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20 results on '"Maisey, Nick"'

2. Association of dynamic contrast-enhanced MRI and 18F-Fluorodeoxyglucose PET/CT parameters with neoadjuvant therapy response and survival in esophagogastric cancer

Author

Baker, C.R., Bell, J., Chang, F., Chicklore, S., Cominos, M., Coombes, A., Dunn, J.N., George, S., Gill-Barman, B., Gossage, J.A., Gourtsoyianni, S., Green, A., Griffin, N., Hill, M., Hynes, O., Iezzi, C., Jacques, A., Kelly, M., Mahadeva, U., McEwan, R., Meenan, J., Neji, R., Ngan, S., Padormo, F., Qureshi, A., Reyhani, A., Sharkey, A.R., Spence, J., Subesinghe, M., Tham, G., Waters, J., Zeki, S.S., Withey, Samuel J., Owczarczyk, Kasia, Grzeda, Mariusz T., Yip, Connie, Deere, Harriet, Green, Mike, Maisey, Nick, Davies, Andrew R., Cook, Gary J., and Goh, Vicky

Published
2023
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4. Association of dynamic contrast-enhanced MRI and 18F-Fluorodeoxyglucose PET/CT parameters with neoadjuvant therapy response and survival in esophagogastric cancer

Author

Withey, Samuel J., primary, Owczarczyk, Kasia, additional, Grzeda, Mariusz T., additional, Yip, Connie, additional, Deere, Harriet, additional, Green, Mike, additional, Maisey, Nick, additional, Davies, Andrew R., additional, Cook, Gary J., additional, Goh, Vicky, additional, Baker, C.R., additional, Bell, J., additional, Chang, F., additional, Chicklore, S., additional, Cominos, M., additional, Coombes, A., additional, Dunn, J.N., additional, George, S., additional, Gill-Barman, B., additional, Gossage, J.A., additional, Gourtsoyianni, S., additional, Green, A., additional, Griffin, N., additional, Hill, M., additional, Hynes, O., additional, Iezzi, C., additional, Jacques, A., additional, Kelly, M., additional, Mahadeva, U., additional, McEwan, R., additional, Meenan, J., additional, Neji, R., additional, Ngan, S., additional, Padormo, F., additional, Qureshi, A., additional, Reyhani, A., additional, Sharkey, A.R., additional, Spence, J., additional, Subesinghe, M., additional, Tham, G., additional, Waters, J., additional, and Zeki, S.S., additional

Published
2023
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7. Prehabilitation exercise before oesophagectomy: long-term follow-up of patients declining/withdrawing from the program

Author

Knight, William, primary, Moore, Jonathan L, additional, Whyte, Greg P, additional, Zylstra, Janine, additional, Lane, Andrew M, additional, Pate, James, additional, Gervais-Andre, Louise, additional, Maisey, Nick, additional, Hill, Mark, additional, Tham, Gemma, additional, Lagergren, Jesper, additional, Kelly, Mark, additional, Baker, Cara, additional, Van Hemelrijck, Mieke, additional, Goh, Vicky, additional, Gossage, James, additional, Browning, Mike, additional, and Davies, Andrew R, additional

Published
2023
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8. Pathologic Lymph Node Regression After Neoadjuvant Chemotherapy Predicts Recurrence and Survival in Esophageal Adenocarcinoma: A Multicenter Study in the United Kingdom.

Author

Moore, Jonathan L., Green, Michael, Santaolalla, Aida, Deere, Harriet, Evans, Richard P.T., Elshafie, Mona, Lavery, Anita, McManus, Damian T., McGuigan, Andrew, Douglas, Rosalie, Horne, Joanne, Walker, Robert, Mir, Hira, Terlizzo, Monica, Kamarajah, Sivesh K., Van Hemelrijck, Mieke, Maisey, Nick, Sita-Lumsden, Ailsa, Ngan, Sarah, and Kelly, Mark

Published
2023
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9. OGC P20 Metabolic tumour and nodal response to neoadjuvant chemotherapy on FDG PET-CT as a predictor of pathological response and survival in patients undergoing surgical resection for locally advanced oesophageal adenocarcinoma

Author

Moore, Jonathan, primary, Subesinghe, Manil, additional, Santaolalla, Aida, additional, Green, Michael, additional, Deere, Harriet, additional, Van Hemelrijck, Mieke, additional, Lagergren, Jesper, additional, Chicklore, Sugama, additional, Maisey, Nick, additional, Gossage, James, additional, Kelly, Mark, additional, Baker, Cara, additional, and Davies, Andrew, additional

Published
2022
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10. OGC O02 The prognostic effect of pathological lymph node regression after neoadjuvant chemotherapy for oesophageal adenocarcinoma – a multicentre study

