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Your search keyword '"McColl, Elaine"' showing total 34 results
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34 results on '"McColl, Elaine"'

2. The Infant KIdney Dialysis and Utrafiltration (I-KID) Study: A Stepped-Wedge Cluster-Randomized Study in Infants, Comparing Peritoneal Dialysis, Continuous Venovenous Hemofiltration, and Newcastle Infant Dialysis Ultrafiltration System, a Novel Infant Hemodialysis Device

Author

Lambert, Heather, Hiu, Shaun, Coulthard, Malcolm G., Matthews, John N. S., Holstein, Eva-Maria, Crosier, Jean, Agbeko, Rachel, Brick, Thomas, Duncan, Heather, Grant, David, Mok, Quen, Nyman, Andrew Gustaf, Pappachan, John, Boucher, Chris, Bulmer, Joe, Chisholm, Denise, Cromie, Kirsten, Emmet, Victoria, Feltbower, Richard G., Ghose, Arunoday, Grayling, Michael, Harrison, Rebecca, Kennedy, Ciara A., McColl, Elaine, Morris, Kevin, Norman, Lee, Office, Julie, Parslow, Roger, Pattinson, Christine, Sharma, Shriya, Smith, Jonathan, Steel, Alison, Steel, Rachel, Straker, Jayne, Vrana, Lamprini, Walker, Jenn, Wellman, Paul, Whitaker, Mike, Wightman, Jim, Wilson, Nina, Wirz, Lucy, and Wood, Ruth

Published
2023
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7. Health related quality of life in young, steroid-naïve boys with Duchenne muscular dystrophy

Author

Straub, Volker, Childs, Anne-Marie, Ciafaloni, Emma, Shieh, Perry B., Spinty, Stefan, Butterfield, Russell J., Horrocks, Iain, Roper, Helen, Maggi, Lorenzo, Baranello, Giovanni, Flanigan, Kevin M., Kuntz, Nancy L., Manzur, Adnan Y., Darras, Basil T., Kang, Peter, Mah, Jean K., Mongini, Tiziana, Ricci, Federica, Morrison, Leslie, Krzesniak-Swinarska, Monika, von der Hagen, Maja, Finkel, Richard S., Kumar, Ashutosh, Wicklund, Matthew, McDonald, Craig M., Henricson, Erik K., Schara-Schmidt, Ulrike, Wilichowski, Ekkehard, Barohn, Richard J., Statland, Jeffrey, Kirschner, Janbernd, Vita, Giuseppe, Vita, Gian Luca, Howard, James F., Jr., Hughes, Imelda, McMillan, Hugh J., Pegoraro, Elena, Bello, Luca, Burnette, W. Bryan, Thangarajh, Mathula, Chang, Taeun, Campbell, Craig, McColl, Elaine, McDermott, Michael P., Martens, William B., Guglieri, Michela, and Griggs, Robert C.

Published
2021
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11. Delivering smoking cessation interventions in NHS primary dental care - lessons from the ENHANCE-D trial

Author

Weke, Anthony, Holmes, Richard D., McColl, Elaine, Finch, Roland, Butcher, Chrissie, and Holliday, Richard

Abstract

IntroductionSmoking is a major contributor to health inequalities in the UK. The ENHANCE-D trial is evaluating three smoking cessation interventions (nicotine replacement therapy [NRT], electronic cigarettes [ECs] or ‘very brief advice') delivered in NHS primary dental care. This qualitative study aimed to provide insight into the factors that could influence the adoption of the interventions in these settings.

