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Your search keyword '"Mano, Yohei"' showing total 15 results
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15 results on '"Mano, Yohei"'

8. A new scoring system with simple preoperative parameters as predictors of early recurrence of pancreatic ductal adenocarcinoma

Author

Shimagaki, Tomonari, primary, Sugimachi, Keishi, additional, Mano, Yohei, additional, Tomino, Takahiro, additional, Onishi, Emi, additional, Nakashima, Yuichiro, additional, Sugiyama, Masahiko, additional, Yamamoto, Manabu, additional, Morita, Masaru, additional, Shimokawa, Mototsugu, additional, Yoshizumi, Tomoharu, additional, and Toh, Yasushi, additional

Published
2023
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10. Prognostic Significance of Preoperative Nutritional Assessment in Elderly Patients who Underwent Laparoscopic Gastrectomy for Stage I-III Gastric Cancer

Author

UEHARA, HIDEO, primary, OTA, MITSUHIKO, additional, YAMAMOTO, MANABU, additional, NAKANOKO, TOMONORI, additional, SHIN, YUKI, additional, SHIOKAWA, KEIICHI, additional, FUJIMOTO, YOSHIAKI, additional, NAKASHIMA, YUICHIRO, additional, SUGIYAMA, MASAHIKO, additional, ONISHI, EMI, additional, SHIMAGAKI, TOMONARI, additional, MANO, YOHEI, additional, SUGIMACHI, KEISHI, additional, MORITA, MASARU, additional, and TOH, YASUSHI, additional

Published
2023
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11. Persistent epigenetic alterations in transcription factors after a sustained virological response in hepatocellular carcinoma

Author

Sugimachi, Keishi, primary, Araki, Hiromitsu, additional, Saito, Hideyuki, additional, Masuda, Takaaki, additional, Miura, Fumihito, additional, Inoue, Kentaro, additional, Shimagaki, Tomonari, additional, Mano, Yohei, additional, Iguchi, Tomohiro, additional, Morita, Masaru, additional, Toh, Yasushi, additional, Yoshizumi, Tomoharu, additional, Ito, Takashi, additional, and Mimori, Koshi, additional

Published
2022
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12. Prognostic significance of preoperative nutritional assessment in elderly patients who underwent laparoscopic gastrectomy for stage I–III gastric cancer

Author

Uehara, Hideo, primary, Ota, Mitsuhiko, additional, Yamamoto, Manabu, additional, Nakanoko, Tomonori, additional, Shin, Yuki, additional, Shiokawa, Keiichi, additional, Fujimoto, Yoshiaki, additional, Nakashima, Yuichiro, additional, Sugiyama, Masahiko, additional, Onishi, Emi, additional, Shimagaki, Tomonari, additional, Mano, Yohei, additional, Sugimachi, Keishi, additional, Morita, Masaru, additional, and Toh, Yasushi, additional

Published
2022
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13. Simple systemic index associated with oxaliplatin‐induced liver damage can be a novel biomarker to predict prognosis after resection of colorectal liver metastasis

Author

Shimagaki, Tomonari, primary, Sugimachi, Keishi, additional, Mano, Yohei, additional, Onishi, Emi, additional, Iguchi, Tomohiro, additional, Uehara, Hideo, additional, Sugiyama, Masahiko, additional, Yamamoto, Manabu, additional, Morita, Masaru, additional, and Toh, Yasushi, additional

Published
2022
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14. Indications for conversion hepatectomy for initially unresectable colorectal cancer with liver metastasis

Author

Sugiyama, Masahiko, primary, Uehara, Hideo, additional, Shin, Yuki, additional, Shiokawa, Keiichi, additional, Fujimoto, Yoshiaki, additional, Mano, Yohei, additional, Komoda, Masato, additional, Nakashima, Yuichiro, additional, Sugimachi, Keishi, additional, Yamamoto, Manabu, additional, Morita, Masaru, additional, and Toh, Yasushi, additional

Published
2021
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15. Prognostic Impact of Vessels that Encapsulate Tumor Cluster (VETC) in Patients who Underwent Liver Transplantation for Hepatocellular Carcinoma.

Author

Kawasaki, Junji, Toshima, Takeo, Yoshizumi, Tomoharu, Itoh, Shinji, Mano, Yohei, Wang, Huanlin, Iseda, Norifumi, Harada, Noboru, Oda, Yoshinao, and Mori, Masaki

Abstract

Background: There is limited published information about prognostic value of vessels that encapsulate tumor cluster (VETC) based on their involvement with immune cells in hepatocellular carcinoma (HCC). Our goal was to evaluate prognostic impact of VETC in patients who underwent living-donor liver transplantation (LDLT) for HCC, focusing on the involvement of VETC with immune status in tumor microenvironment (TME). Methods: Using a database of 150 patients who underwent LDLT for HCC, immunohistochemical staining of CD34 for VETC, angiopoietin-2 (Ang-2), CD3, and CD68, was reviewed with patients' clinicopathological factors. Results: A strong correlation between VETC pattern and malignant potential in HCC was observed; larger tumor size (P < 0.001), more numbers of tumors (P = 0.003), higher α-fetoprotein levels (P = 0.001), higher des-γ-carboxy prothrombin levels (P = 0.022), microvascular invasion (P < 0.001), and poor differentiation (P = 0.010). Overall survival (OS) of patients with VETC(+) was significantly lower than those with VETC(−) (P = 0.021; 5-year OS rates, 72.0% vs. 87.1%). Furthermore, the ratio of CD3(+) cells was significantly lower in VETC(+) group (P = 0.001), indicating that VETC activity may be strongly correlated with lymphocyte activity. Moreover, combination status of VETC(+)/CD3low was an independent risk factor for mortality (hazard ratio 2.760, 95% confidence interval 1.183–6.439, P = 0.019). Additionally, the combination of VETC expression with immune status (low CD3 levels) enabled further classification of patients based on their clinical outcome. Conclusions: Our results show the prognostic impact of VETC expression, tumor-infiltrating lymphocytes (TILs), and their combination in the setting of LDLT for HCC, which can be a novel prognostic biomarker for mortality after LDLT. [ABSTRACT FROM AUTHOR]

Published
2021
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