale, primary

Published
2023
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12. Supplementary Table 5 from Multifaceted Role of BTLA in the Control of CD8+ T-cell Fate after Antigen Encounter

Author

Ritthipichai, Krit, primary, Haymaker, Cara L., primary, Martinez, Melisa, primary, Aschenbrenner, Andrew, primary, Yi, Xiaohui, primary, Zhang, Minying, primary, Kale, Charuta, primary, Vence, Luis M., primary, Roszik, Jason, primary, Hailemichael, Yared, primary, Overwijk, Willem W., primary, Varadarajan, Navin, primary, Nurieva, Roza, primary, Radvanyi, Laszlo G., primary, Hwu, Patrick, primary, and Bernatchez, Chantale, primary

Published
2023
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13. Supplementary Table 2 from Multifaceted Role of BTLA in the Control of CD8+ T-cell Fate after Antigen Encounter

Author

Ritthipichai, Krit, primary, Haymaker, Cara L., primary, Martinez, Melisa, primary, Aschenbrenner, Andrew, primary, Yi, Xiaohui, primary, Zhang, Minying, primary, Kale, Charuta, primary, Vence, Luis M., primary, Roszik, Jason, primary, Hailemichael, Yared, primary, Overwijk, Willem W., primary, Varadarajan, Navin, primary, Nurieva, Roza, primary, Radvanyi, Laszlo G., primary, Hwu, Patrick, primary, and Bernatchez, Chantale, primary

Published
2023
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14. Supplementary Table 3 from Multifaceted Role of BTLA in the Control of CD8+ T-cell Fate after Antigen Encounter

Author

Ritthipichai, Krit, primary, Haymaker, Cara L., primary, Martinez, Melisa, primary, Aschenbrenner, Andrew, primary, Yi, Xiaohui, primary, Zhang, Minying, primary, Kale, Charuta, primary, Vence, Luis M., primary, Roszik, Jason, primary, Hailemichael, Yared, primary, Overwijk, Willem W., primary, Varadarajan, Navin, primary, Nurieva, Roza, primary, Radvanyi, Laszlo G., primary, Hwu, Patrick, primary, and Bernatchez, Chantale, primary

Published
2023
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15. Supplementary Table 4 from Multifaceted Role of BTLA in the Control of CD8+ T-cell Fate after Antigen Encounter

Author

Ritthipichai, Krit, primary, Haymaker, Cara L., primary, Martinez, Melisa, primary, Aschenbrenner, Andrew, primary, Yi, Xiaohui, primary, Zhang, Minying, primary, Kale, Charuta, primary, Vence, Luis M., primary, Roszik, Jason, primary, Hailemichael, Yared, primary, Overwijk, Willem W., primary, Varadarajan, Navin, primary, Nurieva, Roza, primary, Radvanyi, Laszlo G., primary, Hwu, Patrick, primary, and Bernatchez, Chantale, primary

Published
2023
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16. Movie 1 from Multifaceted Role of BTLA in the Control of CD8+ T-cell Fate after Antigen Encounter

Author

Ritthipichai, Krit, primary, Haymaker, Cara L., primary, Martinez, Melisa, primary, Aschenbrenner, Andrew, primary, Yi, Xiaohui, primary, Zhang, Minying, primary, Kale, Charuta, primary, Vence, Luis M., primary, Roszik, Jason, primary, Hailemichael, Yared, primary, Overwijk, Willem W., primary, Varadarajan, Navin, primary, Nurieva, Roza, primary, Radvanyi, Laszlo G., primary, Hwu, Patrick, primary, and Bernatchez, Chantale, primary

Published
2023
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17. Movie 2 from Multifaceted Role of BTLA in the Control of CD8+ T-cell Fate after Antigen Encounter

Author

Ritthipichai, Krit, primary, Haymaker, Cara L., primary, Martinez, Melisa, primary, Aschenbrenner, Andrew, primary, Yi, Xiaohui, primary, Zhang, Minying, primary, Kale, Charuta, primary, Vence, Luis M., primary, Roszik, Jason, primary, Hailemichael, Yared, primary, Overwijk, Willem W., primary, Varadarajan, Navin, primary, Nurieva, Roza, primary, Radvanyi, Laszlo G., primary, Hwu, Patrick, primary, and Bernatchez, Chantale, primary

Published
2023
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18. Supplementary Figure 4 from Multifaceted Role of BTLA in the Control of CD8+ T-cell Fate after Antigen Encounter

Author

Ritthipichai, Krit, primary, Haymaker, Cara L., primary, Martinez, Melisa, primary, Aschenbrenner, Andrew, primary, Yi, Xiaohui, primary, Zhang, Minying, primary, Kale, Charuta, primary, Vence, Luis M., primary, Roszik, Jason, primary, Hailemichael, Yared, primary, Overwijk, Willem W., primary, Varadarajan, Navin, primary, Nurieva, Roza, primary, Radvanyi, Laszlo G., primary, Hwu, Patrick, primary, and Bernatchez, Chantale, primary

