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48 results on '"Noble, G."'

1. Measurements of the Temperature and E-mode Polarization of the Cosmic Microwave Background from the Full 500-square-degree SPTpol Dataset

Author

Chou, T. -L., Ade, P. A. R., Anderson, A. J., Austermann, J. E., Balkenhol, L., Beall, J. A., Bender, A. N., Benson, B. A., Bianchini, F., Bleem, L. E., Carlstrom, J. E., Chang, C. L., Chaubal, P., Chiang, H. C., Citron, R., Moran, C. Corbett, Crawford, T. M., Crites, A. T., de Haan, T., Dobbs, M. A., Dutcher, D., Everett, W., Gallicchio, J., George, E. M., Gupta, N., Halverson, N. W., Holder, G. P., Holzapfel, W. L., Hrubes, J. D., Huang, N., Hubmayr, J., Irwin, K. D., Knox, L., Lee, A. T., Li, D., Lowitz, A., McMahon, J. J., Montgomery, J., Natoli, T., Nibarger, J. P., Noble, G. I., Novosad, V., Omori, Y., Padin, S., Patil, S., Pryke, C., Quan, W., Reichardt, C. L., Ruhl, J. E., Saliwanchik, B. R., Schaffer, K. K., Sievers, C., Smecher, G., Stark, A. A., Tucker, C., Veach, T., Vieira, J. D., Wang, G., Whitehorn, N., Wu, W. L. K., Yefremenko, V., and Zebrowski, J. A.

Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

Using the full four-year SPTpol 500 deg$^2$ dataset in both the 95 GHz and 150 GHz frequency bands, we present measurements of the temperature and $E$-mode polarization of the cosmic microwave background (CMB), as well as the $E$-mode polarization auto-power spectrum ($EE$) and temperature-$E$-mode cross-power spectrum ($TE$) in the angular multipole range $50<\ell<8000$. We find the SPTpol dataset to be self-consistent, passing several internal consistency tests based on maps, frequency bands, bandpowers, and cosmological parameters. The full SPTpol dataset is well-fit by the $\Lambda CDM$ model, for which we find $H_0=70.48\pm2.16$ km s$^{-1}$ Mpc$^{-1}$ and $\Omega_m=0.271\pm0.026$, when using only the SPTpol data and a Planck-based prior on the optical depth to reionization. The $\Lambda CDM$ parameter constraints are consistent across the 95 GHz-only, 150 GHz-only, $TE$-only, and $EE$-only data splits. Between the $\ell<1000$ and $\ell>1000$ data splits, the $\Lambda CDM$ parameter constraints are borderline consistent at the $\sim2\sigma$ level. This consistency improves when including a parameter $A_L$, the degree of lensing of the CMB inferred from the smearing of acoustic peaks. When marginalized over $A_L$, the $\Lambda CDM$ parameter constraints from SPTpol are consistent with those from Planck. The power spectra presented here are the most sensitive measurements of the lensed CMB damping tail to date for roughly $\ell > 1700$ in $TE$ and $\ell > 2000$ in $EE$.

Published
2025

2. Pointing Accuracy Improvements for the South Pole Telescope with Machine Learning

Author

Chichura, P. M., Rahlin, A., Anderson, A. J., Ansarinejad, B., Archipley, M., Balkenhol, L., Benabed, K., Bender, A. N., Benson, B. A., Bianchini, F., Bleem, L. E., Bouchet, F. R., Bryant, L., Camphuis, E., Carlstrom, J. E., Chang, C. L., Chaubal, P., Chokshi, A., Chou, T. -L., Coerver, A., Crawford, T. M., Daley, C., de Haan, T., Dibert, K. R., Dobbs, M. A., Doohan, M., Doussot, A., Dutcher, D., Everett, W., Feng, C., Ferguson, K. R., Fichman, K., Foster, A., Galli, S., Gambrel, A. E., Gardner, R. W., Ge, F., Goeckner-Wald, N., Gualtieri, R., Guidi, F., Guns, S., Halverson, N. W., Hivon, E., Holder, G. P., Holzapfel, W. L., Hood, J. C., Hryciuk, A., Huang, N., Kéruzoré, F., Khalife, A. R., Kim, J., Knox, L., Korman, M., Kornoelje, K., Kuo, C. -L., Levy, K., Lowitz, A. E., Lu, C., Maniyar, A., Marrone, D. P., Martsen, E. S., Menanteau, F., Millea, M., Montgomery, J., Nakato, Y., Natoli, T., Noble, G. I., Omori, Y., Padin, S., Pan, Z., Paschos, P., Phadke, K. A., Pollak, A. W., Prabhu, K., Quan, W., Rahimi, M., Reichardt, C. L., Rouble, M., Ruhl, J. E., Schiappucci, E., Sobrin, J. A., Stark, A. A., Stephen, J., Tandoi, C., Thorne, B., Trendafilova, C., Umilta, C., Veitch-Michaelis, J., Vieira, J. D., Vitrier, A., Wan, Y., Whitehorn, N., Wu, W. L. K., Young, M. R., Zagorski, K., and Zebrowski, J. A.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

We present improvements to the pointing accuracy of the South Pole Telescope (SPT) using machine learning. The ability of the SPT to point accurately at the sky is limited by its structural imperfections, which are impacted by the extreme weather at the South Pole. Pointing accuracy is particularly important during SPT participation in observing campaigns with the Event Horizon Telescope (EHT), which requires stricter accuracy than typical observations with the SPT. We compile a training dataset of historical observations of astronomical sources made with the SPT-3G and EHT receivers on the SPT. We train two XGBoost models to learn a mapping from current weather conditions to two telescope drive control arguments -- one which corrects for errors in azimuth and the other for errors in elevation. Our trained models achieve root mean squared errors on withheld test data of $2.14''$ in cross-elevation and $3.57''$ in elevation, well below our goal of $5''$ along each axis. We deploy our models on the telescope control system and perform further in situ test observations during the EHT observing campaign in 2024 April. Our models result in significantly improved pointing accuracy: for sources within the range of input variables where the models are best trained, average combined pointing error improved 33%, from $15.9''$ to $10.6''$. These improvements, while significant, fall shy of our ultimate goal, but they serve as a proof of concept for the development of future models. Planned upgrades to the EHT receiver on the SPT will necessitate even stricter pointing accuracy which will be achievable with our methods., Comment: 23 pages, 9 figures, to be submitted to Journal of Astronomical Instrumentation (JAI)

Published
2024

3. Multiprobe Cosmology from the Abundance of SPT Clusters and DES Galaxy Clustering and Weak Lensing

Author

Bocquet, S., Grandis, S., Krause, E., To, C., Bleem, L. E., Klein, M., Mohr, J. J., Schrabback, T., Alarcon, A., Alves, O., Amon, A., Andrade-Oliveira, F., Baxter, E. J., Bechtol, K., Becker, M. R., Bernstein, G. M., Blazek, J., Camacho, H., Campos, A., Rosell, A. Carnero, Kind, M. Carrasco, Cawthon, R., Chang, C., Chen, R., Choi, A., Cordero, J., Crocce, M., Davis, C., DeRose, J., Diehl, H. T., Dodelson, S., Doux, C., Drlica-Wagner, A., Eckert, K., Eifler, T. F., Elsner, F., Elvin-Poole, J., Everett, S., Fang, X., Ferté, A., Fosalba, P., Friedrich, O., Frieman, J., Gatti, M., Giannini, G., Gruen, D., Gruendl, R. A., Harrison, I., Hartley, W. G., Herner, K., Huang, H., Huff, E. M., Huterer, D., Jarvis, M., Kuropatkin, N., Leget, P. -F., Lemos, P., Liddle, A. R., MacCrann, N., McCullough, J., Muir, J., Myles, J., Navarro-Alsina, A., Pandey, S., Park, Y., Porredon, A., Prat, J., Raveri, M., Rollins, R. P., Roodman, A., Rosenfeld, R., Rykoff, E. S., Sánchez, C., Sanchez, J., Secco, L. F., Sevilla-Noarbe, I., Sheldon, E., Shin, T., Troxel, M. A., Tutusaus, I., Varga, T. N., Weaverdyck, N., Wechsler, R. H., Wu, H. -Y., Yanny, B., Yin, B., Zhang, Y., Zuntz, J., Abbott, T. M. C., Ade, P. A. R., Aguena, M., Allam, S., Allen, S. W., Anderson, A. J., Ansarinejad, B., Austermann, J. E., Bayliss, M., Beall, J. A., Bender, A. N., Benson, B. A., Bianchini, F., Brodwin, M., Brooks, D., Bryant, L., Burke, D. L., Canning, R. E. A., Carlstrom, J. E., Carretero, J., Castander, F. J., Chang, C. L., Chaubal, P., Chiang, H. C., Chou, T-L., Citron, R., Moran, C. Corbett, Costanzi, M., Crawford, T. M., Crites, A. T., da Costa, L. N., Pereira, M. E. S., Davis, T. M., de Haan, T., Dobbs, M. A., Doel, P., Everett, W., Farahi, A., Flaugher, B., Flores, A. M., Floyd, B., Gallicchio, J., Gaztanaga, E., George, E. M., Gladders, M. D., Gupta, N., Gutierrez, G., Halverson, N. W., Hinton, S. R., Hlavacek-Larrondo, J., Holder, G. P., Hollowood, D. L., Holzapfel, W. L., Hrubes, J. D., Huang, N., Hubmayr, J., Irwin, K. D., James, D. J., Kéruzoré, F., Khullar, G., Kim, K., Knox, L., Kraft, R., Kuehn, K., Lahav, O., Lee, A. T., Lee, S., Li, D., Lidman, C., Lima, M., Lowitz, A., Mahler, G., Mantz, A., Marshall, J. L., McDonald, M., McMahon, J. J., Mena-Fernández, J., Meyer, S. S., Miquel, R., Montgomery, J., Natoli, T., Nibarger, J. P., Noble, G. I., Novosad, V., Ogando, R. L. C., Padin, S., Paschos, P., Patil, S., Malagón, A. A. Plazas, Pryke, C., Reichardt, C. L., Roberson, J., Romer, A. K., Romero, C., Ruhl, J. E., Saliwanchik, B. R., Salvati, L., Samuroff, S., Sanchez, E., Santiago, B., Sarkar, A., Saro, A., Schaffer, K. K., Sharon, K., Sievers, C., Smecher, G., Smith, M., Somboonpanyakul, T., Sommer, M., Stalder, B., Stark, A. A., Stephen, J., Strazzullo, V., Suchyta, E., Swanson, M. E. C., Tarle, G., Thomas, D., Tucker, C., Tucker, D. L., Veach, T., Vieira, J. D., von der Linden, A., Wang, G., Whitehorn, N., Wu, W. L. K., Yefremenko, V., Young, M., Zebrowski, J. A., Zohren, H., Collaboration, DES, and Collaboration, SPT

Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

Cosmic shear, galaxy clustering, and the abundance of massive halos each probe the large-scale structure of the universe in complementary ways. We present cosmological constraints from the joint analysis of the three probes, building on the latest analyses of the lensing-informed abundance of clusters identified by the South Pole Telescope (SPT) and of the auto- and cross-correlation of galaxy position and weak lensing measurements (3$\times$2pt) in the Dark Energy Survey (DES). We consider the cosmological correlation between the different tracers and we account for the systematic uncertainties that are shared between the large-scale lensing correlation functions and the small-scale lensing-based cluster mass calibration. Marginalized over the remaining $\Lambda$CDM parameters (including the sum of neutrino masses) and 52 astrophysical modeling parameters, we measure $\Omega_\mathrm{m}=0.300\pm0.017$ and $\sigma_8=0.797\pm0.026$. Compared to constraints from Planck primary CMB anisotropies, our constraints are only 15% wider with a probability to exceed of 0.22 ($1.2\sigma$) for the two-parameter difference. We further obtain $S_8\equiv\sigma_8(\Omega_\mathrm{m}/0.3)^{0.5}=0.796\pm0.013$ which is lower than the Planck measurement at the $1.6\sigma$ level. The combined SPT cluster, DES 3$\times$2pt, and Planck datasets mildly prefer a non-zero positive neutrino mass, with a 95% upper limit $\sum m_\nu<0.25~\mathrm{eV}$ on the sum of neutrino masses. Assuming a $w$CDM model, we constrain the dark energy equation of state parameter $w=-1.15^{+0.23}_{-0.17}$ and when combining with Planck primary CMB anisotropies, we recover $w=-1.20^{+0.15}_{-0.09}$, a $1.7\sigma$ difference with a cosmological constant. The precision of our results highlights the benefits of multiwavelength multiprobe cosmology., Comment: Submitted to Phys. Rev. D

Published
2024

4. Cosmology From CMB Lensing and Delensed EE Power Spectra Using 2019-2020 SPT-3G Polarization Data

Author

Ge, F., Millea, M., Camphuis, E., Daley, C., Huang, N., Omori, Y., Quan, W., Anderes, E., Anderson, A. J., Ansarinejad, B., Archipley, M., Balkenhol, L., Benabed, K., Bender, A. N., Benson, B. A., Bianchini, F., Bleem, L. E., Bouchet, F. R., Bryant, L., Carlstrom, J. E., Chang, C. L., Chaubal, P., Chen, G., Chichura, P. M., Chokshi, A., Chou, T. -L., Coerver, A., Crawford, T. M., de Haan, T., Dibert, K. R., Dobbs, M. A., Doohan, M., Doussot, A., Dutcher, D., Everett, W., Feng, C., Ferguson, K. R., Fichman, K., Foster, A., Galli, S., Gambrel, A. E., Gardner, R. W., Goeckner-Wald, N., Gualtieri, R., Guidi, F., Guns, S., Halverson, N. W., Hivon, E., Holder, G. P., Holzapfel, W. L., Hood, J. C., Howe, D., Hryciuk, A., Kéruzoré, F., Khalife, A. R., Knox, L., Korman, M., Kornoelje, K., Kuo, C. -L., Lee, A. T., Levy, K., Lowitz, A. E., Lu, C., Maniyar, A., Martsen, E. S., Menanteau, F., Montgomery, J., Nakato, Y., Natoli, T., Noble, G. I., Pan, Z., Paschos, P., Phadke, K. A., Pollak, A. W., Prabhu, K., Rahimi, M., Rahlin, A., Reichardt, C. L., Riebel, D., Rouble, M., Ruhl, J. E., Schiappucci, E., Sobrin, J. A., Stark, A. A., Stephen, J., Tandoi, C., Thorne, B., Trendafilova, C., Umilta, C., Vieira, J. D., Vitrier, A., Wan, Y., Whitehorn, N., Wu, W. L. K., Young, M. R., and Zebrowski, J. A.

Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

From CMB polarization data alone we reconstruct the CMB lensing power spectrum, comparable in overall constraining power to previous temperature-based reconstructions, and an unlensed E-mode power spectrum. The observations, taken in 2019 and 2020 with the South Pole Telescope (SPT) and the SPT-3G camera, cover 1500 deg$^2$ at 95, 150, and 220 GHz with arcminute resolution and roughly 4.9$\mu$K-arcmin coadded noise in polarization. The power spectrum estimates, together with systematic parameter estimates and a joint covariance matrix, follow from a Bayesian analysis using the Marginal Unbiased Score Expansion (MUSE) method. The E-mode spectrum at $\ell>2000$ and lensing spectrum at $L>350$ are the most precise to date. Assuming the $\Lambda$CDM model, and using only these SPT data and priors on $\tau$ and absolute calibration from Planck, we find $H_0=66.81\pm0.81$ km/s/Mpc, comparable in precision to the Planck determination and in 5.4$\sigma$ tension with the most precise $H_0$ inference derived via the distance ladder. We also find $S_8=0.850\pm0.017$, providing further independent evidence of a slight tension with low-redshift structure probes. The $\Lambda$CDM model provides a good simultaneous fit to the combined Planck, ACT, and SPT data, and thus passes a powerful test. Combining these CMB datasets with BAO observations, we find that the effective number of neutrino species, spatial curvature, and primordial helium fraction are consistent with standard model values, and that the 95% confidence upper limit on the neutrino mass sum is 0.075 eV. The SPT data are consistent with the somewhat weak preference for excess lensing power seen in Planck and ACT data relative to predictions of the $\Lambda$CDM model. We also detect at greater than 3$\sigma$ the influence of non-linear evolution in the CMB lensing power spectrum and discuss it in the context of the $S_8$ tension.(abridged), Comment: 28 pages, 21 figures + appendices

Published
2024

5. Detection of Thermal Emission at Millimeter Wavelengths from Low-Earth Orbit Satellites

Author

Foster, A., Chokshi, A., Anderson, A. J., Ansarinejad, B., Archipley, M., Balkenhol, L., Benabed, K., Bender, A. N., Barron, D. R., Benson, B. A., Bianchini, F., Bleem, L. E., Bouchet, F. R., Bryant, L., Camphuis, E., Carlstrom, J. E., Chang, C. L., Chaubal, P., Chichura, P. M., Chou, T. -L., Coerver, A., Crawford, T. M., Daley, C., de Haan, T., Dibert, K. R., Dobbs, M. A., Doussot, A., Dutcher, D., Everett, W., Feng, C., Ferguson, K. R., Fichman, K., Galli, S., Gambrel, A. E., Gardner, R. W., Ge, F., Goeckner-Wald, N., Gualtieri, R., Guidi, F., Guns, S., Halverson, N. W., Hivon, E., Holder, G. P., Holzapfel, W. L., Hood, J. C., Hryciuk, A., Huang, N., Kéruzoré, F., Khalife, A. R., Knox, L., Korman, M., Kornoelje, K., Kuo, C. -L., Levy, K., Lowitz, A. E., Lu, C., Maniyar, A., Martsen, E. S., Menanteau, F., Millea, M., Montgomery, J., Nakato, Y., Natoli, T., Noble, G. I., Omori, Y., Pan, Z., Paschos, P., Phadke, K. A., Pollak, A. W., Prabhu, K., Quan, W., Raghunathan, S., Rahimi, M., Rahlin, A., Reichardt, C. L., Rouble, M., Ruhl, J. E., Schiappucci, E., Sobrin, J. A., Stark, A. A., Stephen, J., Tandoi, C., Thorne, B., Trendafilova, C., Umilta, C., Vieira, J. D., Vitrier, A., Wan, Y., Whitehorn, N., Wu, W. L. K., Young, M. R., and Zebrowski, J. A.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

The detection of satellite thermal emission at millimeter wavelengths is presented using data from the 3rd-Generation receiver on the South Pole Telescope (SPT-3G). This represents the first reported detection of thermal emission from artificial satellites at millimeter wavelengths. Satellite thermal emission is shown to be detectable at high signal-to-noise on timescales as short as a few tens of milliseconds. An algorithm for downloading orbital information and tracking known satellites given observer constraints and time-ordered observatory pointing is described. Consequences for cosmological surveys and short-duration transient searches are discussed, revealing that the integrated thermal emission from all large satellites does not contribute significantly to the SPT-3G survey intensity map. Measured satellite positions are found to be discrepant from their two-line element (TLE) derived ephemerides up to several arcminutes which may present a difficulty in cross-checking or masking satellites from short-duration transient searches.

Published
2024

6. Measurement and Modeling of Polarized Atmosphere at the South Pole with SPT-3G

Author

Coerver, A., Zebrowski, J. A., Takakura, S., Holzapfel, W. L., Ade, P. A. R., Anderson, A. J., Ahmed, Z., Ansarinejad, B., Archipley, M., Balkenhol, L., Barron, D., Benabed, K., Bender, A. N., Benson, B. A., Bianchini, F., Bleem, L. E., Bouchet, F. R., Bryant, L., Camphuis, E., Carlstrom, J. E., Cecil, T. W., Chang, C. L., Chaubal, P., Chichura, P. M., Chokshi, A., Chou, T. -L., Crawford, T. M., Cukierman, A., Daley, C., de Haan, T., Dibert, K. R., Dobbs, M. A., Doussot, A., Dutcher, D., Everett, W., Feng, C., Ferguson, K. R., Fichman, K., Foster, A., Galli, S., Gambrel, A. E., Gardner, R. W., Ge, F., Goeckner-Wald, N., Gualtieri, R., Guidi, F., Guns, S., Halverson, N. W., Hivon, E., Holder, G. P., Hood, J. C., Hryciuk, A., Huang, N., Keruzore, F., Khalife, A. R., Knox, L., Korman, M., Kornoelje, K., Kuo, C. -L., Lee, A. T., Levy, K., Lowitz, A. E., Lu, C., Maniyar, A., Martsen, E. S., Menanteau, F., Millea, M., Montgomery, J., Nakato, Y., Natoli, T., Noble, G. I., Novosad, V., Omori, Y., Padin, S., Pan, Z., Paschos, P., Phadke, K. A., Pollak, A. W., Prabhu, K., Quan, W., Rahimi, M., Rahlin, A., Reichardt, C. L., Rouble, M., Ruhl, J. E., Schiappucci, E., Smecher, G., Sobrin, J. A., Stark, A. A., Stephen, J., Suzuki, A., Tandoi, C., Thompson, K. L., Thorne, B., Trendafilova, C., Tucker, C., Umilta, C., Vieira, J. D., Vitrier, A., Wan, Y., Wang, G., Whitehorn, N., Wu, W. L. K., Yefremenko, V., and Young, M. R.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

We present the detection and characterization of fluctuations in linearly polarized emission from the atmosphere above the South Pole. These measurements make use of Austral winter survey data from the SPT-3G receiver on the South Pole Telescope in three frequency bands centered at 95, 150, and 220 GHz. We use the cross-correlation between detectors to produce an unbiased estimate of the power in Stokes I, Q, and U parameters on large angular scales. Our results are consistent with the polarized signal being produced by the combination of Rayleigh scattering of thermal radiation from the ground and thermal emission from a population of horizontally aligned ice crystals with an anisotropic distribution described by Kolmogorov turbulence. The signal is most significant at large angular scales, high observing frequency, and low elevation angle. Polarized atmospheric emission has the potential to significantly impact observations on the large angular scales being targeted by searches for inflationary B-mode CMB polarization. We present the distribution of measured angular power spectrum amplitudes in Stokes Q and I for 4 years of winter observations, which can be used to simulate the impact of atmospheric polarization and intensity fluctuations at the South Pole on a specified experiment and observation strategy. For the SPT-3G data, downweighting the small fraction of significantly contaminated observations is an effective mitigation strategy. In addition, we present a strategy for further improving sensitivity on large angular scales where maps made in the 220 GHz band are used to measure and subtract the polarized atmosphere signal from the 150 GHz band maps. In observations with the SPT-3G instrument at the South Pole, the polarized atmospheric signal is a well-understood and sub-dominant contribution to the measured noise after implementing the mitigation strategies described here., Comment: 32 pages, 28 figures

Published
2024

8. Mass calibration of DES Year-3 clusters via SPT-3G CMB cluster lensing

Author

Ansarinejad, B., Raghunathan, S., Abbott, T. M. C., Ade, P. A. R., Aguena, M., Alves, O., Anderson, A. J., Andrade-Oliveira, F., Archipley, M., Balkenhol, L., Benabed, K., Bender, A. N., Benson, B. A., Bertin, E., Bianchini, F., Bleem, L. E., Bocquet, S., Bouchet, F. R., Brooks, D., Bryant, L., Burke, D. L., Camphuis, E., Carlstrom, J. E., Rosell, A. Carnero, Carretero, J., Castander, F. J., Cecil, T. W., Chang, C. L., Chaubal, P., Chichura, P. M., Chou, T. -L., Coerver, A., Costanzi, M., Crawford, T. M., Cukierman, A., da Costa, L. N., Daley, C., Davis, T. M., de Haan, T., Desai, S., De Vicente, J., Dibert, K. R., Dobbs, M. A., Doel, P., Doussot, A., Doux, C., Dutcher, D., Everett, W., Feng, C., Ferguson, K. R., Ferrero, I., Fichman, K., Foster, A., Frieman, J., Galli, S., Gambrel, A. E., García-Bellido, J., Gardner, R. W., Gaztanaga, E., Ge, F., Giannini, G., Goeckner-Wald, N., Grandis, S., Gruendl, R. A., Gualtieri, R., Guidi, F., Guns, S., Gutierrez, G., Halverson, N. W., Hinton, S. R., Hivon, E., Holder, G. P., Hollowood, D. L., Holzapfel, W. L., Honscheid, K., Hood, J. C., Huang, N., James, D. J., Kéruzoré, F., Knox, L., Korman, M., Kuo, C. -L., Lee, A. T., Lee, S., Levy, K., Lowitz, A. E., Lu, C., Maniyar, A., Marshall, J. L., Mena-Fernández, J., Menanteau, F., Miquel, R., Millea, M., Mohr, J. J., Montgomery, J., Nakato, Y., Natoli, T., Noble, G. I., Novosad, V., Ogando, R. L. C., Omori, Y., Padin, S., Palmese, A., Pan, Z., Paschos, P., Pereira, M. E. S., Pieres, A., Malagón, A. A. Plazas, Prabhu, K., Quan, W., Rahlin, A., Rahimi, M., Reichardt, C. L., Reil, K., Romer, A. K., Rouble, M., Ruhl, J. E., Sanchez, E., Cid, D. Sanchez, Schiappucci, E., Sevilla-Noarbe, I., Smecher, G., Smith, M., Sobrin, J. A., Stark, A. A., Stephen, J., Suchyta, E., Suzuki, A., Swanson, M. E. C., Tandoi, C., Tarle, G., Thompson, K. L., Thorne, B., Trendafilova, C., Tucker, C., Umilta, C., Vieira, J. D., Wang, G., Weaverdyck, N., Whitehorn, N., Wiseman., P., Wu, W. L. K., Yefremenko, V., Young, M. R., and Zebrowski, J. A.

Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

We measure the stacked lensing signal in the direction of galaxy clusters in the Dark Energy Survey Year 3 (DES Y3) redMaPPer sample, using cosmic microwave background (CMB) temperature data from SPT-3G, the third-generation CMB camera on the South Pole Telescope (SPT). We estimate the lensing signal using temperature maps constructed from the initial 2 years of data from the SPT-3G 'Main' survey, covering 1500 deg$^2$ of the Southern sky. We then use this signal as a proxy for the mean cluster mass of the DES sample. In this work, we employ three versions of the redMaPPer catalogue: a Flux-Limited sample containing 8865 clusters, a Volume-Limited sample with 5391 clusters, and a Volume&Redshift-Limited sample with 4450 clusters. For the three samples, we find the mean cluster masses to be ${M}_{200{\rm{m}}}=1.66\pm0.13$ [stat.]$\pm0.03$ [sys.], $1.97\pm0.18$ [stat.]$\pm0.05$ [sys.], and $2.11\pm0.20$ [stat.]$\pm0.05$ [sys.]$\times{10}^{14}\ {\rm{M}}_{\odot }$, respectively. This is a factor of $\sim2$ improvement relative to the precision of measurements with previous generations of SPT surveys and the most constraining cluster mass measurements using CMB cluster lensing to date. Overall, we find no significant tensions between our results and masses given by redMaPPer mass-richness scaling relations of previous works, which were calibrated using CMB cluster lensing, optical weak lensing, and velocity dispersion measurements from various combinations of DES, SDSS and Planck data. We then divide our sample into 3 redshift and 3 richness bins, finding no significant tensions with optical weak-lensing calibrated masses in these bins. We forecast a $5.7\%$ constraint on the mean cluster mass of the DES Y3 sample with the complete SPT-3G surveys when using both temperature and polarization data and including an additional $\sim1400$ deg$^2$ of observations from the 'Extended' SPT-3G survey., Comment: 23 pages, 9 figures, accepted for publication in JCAP. Minor changes and corrections have been made relative to v1

Published
2024

9. Testing the $\mathbf{\Lambda}$CDM Cosmological Model with Forthcoming Measurements of the Cosmic Microwave Background with SPT-3G

Author

Prabhu, K., Raghunathan, S., Millea, M., Lynch, G., Ade, P. A. R., Anderes, E., Anderson, A. J., Ansarinejad, B., Archipley, M., Balkenhol, L., Benabed, K., Bender, A. N., Benson, B. A., Bianchini, F., Bleem, L. E., Bouchet, F. R., Bryant, L., Camphuis, E., Carlstrom, J. E., Cecil, T. W., Chang, C. L., Chaubal, P., Chichura, P. M., Chou, T. -L., Coerver, A., Crawford, T. M., Cukierman, A., Daley, C., de Haan, T., Dibert, K. R., Dobbs, M. A., Doussot, A., Dutcher, D., Everett, W., Feng, C., Ferguson, K. R., Fichman, K., Foster, A., Galli, S., Gambrel, A. E., Gardner, R. W., Ge, F., Goeckner-Wald, N., Gualtieri, R., Guidi, F., Guns, S., Halverson, N. W., Hivon, E., Holder, G. P., Holzapfel, W. L., Hood, J. C., Hryciuk, A., Huang, N., Kéruzoré, F., Knox, L., Korman, M., Kornoelje, K., Kuo, C. -L., Lee, A. T., Levy, K., Lowitz, A. E., Lu, C., Maniyar, A., Menanteau, F., Montgomery, J., Nakato, Y., Natoli, T., Noble, G. I., Novosad, V., Omori, Y., Padin, S., Pan, Z., Paschos, P., Phadke, K. A., Quan, W., Rahimi, M., Rahlin, A., Reichardt, C. L., Rouble, M., Ruhl, J. E., Schiappucci, E., Smecher, G., Sobrin, J. A., Stark, A. A., Stephen, J., Suzuki, A., Tandoi, C., Thompson, K. L., Thorne, B., Trendafilova, C., Tucker, C., Umilta, C., Vitrier, A., Vieira, J. D., Wan, Y., Wang, G., Whitehorn, N., Wu, W. L. K., Yefremenko, V., Young, M. R., and Zebrowski, J. A.

Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

We forecast constraints on cosmological parameters enabled by three surveys conducted with SPT-3G, the third-generation camera on the South Pole Telescope. The surveys cover separate regions of 1500, 2650, and 6000 ${\rm deg}^{2}$ to different depths, in total observing 25% of the sky. These regions will be measured to white noise levels of roughly 2.5, 9, and 12 $\mu{\rm K-arcmin}$, respectively, in CMB temperature units at 150 GHz by the end of 2024. The survey also includes measurements at 95 and 220 GHz, which have noise levels a factor of ~1.2 and 3.5 times higher than 150 GHz, respectively, with each band having a polarization noise level ~$\sqrt{\text{2}}$ times higher than the temperature noise. We use a novel approach to obtain the covariance matrices for jointly and optimally estimated gravitational lensing potential bandpowers and unlensed CMB temperature and polarization bandpowers. We demonstrate the ability to test the $\Lambda{\rm CDM}$ model via the consistency of cosmological parameters constrained independently from SPT-3G and Planck data, and consider the improvement in constraints on $\Lambda{\rm CDM}$ extension parameters from a joint analysis of SPT-3G and Planck data. The $\Lambda{\rm CDM}$ cosmological parameters are typically constrained with uncertainties up to ~2 times smaller with SPT-3G data, compared to Planck, with the two data sets measuring significantly different angular scales and polarization levels, providing additional tests of the standard cosmological model., Comment: 26 pages; 13 figures; Accepted for publication in ApJ; Minor edits have been made

Published
2024

10. First Constraints on the Epoch of Reionization Using the non-Gaussianity of the Kinematic Sunyaev-Zel{'}dovich Effect from the South Pole Telescope and {\it Herschel}-SPIRE Observations

Author

Raghunathan, S., Ade, P. A. R., Anderson, A. J., Ansarinejad, B., Archipley, M., Austermann, J. E., Balkenhol, L., Beall, J. A., Benabed, K., Bender, A. N., Benson, B. A., Bianchini, F., Bleem, L. E., Bock, J., Bouchet, F. R., Bryant, L., Camphuis, E., Carlstrom, J. E., Cecil, T. W., Chang, C. L., Chaubal, P., Chiang, H. C., Chichura, P. M., Chou, T. -L., Citron, R., Coerver, A., Crawford, T. M., Crites, A. T., Cukierman, A., Daley, C., Dibert, K. R., Dobbs, M. A., Doussot, A., Dutcher, D., Everett, W., Feng, C., Ferguson, K. R., Fichman, K., Foster, A., Galli, S., Gallicchio, J., Gambrel, A. E., Gardner, R. W., Ge, F., George, E. M., Goeckner-Wald, N., Gualtieri, R., Guidi, F., Guns, S., Gupta, N., de Haan, T., Halverson, N. W., Hivon, E., Holder, G. P., Holzapfel, W. L., Hood, J. C., Hrubes, J. D., Hryciuk, A., Huang, N., Hubmayr, J., Irwin, K. D., Kéruzoré, F., Khalife, A. R., Knox, L., Korman, M., Kornoelje, K., Kuo, C. -L., Lee, A. T., Levy, K., Li, D., Lowitz, A. E., Lu, C., Maniyar, A., Martsen, E. S., McMahon, J. J., Menanteau, F., Millea, M., Montgomery, J., Moran, C. Corbett, Nakato, Y., Natoli, T., Nibarger, J. P., Noble, G. I., Novosad, V., Omori, Y., Padin, S., Pan, Z., Paschos, P., Patil, S., Phadke, K. A., Prabhu, K., Pryke, C., Quan, W., Rahimi, M., Rahlin, A., Reichardt, C. L., Rouble, M., Ruhl, J. E., Saliwanchik, B. R., Schaffer, K. K., Schiappucci, E., Sievers, C., Smecher, G., Sobrin, J. A., Stark, A. A., Stephen, J., Suzuki, A., Tandoi, C., Thompson, K. L., Thorne, B., Trendafilova, C., Tucker, C., Umilta, C., Veach, T., Vieira, J. D., Viero, M. P., Wan, Y., Wang, G., Whitehorn, N., Wu, W. L. K., Yefremenko, V., Young, M. R., Zebrowski, J. A., and Zemcov, M.

Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

We report results from an analysis aimed at detecting the trispectrum of the kinematic Sunyaev-Zel{'}dovich (kSZ) effect by combining data from the South Pole Telescope (SPT) and {\it Herschel}-SPIRE experiments over a 100 ${\rm deg}^{2}$ field. The SPT observations combine data from the previous and current surveys, namely SPTpol and SPT-3G, to achieve depths of 4.5, 3, and 16 $\mu {\rm K-arcmin}$ in bands centered at 95, 150, and 220 GHz. For SPIRE, we include data from the 600 and 857 GHz bands. We reconstruct the velocity-induced large-scale correlation of the small-scale kSZ signal with a quadratic estimator that uses two cosmic microwave background (CMB) temperature maps, constructed by optimally combining data from all the frequency bands. We reject the null hypothesis of a zero trispectrum at $10.3\sigma$ level. However, the measured trispectrum contains contributions from both the kSZ and other undesired components, such as CMB lensing and astrophysical foregrounds, with kSZ being sub-dominant. We use the \textsc{Agora} simulations to estimate the expected signal from CMB lensing and astrophysical foregrounds. After accounting for the contributions from CMB lensing and foreground signals, we do not detect an excess kSZ-only trispectrum and use this non-detection to set constraints on reionization. By applying a prior based on observations of the Gunn-Peterson trough, we obtain an upper limit on the duration of reionization of $\Delta z_{\rm re, 50} < 4.5$ (95\% C.L). We find these constraints are fairly robust to foregrounds assumptions. This trispectrum measurement is independent of, but consistent with, {\it Planck}'s optical depth measurement. This result is the first constraint on the epoch of reionization using the non-Gaussian nature of the kSZ signal., Comment: 15 pages, 5 figures (3 in main text and 2 in Appendix); Accepted for publication in PRL; Some texts have been moved to Appendix; Minor change in Fig. 2 to include nomalization; Data products and plotting scripts can be downloaded from https://github.com/sriniraghunathan/kSZ_4pt_SPT_SPIRE

Published
2024
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11. Flaring Stars in a Non-targeted mm-wave Survey with SPT-3G

Author

Tandoi, C., Guns, S., Foster, A., Ade, P. A. R., Anderson, A. J., Ansarinejad, B., Archipley, M., Balkenhol, L., Benabed, K., Bender, A. N., Benson, B. A., Bianchini, F., Bleem, L. E., Bouchet, F. R., Bryant, L., Camphuis, E., Carlstrom, J. E., Cecil, T. W., Chang, C. L., Chaubal, P., Chichura, P. M., Chou, T. -L., Coerver, A., Crawford, T. M., Cukierman, A., Daley, C., de Haan, T., Dibert, K. R., Dobbs, M. A., Doussot, A., Dutcher, D., Everett, W., Feng, C., Ferguson, K. R., Fichman, K., Galli, S., Gambrel, A. E., Gardner, R. W., Ge, F., Goeckner-Wald, N., Gualtieri, R., Guidi, F., Halverson, N. W., Hivon, E., Holder, G. P., Holzapfel, W. L., Hood, J. C., Huang, N., Kéruzoré, F., Knox, L., Korman, M., Kornoelje, K., Kuo, C. -L., Lee, A. T., Levy, K., Lowitz, A. E., Lu, C., Maniyar, A., Menanteau, F., Millea, M., Montgomery, J., Moon, Y., Nakato, Y., Natoli, T., Noble, G. I., Novosad, V., Omori, Y., Padin, S., Pan, Z., Paschos, P., Phadke, K. A., Prabhu, K., Qu, Z., Quan, W., Rahimi, M., Rahlin, A., Reichardt, C. L., Reuter, C., Rouble, M., Ruhl, J. E., Schiappucci, E., Smecher, G., Sobrin, J. A., Stark, A. A., Stephen, J., Suzuki, A., Thompson, K. L., Thorne, B., Trendafilova, C., Tucker, C., Umilta, C., Vieira, J. D., Wan, Y., Wang, G., Whitehorn, N., Wu, W. L. K., Yefremenko, V., Young, M. R., and Zebrowski, J. A.

Subjects
Astrophysics - Solar and Stellar Astrophysics, Astrophysics - Astrophysics of Galaxies
Abstract

We present a flare star catalog from four years of non-targeted millimeter-wave survey data from the South Pole Telescope (SPT). The data were taken with the SPT-3G camera and cover a 1500-square-degree region of the sky from $20^{h}40^{m}0^{s}$ to $3^{h}20^{m}0^{s}$ in right ascension and $-42^{\circ}$ to $-70^{\circ}$ in declination. This region was observed on a nearly daily cadence from 2019-2022 and chosen to avoid the plane of the galaxy. A short-duration transient search of this survey yields 111 flaring events from 66 stars, increasing the number of both flaring events and detected flare stars by an order of magnitude from the previous SPT-3G data release. We provide cross-matching to Gaia DR3, as well as matches to X-ray point sources found in the second ROSAT all-sky survey. We have detected flaring stars across the main sequence, from early-type A stars to M dwarfs, as well as a large population of evolved stars. These stars are mostly nearby, spanning 10 to 1000 parsecs in distance. Most of the flare spectral indices are constant or gently rising as a function of frequency at 95/150/220 GHz. The timescale of these events can range from minutes to hours, and the peak $\nu L_{\nu}$ luminosities range from $10^{27}$ to $10^{31}$ erg s$^{-1}$ in the SPT-3G frequency bands.

Published
2024

12. SPT Clusters with DES and HST Weak Lensing. II. Cosmological Constraints from the Abundance of Massive Halos

Author

Bocquet, S., Grandis, S., Bleem, L. E., Klein, M., Mohr, J. J., Schrabback, T., Abbott, T. M. C., Ade, P. A. R., Aguena, M., Alarcon, A., Allam, S., Allen, S. W., Alves, O., Amon, A., Anderson, A. J., Annis, J., Ansarinejad, B., Austermann, J. E., Avila, S., Bacon, D., Bayliss, M., Beall, J. A., Bechtol, K., Becker, M. R., Bender, A. N., Benson, B. A., Bernstein, G. M., Bhargava, S., Bianchini, F., Brodwin, M., Brooks, D., Bryant, L., Campos, A., Canning, R. E. A., Carlstrom, J. E., Rosell, A. Carnero, Kind, M. Carrasco, Carretero, J., Castander, F. J., Cawthon, R., Chang, C. L., Chang, C., Chaubal, P., Chen, R., Chiang, H. C., Choi, A., Chou, T-L., Citron, R., Moran, C. Corbett, Cordero, J., Costanzi, M., Crawford, T. M., Crites, A. T., da Costa, L. N., Pereira, M. E. S., Davis, C., Davis, T. M., DeRose, J., Desai, S., de Haan, T., Diehl, H. T., Dobbs, M. A., Dodelson, S., Doux, C., Drlica-Wagner, A., Eckert, K., Elvin-Poole, J., Everett, S., Everett, W., Ferrero, I., Ferté, A., Flores, A. M., Frieman, J., Gallicchio, J., García-Bellido, J., Gatti, M., George, E. M., Giannini, G., Gladders, M. D., Gruen, D., Gruendl, R. A., Gupta, N., Gutierrez, G., Halverson, N. W., Harrison, I., Hartley, W. G., Herner, K., Hinton, S. R., Holder, G. P., Hollowood, D. L., Holzapfel, W. L., Honscheid, K., Hrubes, J. D., Huang, N., Hubmayr, J., Huff, E. M., Huterer, D., Irwin, K. D., James, D. J., Jarvis, M., Khullar, G., Kim, K., Knox, L., Kraft, R., Krause, E., Kuehn, K., Kuropatkin, N., Kéruzoré, F., Lahav, O., Lee, A. T., Leget, P. -F., Li, D., Lin, H., Lowitz, A., MacCrann, N., Mahler, G., Mantz, A., Marshall, J. L., McCullough, J., McDonald, M., McMahon, J. J., Mena-Fernández, J., Menanteau, F., Meyer, S. S., Miquel, R., Montgomery, J., Myles, J., Natoli, T., Navarro-Alsina, A., Nibarger, J. P., Noble, G. I., Novosad, V., Ogando, R. L. C., Omori, Y., Padin, S., Pandey, S., Paschos, P., Patil, S., Pieres, A., Malagón, A. A. Plazas, Porredon, A., Prat, J., Pryke, C., Raveri, M., Reichardt, C. L., Roberson, J., Rollins, R. P., Romero, C., Roodman, A., Ruhl, J. E., Rykoff, E. S., Saliwanchik, B. R., Salvati, L., Sánchez, C., Sanchez, E., Cid, D. Sanchez, Saro, A., Schaffer, K. K., Secco, L. F., Sevilla-Noarbe, I., Sharon, K., Sheldon, E., Shin, T., Sievers, C., Smecher, G., Smith, M., Somboonpanyakul, T., Sommer, M., Stalder, B., Stark, A. A., Stephen, J., Strazzullo, V., Suchyta, E., Tarle, G., To, C., Troxel, M. A., Tucker, C., Tutusaus, I., Varga, T. N., Veach, T., Vieira, J. D., Vikhlinin, A., von der Linden, A., Wang, G., Weaverdyck, N., Weller, J., Whitehorn, N., Wu, W. L. K., Yanny, B., Yefremenko, V., Yin, B., Young, M., Zebrowski, J. A., Zhang, Y., Zohren, H., and Zuntz, J.

Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

We present cosmological constraints from the abundance of galaxy clusters selected via the thermal Sunyaev-Zel'dovich (SZ) effect in South Pole Telescope (SPT) data with a simultaneous mass calibration using weak gravitational lensing data from the Dark Energy Survey (DES) and the Hubble Space Telescope (HST). The cluster sample is constructed from the combined SPT-SZ, SPTpol ECS, and SPTpol 500d surveys, and comprises 1,005 confirmed clusters in the redshift range $0.25-1.78$ over a total sky area of 5,200 deg$^2$. We use DES Year 3 weak-lensing data for 688 clusters with redshifts $z<0.95$ and HST weak-lensing data for 39 clusters with $0.6

Published
2024

13. Galaxy Clusters Discovered via the Thermal Sunyaev-Zel'dovich Effect in the 500-square-degree SPTpol Survey

Author

Bleem, L. E., Klein, M., Abbott, T. M. C., Ade, P. A. R., Aguena, M., Alves, O., Anderson, A. J., Andrade-Oliveira, F., Ansarinejad, B., Archipley, M., Ashby, M. L. N., Austermann, J. E., Bacon, D., Beall, J. A., Bender, A. N., Benson, B. A., Bianchini, F., Bocquet, S., Brooks, D., Burke, D. L., Calzadilla, M., Carlstrom, J. E., Rosell, A. Carnero, Carretero, J., Chang, C. L., Chaubal, P., Chiang, H. C., Chou, T-L., Citron, R., Moran, C. Corbett, Costanzi, M., Crawford, T. M., Crites, A. T., da Costa, L. N., de Haan, T., De Vicente, J., Desai, S., Dobbs, M. A., Doel, P., Everett, W., Ferrero, I., Flaugher, B., Floyd, B., Friedel, D., Frieman, J., Gallicchio, J., Garc'ia-Bellido, J., Gatti, M., George, E. M., Giannini, G., Grandis, S., Gruen, D., Gruendl, R. A., Gupta, N., Gutierrez, G., Halverson, N. W., Hinton, S. R., Holder, G. P., Hollowood, D. L., Holzapfel, W. L., Honscheid, K., Hrubes, J. D., Huang, N., Hubmayr, J., Irwin, K. D., Mena-Fernández, J., James, D. J., Kéruzoré, F., Knox, L., Kuehn, K., Lahav, O., Lee, A. T., Lee, S., Li, D., Lowitz, A., Marshal, J. L., McDonald, M., McMahon, J. J., Menanteau, F., Meyer, S. S., Miquel, R., Mohr, J. J., Montgomery, J., Myles, J., Natoli, T., Nibarger, J. P., Noble, G. I., Novosad, V., Ogando, R. L. C., Padin, S., Patil, S., Pereira, M. E. S., Pieres, A., Malag'on, A. A. Plazas, Pryke, C., Reichardt, C. L., Rodr'iguez-Monroy, M., Romer, A. K., Ruhl, J. E., Saliwanchik, B. R., Salvati, L., Sanchez, E., Saro, A., Schaffer, K. K., Schrabback, T., Sevilla-Noarbe, I., Sievers, C., Smecher, G., Smith, M., Somboonpanyakul, T., Stalder, B., Stark, A. A., Suchyta, E., Swanson, M. E. C., Tarle, G., To, C., Tucker, C., Veach, T., Vieira, J. D., Vincenzi, M., Wang, G., Weller, J., Whitehorn, N., Wiseman, P., Wu, W. L. K., Yefremenko, V., Zebrowski, J. A., and Zhang, Y.

Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics, Astrophysics - Astrophysics of Galaxies
Abstract

We present a catalog of 689 galaxy cluster candidates detected at significance $\xi>4$ via their thermal Sunyaev-Zel'dovich (SZ) effect signature in 95 and 150 GHz data from the 500-square-degree SPTpol survey. We use optical and infrared data from the Dark Energy Camera and the Wide-field Infrared Survey Explorer (WISE) and \spitzer \ satellites, to confirm 544 of these candidates as clusters with $\sim94\%$ purity. The sample has an approximately redshift-independent mass threshold at redshift $z>0.25$ and spans $1.5 \times 10^{14} < M_{500c} < 9.1 \times 10^{14}$ $M_\odot/h_{70}$ \ and $0.031$. We use external radio data from the Sydney University Molonglo Sky Survey (SUMSS) to estimate contamination to the SZ signal from synchrotron sources. The contamination reduces the recovered $\xi$ by a median value of 0.032, or $\sim0.8\%$ of the $\xi=4$ threshold value, and $\sim7\%$ of candidates have a predicted contamination greater than $\Delta \xi = 1$. With the exception of a small number of systems $(<1\%)$, an analysis of clusters detected in single-frequency 95 and 150 GHz data shows no significant contamination of the SZ signal by emission from dusty or synchrotron sources. This cluster sample will be a key component in upcoming astrophysical and cosmological analyses of clusters. The SPTpol millimeter-wave maps and associated data products used to produce this sample are available at https://pole.uchicago.edu/public/data/sptpol_500d_clusters/index.html, and the NASA LAMBDA website. An interactive sky server with the SPTpol maps and Dark Energy Survey data release 2 images is also available at NCSA https://skyviewer.ncsa.illinois.edu., Comment: Matches version accepted by OJA. 19 pages + references, 14 figures, cluster candidate table provided in Appendix. Data products available at https://pole.uchicago.edu/public/data/sptpol_500d_clusters/index.html and an interactive sky server at https://skyviewer.ncsa.illinois.edu

Published
2023
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14. A Measurement of Gravitational Lensing of the Cosmic Microwave Background Using SPT-3G 2018 Data

Author

Pan, Z., Bianchini, F., Wu, W. L. K., Ade, P. A. R., Ahmed, Z., Anderes, E., Anderson, A. J., Ansarinejad, B., Archipley, M., Aylor, K., Balkenhol, L., Barry, P. S., Thakur, R. Basu, Benabed, K., Bender, A. N., Benson, B. A., Bleem, L. E., Bouchet, F. R., Bryant, L., Byrum, K., Camphuis, E., Carlstrom, J. E., Carter, F. W., Cecil, T. W., Chang, C. L., Chaubal, P., Chen, G., Chichura, P. M., Cho, H. -M., Chou, T. -L., Cliche, J. -F., Coerver, A., Crawford, T. M., Cukierman, A., Daley, C., de Haan, T., Denison, E. V., Dibert, K. R., Ding, J., Dobbs, M. A., Doussot, A., Dutcher, D., Everett, W., Feng, C., Ferguson, K. R., Fichman, K., Foster, A., Fu, J., Galli, S., Gambrel, A. E., Gardner, R. W., Ge, F., Goeckner-Wald, N., Gualtieri, R., Guidi, F., Guns, S., Gupta, N., Halverson, N. W., Harke-Hosemann, A. H., Harrington, N. L., Henning, J. W., Hilton, G. C., Hivon, E., Holder, G. P., Holzapfel, W. L., Hood, J. C., Howe, D., Huang, N., Irwin, K. D., Jeong, O., Jonas, M., Jones, A., Kéruzoré, F., Khaire, T. S., Knox, L., Kofman, A. M., Korman, M., Kubik, D. L., Kuhlmann, S., Kuo, C. -L., Lee, A. T., Leitch, E. M., Levy, K., Lowitz, A. E., Lu, C., Maniyar, A., Menanteau, F., Meyer, S. S., Michalik, D., Millea, M., Montgomery, J., Nadolski, A., Nakato, Y., Natoli, T., Nguyen, H., Noble, G. I., Novosad, V., Omori, Y., Padin, S., Paschos, P., Pearson, J., Posada, C. M., Prabhu, K., Quan, W., Raghunathan, S., Rahimi, M., Rahlin, A., Reichardt, C. L., Riebel, D., Riedel, B., Ruhl, J. E., Sayre, J. T., Schiappucci, E., Shirokoff, E., Smecher, G., Sobrin, J. A., Stark, A. A., Stephen, J., Story, K. T., Suzuki, A., Takakura, S., Tandoi, C., Thompson, K. L., Thorne, B., Trendafilova, C., Tucker, C., Umilta, C., Vale, L. R., Vanderlinde, K., Vieira, J. D., Wang, G., Whitehorn, N., Yefremenko, V., Yoon, K. W., Young, M. R., and Zebrowski, J. A.

Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

We present a measurement of gravitational lensing over 1500 deg$^2$ of the Southern sky using SPT-3G temperature data at 95 and 150 GHz taken in 2018. The lensing amplitude relative to a fiducial Planck 2018 $\Lambda$CDM cosmology is found to be $1.020\pm0.060$, excluding instrumental and astrophysical systematic uncertainties. We conduct extensive systematic and null tests to check the robustness of the lensing measurements, and report a minimum-variance combined lensing power spectrum over angular multipoles of $50

Published
2023
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15. Simultaneous Millimeter-wave, Gamma-ray, and Optical Monitoring of the Blazar PKS 2326-502 During a Flaring State

Author

Hood II, J. C., Simpson, A., McDaniel, A., Foster, A., Ade, P. A. R., Ajello, M., Anderson, A. J., Austermann, J. E., Beall, J. A., Bender, A. N., Benson, B. A., Bianchini, F., Bleem, L. E., Carlstrom, J. E., Chang, C. L., Chaubal, P., Chiang, H. C., Chou, T-L., Citron, R., Moran, C. Corbett, Crawford, T. M., Crites, A. T., de Haan, T., Dobbs, M. A., Everett, W., Gallicchio, J., George, E. M., Gupta, N., Halverson, N. W., Hilton, G. C., Holder, G. P., Holzapfel, W. L., Hrubes, J. D., Huang, N., Hubmayr, J., Irwin, K. D., Knox, L., Lee, A. T., Li, D., Lowitz, A., Madejski, G., Malkan, M., McMahon, J. J., Meyer, S. S., Montgomery, J., Natoli, T., Nibarger, J. P., Noble, G., Novosad, V., Omori, Y., Padin, S., Patil, S., Pryke, C., Reichardt, C. L., Ruhl, J. E., Saliwanchik, B. R., Schaffer, K. K., Sievers, C., Smecher, G., Stark, A. A., Tucker, C., Veach, T., Vieira, J. D., Wang, G., Whitehorn, N., Wu, W. L. K., Yefremenko, V., Zebrowski, J. A., and Zhang, L.

Subjects
Astrophysics - High Energy Astrophysical Phenomena, Astrophysics - Astrophysics of Galaxies
Abstract

Including millimeter-wave (mm-wave) data in multi-wavelength studies of the variability of active galactic nuclei (AGN) can provide insights into AGN physics that are not easily accessible at other wavelengths. We demonstrate in this work the potential of cosmic microwave background (CMB) telescopes to provide long-term, high-cadence mm-wave AGN monitoring over large fractions of sky. We report on a pilot study using data from the SPTpol instrument on the South Pole Telescope (SPT), which was designed to observe the CMB at arcminute and larger angular scales. Between 2013 and 2016, SPTpol was used primarily to observe a single 500 deg^2 field, covering the entire field several times per day with detectors sensitive to radiation in bands centered at 95 and 150 GHz. We use SPT 150 GHz observations to create AGN light curves, and we compare these mm-wave light curves to those at other wavelengths, in particular gamma-ray and optical. In this Letter, we focus on a single source, PKS 2326-502, which has extensive, day-timescale monitoring data in gamma-ray, optical, and now mm-wave between 2013 and 2016. We find PKS 2326-502 to be in a flaring state in the first two years of this monitoring, and we present a search for evidence of correlated variability between mm-wave, optical R band, and gamma-ray observations. This pilot study is paving the way for AGN monitoring with current and upcoming CMB experiments such as SPT-3G, Simons Observatory, and CMB-S4, including multi-wavelength studies with facilities such as VRO-LSST., Comment: 9 pages, 3 figures, accepted to Astrophysical Journal Letters

Published
2023
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16. A Measurement of the CMB Temperature Power Spectrum and Constraints on Cosmology from the SPT-3G 2018 TT/TE/EE Data Set

Author

Balkenhol, L., Dutcher, D., Mancini, A. Spurio, Doussot, A., Benabed, K., Galli, S., Ade, P. A. R., Anderson, A. J., Ansarinejad, B., Archipley, M., Bender, A. N., Benson, B. A., Bianchini, F., Bleem, L. E., Bouchet, F. R., Bryant, L., Camphuis, E., Carlstrom, J. E., Cecil, T. W., Chang, C. L., Chaubal, P., Chichura, P. M., Chou, T. -L., Coerver, A., Crawford, T. M., Cukierman, A., Daley, C., de Haan, T., Dibert, K. R., Dobbs, M. A., Everett, W., Feng, C., Ferguson, K. R., Foster, A., Gambrel, A. E., Gardner, R. W., Goeckner-Wald, N., Gualtieri, R., Guidi, F., Guns, S., Halverson, N. W., Hivon, E., Holder, G. P., Holzapfel, W. L., Hood, J. C., Huang, N., Knox, L., Korman, M., Kuo, C. -L., Lee, A. T., Lowitz, A. E., Lu, C., Millea, M., Montgomery, J., Nakato, Y., Natoli, T., Noble, G. I., Novosad, V., Omori, Y., Padin, S., Pan, Z., Paschos, P., Prabhu, K., Quan, W., Rahimi, M., Rahlin, A., Reichardt, C. L., Rouble, M., Ruhl, J. E., Schiappucci, E., Smecher, G., Sobrin, J. A., Stark, A. A., Stephen, J., Suzuki, A., Tandoi, C., Thompson, K. L., Thorne, B., Tucker, C., Umilta, C., Vieira, J. D., Wang, G., Whitehorn, N., Wu, W. L. K., Yefremenko, V., Young, M. R., and Zebrowski, J. A.

Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

We present a sample-variance-limited measurement of the temperature power spectrum ($TT$) of the cosmic microwave background (CMB) using observations of a $\sim\! 1500 \,\mathrm{deg}^2$ field made by SPT-3G in 2018. We report multifrequency power spectrum measurements at 95, 150, and 220GHz covering the angular multipole range $750 \leq \ell < 3000$. We combine this $TT$ measurement with the published polarization power spectrum measurements from the 2018 observing season and update their associated covariance matrix to complete the SPT-3G 2018 $TT/TE/EE$ data set. This is the first analysis to present cosmological constraints from SPT $TT$, $TE$, and $EE$ power spectrum measurements jointly. We blind the cosmological results and subject the data set to a series of consistency tests at the power spectrum and parameter level. We find excellent agreement between frequencies and spectrum types and our results are robust to the modeling of astrophysical foregrounds. We report results for $\Lambda$CDM and a series of extensions, drawing on the following parameters: the amplitude of the gravitational lensing effect on primary power spectra $A_\mathrm{L}$, the effective number of neutrino species $N_{\mathrm{eff}}$, the primordial helium abundance $Y_{\mathrm{P}}$, and the baryon clumping factor due to primordial magnetic fields $b$. We find that the SPT-3G 2018 $T/TE/EE$ data are well fit by $\Lambda$CDM with a probability-to-exceed of $15\%$. For $\Lambda$CDM, we constrain the expansion rate today to $H_0 = 68.3 \pm 1.5\,\mathrm{km\,s^{-1}\,Mpc^{-1}}$ and the combined structure growth parameter to $S_8 = 0.797 \pm 0.042$. The SPT-based results are effectively independent of Planck, and the cosmological parameter constraints from either data set are within $<1\,\sigma$ of each other. (abridged), Comment: 35 Pages, 17 Figures, 11 Tables

Published
2022
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17. Simultaneous Millimeter-wave, Gamma-Ray, and Optical Monitoring of the Blazar PKS 2326-502 during a Flaring State

Author

Hood, JC, Simpson, A, McDaniel, A, Foster, A, Ade, PAR, Ajello, M, Anderson, AJ, Austermann, JE, Beall, JA, Bender, AN, Benson, BA, Bianchini, F, Bleem, LE, Carlstrom, JE, Chang, CL, Chaubal, P, Chiang, HC, Chou, T-L, Citron, R, Moran, C Corbett, Crawford, TM, Crites, AT, de Haan, T, Dobbs, MA, Everett, W, Gallicchio, J, George, EM, Gupta, N, Halverson, NW, Hilton, GC, Holder, GP, Holzapfel, WL, Hrubes, JD, Huang, N, Hubmayr, J, Irwin, KD, Knox, L, Lee, AT, Li, D, Lowitz, A, Madejski, G, Malkan, M, McMahon, JJ, Meyer, SS, Montgomery, J, Natoli, T, Nibarger, JP, Noble, G, Novosad, V, Omori, Y, Padin, S, Patil, S, Pryke, C, Reichardt, CL, Ruhl, JE, Saliwanchik, BR, Schaffer, KK, Sievers, C, Smecher, G, Stark, AA, Tucker, C, Veach, T, Vieira, JD, Wang, G, Whitehorn, N, Wu, WLK, Yefremenko, V, Zebrowski, JA, and Zhang, L

Subjects
Astronomical and Space Sciences, Astronomy & Astrophysics
Abstract

Abstract Including millimeter-wave data in multiwavelength studies of the variability of active galactic nuclei (AGN) can provide insights into AGN physics that are not easily accessible at other wavelengths. We demonstrate in this work the potential of cosmic microwave background (CMB) telescopes to provide long-term, high-cadence millimeter-wave AGN monitoring over large fractions of sky. We report on a pilot study using data from the SPTpol instrument on the South Pole Telescope (SPT), which was designed to observe the CMB at arcminute and larger angular scales. Between 2013 and 2016, SPTpol was used primarily to observe a single 500 deg2 field, covering the entire field several times per day with detectors sensitive to radiation in bands centered at 95 and 150 GHz. We use SPT 150 GHz observations to create AGN light curves, and we compare these millimeter-wave light curves to those at other wavelengths, in particular γ-ray and optical. In this Letter, we focus on a single source, PKS 2326-502, which has extensive, day-timescale monitoring data in gamma-ray, optical, and now millimeter-wave between 2013 and 2016. We find PKS 2326-502 to be in a flaring state in the first 2 yr of this monitoring, and we present a search for evidence of correlated variability between millimeter-wave, optical R-band, and γ-ray observations. This pilot study is paving the way for AGN monitoring with current and upcoming CMB experiments such as SPT-3G, Simons Observatory, and CMB-S4, including multiwavelength studies with facilities such as Vera C. Rubin Observatories Large Synoptic Survey Telescope.