Published
2024
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14. P284 Evaluation of a self-management smartphone app for those living with Sjögren’s syndrome: a fully remote randomised pilot and feasibility trial

Author

McCallum, Claire, Birjandi, Parvin Asadzadeh, Pakpahan, Eduwin, Campbell, Miglena, Vines, John, McCay, Kevin, McColl, Elaine, Hackett, Katie, McCallum, Claire, Birjandi, Parvin Asadzadeh, Pakpahan, Eduwin, Campbell, Miglena, Vines, John, McCay, Kevin, McColl, Elaine, and Hackett, Katie

Abstract

Background/Aims People with Sjögren's Syndrome (SS) experience a range of symptoms, including dryness, pain, fatigue, and poor sleep. Pharmacological management is limited, and SS patients may not have timely access to non-pharmacological support with these symptoms. Accessible evidence-based support via an app may benefit some. An evidence-based app (Sjogo) was co-developed with SS patients through a series of focus groups and workshops (n = 7). Alongside the workshops, behaviour change techniques and evidence-based intervention components were identified from the literature and known evidence-based interventions and were discussed with participants in focus groups. An app was developed containing active ingredients (e.g. features supporting behaviour change, validation of experiences, reflective activity diary, goal setting, cognitive behaviour therapy for sleep) to facilitate participation in daily activities and support symptom management. An additional control app was developed which contained “information only” content. We conducted a fully remote pilot feasibility RCT of the app. The aim of the study was to test trial procedures including recruitment rates, outcome completion, and engagement with the app. Methods The Sjogo app was released internationally for 8 weeks on Android and iOS app stores in January 2021. Potential participants were alerted to the trial through social media and patient groups. Those who downloaded the app were guided through in-app study procedures (screening, informed consent, demographic questions and baseline symptom, patient activation and quality of life outcome completion). Outcome measures included ESSPRI, Modified Fatigue Impact Scale, depression (VAS), anxiety (VAS), Sleep Condition Index, PAM-10 and ICECAP-A. Participants were randomised to an information-version (control) or full-version of Sjogo containing features supporting behaviour change. Users could engage with Sjogo as they wished and were asked to complete outcomes

Published
2022

16. Developing the FEEDS toolkit of parent-delivered interventions for eating, drinking and swallowing difficulties in young children with neurodisability: findings from a Delphi survey and stakeholder consultation workshops

Author

Taylor, Helen, primary, Pennington, Lindsay, additional, Morris, Christopher, additional, Craig, Dawn, additional, McConachie, Helen, additional, Cadwgan, Jill, additional, Sellers, Diane, additional, Andrew, Morag, additional, Smith, Johanna, additional, Garland, Deborah, additional, McColl, Elaine, additional, Buswell, Charlotte, additional, Thomas, Julian, additional, Colver, Allan, additional, and Parr, Jeremy, additional

Published
2022
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23. Additional file 8 of A collaborative approach to develop an intervention to strengthen health visitors’ role in prevention of excess weight gain in children

Author

Ray, Devashish, Sniehotta, Falko, McColl, Elaine, Ells, Louisa, O’Neill, Gill, and McCabe, Karen

Abstract

Additional file 8. a. Findings of the rating of importance and acceptability of 13 BCTs by workshop participants. b. Findings of the rating of the importance and acceptability of 5 BCTs by workshop participants.

Published
2022
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28. The Effectiveness and Cost-Effectiveness of Screening and Brief Alcohol Intervention to Reduce Alcohol Consumption in Young People in the High School Setting: A Pragmatic Randomized Controlled Trial (SIPS JR-HIGH)

Author

Coulton, Simon, primary, Giles, Emma L, additional, McGeechan, Grant J, additional, Deluca, Paolo, additional, Drummond, Colin, additional, Howel, Denise, additional, Kaner, Eileen, additional, McColl, Elaine, additional, McGovern, Ruth, additional, Scott, Stephanie, additional, Sumnall, Harry, additional, Vale, Luke, additional, Albani, Viviana, additional, Boniface, Sadie, additional, Ferguson, Jennifer, additional, Gilvarry, Eilish, additional, Hendrie, Nadine, additional, Howe, Nicola, additional, Ramsay, Amy, additional, and Newbury-Birch, Dorothy, additional

Published
2022
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31. Health related quality of life in young, steroid-naïve boys with Duchenne muscular dystrophy

