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Your search keyword '"Mintaroem, Karyono"' showing total 12 results
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12 results on '"Mintaroem, Karyono"'

5. DEDIFFERENTIATED LEIOMYOSARCOMA

Author

Putri, Anggie Sasmita Kharisma, primary, Retnani, Diah Prabawati, additional, Angelina, Aina, additional, Al Rasyid, Harun, additional, Mintaroem, Karyono, additional, Norahmawati, Eviana, additional, and Fadli, M Luqman, additional

Published
2023
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7. The effect of soy milk on estrogen receptor alpha expression in medial preoptic area (MPOA) and in spermatogonia, testosterone levels, and androgen receptors expression in male wistar rats (Rattus norvegicus)

Author

Nurdiana, Nurdiana, primary, Chania, Made Pradnyawati, additional, Nurvitasari, Rifzi Devi, additional, Nisa, Azmiatun, additional, Diana, Styan Wahyu, additional, Rochmah, Evalina Izzatur, additional, Mayangsari, Elly, additional, Rahardjo, Bambang, additional, Indrawan, I. Wayan Agung, additional, Khotimah, Husnul, additional, Mintaroem, Karyono, additional, Norahmawati, Eviana, additional, and Raras, Tri Yudani Mardining, additional

Published
2023
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9. Physalis angulata Leaf Ethanol Extract Reduces Oxidative Stress and Improves Endothelial Progenitor Cells in L-NAME-Induced Hypertensive Rats

Author

Nugrahenny, Dian, primary, Permatasari, Nur, additional, Soeharto, Setyawati, additional, Rahayu, Indriati Dwi, additional, Widodo, Edwin, additional, Mintaroem, Karyono, additional, Sujuti, Hidayat, additional, Ratnawati, Retty, additional, Mayangsari, Elly, additional, Irnandi, Dicky Faizal, additional, Ardani, Lavina Sofia, additional, Wardoyo, Tika Ardhini, additional, Claresta, Nathania Bella, additional, Yoga, Nura Fattah Cantika, additional, Anindita, Adinda Chika, additional, Siarnu, Niarti Ulan Sari, additional, and Alia, Fardizia Putri, additional

Published
2022
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10. Physalis angulata leaf extract ameliorates L-NG-nitroarginine methyl ester (L-NAME)-induced preeclampsia symptoms in rats through improved endothelial progenitor cells and endothelial cells due to reduced antiangiogenic factor and oxidative stress

Author

Nugrahenny, Dian, primary, Rudijanto, Achmad, additional, Permatasari, Nur, additional, Wiyasa, I Wayan Arsana, additional, Widodo, Mohammad Aris, additional, Mintaroem, Karyono, additional, Widjajanto, Edi, additional, and Mustofa, Mustofa, additional

Published
2022
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11. Physalis angulata Leaf Ethanol Extract Reduces Oxidative Stress and Improves Endothelial Progenitor Cells in L-NAME-Induced Hypertensive Rats.

Author

Nugrahenny, Dian, Permatasari, Nur, Soeharto, Setyawati, Rahayu, Indriati Dwi, Widodo, Edwin, Mintaroem, Karyono, Sujuti, Hidayat, Ratnawati, Retty, Mayangsari, Elly, Irnandi, Dicky Faizal, Ardani, Lavina Sofia, Wardoyo, Tika Ardhini, Claresta, Nathania Bella, Yoga, Nura Fattah Cantika, Anindita, Adinda Chika, Siarnu, Niarti Ulan Sari, and Alia, Fardizia Putri

Subjects
ETHANOL, ENDOTHELIAL cells, DIASTOLIC blood pressure, HYPERTENSION, OXIDATIVE stress, SYSTOLIC blood pressure, PROGENITOR cells
Abstract

This study aimed to evaluate the effects of ciplukan (Physalis angulata L.) leaf ethanol extract on L-NG-nitroarginine methyl ester (L-NAME)-induced hypertensive rats. We randomly divided twenty-five Wistar rats into five groups. The sham group was given a PBS injection. The hypertensive group was injected with L-NAME on days 1 to 28. Three groups of hypertensive rats were given the extract on days 4 to 28. Blood pressure was measured using the tail-cuff method on days 0, 4, 10, and 27. The endothelial progenitor cells (EPCs) in the blood were measured by flow cytometry as a percentage of circulating angiogenic cells (CACs, CD34+/CD309+/CD45+) and endothelial colony-forming cells (ECFCs, CD34+/CD309+/CD45-). Serum NO and MDA levels, as well as serum SOD activity, were measured colorimetrically. Serum TNF-a levels were measured by the ELISA method. The ciplukan leaf extract reduced systolic and diastolic blood pressure, reduced the percentage of EPCs in the blood, increased serum NO levels, reduced MDA levels, increased serum SOD activity, and reduced serum TNF-a levels in L-NAME-induced hypertensive rats. It is concluded that ciplukan ethanol leaf extract exerts protective effects on L-NAME-induced hypertensive rats. These study results can strengthen the scientific basis of using ciplukan leaf ethanol extract to treat hypertension. [ABSTRACT FROM AUTHOR]

Published
2023
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