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Your search keyword '"Ngama, Mwanajuma"' showing total 7 results
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7 results on '"Ngama, Mwanajuma"'

1. Mosquitocidal efficacy and pharmacokinetics of single-dose ivermectin versus three-day dose regimen for malaria vector control compared with albendazole and no treatment: An open-label randomized controlled trial

Author

Kamau, Yvonne, Tuwei, Mercy, Wanjiku, Caroline, Ominde, Kelly, Ngama, Mwanajuma, Karisa, Jonathan, Babu, Lawrence, Muturi, Martha, Mwatasa, Mwaganyuma, Adetifa, Jane, Kern, Charlotte, Duthaler, Urs, Hammann, Felix, Rabinovich, Regina, Chaccour, Carlos, and Maia, Marta Ferreira

Published
2024
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2. A global core outcome measurement set for snakebite clinical trials

Author

Abouyannis, Michael, Aggarwal, Dinesh, Alcoba, Gabriel, Alphan, Hassan J, Cammack, Nick, Casewell, Nicholas R, Chippaux, Jean-Philippe, Coldiron, Matthew E, Esmail, Hanif, Gutiérrez, José M, Habib, Abdulrazaq G, Hamaluba, Mainga, Harrison, Robert A, Isbister, Geoffrey K, Lalloo, David G, Lavonas, Eric J, Martins, Diogo, Mumba, Noni, Mwalukore, Salim, Mwangudzah, Hope, Ngama, Mwanajuma, Ribeiro, Isabela, Walker, A Sarah, Watson, James A, Williams, David J, Yeri, Betty K, Bammigatti, Chanaveerappa, Carter, Rebecca W, Gerardo, Charles J, de Silva, H Janaka, Lamb, Thomas, Lewin, Matthew R, Monteiro, Wuelton, Stienstra, Ymkje, and Walker, Sarah A

Published
2023
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4. Identifying the research, advocacy, policy and implementation needs for the prevention and management of respiratory syncytial virus lower respiratory tract infection in low- and middle-income countries

Author

Carbonell-Estrany, Xavier, primary, Simões, Eric A. F, additional, Bont, Louis J, additional, Gentile, Angela, additional, Homaira, Nusrat, additional, Scotta, Marcelo Comerlato, additional, Stein, Renato T, additional, Torres, Juan P, additional, Sheikh, Jarju, additional, Broor, Shobha, additional, Khuri-Bulos, Najwa, additional, Nokes, D James, additional, Munywoki, Patrick K, additional, Bassat, Quique, additional, Sharma, Arun K, additional, Basnet, Sudha, additional, Garba, Maria, additional, De Jesus-Cornejo, Joanne, additional, Lupisan, Socorro P, additional, Nunes, Marta C, additional, Divarathna, Maduja, additional, Fullarton, John R, additional, Rodgers-Gray, Barry S, additional, Keary, Ian, additional, Reñosa, Mark Donald C, additional, Verwey, Charl, additional, Moore, David P, additional, Noordeen, Faseeha, additional, Kabra, Sushil, additional, do Vale, Marynéa Silva, additional, Paternina-De La Ossa, Rolando, additional, Mariño, Cristina, additional, Figueras-Aloy, Josep, additional, Krilov, Leonard, additional, Berezin, Eitan, additional, Zar, Heather J, additional, Paudel, Krishna, additional, Safadi, Marco Aurelio Palazzi, additional, Dbaibo, Ghassan, additional, Jroundi, Imane, additional, Jha, Runa, additional, Rafeek, Rukshan A. M, additional, Pinheiro, Rossiclei de Souza, additional, Bracht, Marianne, additional, Muthugala, Rohitha, additional, Lanari, Marcello, additional, Martinón-Torres, Federico, additional, Mitchell, Ian, additional, Irimu, Grace, additional, Pandey, Apsara, additional, Krishnan, Anand, additional, Mejias, Asuncion, additional, da Costa, Marcela Santos Corrêa, additional, Shrestha, Shrijana, additional, Pernica, Jeffrey M, additional, de Carvalho, Felipe Cotrim, additional, Jalango, Rose E, additional, Ibrahim, Hafsat, additional, Ewa, Atana, additional, Ensinck, Gabriela, additional, Ulloa-Gutierrez, Rolando, additional, Miralha, Alexandre Lopes, additional, Lucion, Maria Florencia, additional, Hassan, Md Zakiul, additional, Akhtar, Zubair, additional, Aleem, Mohammad Abdul, additional, Chowdhury, Fahmida, additional, Rojo, Pablo, additional, Sande, Charles, additional, Musau, Abednego, additional, Zaman, Khalequ, additional, Helena, Luiza, additional, Arlant, Falleiros, additional, Ghimire, Prakash, additional, Price, April, additional, Subedi, Kalpana Upadhyay, additional, Brenes-Chacon, Helena, additional, Goswami, Doli Rani, additional, Rahman, Mohammed Ziaur, additional, Hossain, Mohammad Enayet, additional, Chisti, Mohammod Jobayer, additional, Vain, Nestor E, additional, Lim, Audrey, additional, Chiu, Aaron, additional, Papenburg, Jesse, additional, Juarez, Maria del Valle, additional, Senaratne, Thamarasi, additional, Arunasalam, Shiyamalee, additional, Strand, Tor A, additional, Ayuk, Adaeze, additional, Ogunrinde, Olufemi, additional, Tavares, Lohanna Valeska de Sousa, additional, Garba, Comfort, additional, Garba, Bilkisu I, additional, Dawa, Jeanette, additional, Gordon, Michelle, additional, Osoro, Eric, additional, Agoti, Charles N, additional, Nyawanda, Bryan, additional, Ngama, Mwanajuma, additional, Tabu, Collins, additional, Mathew, Joseph L, additional, Cornacchia, Andrew, additional, Rai, Ganesh Kumar, additional, Jain, Amita, additional, Giongo, Mateus Sfoggia, additional, and Paes, Bosco A, additional