Author

Campbell, Craig, primary, McColl, Elaine, additional, McDermott, Michael P., additional, Martens, William B., additional, Guglieri, Michela, additional, Griggs, Robert C., additional, Straub, Volker, additional, Childs, Anne-Marie, additional, Ciafaloni, Emma, additional, Shieh, Perry B., additional, Spinty, Stefan, additional, Butterfield, Russell J., additional, Horrocks, Iain, additional, Roper, Helen, additional, Maggi, Lorenzo, additional, Baranello, Giovanni, additional, Flanigan, Kevin M., additional, Kuntz, Nancy L., additional, Manzur, Adnan Y., additional, Darras, Basil T., additional, Kang, Peter, additional, Mah, Jean K., additional, Mongini, Tiziana, additional, Ricci, Federica, additional, Morrison, Leslie, additional, Krzesniak-Swinarska, Monika, additional, von der Hagen, Maja, additional, Finkel, Richard S., additional, Kumar, Ashutosh, additional, Wicklund, Matthew, additional, McDonald, Craig M., additional, Henricson, Erik K., additional, Schara-Schmidt, Ulrike, additional, Wilichowski, Ekkehard, additional, Barohn, Richard J., additional, Statland, Jeffrey, additional, Kirschner, Janbernd, additional, Vita, Giuseppe, additional, Vita, Gian Luca, additional, Howard, James F., additional, Hughes, Imelda, additional, McMillan, Hugh J., additional, Pegoraro, Elena, additional, Bello, Luca, additional, Burnette, W. Bryan, additional, Thangarajh, Mathula, additional, and Chang, Taeun, additional

Published
2021
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32. Ondansetron and metoclopramide as second-line antiemetics in women with nausea and vomiting in pregnancy: the EMPOWER pilot factorial RCT

Author

Robson, Stephen, primary, McParlin, Catherine, additional, Mossop, Helen, additional, Lie, Mabel, additional, Fernandez-Garcia, Cristina, additional, Howel, Denise, additional, Graham, Ruth, additional, Ternent, Laura, additional, Steel, Alison, additional, Goudie, Nicola, additional, Nadeem, Afnan, additional, Phillipson, Julia, additional, Shehmar, Manjeet, additional, Simpson, Nigel, additional, Tuffnell, Derek, additional, Campbell, Ian, additional, Williams, Rew, additional, O’Hara, Margaret E, additional, McColl, Elaine, additional, and Nelson-Piercy, Catherine, additional

Published
2021
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33. Effect of Different Corticosteroid Dosing Regimens on Clinical Outcomes in Boys With Duchenne Muscular Dystrophy: A Randomized Clinical Trial.

Author

Guglieri, Michela, Bushby, Kate, McDermott, Michael P., Hart, Kimberly A., Tawil, Rabi, Martens, William B., Herr, Barbara E., McColl, Elaine, Speed, Chris, Wilkinson, Jennifer, Kirschner, Janbernd, King, Wendy M., Eagle, Michelle, Brown, Mary W., Willis, Tracey, Griggs, Robert C., Straub, Volker, van Ruiten, Henriette, Childs, Anne-Marie, and Ciafaloni, Emma

Subjects
GLUCOCORTICOIDS, RESEARCH, STEROIDS, RESEARCH methodology, EVALUATION research, DUCHENNE muscular dystrophy, COMPARATIVE studies, RANDOMIZED controlled trials, RESEARCH funding, QUESTIONNAIRES, PREDNISONE
Abstract