Published
2023
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19. Supplementary Figure 3 from Multifaceted Role of BTLA in the Control of CD8+ T-cell Fate after Antigen Encounter

Author

Ritthipichai, Krit, primary, Haymaker, Cara L., primary, Martinez, Melisa, primary, Aschenbrenner, Andrew, primary, Yi, Xiaohui, primary, Zhang, Minying, primary, Kale, Charuta, primary, Vence, Luis M., primary, Roszik, Jason, primary, Hailemichael, Yared, primary, Overwijk, Willem W., primary, Varadarajan, Navin, primary, Nurieva, Roza, primary, Radvanyi, Laszlo G., primary, Hwu, Patrick, primary, and Bernatchez, Chantale, primary

Published
2023
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20. Supplementary Figure 1 from Multifaceted Role of BTLA in the Control of CD8+ T-cell Fate after Antigen Encounter

Author

Ritthipichai, Krit, primary, Haymaker, Cara L., primary, Martinez, Melisa, primary, Aschenbrenner, Andrew, primary, Yi, Xiaohui, primary, Zhang, Minying, primary, Kale, Charuta, primary, Vence, Luis M., primary, Roszik, Jason, primary, Hailemichael, Yared, primary, Overwijk, Willem W., primary, Varadarajan, Navin, primary, Nurieva, Roza, primary, Radvanyi, Laszlo G., primary, Hwu, Patrick, primary, and Bernatchez, Chantale, primary

Published
2023
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22. Radiation therapy induces immunosenescence mediated by p90RSK

Author

Imanishi, Masaki, primary, Cheng, Haizi, additional, Kotla, Sivareddy, additional, Deswal, Anita, additional, Le, Nhat-Tu, additional, Chini, Eduardo, additional, Ko, Kyung Ae, additional, Samanthapudi, Venkata S. K., additional, Lee, Ling-Ling, additional, Herrmann, Joerg, additional, Xu, Xiaolei, additional, Reyes-Gibby, Cielito, additional, Yeung, Sai-Ching J., additional, Schadler, Keri L., additional, Yusuf, Syed Wamique, additional, Liao, Zhongxing, additional, Nurieva, Roza, additional, Amir, El-ad David, additional, Burks, Jared K., additional, Palaskas, Nicolas L., additional, Cooke, John P., additional, Lin, Steven H., additional, Kobayashi, Michihiro, additional, Yoshimoto, Momoko, additional, and Abe, Jun-ichi, additional

Published
2022
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23. Treatment-related pulmonary adverse events induced by chemoradiation and Durvalumab affect survival in locally advanced non-small cell lung cancer

Author

Xu, Ting, primary, Wu, Lirong, additional, Gandhi, Saumil, additional, Jing, Wang, additional, Nguyen, Quyhn-Nhu, additional, Chen, Aileen, additional, Chang, Joe Y., additional, Nurieva, Roza, additional, Sheshadri, Ajay, additional, Altan, Mehmet, additional, Lee, Percy P., additional, Lin, Steven H., additional, and Liao, Zhongxing, additional

Published
2022
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25. Abstract 503: Multiparameter Mass Cytometry Reveals The Unique Response Of NaïVe B Cell Cd27 - Subset With The Increase Of T-bet And Cd38 Expression After Radiation Therapy In Thoracic Cancer Patients

Author

Imanishi, Masaki, primary, Cheng, Haizi, additional, Kotla, Sivareddy, additional, Lin, Steven, additional, Deswal, Anita, additional, Ko, Kyung, additional, Samanthapudi, Venkatasubrahman, additional, Le, Nhat-Tu, additional, Fujiwara, Keigi, additional, Liao, Zhongxing, additional, Palaskas, Nicolas L, additional, Yusuf, Syed Wamique, additional, Nurieva, Roza I, additional, Reyes-Gibby, Cielito, additional, Yeung, Sai-Ching, additional, Amir, El-ad David, additional, Burks, Jared K, additional, Kobayashi, Michihiro, additional, Yoshimoto, Momoko, additional, and Abe, Jun-ichi, additional

Published
2022
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26. Interleukin-6 blockade abrogates immunotherapy toxicity and promotes tumor immunity