Published
2022
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5. TRUE-1: Trial of Repurposed Unithiol for snakebite Envenoming phase 1 (safety, tolerability, pharmacokinetics and pharmacodynamics in healthy Kenyan adults)

Author

Abouyannis, Michael, primary, FitzGerald, Richard, additional, Ngama, Mwanajuma, additional, Mwangudzah, Hope, additional, Nyambura, Yvonne K., additional, Ngome, Samson, additional, Riako, Debra, additional, Babu, Lawrence, additional, Lewa, Frida, additional, Else, Laura, additional, Dily Penchala, Sujan, additional, Orindi, Benedict, additional, Mumba, Noni, additional, Kalama, Betty, additional, Ndungu, Francis M., additional, Adetifa, Ifedayo, additional, Khoo, Saye, additional, Lalloo, David G., additional, Casewell, Nicholas R., additional, and Hamaluba, Mainga, additional

Published
2022
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6. Identification of missed respiratory viruses by metagenomic sequencing of clinical respiratory samples from Kenya

Author

Phan, My V. T., Agoti, Charles N., Munywoki, Patrick K., Otieno, Grieven Paul, Ngama, Mwanajuma, Kellam, Paul, Cotton, Matthew, and Nokes, D. James

Subjects
viruses
Abstract

Pneumonia remains a major cause of mortality and morbidity. Most molecular diagnoses of viruses rely on polymerase chain reaction (PCR) assays that however can fail due to primer mismatch. We investigated the performance of routine virus diagnostics in Kilifi, Kenya, using random-primed viral next generation sequencing (viral NGS) on respiratory samples which tested negative for the common viral respiratory pathogens by a local standard diagnostic panel. Among 95 hospitalised pneumonia patients and 95 household-cohort individuals, analysis of viral NGS identified at least one respiratory-associated virus in 35 (37%) and 23 (24%) samples, respectively. The majority (66%; 42/64) belonged to the Picornaviridae family. The NGS data analysis identified a number of viruses that were missed by the diagnostic panel (rhinovirus, human metapneumovirus, respiratory syncytial virus and parainfluenza virus), and these failures could be attributed to PCR primer/probe binding site mismatches. Unexpected viruses identified included parvovirus B19, enterovirus D68, coxsackievirus A16 and A24 and rubella virus. The regular application of such viral NGS could help evaluate assay performance, identify molecular causes of missed diagnoses and reveal gaps in the respiratory virus set used for local screening assays. The results can provide actionable information to improve the local pneumonia diagnostics and reveal locally important viral pathogens.\ud \ud

Published
2022

7. [A global core outcome measurement set for snakebite clinical trials].

Author

Abouyannis M, Esmail H, Hamaluba M, Ngama M, Mwangudzah H, Mumba N, Yeri BK, Mwalukore S, Alphan HJ, Aggarwal D, Alcoba G, Cammack N, Chippaux JP, Coldiron ME, Gutiérrez JM, Habib AG, Harrison RA, Isbister GK, Lavonas EJ, Martins D, Ribeiro I, Watson JA, Williams DJ, Casewell NR, Walker SA, and Lalloo DG

Subjects
Humans, Consensus, Disability Evaluation, Outcome Assessment, Health Care, Surveys and Questionnaires, Snake Bites diagnosis, Clinical Trials as Topic
Abstract

Background: Snakebite clinical trials have often used heterogeneous outcome measures and there is an urgent need for standardisation., Method: A globally representative group of key stakeholders came together to reach consensus on a globally relevant set of core outcome measurements. Outcome domains and outcome measurement instruments were identified through searching the literature and a systematic review of snakebite clinical trials. Outcome domains were shortlisted by use of a questionnaire and consensus was reached among stakeholders and the patient group through facilitated discussions and voting., Results: Five universal core outcome measures should be included in all future snakebite clinical trials: mortality, WHO disability assessment scale, patient-specific functional scale, acute allergic reaction by Brown criteria, and serum sickness by formal criteria. Additional syndrome-specific core outcome measures should be used depending on the biting species., Conclusion: This core outcome measurement set provides global standardisation, supports the priorities of patients and clinicians, enables meta-analysis, and is appropriate for use in low-income and middle-income settings., (Copyright © 2023 SFMTSI.)

Published
2023
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