Author

Moore, Jonathan, primary, Green, Michael, additional, Deere, Harriet, additional, Santaolalla, Aida, additional, Evans, Richard, additional, Elshafie, Mona, additional, Lavery, Anita, additional, McGuigan, Andrew, additional, McManus, Damian, additional, Horne, Joanne, additional, Walker, Robert, additional, Mir, Hira, additional, Terlizzo, Monica, additional, Kamarajah, Sivesh, additional, Van Hemelrijck, Mieke, additional, Maisey, Nick, additional, Lumsden, Ailsa, additional, Ngan, Sarah, additional, Kelly, Mark, additional, Baker, Cara, additional, Kumar, Sacheen, additional, Lagergren, Jesper, additional, Allum, William, additional, Gossage, James, additional, Griffiths, Ewan, additional, Grabsch, Heike, additional, Turkington, Richard, additional, Underwood, Tim, additional, Smyth, Elizabeth, additional, Fitzgerald, Rebecca, additional, Cunningham, David, additional, and Davies, Andrew, additional

Published
2022
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11. 568. THE PROGNOSTIC EFFECT OF PATHOLOGICAL LYMPH NODE REGRESSION AFTER NEOADJUVANT CHEMOTHERAPY FOR OESOPHAGEAL ADENOCARCINOMA – A MULTICENTRE STUDY

Author

Moore, Jonathan, primary, Green, Michael, additional, Van Hemelrijck, Mieke, additional, Deere, Harriet, additional, Evans, Richard PT, additional, Elshafie, Mona, additional, Lavery, Anita, additional, McGuigan, Andrew, additional, Douglas, Rosalie, additional, Mcmanus, Damian, additional, Horne, Joanne, additional, Walker, Robert, additional, Mir, Hira, additional, Terlizzo, Monica, additional, Kamarajah, Sivesh K, additional, Santaolalla, Aida, additional, Maisey, Nick, additional, Lumsden, Ailsa, additional, Ngan, Sarah, additional, Kelly, Mark, additional, Baker, Cara R, additional, Kumar, Sacheen, additional, Lagergren, Jesper, additional, Allum, William H, additional, Gossage, James A, additional, Griffiths, Ewan, additional, Grabsch, Heike I, additional, Turkington, Richard C, additional, Underwood, Tim, additional, Smyth, Elizabeth, additional, Fitzgerald, Rebecca, additional, Cunningham, David, additional, and Davies, Andrew R, additional

Published
2022
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12. 354. THE PARADIGM OF INACCURACIES IN STAGING EARLY OESOPHAGEAL ADENOCARCINOMA

Author

Reyhani, Arasteh, primary, Gimson, Eliza, additional, Baker, Cara, additional, Kelly, Mark, additional, Maisey, Nick, additional, Meenan, John, additional, Subesinghe, Manil, additional, Hill, Mark, additional, Lagergren, Jesper, additional, Gossage, James, additional, Zeki, Sebastian, additional, Dunn, Jason, additional, and Davies, Andrew, additional

Published
2022
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13. 577. FDG PT-CT METABOLIC TUMOUR AND NODAL RESPONSE AS A PREDICTOR OF PATHOLOGICAL RESPONSE AND SURVIVAL IN PATIENTS WITH OESOPHAGEAL ADENOCARCINOMA

Author

Moore, Jonathan, primary, Subesinghe, Manil, additional, Santaolalla, Aida, additional, Green, Michael, additional, Deere, Harriet, additional, Van Hemelrijck, Mieke, additional, Lagergren, Jesper, additional, Chicklore, Sugama, additional, Maisey, Nick, additional, Kelly, Mark, additional, Gossage, James A, additional, Baker, Cara R, additional, and Davies, Andrew R, additional

Published
2022
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14. Effect of peri-operative chemotherapy regimen on survival in the treatment of locally advanced oesophago-gastric adenocarcinoma – A comparison of the FLOT and ‘MAGIC’ regimens

Author

Moore, Jonathan L., primary, Kumar, Sacheen, additional, Santaolalla, Aida, additional, Patel, Pranav H., additional, Kapiris, Matthaios, additional, Van Hemelrijck, Mieke, additional, Maisey, Nick, additional, Hill, Mark, additional, Lagergren, Jesper, additional, Gossage, James A., additional, Kelly, Mark, additional, Chaudry, Asif, additional, Allum, William H., additional, Baker, Cara R., additional, Cunningham, David, additional, Davies, Andrew R., additional, Jacques, A., additional, Griffin, N., additional, Goh, V., additional, Ngan, S., additional, Owczarczyk, K., additional, Lumsden, A., additional, Qureshi, A., additional, Deere, H., additional, Green, M., additional, Chang, F., additional, Mahadeva, U., additional, Gill-Barman, B., additional, George, S., additional, Ong, M., additional, Waters, J., additional, Cominos, M., additional, Sevitt, T., additional, Hynes, O., additional, Tham, G., additional, Bott, R.K., additional, Dunn, J.M., additional, and Zeki, S.S., additional