Author

Hailemichael, Yared, primary, Johnson, Daniel H., additional, Abdel-Wahab, Noha, additional, Foo, Wai Chin, additional, Bentebibel, Salah-Eddine, additional, Daher, May, additional, Haymaker, Cara, additional, Wani, Khalida, additional, Saberian, Chantal, additional, Ogata, Dai, additional, Kim, Sang T., additional, Nurieva, Roza, additional, Lazar, Alexander J., additional, Abu-Sbeih, Hamzah, additional, Fa'ak, Faisal, additional, Mathew, Antony, additional, Wang, Yinghong, additional, Falohun, Adewunmi, additional, Trinh, Van, additional, Zobniw, Chrystia, additional, Spillson, Christine, additional, Burks, Jared K., additional, Awiwi, Muhammad, additional, Elsayes, Khaled, additional, Soto, Luisa Solis, additional, Melendez, Brenda D., additional, Davies, Michael A., additional, Wargo, Jennifer, additional, Curry, Jonathan, additional, Yee, Cassian, additional, Lizee, Gregory, additional, Singh, Shalini, additional, Sharma, Padmanee, additional, Allison, James P., additional, Hwu, Patrick, additional, Ekmekcioglu, Suhendan, additional, and Diab, Adi, additional

Published
2022
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27. Characterization of Altered immunity in Anaplastic Thyroid Cancer

Author

Ouni, Rim, primary, Henderson, Ying, additional, Chen, Yunyun, additional, Turner, Naimah, additional, Padron, William, additional, Dadbin, Ali, additional, McBeath Fujiwara, Elena, additional, Wang, Jennifer R., additional, Cabanillas, Maria, additional, Dadu, Romana, additional, Hofmann, Marie-Claude, additional, Zafereo, Mark E., additional, Kim, Sang Taek, additional, Lai, Stephen, additional, and Nurieva, Roza, additional

Published
2022
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28. Erratum to “Sarcoidosis and Airway Disease After Immune Checkpoint Inhibitor Therapy: Case Study and Review of the Literature” by Soto et al.

Author

Soto, Felipe, Torre-Sada, Luis F., Mott, Frank E., Kim, Sang T., Nurieva, Roza, Nagarajan, Priyadharsini, Guo, Ming, Shannon, Vickie R., Faiz, Saadia A., Casal, Roberto F., Altan, Mehmet, Lin, Julie, and Sheshadri, Ajay

Subjects
SARCOIDOSIS, IMMUNE checkpoint inhibitors
Abstract

This document is a correction notice for an article titled "Sarcoidosis and Airway Disease After Immune Checkpoint Inhibitor Therapy: Case Study and Review of the Literature" by Felipe Soto et al. In the original article, two coauthors were mistakenly excluded from the list of authors. The corrected list of authors is provided in the document. The article was published in the Journal of Immunotherapy & Precision Oncology. [Extracted from the article]

Published
2023
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29. Anaplastic transformation in thyroid cancer revealed by single-cell transcriptomics.

Author

Lina Lu, Rui Wang, Jennifer, Henderson, Ying C., Shanshan Bai, Jie Yang, Min Hu, Cheng-Kai Shiau, Pan, Timothy, Yuanqing Yan, Tran, Tuan M., Jianzhuo Li, Kieser, Rachel, Xiao Zhao, Jiping Wang, Nurieva, Roza, Williams, Michelle D., Cabanillas, Maria E., Dadu, Ramona, Busaidy, Naifa Lamki, and Zafereo, Mark

Abstract

The deadliest anaplastic thyroid cancer (ATC) often transforms from indolent differentiated thyroid cancer (DTC); however, the complex intratumor transformation process is poorly understood. We investigated an anaplastic transformation model by dissecting both cell lineage and cell fate transitions using single-cell transcriptomic and genetic alteration data from patients with different subtypes of thyroid cancer. The resulting spectrum of ATC transformation included stress-responsive DTC cells, inflammatory ATC cells (iATCs), and mitotic-defective ATC cells and extended all the way to mesenchymal ATC cells (mATCs). Furthermore, our analysis identified 2 important milestones: (a) a diploid stage, in which iATC cells were diploids with inflammatory phenotypes and (b) an aneuploid stage, in which mATCs gained aneuploid genomes and mesenchymal phenotypes, producing excessive amounts of collagen and collagen-interacting receptors. In parallel, cancer-associated fibroblasts showed strong interactions among mesenchymal cell types, macrophages shifted from M1 to M2 states, and T cells reprogrammed from cytotoxic to exhausted states, highlighting new therapeutic opportunities for the treatment of ATC. [ABSTRACT FROM AUTHOR]

Published
2023
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30. Author Correction: Distinct molecular and immune hallmarks of inflammatory arthritis induced by immune checkpoint inhibitors for cancer therapy.

Author

Kim ST, Chu Y, Misoi M, Suarez-Almazor ME, Tayar JH, Lu H, Buni M, Kramer J, Rodriguez E, Hussain Z, Neelapu SS, Wang J, Shah AY, Tannir NM, Campbell MT, Gibbons DL, Cascone T, Lu C, Blumenschein GR, Altan M, Lim B, Valero V, Loghin ME, Tu J, Westin SN, Naing A, Garcia-Manero G, Abdel-Wahab N, Tawbi HA, Hwu P, Oliva ICG, Davies MA, Patel SP, Zou J, Futreal A, Diab A, Wang L, and Nurieva R

Published
2024
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