Published
2023

18. A measurement of the mean central optical depth of galaxy clusters via the pairwise kinematic Sunyaev-Zel'dovich effect with SPT-3G and DES

Author

Schiappucci, E., Bianchini, F., Aguena, M., Archipley, M., Balkenhol, L., Bleem, L. E., Chaubal, P., Crawford, T. M., Grandis, S., Omori, Y., Reichardt, C. L., Rozo, E., Rykoff, E. S., To, C., Abbott, T. M. C., Ade, P. A. R., Alves, O., Anderson, A. J., Andrade-Oliveira, F., Annis, J., Avva, J. S., Bacon, D., Benabed, K., Bender, A. N., Benson, B. A., Bernstein, G. M., Bertin, E., Bocquet, S., Bouchet, F. R., Brooks, D., Burke, D. L., Carlstrom, J. E., Rosell, A. Carnero, Kind, M. Carrasco, Carretero, J., Cecil, T. W., Chang, C. L., Chichura, P. M., Chou, T. -L., Costanzi, M., Cukierman, A., da Costa, L. N., Daley, C., de Haan, T., Desai, S., Dibert, K. R., Diehl, H. T., Dobbs, M. A., Doel, P., Doux, C., Dutcher, D., Everett, S., Everett, W., Feng, C., Ferguson, K. R., Ferrero, I., Ferté, A., Flaugher, B., Foster, A., Frieman, J., Galli, S., Gambrel, A. E., García-Bellido, J., Gardner, R. W., Gatti, M., Giannantonio, T., Goeckner-Wald, N., Gruen, D., Gualtieri, R., Guns, S., Gutierrez, G., Halverson, N. W., Hinton, S. R., Hivon, E., Holder, G. P., Hollowood, D. L., Holzapfel, W. L., Honscheid, K., Hood, J. C., Huang, N., James, D. J., Knox, L., Korman, M., Kuehn, K., Kuo, C. -L., Lahav, O., Lee, A. T., Lidman, C., Lima, M., Lowitz, A. E., Lu, C., March, M., Mena-Fernández, J., Menanteau, F., Millea, M., Miquel, R., Mohr, J. J., Montgomery, J., Muir, J., Natoli, T., Noble, G. I., Novosad, V., Ogando, R. L. C., Padin, S., Pan, Z., Paz-Chinchón, F., Pereira, M. E. S., Pieres, A., Malagón, A. A. Plazas, Prabhu, K., Prat, J., Quan, W., Rahlin, A., Raveri, M., Rodriguez-Monroy, M., Romer, A. K., Rouble, M., Ruhl, J. E., Sanchez, E., Scarpine, V., Schubnell, M., Smecher, G., Smith, M., Soares-Santos, M., Sobrin, J. A., Suchyta, E., Suzuki, A., Tarle, G., Thomas, D., Thompson, K. L., Thorne, B., Tucker, C., Umilta, C., Vieira, J. D., Vincenzi, M., Wang, G., Weaverdyck, N., Weller, J., Whitehorn, N., Wu, W. L. K., Yefremenko, V., and Young, M. R.

Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

We infer the mean optical depth of a sample of optically-selected galaxy clusters from the Dark Energy Survey (DES) via the pairwise kinematic Sunyaev-Zel'dovich (kSZ) effect. The pairwise kSZ signal between pairs of clusters drawn from the DES Year-3 cluster catalog is detected at $4.1 \sigma$ in cosmic microwave background (CMB) temperature maps from two years of observations with the SPT-3G camera on the South Pole Telescope. After cuts, there are 24,580 clusters in the $\sim 1,400$ deg$^2$ of the southern sky observed by both experiments. We infer the mean optical depth of the cluster sample with two techniques. The optical depth inferred from the pairwise kSZ signal is $\bar{\tau}_e = (2.97 \pm 0.73) \times 10^{-3}$, while that inferred from the thermal SZ signal is $\bar{\tau}_e = (2.51 \pm 0.55^{\text{stat}} \pm 0.15^{\rm syst}) \times 10^{-3}$. The two measures agree at $0.6 \sigma$. We perform a suite of systematic checks to test the robustness of the analysis.

Published
2022
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20. Searching for axion-like time-dependent cosmic birefringence with data from SPT-3G

Author

Ferguson, K. R., Anderson, A. J., Whitehorn, N., Ade, P. A. R., Archipley, M., Avva, J. S., Balkenhol, L., Benabed, K., Bender, A. N., Benson, B. A., Bianchini, F., Bleem, L. E., Bouchet, F. R., Bryant, L., Camphuis, E., Carlstrom, J. E., Cecil, T. W., Chang, C. L., Chaubal, P., Chichura, P. M., Chou, T. -L., Crawford, T. M., Cukierman, A., Daley, C., de Haan, T., Dibert, K., Dobbs, M. A., Doussot, A., Dutcher, D., Everett, W., Feng, C., Foster, A., Galli, S., Gambrel, A. E., Gardner, R. W., Goeckner-Wald, N., Gualtieri, R., Guidi, F., Guns, S., Halverson, N. W., Hivon, E., Holder, G. P., Holzapfel, W. L., Hood, J. C., Huang, N., Knox, L., Korman, M., Kuo, C. -L., Lee, A. T., Lowitz, A. E., Lu, C., Millea, M., Montgomery, J., Natoli, T., Noble, G. I., Novosad, V., Omori, Y., Padin, S., Pan, Z., Paschos, P., Prabhu, K., Quan, W., Rahlin, A., Reichardt, C. L., Rouble, M., Ruhl, J. E., Schiappucci, E., Smecher, G., Sobrin, J. A., Stephen, J., Suzuki, A., Tandoi, C., Thompson, K. L., Thorne, B., Tucker, C., Umilta, C., Vieira, J. D., Wang, G., Wu, W. L. K., Yefremenko, V., and Young, M. R.

Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics, High Energy Physics - Experiment
Abstract

Ultralight axionlike particles (ALPs) are compelling dark matter candidates because of their potential to resolve small-scale discrepancies between $\Lambda$CDM predictions and cosmological observations. Axion-photon coupling induces a polarization rotation in linearly polarized photons traveling through an ALP field; thus, as the local ALP dark matter field oscillates in time, distant static polarized sources will appear to oscillate with a frequency proportional to the ALP mass. We use observations of the cosmic microwave background from SPT-3G, the current receiver on the South Pole Telescope, to set upper limits on the value of the axion-photon coupling constant $g_{\phi\gamma}$ over the approximate mass range $10^{-22} - 10^{-19}$ eV, corresponding to oscillation periods from 12 hours to 100 days. For periods between 1 and 100 days ($4.7 \times 10^{-22} \text{ eV} \leq m_\phi \leq 4.7 \times 10^{-20} \text{ eV}$), where the limit is approximately constant, we set a median 95% C.L. upper limit on the amplitude of on-sky polarization rotation of 0.071 deg. Assuming that dark matter comprises a single ALP species with a local dark matter density of $0.3\text{ GeV/cm}^3$, this corresponds to $g_{\phi\gamma} < 1.18 \times 10^{-12}\text{ GeV}^{-1} \times \left( \frac{m_{\phi}}{1.0 \times 10^{-21} \text{ eV}} \right)$. These new limits represent an improvement over the previous strongest limits set using the same effect by a factor of ~3.8., Comment: 16 pages, 5 figures. Accepted for publication in Physical Review D

Published
2022
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21. Asteroid Measurements at Millimeter Wavelengths with the South Pole Telescope

Author

Chichura, P. M., Foster, A., Patel, C., Ossa-Jaen, N., Ade, P. A. R., Ahmed, Z., Anderson, A. J., Archipley, M., Austermann, J. E., Avva, J. S., Balkenhol, L., Barry, P. S., Thakur, R. Basu, Beall, J. A., Benabed, K., Bender, A. N., Benson, B. A., Bianchini, F., Bleem, L. E., Bouchet, F. R., Bryant, L., Byrum, K., Carlstrom, J. E., Carter, F. W., Cecil, T. W., Chang, C. L., Chaubal, P., Chen, G., Chiang, H. C., Cho, H. -M., Chou, T-L., Citron, R., Cliche, J. -F., Crawford, T. M., Crites, A. T., Cukierman, A., Daley, C. M., Denison, E. V., Dibert, K., Ding, J., Dobbs, M. A., Dutcher, D., Everett, W., Feng, C., Ferguson, K. R., Fu, J., Galli, S., Gallicchio, J., Gambrel, A. E., Gardner, R. W., George, E. M., Goeckner-Wald, N., Gualtieri, R., Guns, S., Gupta, N., Guyser, R., de Haan, T., Halverson, N. W., Harke-Hosemann, A. H., Harrington, N. L., Henning, J. W., Hilton, G. C., Hivon, E., Holder, G. P., Holzapfel, W. L., Hood, J. C., Howe, D., Hrubes, J. D., Huang, N., Hubmayr, J., Irwin, K. D., Jeong, O. B., Jonas, M., Jones, A., Khaire, T. S., Knox, L., Kofman, A. M., Korman, M., Kubik, D. L., Kuhlmann, S., Kuo, C. -L., Lee, A. T., Leitch, E. M., Li, D., Lowitz, A., Lu, C., Marrone, D. P., McMahon, J. J., Meyer, S. S., Michalik, D., Millea, M., Mocanu, L. M., Montgomery, J., Moran, C. Corbett, Nadolski, A., Natoli, T., Nguyen, H., Nibarger, J. P., Noble, G., Novosad, V., Omori, Y., Padin, S., Pan, Z., Paschos, P., Patil, S., Pearson, J., Phadke, K. A., Posada, C. M., Prabhu, K., Pryke, C., Quan, W., Rahlin, A., Reichardt, C. L., Riebel, D., Riedel, B., Rouble, M., Ruhl, J. E., Saliwanchik, B. R., Sayre, J. T., Schaffer, K. K., Schiappucci, E., Shirokoff, E., Sievers, C., Smecher, G., Sobrin, J. A., Springmann, A., Stark, A. A., Stephen, J., Story, K. T., Suzuki, A., Tandoi, C., Thompson, K. L., Thorne, B., Tucker, C., Umilta, C., Vale, L. R., Veach, T., Vieira, J. D., Wang, G., Whitehorn, N., Wu, W. L. K., Yefremenko, V., Yoon, K. W., and Young, M. R.

Subjects
Astrophysics - Earth and Planetary Astrophysics
Abstract

We present the first measurements of asteroids in millimeter wavelength (mm) data from the South Pole Telescope (SPT), which is used primarily to study the cosmic microwave background (CMB). We analyze maps of two $\sim270$ deg$^2$ sky regions near the ecliptic plane, each observed with the SPTpol camera $\sim100$ times over one month. We subtract the mean of all maps of a given field, removing static sky signal, and then average the mean-subtracted maps at known asteroid locations. We detect three asteroids$\text{ -- }$(324) Bamberga, (13) Egeria, and (22) Kalliope$\text{ -- }$with signal-to-noise ratios (S/N) of 11.2, 10.4, and 6.1, respectively, at 2.0 mm (150 GHz); we also detect (324) Bamberga with S/N of 4.1 at 3.2 mm (95 GHz). We place constraints on these asteroids' effective emissivities, brightness temperatures, and light curve modulation amplitude. Our flux density measurements of (324) Bamberga and (13) Egeria roughly agree with predictions, while our measurements of (22) Kalliope suggest lower flux, corresponding to effective emissivities of $0.66 \pm 0.11$ at 2.0 mm and $<0.47$ at 3.2mm. We predict the asteroids detectable in other SPT datasets and find good agreement with detections of (772) Tanete and (1093) Freda in recent data from the SPT-3G camera, which has $\sim10 \times$ the mapping speed of SPTpol. This work is the first focused analysis of asteroids in data from CMB surveys, and it demonstrates we can repurpose historic and future datasets for asteroid studies. Future SPT measurements can help constrain the distribution of surface properties over a larger asteroid population., Comment: 21 pages, 9 figures

Published
2022
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26. Measurement of gravitational lensing of the cosmic microwave background using SPT-3G 2018 data

Author

Pan, Z., primary, Bianchini, F., additional, Wu, W. L. K., additional, Ade, P. A. R., additional, Ahmed, Z., additional, Anderes, E., additional, Anderson, A. J., additional, Ansarinejad, B., additional, Archipley, M., additional, Aylor, K., additional, Balkenhol, L., additional, Barry, P. S., additional, Basu Thakur, R., additional, Benabed, K., additional, Bender, A. N., additional, Benson, B. A., additional, Bleem, L. E., additional, Bouchet, F. R., additional, Bryant, L., additional, Byrum, K., additional, Camphuis, E., additional, Carlstrom, J. E., additional, Carter, F. W., additional, Cecil, T. W., additional, Chang, C. L., additional, Chaubal, P., additional, Chen, G., additional, Chichura, P. M., additional, Cho, H.-M., additional, Chou, T.-L., additional, Cliche, J.-F., additional, Coerver, A., additional, Crawford, T. M., additional, Cukierman, A., additional, Daley, C., additional, de Haan, T., additional, Denison, E. V., additional, Dibert, K. R., additional, Ding, J., additional, Dobbs, M. A., additional, Doussot, A., additional, Dutcher, D., additional, Everett, W., additional, Feng, C., additional, Ferguson, K. R., additional, Fichman, K., additional, Foster, A., additional, Fu, J., additional, Galli, S., additional, Gambrel, A. E., additional, Gardner, R. W., additional, Ge, F., additional, Goeckner-Wald, N., additional, Gualtieri, R., additional, Guidi, F., additional, Guns, S., additional, Gupta, N., additional, Halverson, N. W., additional, Harke-Hosemann, A. H., additional, Harrington, N. L., additional, Henning, J. W., additional, Hilton, G. C., additional, Hivon, E., additional, Holder, G. P., additional, Holzapfel, W. L., additional, Hood, J. C., additional, Howe, D., additional, Huang, N., additional, Irwin, K. D., additional, Jeong, O., additional, Jonas, M., additional, Jones, A., additional, Kéruzoré, F., additional, Khaire, T. S., additional, Knox, L., additional, Kofman, A. M., additional, Korman, M., additional, Kubik, D. L., additional, Kuhlmann, S., additional, Kuo, C.-L., additional, Lee, A. T., additional, Leitch, E. M., additional, Levy, K., additional, Lowitz, A. E., additional, Lu, C., additional, Maniyar, A., additional, Menanteau, F., additional, Meyer, S. S., additional, Michalik, D., additional, Millea, M., additional, Montgomery, J., additional, Nadolski, A., additional, Nakato, Y., additional, Natoli, T., additional, Nguyen, H., additional, Noble, G. I., additional, Novosad, V., additional, Omori, Y., additional, Padin, S., additional, Paschos, P., additional, Pearson, J., additional, Posada, C. M., additional, Prabhu, K., additional, Quan, W., additional, Raghunathan, S., additional, Rahimi, M., additional, Rahlin, A., additional, Reichardt, C. L., additional, Riebel, D., additional, Riedel, B., additional, Ruhl, J. E., additional, Sayre, J. T., additional, Schiappucci, E., additional, Shirokoff, E., additional, Smecher, G., additional, Sobrin, J. A., additional, Stark, A. A., additional, Stephen, J., additional, Story, K. T., additional, Suzuki, A., additional, Takakura, S., additional, Tandoi, C., additional, Thompson, K. L., additional, Thorne, B., additional, Trendafilova, C., additional, Tucker, C., additional, Umilta, C., additional, Vale, L. R., additional, Vanderlinde, K., additional, Vieira, J. D., additional, Wang, G., additional, Whitehorn, N., additional, Yefremenko, V., additional, Yoon, K. W., additional, Young, M. R., additional, and Zebrowski, J. A., additional

Published
2023
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27. IT & Data Centre Sustainability in Australia

Author

Noble, G, Atherton, A, Berry, F, Noble, G, Atherton, A, and Berry, F

Abstract

Much of the world’s data is stored, managed, and distributed by data centres on behalf of clients in IT organisations within businesses and public sector organisations. These facilities, both internal and external, and therefore the IT strategists who utilise them, are increasingly exposed to significant environmental, social and governance (ESG) risks that are increasing due to a combination of factors including climate change, digitalisation of economies, geopolitical tensions, and organised crime. The research project seeks to understand awareness amongst Australian sustainability professionals of ESG risks data centres are exposed to, including climate risks. Through an understanding of the constraints and opportunities that these professionals face in implementing sustainability initiatives in the operations of Data centres, actions can be developed to support reducing Data Centre impacts and contributing to Australia’s transition net zero emissions.

Published
2023

28. 3-Methoxytyrosine as an indicator of dopaminergic manipulation in equine plasma.