Published
2022
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15. Exercise prehabilitation during neoadjuvant chemotherapy may enhance tumour regression in oesophageal cancer: results from a prospective non-randomised trial

Author

Zylstra, Janine, primary, Whyte, Greg P, additional, Beckmann, Kerri, additional, Pate, James, additional, Santaolalla, Aida, additional, Gervais-Andre, Louise, additional, Russell, Beth, additional, Maisey, Nick, additional, Waters, Justin, additional, Tham, Gemma, additional, Lagergren, Jesper, additional, Green, Michael, additional, Kelly, Mark, additional, Baker, Cara, additional, Van Hemelrijck, Mieke, additional, Goh, Vicky, additional, Gossage, James, additional, Browning, Mike, additional, and Davies, Andrew, additional

Published
2022
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17. Predicting response to neoadjuvant chemotherapy in patients with oesophageal adenocarcinoma

Author

Bott, Rebecca K., primary, George, Gincy, additional, McEwen, Ricardo, additional, Zylstra, Janine, additional, Knight, William R. C., additional, Baker, Cara R., additional, Kelly, Mark, additional, Griffin, Nyree, additional, McAddy, Naami, additional, Maisey, Nick, additional, Van Hemelrijck, Mieke, additional, Gossage, James A., additional, Lagergren, Jesper, additional, and Davies, Andrew R., additional

Published
2021
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18. 646 PREDICTING RESPONSE TO NEOADJUVANT CHEMOTHERAPY IN PATIENTS WITH OESOPHAGEAL ADENOCARCINOMA

Author

Bott, Rebecca, primary, George, Gincy, additional, McEwen, Ricardo, additional, Zylstra, Janine, additional, Knight, William, additional, Baker, Cara, additional, Kelly, Mark, additional, Griffin, Nyree, additional, Mcaddy, Naami, additional, Maisey, Nick, additional, Van Hemelrijck, Mieke, additional, Gossage, James, additional, Lagergren, Jesper, additional, and Davies, Andrew, additional

Published
2021
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20. Association of dynamic contrast-enhanced MRI and 18 F-Fluorodeoxyglucose PET/CT parameters with neoadjuvant therapy response and survival in esophagogastric cancer.

Author

Withey SJ, Owczarczyk K, Grzeda MT, Yip C, Deere H, Green M, Maisey N, Davies AR, Cook GJ, and Goh V

Subjects
Male, Humans, Aged, Fluorodeoxyglucose F18 therapeutic use, Positron Emission Tomography Computed Tomography methods, Neoadjuvant Therapy methods, Radiopharmaceuticals, Prospective Studies, Magnetic Resonance Imaging, Esophageal Neoplasms diagnostic imaging, Esophageal Neoplasms therapy, Esophageal Neoplasms metabolism, Stomach Neoplasms diagnostic imaging, Stomach Neoplasms therapy
Abstract

Introduction: Better predictive markers are needed to deliver individualized care for patients with primary esophagogastric cancer. This exploratory study aimed to assess whether pre-treatment imaging parameters from dynamic contrast-enhanced MRI and 18 F-fluorodeoxyglucose ( 18 F-FDG) PET/CT are associated with response to neoadjuvant therapy or outcome., Materials and Methods: Following ethical approval and informed consent, prospective participants underwent dynamic contrast-enhanced MRI and 18 F-FDG PET/CT prior to neoadjuvant chemotherapy/chemoradiotherapy ± surgery. Vascular dynamic contrast-enhanced MRI and metabolic 18 F-FDG PET parameters were compared by tumor characteristics using Mann Whitney U test and with pathological response (Mandard tumor regression grade), recurrence-free and overall survival using logistic regression modelling, adjusting for predefined clinical variables., Results: 39 of 47 recruited participants (30 males; median age 65 years, IQR: 54, 72 years) were included in the final analysis. The tumor vascular-metabolic ratio was higher in patients remaining node positive following neoadjuvant therapy (median tumor peak enhancement/SUV max ratio: 0.052 vs. 0.023, p = 0.02). In multivariable analysis adjusted for age, gender, pre-treatment tumor and nodal stage, peak enhancement (highest gadolinium concentration value prior to contrast washout) was associated with pathological tumor regression grade. The odds of response decreased by 5% for each 0.01 unit increase (OR 0.95; 95% CI: 0.90, 1.00, p = 0.04). No 18 F-FDG PET/CT parameters were predictive of pathological tumor response. No relationships between pre-treatment imaging and survival were identified., Conclusion: Pre-treatment esophagogastric tumor vascular and metabolic parameters may provide additional information in assessing response to neoadjuvant therapy., (Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.)

Published
2023
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