Importance: Corticosteroids improve strength and function in boys with Duchenne muscular dystrophy. However, there is uncertainty regarding the optimum regimen and dosage.Objective: To compare efficacy and adverse effects of the 3 most frequently prescribed corticosteroid regimens in boys with Duchenne muscular dystrophy.Design, Setting, and Participants: Double-blind, parallel-group randomized clinical trial including 196 boys aged 4 to 7 years with Duchenne muscular dystrophy who had not previously been treated with corticosteroids; enrollment occurred between January 30, 2013, and September 17, 2016, at 32 clinic sites in 5 countries. The boys were assessed for 3 years (last participant visit on October 16, 2019).Interventions: Participants were randomized to daily prednisone (0.75 mg/kg) (n = 65), daily deflazacort (0.90 mg/kg) (n = 65), or intermittent prednisone (0.75 mg/kg for 10 days on and then 10 days off) (n = 66).Main Outcomes and Measures: The global primary outcome comprised 3 end points: rise from the floor velocity (in rise/seconds), forced vital capacity (in liters), and participant or parent global satisfaction with treatment measured by the Treatment Satisfaction Questionnaire for Medication (TSQM; score range, 0 to 100), each averaged across all study visits after baseline. Pairwise group comparisons used a Bonferroni-adjusted significance level of .017.Results: Among the 196 boys randomized (mean age, 5.8 years [SD, 1.0 years]), 164 (84%) completed the trial. Both daily prednisone and daily deflazacort were more effective than intermittent prednisone for the primary outcome (P < .001 for daily prednisone vs intermittent prednisone using a global test; P = .017 for daily deflazacort vs intermittent prednisone using a global test) and the daily regimens did not differ significantly (P = .38 for daily prednisone vs daily deflazacort using a global test). The between-group differences were principally attributable to rise from the floor velocity (0.06 rise/s [98.3% CI, 0.03 to 0.08 rise/s] for daily prednisone vs intermittent prednisone [P = .003]; 0.06 rise/s [98.3% CI, 0.03 to 0.09 rise/s] for daily deflazacort vs intermittent prednisone [P = .017]; and -0.004 rise/s [98.3% CI, -0.03 to 0.02 rise/s] for daily prednisone vs daily deflazacort [P = .75]). The pairwise comparisons for forced vital capacity and TSQM global satisfaction subscale score were not statistically significant. The most common adverse events were abnormal behavior (22 [34%] in the daily prednisone group, 25 [38%] in the daily deflazacort group, and 24 [36%] in the intermittent prednisone group), upper respiratory tract infection (24 [37%], 19 [29%], and 24 [36%], respectively), and vomiting (19 [29%], 17 [26%], and 15 [23%]).Conclusions and Relevance: Among patients with Duchenne muscular dystrophy, treatment with daily prednisone or daily deflazacort, compared with intermittent prednisone alternating 10 days on and 10 days off, resulted in significant improvement over 3 years in a composite outcome comprising measures of motor function, pulmonary function, and satisfaction with treatment; there was no significant difference between the 2 daily corticosteroid regimens. The findings support the use of a daily corticosteroid regimen over the intermittent prednisone regimen tested in this study as initial treatment for boys with Duchenne muscular dystrophy.Trial Registration: ClinicalTrials.gov Identifier: NCT01603407. [ABSTRACT FROM AUTHOR]

Published
2022
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34. Effectiveness and Cost-Effectiveness of Screening and Brief Alcohol Intervention to Reduce Alcohol Consumption in Young People in the High School Setting: A Pragmatic Randomized Controlled Trial (SIPS JR-HIGH).

Author

Coulton, Simon, Giles, Emma L, McGeechan, Grant J, Deluca, Paolo, Drummond, Colin, Howel, Denise, Kaner, Eileen, McColl, Elaine, McGovern, Ruth, Scott, Stephanie, Sumnall, Harry, Vale, Luke, Albani, Viviana, Boniface, Sadie, Ferguson, Jennifer, Gilvarry, Eilish, Hendrie, Nadine, Howe, Nicola, Ramsay, Amy, and Newbury-Birch, Dorothy

Subjects
PILOT projects, CLUSTER sampling, RESEARCH, CONFIDENCE intervals, ALCOHOL-induced disorders, MULTIPLE regression analysis, MEDICAL screening, TREATMENT effectiveness, RANDOMIZED controlled trials, COMPARATIVE studies, ALCOHOL drinking, COST effectiveness, RESEARCH funding, DATA analysis software, LOGISTIC regression analysis, HIGH school students, LONGITUDINAL method, SECONDARY analysis
Abstract

The article presents the discussion on Chief Medical Officer for England recommending that young people remaining alcohol free until 18 years of age. Topics include highest levels of drinking among adolescents and the North East England being one of the highest levels of adolescent alcohol consumption in the UK; and exploring the relationship between alcohol use during adolescence and negative consequences in adulthood.

Published
2022
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