Author

Keen, B, Cawley, A, Reedy, B, Noble, G, Loy, J, Fu, S, Keen, B, Cawley, A, Reedy, B, Noble, G, Loy, J, and Fu, S

Abstract

The use of catechol-O-methyltransferase inhibitors may mask doping agents, primarily levodopa, administered to racehorses and prolong the stimulating effects of dopaminergic compounds such as dopamine. It is known that 3-methoxytyramine is a metabolite of dopamine and 3-methoxytyrosine is a metabolite of levodopa thus these compounds are proposed to be potential biomarkers of interest. Previous research established a urinary threshold of 4,000 ng/mL for 3-methoxytyramine to monitor misuse of dopaminergic agents. However, there is no equivalent biomarker in plasma. To address this deficiency a rapid protein precipitation method was developed and validated to isolate target compounds from 100 µL equine plasma. A liquid chromatography-high resolution accurate mass (LC-HRAM) method using an IMTAKT Intrada amino acid column provided quantitative analysis of 3-methoxytyrosine (3-MTyr) with lower limit of quantification of 5 ng/mL. Reference population profiling (n = 1129) investigated the expected basal concentrations for raceday samples from equine athletes and showed a right-skewed distribution (skewness = 2.39, kurtosis = 10.65) which resulted from large variation (RSD = 71%) within the data. Logarithmic transformation of the data provided a normal distribution (skewness = 0.26, kurtosis = 3.23) resulting in the proposal of a conservative threshold for plasma 3-MTyr of 1,000 ng/mL at a 99.995% confidence level. A 12-horse administration study of Stalevo® (800 mg L-DOPA, 200 mg carbidopa, 1600 mg entacapone) revealed elevated 3-MTyr concentrations for 24-hours post-administration.

Published
2023

29. Imputed genomes and haplotype-based analyses of the Picts of early medieval Scotland reveal fine-scale relatedness between Iron Age, early medieval and the modern people of the UK

Author

Morez, A., Britton, K., Noble, G., Günther, T., Götherström, A., Rodríguez-Varela, R., Kashuba, N., Martiniano, R., Talamo, S., Evans, N., Irish, J., Donald, C., Girdland-Flink, L., Marchini, J., Mesoudi, A., Olsson, H., Pescetelli, N., Sloman, S., Smaldino, P., and Stein, D.

Subjects
Cancer Research, Archaeology, Genetics, Arkeologi, Molecular Biology, Genetics (clinical), Ecology, Evolution, Behavior and Systematics
Abstract

There are longstanding questions about the origins and ancestry of the Picts of early medieval Scotland (ca. 300-900 CE), prompted in part by exotic medieval origin myths, their enigmatic symbols and inscriptions, and the meagre textual evidence. The Picts, first mentioned in the late 3(rd) century CE resisted the Romans and went on to form a powerful kingdom that ruled over a large territory in northern Britain. In the 9(th) and 10(th) centuries Gaelic language, culture and identity became dominant, transforming the Pictish realm into Alba, the precursor to the medieval kingdom of Scotland. To date, no comprehensive analysis of Pictish genomes has been published, and questions about their biological relationships to other cultural groups living in Britain remain unanswered. Here we present two high-quality Pictish genomes (2.4 and 16.5X coverage) from central and northern Scotland dated from the 5(th)-7(th) century which we impute and co-analyse with >8,300 previously published ancient and modern genomes. Using allele frequency and haplotype-based approaches, we can firmly place the genomes within the Iron Age gene pool in Britain and demonstrate regional biological affinity. We also demonstrate the presence of population structure within Pictish groups, with Orcadian Picts being genetically distinct from their mainland contemporaries. When investigating Identity-By-Descent (IBD) with present-day genomes, we observe broad affinities between the mainland Pictish genomes and the present-day people living in western Scotland, Wales, Northern Ireland and Northumbria, but less with the rest of England, the Orkney islands and eastern Scotland-where the political centres of Pictland were located. The pre-Viking Age Orcadian Picts evidence a high degree of IBD sharing across modern Scotland, Wales, Northern Ireland, and the Orkney islands, demonstrating substantial genetic continuity in Orkney for the last similar to 2,000 years. Analysis of mitochondrial DNA diversity at the Pictish cemetery of Lundin Links (n = 7) reveals absence of direct common female ancestors, with implications for broader social organisation. Overall, our study provides novel insights into the genetic affinities and population structure of the Picts and direct relationships between ancient and present-day groups of the UK. Author summary: We report two high-quality autosomal and eight mitochondrial genomes sequenced from individuals associated with the Pictish period of early medieval Scotland (ca. 300-900 CE). We demonstrate genetic affinities between the Pictish genomes and Iron Age people who lived in Britain, which supports current archaeological theories of a local origin. The autosomal genomes also allowed us to detect haplotype sharing between the Pictish genomes and present-day Europeans. Our results demonstrate a proportionally higher degree of haplotype sharing, and thus genetic affinity, between the Pictish genomes and individuals from western Scotland, Wales, Northern Ireland and Northumbria. We also detected genetic structure in Scotland during the Iron Age, likely driven by the combination of genetic drift and small population size, which we also detect in present-day Orcadians. Lastly, the seven mitochondrial DNA from the Lundin Links cemetery showed that these individuals had no direct maternal ancestors which could suggest exchanges of people, or at least females, between groups during the Pictish period, challenging older ideas that the Picts were a matrilineal society. Overall, our results show that high-quality ancient genomes combined with haplotype imputation are highly informative for obtaining novel insights to population structure and migration over the past 2,000 years.

Published
2023

33. Asteroid Measurements at Millimeter Wavelengths with the South Pole Telescope

Author

Chichura, P. M., primary, Foster, A., additional, Patel, C., additional, Ossa-Jaen, N., additional, Ade, P. A. R., additional, Ahmed, Z., additional, Anderson, A. J., additional, Archipley, M., additional, Austermann, J. E., additional, Avva, J. S., additional, Balkenhol, L., additional, Barry, P. S., additional, Thakur, R. Basu, additional, Beall, J. A., additional, Benabed, K., additional, Bender, A. N., additional, Benson, B. A., additional, Bianchini, F., additional, Bleem, L. E., additional, Bouchet, F. R., additional, Bryant, L., additional, Byrum, K., additional, Carlstrom, J. E., additional, Carter, F. W., additional, Cecil, T. W., additional, Chang, C. L., additional, Chaubal, P., additional, Chen, G., additional, Chiang, H. C., additional, Cho, H.-M., additional, Chou, T-L., additional, Citron, R., additional, Cliche, J.-F., additional, Crawford, T. M., additional, Crites, A. T., additional, Cukierman, A., additional, Daley, C. M., additional, Denison, E. V., additional, Dibert, K., additional, Ding, J., additional, Dobbs, M. A., additional, Dutcher, D., additional, Everett, W., additional, Feng, C., additional, Ferguson, K. R., additional, Fu, J., additional, Galli, S., additional, Gallicchio, J., additional, Gambrel, A. E., additional, Gardner, R. W., additional, George, E. M., additional, Goeckner-Wald, N., additional, Gualtieri, R., additional, Guns, S., additional, Gupta, N., additional, Guyser, R., additional, Haan, T. de, additional, Halverson, N. W., additional, Harke-Hosemann, A. H., additional, Harrington, N. L., additional, Henning, J. W., additional, Hilton, G. C., additional, Hivon, E., additional, Holder, G. P., additional, Holzapfel, W. L., additional, Hood, J. C., additional, Howe, D., additional, Hrubes, J. D., additional, Huang, N., additional, Hubmayr, J., additional, Irwin, K. D., additional, Jeong, O. B., additional, Jonas, M., additional, Jones, A., additional, Khaire, T. S., additional, Knox, L., additional, Kofman, A. M., additional, Korman, M., additional, Kubik, D. L., additional, Kuhlmann, S., additional, Kuo, C.-L., additional, Lee, A. T., additional, Leitch, E. M., additional, Li, D., additional, Lowitz, A., additional, Lu, C., additional, Marrone, D. P., additional, McMahon, J. J., additional, Meyer, S. S., additional, Michalik, D., additional, Millea, M., additional, Mocanu, L. M., additional, Montgomery, J., additional, Moran, C. Corbett, additional, Nadolski, A., additional, Natoli, T., additional, Nguyen, H., additional, Nibarger, J. P., additional, Noble, G., additional, Novosad, V., additional, Omori, Y., additional, Padin, S., additional, Pan, Z., additional, Paschos, P., additional, Patil, S., additional, Pearson, J., additional, Phadke, K. A., additional, Posada, C. M., additional, Prabhu, K., additional, Pryke, C., additional, Quan, W., additional, Rahlin, A., additional, Reichardt, C. L., additional, Riebel, D., additional, Riedel, B., additional, Rouble, M., additional, Ruhl, J. E., additional, Saliwanchik, B. R., additional, Sayre, J. T., additional, Schaffer, K. K., additional, Schiappucci, E., additional, Shirokoff, E., additional, Sievers, C., additional, Smecher, G., additional, Sobrin, J. A., additional, Springmann, A., additional, Stark, A. A., additional, Stephen, J., additional, Story, K. T., additional, Suzuki, A., additional, Tandoi, C., additional, Thompson, K. L., additional, Thorne, B., additional, Tucker, C., additional, Umilta, C., additional, Vale, L. R., additional, Veach, T., additional, Vieira, J. D., additional, Wang, G., additional, Whitehorn, N., additional, Wu, W. L. K., additional, Yefremenko, V., additional, Yoon, K. W., additional, and Young, M. R., additional

Published
2022
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34. Complementary biomarker detection for bisphosphonate use in racehorses

Author

Tou, K, Cawley, A, Bishop, D, Bowen, C, Noble, G, and Fu, S

Subjects
Health, Toxicology and Mutagenesis, Toxicology
Abstract

Aim Determining the use of off-label bisphosphonates (BPs) in young horses ( 4 years old) is of interest due to the threat to racing integrity and welfare associated with this class of drugs that have the potential to manipulate bone structure. The analysis of BPs in biological matrices is challenging by liquid chromatography coupled to mass spectrometry (LC-MS/MS) and alternative sample preparation approaches are needed to detect their misuse in racehorses. There are currently two classes of BPs: non-nitrogen and nitrogen-containing with each having a distinct mode of action. Currently two non-nitrogenous based BPs are available for use in horses, tiludronic acid (or tiludronate) and chlodronate for the treatment of navicular syndrome (Mitchell et al. BMC Veterinary Research 2019;15(1):211) in horses over the age of 4. There is, however, evidence that BPs can persist in the bone for several years after administration since they can form hydroxyapatite crystals prior to being fully absorbed by active osteoclasts where full inhibitory action is performed (Riggs et al. Equine veterinary journal 2021;53(6):1287–1295). Therefore, with this prolonged detection time for the BPs, it is necessary to investigate whether the use of metabolomic biomarkers can provide a complementary method for the detection of their misuse. The aim of this research was to develop a biomarker approach for complementary direct detection of bisphosphonate drugs in equine plasma. Method BPs are hydrophilic therefore the targeted detection of tiludronic acid in equine plasma required an orthogonal solid phase extraction (SPE) method using both a polymeric reversed-phase sorbent and a weak anion exchange cartridge prior to derivatisation using trimethyl orthoacetate and reverse LC-MS/MS. Endogenous lipids and corticosteroids in equine plasma were detected after protein precipitation and SPE with a polymeric reverse phase cartridge prior to liquid chromatography high-resolution mass spectrometry. Da

Published
2022
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35. Searching for axion-like time-dependent cosmic birefringence with SPT-3G

Author

Ferguson, K. R., Anderson, A. J., Whitehorn, N., Ade, P. A. R., Archipley, M., Avva, J. S., Balkenhol, L., Benabed, K., Bender, A. N., Benson, B. A., Bianchini, F., Bleem, L. E., Bouchet, F. R., Camphuis, E., Carlstrom, J. E., Cecil, T. W., Chang, C. L., Chaubal, P., Chichura, P. M., Chou, T. -L., Crawford, T. M., Cukierman, A., Daley, C., de Haan, T., Dibert, K., Dobbs, M. A., Dutcher, D., Everett, W., Feng, C., Foster, A., Galli, S., Gambrel, A. E., Gardner, R. W., Goeckner-Wald, N., Gualtieri, R., Guns, S., Halverson, N. W., Hivon, E., Holder, G. P., Holzapfel, W. L., Hood, J. C., Huang, N., Knox, L., Korman, M., Kuo, C. -L., Lee, A. T., Lowitz, A. E., Lu, C., Millea, M., Montgomery, J., Natoli, T., Noble, G. I., Novosad, V., Omori, Y., Padin, S., Pan, Z., Prabhu, K., Quan, W., Rahlin, A., Reichardt, C. L., Rouble, M., Ruhl, J. E., Schiappucci, E., Smecher, G., Sobrin, J. A., Suzuki, A., Tandoi, C., Thompson, K. L., Thorne, B., Tucker, C., Umilta, C., Vieira, J. D., Wang, G., Wu, W. L. K., Yefremenko, V., Young, M. R., Ferguson, K. R., Anderson, A. J., Whitehorn, N., Ade, P. A. R., Archipley, M., Avva, J. S., Balkenhol, L., Benabed, K., Bender, A. N., Benson, B. A., Bianchini, F., Bleem, L. E., Bouchet, F. R., Camphuis, E., Carlstrom, J. E., Cecil, T. W., Chang, C. L., Chaubal, P., Chichura, P. M., Chou, T. -L., Crawford, T. M., Cukierman, A., Daley, C., de Haan, T., Dibert, K., Dobbs, M. A., Dutcher, D., Everett, W., Feng, C., Foster, A., Galli, S., Gambrel, A. E., Gardner, R. W., Goeckner-Wald, N., Gualtieri, R., Guns, S., Halverson, N. W., Hivon, E., Holder, G. P., Holzapfel, W. L., Hood, J. C., Huang, N., Knox, L., Korman, M., Kuo, C. -L., Lee, A. T., Lowitz, A. E., Lu, C., Millea, M., Montgomery, J., Natoli, T., Noble, G. I., Novosad, V., Omori, Y., Padin, S., Pan, Z., Prabhu, K., Quan, W., Rahlin, A., Reichardt, C. L., Rouble, M., Ruhl, J. E., Schiappucci, E., Smecher, G., Sobrin, J. A., Suzuki, A., Tandoi, C., Thompson, K. L., Thorne, B., Tucker, C., Umilta, C., Vieira, J. D., Wang, G., Wu, W. L. K., Yefremenko, V., and Young, M. R.

Abstract

Ultralight axion-like particles (ALPs) are compelling dark matter candidates because of their potential to resolve small-scale discrepancies between $\Lambda$CDM predictions and cosmological observations. Axion-photon coupling induces a polarization rotation in linearly polarized photons traveling through an ALP field; thus, as the local ALP dark matter field oscillates in time, distant static polarized sources will appear to oscillate with a frequency proportional to the ALP mass. We use observations of the cosmic microwave background from SPT-3G, the current receiver on the South Pole Telescope, to set upper limits on the value of the axion-photon coupling constant $g_{\phi\gamma}$ over the approximate mass range $10^{-22} - 10^{-19}$ eV, corresponding to oscillation periods from 12 hours to 100 days. For periods between 1 and 100 days ($4.7 \times 10^{-22} \text{ eV} \leq m_\phi \leq 4.7 \times 10^{-20} \text{ eV}$), where the limit is approximately constant, we set a median 95% C.L. upper limit on the amplitude of on-sky polarization rotation of 0.071 deg. Assuming that dark matter comprises a single ALP species with a local dark matter density of $0.3 \text{ GeV/cm}^3$, this corresponds to $g_{\phi\gamma} < 1.18 \times 10^{-12}\text{ GeV}^{-1} \times \left( \frac{m_{\phi}}{1.0 \times 10^{-21} \text{ eV}} \right)$. These new limits represent an improvement over the previous strongest limits set using the same effect by a factor of ~3.8., Comment: 16 pages, 5 figures, to be submitted to Physical Review D

Published
2022

36. Performance and characterization of the SPT-3G digital frequency-domain multiplexed readout system using an improved noise and crosstalk model

Author

Montgomery, J, Ade, PAR, Ahmed, Z, Anderes, E, Anderson, AJ, Archipley, MA, Avva, JS, Aylor, K, Balkenhol, L, Barry, PS, Thakur, RB, Benabed, K, Bender, AN, Benson, BA, Bianchini, F, Bleem, LE, Bouchet, FR, Bryant, L, Byrum, K, Carlstrom, JE, Carter, FW, Cecil, TW, Chang, CL, Chaubal, P, Chen, G, Cho, H-M, Chou, T-L, Cliche, J-F, Crawford, TM, Cukierman, AJ, Daley, CM, de Haan, T, Denison, E, Dibert, K, Ding, J, Dobbs, MA, Dutcher, D, Elleflot, T, Everett, WB, Feng, C, Ferguson, KR, Foster, A, Fu, J, Galli, S, Gambrel, AE, Gardner, RW, Goeckner-Wald, N, Groh, JC, Gualtieri, R, Guns, ST, Gupta, N, Guyser, RJ, Halverson, NW, Harke-Hosemann, AH, Harrington, NL, Henning, JW, Hilton, GC, Hivon, EF, Holzapfel, WL, Hood, JC, Howe, D, Huang, N, Irwin, KD, Jeong, OB, Jonas, M, Jones, A, Khaire, TS, Knox, L, Kofman, AM, Korman, M, Kubik, DL, Kuhlmann, SE, Kuo, C-L, Lee, AT, Leitch, EM, Lowitz, AE, Lu, C, Meyer, SS, Michalik, D, Millea, M, Nadolski, A, Natoli, TJ, Nguyen, H, Noble, G, Novosad, V, Omori, Y, Padin, S, Pan, Z, Paschos, P, Pearson, JE, Posada, CM, Prabhu, K, Quan, W, Rahlin, AS, Reichardt, CL, Riebel, D, Riedel, B, Rouble, M, Ruhl, JE, Sayre, JT, Schiappucci, E, Shirokoff, E, Smecher, GM, Sobrin, JA, Stark, AA, Stephen, J, Story, KT, Suzuki, A, Thompson, KL, Thorne, B, Tucker, CE, Umilta, C, Vale, LR, Vanderlinde, K, Vieira, JD, Wang, G, Whitehorn, N, Wu, WLK, Yefremenko, VG, Yoon, KW, Young, MR, Montgomery, J, Ade, PAR, Ahmed, Z, Anderes, E, Anderson, AJ, Archipley, MA, Avva, JS, Aylor, K, Balkenhol, L, Barry, PS, Thakur, RB, Benabed, K, Bender, AN, Benson, BA, Bianchini, F, Bleem, LE, Bouchet, FR, Bryant, L, Byrum, K, Carlstrom, JE, Carter, FW, Cecil, TW, Chang, CL, Chaubal, P, Chen, G, Cho, H-M, Chou, T-L, Cliche, J-F, Crawford, TM, Cukierman, AJ, Daley, CM, de Haan, T, Denison, E, Dibert, K, Ding, J, Dobbs, MA, Dutcher, D, Elleflot, T, Everett, WB, Feng, C, Ferguson, KR, Foster, A, Fu, J, Galli, S, Gambrel, AE, Gardner, RW, Goeckner-Wald, N, Groh, JC, Gualtieri, R, Guns, ST, Gupta, N, Guyser, RJ, Halverson, NW, Harke-Hosemann, AH, Harrington, NL, Henning, JW, Hilton, GC, Hivon, EF, Holzapfel, WL, Hood, JC, Howe, D, Huang, N, Irwin, KD, Jeong, OB, Jonas, M, Jones, A, Khaire, TS, Knox, L, Kofman, AM, Korman, M, Kubik, DL, Kuhlmann, SE, Kuo, C-L, Lee, AT, Leitch, EM, Lowitz, AE, Lu, C, Meyer, SS, Michalik, D, Millea, M, Nadolski, A, Natoli, TJ, Nguyen, H, Noble, G, Novosad, V, Omori, Y, Padin, S, Pan, Z, Paschos, P, Pearson, JE, Posada, CM, Prabhu, K, Quan, W, Rahlin, AS, Reichardt, CL, Riebel, D, Riedel, B, Rouble, M, Ruhl, JE, Sayre, JT, Schiappucci, E, Shirokoff, E, Smecher, GM, Sobrin, JA, Stark, AA, Stephen, J, Story, KT, Suzuki, A, Thompson, KL, Thorne, B, Tucker, CE, Umilta, C, Vale, LR, Vanderlinde, K, Vieira, JD, Wang, G, Whitehorn, N, Wu, WLK, Yefremenko, VG, Yoon, KW, and Young, MR

Abstract

The third-generation South Pole Telescope camera (SPT-3G) improves upon its predecessor (SPTpol) by an order of magnitude increase in detectors on the focal plane. The technology used to read out and control these detectors, digital frequency-domain multiplexing (DfMUX), is conceptually the same as used for SPTpol, but extended to accommodate more detectors. A nearly 5× expansion in the readout operating bandwidth has enabled the use of this large focal plane, and SPT-3G performance meets the forecasting targets relevant to its science objectives. However, the electrical dynamics of the higher-bandwidth readout differ from predictions based on models of the SPTpol system due to the higher frequencies used and parasitic impedances associated with new cryogenic electronic architecture. To address this, we present an updated derivation for electrical crosstalk in higher-bandwidth DfMUX systems and identify two previously uncharacterized contributions to readout noise, which become dominant at high bias frequency. The updated crosstalk and noise models successfully describe the measured crosstalk and readout noise performance of SPT-3G. These results also suggest specific changes to warm electronics component values, wire-harness properties, and SQUID parameters, to improve the readout system for future experiments using DfMUX, such as the LiteBIRD space telescope.

Published
2022

37. The Design and Integrated Performance of SPT-3G

Author

Sobrin, JA, Anderson, AJ, Bender, AN, Benson, BA, Dutcher, D, Foster, A, Goeckner-Wald, N, Montgomery, J, Nadolski, A, Rahlin, A, Ade, PAR, Ahmed, Z, Anderes, E, Archipley, M, Austermann, JE, Avva, JS, Aylor, K, Balkenhol, L, Barry, PS, Thakur, RB, Benabed, K, Bianchini, F, Bleem, LE, Bouchet, FR, Bryant, L, Byrum, K, Carlstrom, JE, Carter, FW, Cecil, TW, Chang, CL, Chaubal, P, Chen, G, Cho, H-M, Chou, T-L, Cliche, J-F, Crawford, TM, Cukierman, A, Daley, C, de Haan, T, Denison, E, Dibert, K, Ding, J, Dobbs, MA, Everett, W, Feng, C, Ferguson, KR, Fu, J, Galli, S, Gambrel, AE, Gardner, RW, Gualtieri, R, Guns, S, Gupta, N, Guyser, R, Halverson, NW, Harke-Hosemann, AH, Harrington, NL, Henning, JW, Hilton, GC, Hivon, E, Holder, GP, Holzapfel, WL, Hood, JC, Howe, D, Huang, N, Irwin, KD, Jeong, OB, Jonas, M, Jones, A, Khaire, TS, Knox, L, Kofman, AM, Korman, M, Kubik, DL, Kuhlmann, S, Kuo, C-L, Lee, AT, Leitch, EM, Lowitz, AE, Lu, C, Meyer, SS, Michalik, D, Millea, M, Natoli, T, Nguyen, H, Noble, G, Novosad, V, Omori, Y, Padin, S, Pan, Z, Paschos, P, Pearson, J, Posada, CM, Prabhu, K, Quan, W, Reichardt, CL, Riebel, D, Riedel, B, Rouble, M, Ruhl, JE, Saliwanchik, B, Sayre, JT, Schiappucci, E, Shirokoff, E, Smecher, G, Stark, AA, Stephen, J, Story, KT, Suzuki, A, Tandoi, C, Thompson, KL, Thorne, B, Tucker, C, Umilta, C, Vale, LR, Vanderlinde, K, Vieira, JD, Wang, G, Whitehorn, N, Wu, WLK, Yefremenko, V, Yoon, KW, Young, MR, Sobrin, JA, Anderson, AJ, Bender, AN, Benson, BA, Dutcher, D, Foster, A, Goeckner-Wald, N, Montgomery, J, Nadolski, A, Rahlin, A, Ade, PAR, Ahmed, Z, Anderes, E, Archipley, M, Austermann, JE, Avva, JS, Aylor, K, Balkenhol, L, Barry, PS, Thakur, RB, Benabed, K, Bianchini, F, Bleem, LE, Bouchet, FR, Bryant, L, Byrum, K, Carlstrom, JE, Carter, FW, Cecil, TW, Chang, CL, Chaubal, P, Chen, G, Cho, H-M, Chou, T-L, Cliche, J-F, Crawford, TM, Cukierman, A, Daley, C, de Haan, T, Denison, E, Dibert, K, Ding, J, Dobbs, MA, Everett, W, Feng, C, Ferguson, KR, Fu, J, Galli, S, Gambrel, AE, Gardner, RW, Gualtieri, R, Guns, S, Gupta, N, Guyser, R, Halverson, NW, Harke-Hosemann, AH, Harrington, NL, Henning, JW, Hilton, GC, Hivon, E, Holder, GP, Holzapfel, WL, Hood, JC, Howe, D, Huang, N, Irwin, KD, Jeong, OB, Jonas, M, Jones, A, Khaire, TS, Knox, L, Kofman, AM, Korman, M, Kubik, DL, Kuhlmann, S, Kuo, C-L, Lee, AT, Leitch, EM, Lowitz, AE, Lu, C, Meyer, SS, Michalik, D, Millea, M, Natoli, T, Nguyen, H, Noble, G, Novosad, V, Omori, Y, Padin, S, Pan, Z, Paschos, P, Pearson, J, Posada, CM, Prabhu, K, Quan, W, Reichardt, CL, Riebel, D, Riedel, B, Rouble, M, Ruhl, JE, Saliwanchik, B, Sayre, JT, Schiappucci, E, Shirokoff, E, Smecher, G, Stark, AA, Stephen, J, Story, KT, Suzuki, A, Tandoi, C, Thompson, KL, Thorne, B, Tucker, C, Umilta, C, Vale, LR, Vanderlinde, K, Vieira, JD, Wang, G, Whitehorn, N, Wu, WLK, Yefremenko, V, Yoon, KW, and Young, MR

Abstract

SPT-3G is the third survey receiver operating on the South Pole Telescope dedicated to high-resolution observations of the cosmic microwave background (CMB). Sensitive measurements of the temperature and polarization anisotropies of the CMB provide a powerful data set for constraining cosmology. Additionally, CMB surveys with arcminute-scale resolution are capable of detecting galaxy clusters, millimeter-wave bright galaxies, and a variety of transient phenomena. The SPT-3G instrument provides a significant improvement in mapping speed over its predecessors, SPT-SZ and SPTpol. The broadband optics design of the instrument achieves a 430 mm diameter image plane across observing bands of 95, 150, and 220 GHz, with 1.2′ FWHM beam response at 150 GHz. In the receiver, this image plane is populated with 2690 dual-polarization, trichroic pixels (∼16,000 detectors) read out using a 68× digital frequency-domain multiplexing readout system. In 2018, SPT-3G began a multiyear survey of 1500 deg2 of the southern sky. We summarize the unique optical, cryogenic, detector, and readout technologies employed in SPT-3G, and we report on the integrated performance of the instrument.

Published
2022

39. The Design and Integrated Performance of SPT-3G

Author

Sobrin, J. A., primary, Anderson, A. J., additional, Bender, A. N., additional, Benson, B. A., additional, Dutcher, D., additional, Foster, A., additional, Goeckner-Wald, N., additional, Montgomery, J., additional, Nadolski, A., additional, Rahlin, A., additional, Ade, P. A. R., additional, Ahmed, Z., additional, Anderes, E., additional, Archipley, M., additional, Austermann, J. E., additional, Avva, J. S., additional, Aylor, K., additional, Balkenhol, L., additional, Barry, P. S., additional, Thakur, R. Basu, additional, Benabed, K., additional, Bianchini, F., additional, Bleem, L. E., additional, Bouchet, F. R., additional, Bryant, L., additional, Byrum, K., additional, Carlstrom, J. E., additional, Carter, F. W., additional, Cecil, T. W., additional, Chang, C. L., additional, Chaubal, P., additional, Chen, G., additional, Cho, H.-M., additional, Chou, T.-L., additional, Cliche, J.-F., additional, Crawford, T. M., additional, Cukierman, A., additional, Daley, C., additional, Haan, T. de, additional, Denison, E. V., additional, Dibert, K., additional, Ding, J., additional, Dobbs, M. A., additional, Everett, W., additional, Feng, C., additional, Ferguson, K. R., additional, Fu, J., additional, Galli, S., additional, Gambrel, A. E., additional, Gardner, R. W., additional, Gualtieri, R., additional, Guns, S., additional, Gupta, N., additional, Guyser, R., additional, Halverson, N. W., additional, Harke-Hosemann, A. H., additional, Harrington, N. L., additional, Henning, J. W., additional, Hilton, G. C., additional, Hivon, E., additional, Holder, G. P., additional, Holzapfel, W. L., additional, Hood, J. C., additional, Howe, D., additional, Huang, N., additional, Irwin, K. D., additional, Jeong, O. B., additional, Jonas, M., additional, Jones, A., additional, Khaire, T. S., additional, Knox, L., additional, Kofman, A. M., additional, Korman, M., additional, Kubik, D. L., additional, Kuhlmann, S., additional, Kuo, C.-L., additional, Lee, A. T., additional, Leitch, E. M., additional, Lowitz, A. E., additional, Lu, C., additional, Meyer, S. S., additional, Michalik, D., additional, Millea, M., additional, Natoli, T., additional, Nguyen, H., additional, Noble, G. I., additional, Novosad, V., additional, Omori, Y., additional, Padin, S., additional, Pan, Z., additional, Paschos, P., additional, Pearson, J., additional, Posada, C. M., additional, Prabhu, K., additional, Quan, W., additional, Reichardt, C. L., additional, Riebel, D., additional, Riedel, B., additional, Rouble, M., additional, Ruhl, J. E., additional, Saliwanchik, B., additional, Sayre, J. T., additional, Schiappucci, E., additional, Shirokoff, E., additional, Smecher, G., additional, Stark, A. A., additional, Stephen, J., additional, Story, K. T., additional, Suzuki, A., additional, Tandoi, C., additional, Thompson, K. L., additional, Thorne, B., additional, Tucker, C., additional, Umilta, C., additional, Vale, L. R., additional, Vanderlinde, K., additional, Vieira, J. D., additional, Wang, G., additional, Whitehorn, N., additional, Wu, W. L. K., additional, Yefremenko, V., additional, Yoon, K. W., additional, and Young, M. R., additional

Published
2022
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40. A statistical focus on doping using a metabolomics approach

Author

Keen, B, Cawley, A, Reedy, B, Noble, G, and Fu, S

Subjects
Health, Toxicology and Mutagenesis, Toxicology
Abstract

Aim Identify potential biomarkers that are indicative of doping in equine plasma through statistical analysis of metabolomics data. Introduction The purpose of metabolomics is to detect endogenous changes in molecular entities, such as metabolites and adducts, that are indicative of challenges to the system (Fiehn et al., Metabolomics, 2015, 11, 1036–1040). These challenges to the system may include things such as doping, disease and environmental changes. Doping is an ever-growing field due to the changing nature of new and popular agents. For the racing industry, any performance altering agents are prohibited to maintain the welfare of athletes involved and the integrity of the sport and breeding industry (Cawley et al., Drug Testing and Analysis, 2017, 9, 1441–1447). Therefore, an alternative approach to conventional detection methods is essential for the decreasing the bottleneck that is the introduction of new compounds into routine screening efforts. Method Using only 100μL of equine plasma, a rapid protein precipitation method was developed for the analysis of endogenous compounds. The IMTAKT Intrada Amino Acid column (100mm×2mm, 3μm) was able to separate dopamine-related compounds. The method used positive and negative ionisation mode with an 11-minute gradient method on the Agilent 1290 Infinity II LC system coupled to an Agilent 6545 QTOF mass spectrometer. A substantial reference population study was completed to assess basal concentrations of endogenous compounds of interest. A 12-horse administration study of Stalevo® (800mg levodopa, 200mg carbidopa, 1600mg entacapone) was analysed. Agilent Technologies’ Profinder was used to complete a batch recursive feature extraction of the data. The statistical analysis included longitudinal profiling and identification of significant entities through volcano plot analysis, principal component analysis and heatmap visualisation. Biomarker quality was determined using a ‘best biomarker quality (BBQ)’ assessment. Re

Published
2022
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41. Synthesis and study of evolutionary optimised sensor linearisation with translinear & FPGA circuits.

Author

Sundararajan, S., Kottarthil Naduvil, Madhusoodanan, Abudhahir, A, Karuna, K T Gandhi, and Noble, G

Subjects
FIELD programmable gate arrays, APPLICATION-specific integrated circuits, GALLIUM nitride, DATA conversion, NONLINEAR functions, ELECTRON mobility
Abstract

Linear response characteristics of sensors are affected by ageing and changes in material properties. However, existing methods for improving these characteristics are disadvantaged by recurrent full-scale errors and insufficient speed. Accordingly, this study aims to reduce temperature sensor non-linearity through implementation of evolutionary optimised non-linear functions via a translinear-based application-specific integrated circuit. Moreover, the translinear-based analogue computation method is compared to a proposed field programmable gate array (FPGA)-based digital computation methodology to develop an alternative method for linearisation at sensor nodes (edge computing). The optimal values of the linearisation parameters for selected thermocouples are determined using the covariance matrix adaptation evolutionary strategy. Specifically, these optimal values are input in order to realise the non-linear functions. Experimental results reveal that FPGA offers a lower full-scale error than that of the translinear-based computation, although the translinear method can accomplish the required linearisation with fewer components (e.g. Data Converters), less delay and less power. Further, analogue computation through the proposed single chip-based method can utilise the latest processes, e.g. gallium nitride or pseudomorphic high electron mobility, for an enhanced error reduction. The comparative result shows that the translinear method with recommended processes can correct the non-linearity of sensors in all aspects. [ABSTRACT FROM AUTHOR]

Published
2022
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42. The human glucocorticoid receptor variant rs6190 promotes blood cholesterol and atherosclerosis.

Author

Durumutla HB, Haller A, Noble G, Prabakaran AD, McFarland K, Latimer H, Akinborewa O, Namjou-Khales B, Hui DY, and Quattrocelli M

Abstract

Elevated cholesterol poses a significant cardiovascular risk, particularly in older women. The glucocorticoid receptor (GR), a crucial nuclear transcription factor that regulates the metabolism of virtually all major nutrients, harbors a still undefined role in cholesterol regulation. Here, we report that a coding single nucleotide polymorphism (SNP) in the gene encoding the GR, rs6190 , associated with increased cholesterol levels in women according to UK Biobank and All Of Us datasets. In SNP-genocopying transgenic mice, we found that the rs6190 SNP enhanced hepatic GR activity to transactivate Pcsk9 and Bhlhe40 , negative regulators of low-density lipoprotein (LDL) and high-density lipoprotein (HDL) receptors in liver respectively. Accordingly, in mice the rs6190 SNP was sufficient to elevate circulating cholesterol levels across all lipoprotein fractions and the risk and severity of atherosclerotic lesions on the pro-atherogenic hAPOE*2/*2 background. The SNP effect on atherosclerosis was blocked by in vivo knockdown of Pcsk9 and Bhlhe40 in liver. Remarkably, we found that this mechanism was conserved in human hepatocyte-like cells using CRISPR-engineered, SNP-genocopying human induced pluripotent stem cells (hiPSCs). Taken together, our study leverages a non-rare human variant to uncover a novel GR-dependent mechanism contributing to atherogenic risk, particularly in women., Competing Interests: Conflicts of Interest – MQ is listed as co-inventor on a patent application related to intermittent glucocorticoid use filed by Northwestern University (PCT/US2019/068,618), unrelated to any aspects of this study. All other authors declare they have no competing interests.

Published
2024
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43. Lipid and Corticosteroid Biomarkers Under the Influence of Bisphosphonates.

Author

Tou K, Cawley A, Noble G, Loy J, Bishop D, Keledjian J, Sornalingam K, Richards S, and Fu S

Abstract

Detecting the use of bisphosphonates (BPs) in equine athletes is of interest to regulators and laboratories due to the threat to welfare issues for the potential to provide analgesic effects and manipulating bone structure. The detection of BPs in biological matrices is challenging due to erratic biological elimination and inconsistent analytical recoveries. Therefore, complementary approaches are needed to provide evidence of their misuse in racehorses. BPs have two sub-classes: nitrogenous and non-nitrogenous. This study investigated plasma elimination following administration of one example from each sub-class, together with changes in endogenous eicosanoid and corticosteroids. Zoledronic acid (ZA) and tiludronic acid (TA) were administered by IV infusion to 8 thoroughbred horses with an 11-month washout period between each administration. Sample preparation for quantification of BPs by liquid chromatography-tandem mass spectrometry (LC-MS/MS) utilised a two-step solid phase extraction (SPE) consisting of polymeric reversed-phase followed by weak anion exchange prior to derivatisation using trimethyl orthoacetate. Endogenous biomarkers were analysed after protein precipitation and SPE with polymeric reversed-phase prior to liquid chromatography-high resolution mass spectrometry (LC-HRMS) using data independent acquisition. The LC-MS/MS analysis showed ZA was undetectable after 8 h post-administration while TA was detected up to the final collection point of 28 days post-administration. The LC-HRMS analysis utilised targeted (i.e., prior inclusion list of compounds) approaches to monitor level changes of eicosanoid and corticosteroid biomarkers. Putative biomarkers were identified and now subject to validation for translation into routine sample analysis for improved retrospectivity to detecting BP misuse in equine plasma., (© 2024 The Author(s). Drug Testing and Analysis published by John Wiley & Sons Ltd.)

Published
2024
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44. The Intersectionality of Food Insecurity, Job Insecurity, Healthcare Insecurity, and Mental Health Challenges in NYC Households During Covid-19.

Author

Gadhoke P, Brenton BP, Sadeghzadeh S, Huang SY, Lane L, Mathieu D, Rafa T, Albano X, and Noble G

Subjects
Humans, Mental Health, Job Security, Intersectional Framework, Food Supply, Food Insecurity, Delivery of Health Care, COVID-19 epidemiology
Abstract

Our intersectional research explored food insecurity and job insecurity as predictors of healthcare insecurity and mental health challenges among households living in economic instability since the COVID19 pandemic began. The New York City COVID19 Research Team adapted a validated, web based, anonymous survey questionnaire using a Social Determinants of Health Framework. The study oversampled underserved populations with a total of 2,099 participants. We report strong associations between food insecurity and job insecurity among healthcare insecure households, and significant mental health challenges among food insecure and healthcare insecure households. This underscores the need for integrated social policies to protect underserved urban populations.

Published
2024
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45. Microwave therapy for the treatment of plantar warts.

Author

Hagon W, Hagon J, Noble G, Brenton-Rule A, Stewart S, and Bristow I

Subjects
Humans, Retrospective Studies, Microwaves therapeutic use, Pain Management, Treatment Outcome, Warts drug therapy, Foot Diseases therapy
Abstract

Background: Plantar warts, or verrucae plantaris, are common lesions causing considerable pain during weightbearing activity. Although current treatment modalities have low success rates, microwave therapy has been introduced as a promising intervention. This study aimed to determine the effectiveness of microwave therapy for the treatment of plantar warts and to determine the clinical factors associated with plantar wart resolution., Methods: A retrospective analysis of 150 plantar warts from 45 patients treated with microwave therapy was undertaken. Binomial regression was conducted to explore clinical characteristics (age, gender, immunosuppression, impaired healing, multiple vs single wart, location of lesion, lesion diameter) associated with lesion resolution., Results: Of the total 150 plantar warts treated with microwave therapy, 125 (83.3%) warts resolved and 25 (17%) warts did not resolve. The mean (SD) total treatment sessions for resolved lesions was 2.8 (1.0). Decreasing age (P = 0.046) was the only clinical characteristic associated with resolution., Conclusions: This retrospective study has shown that plantar warts may be resolved with two to three sessions of microwave therapy, which may be more successful in younger populations., (© 2023. The Author(s).)

Published
2023
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46. Imputed genomes and haplotype-based analyses of the Picts of early medieval Scotland reveal fine-scale relatedness between Iron Age, early medieval and the modern people of the UK.

Author

Morez A, Britton K, Noble G, Günther T, Götherström A, Rodríguez-Varela R, Kashuba N, Martiniano R, Talamo S, Evans NJ, Irish JD, Donald C, and Girdland-Flink L

Subjects
Humans, Female, Haplotypes genetics, Scotland, Gene Frequency, DNA, Mitochondrial genetics
Abstract

There are longstanding questions about the origins and ancestry of the Picts of early medieval Scotland (ca. 300-900 CE), prompted in part by exotic medieval origin myths, their enigmatic symbols and inscriptions, and the meagre textual evidence. The Picts, first mentioned in the late 3rd century CE resisted the Romans and went on to form a powerful kingdom that ruled over a large territory in northern Britain. In the 9th and 10th centuries Gaelic language, culture and identity became dominant, transforming the Pictish realm into Alba, the precursor to the medieval kingdom of Scotland. To date, no comprehensive analysis of Pictish genomes has been published, and questions about their biological relationships to other cultural groups living in Britain remain unanswered. Here we present two high-quality Pictish genomes (2.4 and 16.5X coverage) from central and northern Scotland dated from the 5th-7th century which we impute and co-analyse with >8,300 previously published ancient and modern genomes. Using allele frequency and haplotype-based approaches, we can firmly place the genomes within the Iron Age gene pool in Britain and demonstrate regional biological affinity. We also demonstrate the presence of population structure within Pictish groups, with Orcadian Picts being genetically distinct from their mainland contemporaries. When investigating Identity-By-Descent (IBD) with present-day genomes, we observe broad affinities between the mainland Pictish genomes and the present-day people living in western Scotland, Wales, Northern Ireland and Northumbria, but less with the rest of England, the Orkney islands and eastern Scotland-where the political centres of Pictland were located. The pre-Viking Age Orcadian Picts evidence a high degree of IBD sharing across modern Scotland, Wales, Northern Ireland, and the Orkney islands, demonstrating substantial genetic continuity in Orkney for the last ~2,000 years. Analysis of mitochondrial DNA diversity at the Pictish cemetery of Lundin Links (n = 7) reveals absence of direct common female ancestors, with implications for broader social organisation. Overall, our study provides novel insights into the genetic affinities and population structure of the Picts and direct relationships between ancient and present-day groups of the UK., Competing Interests: The authors have declared that no competing interests exist., (Copyright: © 2023 Morez et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)

Published
2023
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47. 90 vs 50-Watt Radiofrequency Applications for Pulmonary Vein Isolation: Experimental and Clinical Findings.

Author

Bortone A, Albenque JP, Ramirez FD, Haïssaguerre M, Combes S, Constantin M, Laborie G, Brault-Noble G, Marijon É, Jaïs P, and Pambrun T

Subjects
Animals, Catheters, Heart Atria surgery, Humans, Recurrence, Swine, Treatment Outcome, Atrial Fibrillation diagnosis, Atrial Fibrillation surgery, Catheter Ablation adverse effects, Catheter Ablation methods, Pulmonary Veins surgery
Abstract

Background: Fifty-watt radiofrequency applications have proven to be safe and efficient for pulmonary vein isolation (PVI). However, as PV reconnection still occurs and ablation catheter instability significantly contributes to suboptimal lesion formation, a new ablation catheter capable of delivering 90 W for 4 seconds only has been developed with the aim of improving PVI outcomes. In this setting, we sought to determine whether 90 W applications create transmural lesions without collateral damage experimentally and whether they can safely improve PVI procedures clinically compared with 50 W settings., Methods: Experimentally, individual lesions were created in vivo in the right atrium of 6 swine with 90 W-4 seconds applications using the SmartTouch-SF catheter in a power-controlled mode (3 animals) or the QDOT-MICRO catheter in a temperature-controlled mode (3 animals). Clinically, PVI was performed in a homogenous population of 150 consecutive paroxysmal atrial fibrillation patients using CARTO and the QDOT-MICRO catheter in a temperature-controlled mode (75 patients 50 W-ablation index-guided and 75 patients 90 W-4 seconds)., Results: Mostly, (94.9%) experimental lesions were transmural in the thin-walled right atrium of swine. However, collateral damage was observed with both catheters in 17.9% of lesions. Clinically, 90 W procedures had a lower first-pass PVI rate (49% versus 81%, P <10 -4 ) and a higher acute PV reconnection rate (21% versus 5%, P =0.004) than 50 W procedures, whereas total procedural duration (62 versus 66 minutes, P =0.09), 1-year sinus rhythm maintenance (88% versus 90%, P =0.6) and safety (1 tamponade per group) were similar in both groups., Conclusions: Experimentally, using the QDOT-MICRO catheter, 90 W-4 seconds lesions are mostly transmural in the thin-walled right atrium of swine (median depth 1.87 mm) with a moderate lesion diameter of 6.62 mm but retain the potential for collateral damage. Clinically, 90 W-4 seconds applications are associated with a lower first-pass PVI rate and a higher acute PV reconnection rate than 50 W applications but similar safety outcomes and effectiveness at 1 year.

Published
2022
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48. A case of blepharophimosis: Freeman Sheldon syndrome.

Author

Bowman S, Noble G, Rahmani B, Mets M, Ralay Ranaivo H, and Castelluccio V

Subjects
Humans, Infant, Blepharophimosis diagnosis, Blepharophimosis genetics, Blepharophimosis surgery, Craniofacial Dysostosis diagnosis, Craniofacial Dysostosis genetics, Lacrimal Duct Obstruction, Nasolacrimal Duct
Abstract

Purpose: Important implications exist for ophthalmologists when considering possible early surgical intervention for potential amblyogenic anatomical abnormalities. The authors discuss the risks and benefits from an ophthalmological perspective of different interventions and review the genetic testing that confirmed the diagnosis., Observations: The authors describe the findings and management of an infant with Freeman Sheldon syndrome presenting with blepharophimosis of both eyelids resulting in inability to open both eyes during the first several days of life. Although the mode of inheritance for Freeman Sheldon syndrome (formerly known as Whistling Face Syndrome) is often autosomal dominant, our patient had no known family history of congenital abnormalities or consanguinity. However, genetic testing confirmed a heterozygous variant in MYH3 , consistent with autosomal dominant Freeman Sheldon Syndrome. When our patient required gastrostomy (G-tube&#95;placement, we performed an exam under anesthesia (EUA)). As is typical for Freeman Sheldon syndrome patients, intubation was difficult and complicated by pneumothorax. Eye-opening improved slightly after several weeks of life; however, the decision was made to proceed with eyelid surgery to prevent deprivation amblyopia. Surgery is scheduled for a future date. Additionally, the patient had congenital nasolacrimal duct obstruction of the left eye; however, a probing and irrigation failed because of obstruction from the abnormal facial anatomy., Conclusions and Importance: Patients with Freeman Sheldon syndrome are at increased risk for complications from anesthesia and surgery. Risks and benefits should be strongly considered and discussed with parent(s)/guardian(s) prior to any surgical intervention. Genetic testing of the MYH3 gene can confirm the diagnosis.

Published
2022
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