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The human–animal relationship and its benefits have been a popular issue in recent decades. This study focuses on the dog as a paradigmatic example of this complex bond. The relationship between human and dog evolved over thousands of years through the domestication process. During this period, climatic, cultural, geographical and social changes have had a direct impact on this bond. Dogs have a remarkable capacity to play a variety of roles that mirror the evolution of human societies. Subsequently, questions arise regarding the important and symbolic roles that canines played in ancient cultures, religions and mythological traditions. Specifically, how have these roles changed through history? This research aimed to explore the socio‐economic aspects of the human–dog relationship, spanning from ancient civilizations to modern societies. Through a systematic search methodology, this investigation seeks to provide insights into the dynamics of the complex human–dog relationship, including historical backgrounds, socio‐cultural dynamics, economic implications and associated challenges. Additionally, the present study addresses the environmental concerns that emerge alongside rising stray dog populations. This research emphasizes the importance of strategies to balance the benefits of this coexistence that promote human and animal welfare. [ABSTRACT FROM AUTHOR]

Motifs have critical impacts on the behavioral and structural characteristics of RNA sequences. Understanding and predicting the functionalities and interactions of an RNA sequence requires discovering and identifying its motifs. Due to the importance of motif discovery in bioinformatics, a significant corpus of techniques and algorithms have been proposed, each of which has various advantages and limitations and hence, are suitable for specific applications. To understand these techniques and algorithms, compare them, and choose the most suitable one for a particular application scenario, it is crucial to have a clear understanding of the different vital aspects that characterize these algorithms. The lack of such a framework to study these aspects is a serious existing challenge in the literature that needs further investigation. In this paper, we propose a taxonomy and a framework to address this issue. We define the concept of motif discovery process and three aspects that characterize such a process, which are motif type, discovery technique, and application. We then study the literature and classify the existing approaches along with these aspects. This will give the reader a broader view and more precise understanding of what these techniques and algorithms do, how they do it, and what is the most suitable application for each of them. We then present the possible gaps and challenges foreseen to be the future directions of the area. [ABSTRACT FROM AUTHOR]

Lysozyme activity is one of the nonspecific immunity parameters measured by changing the amount of adsorption at different times. The objective of the present study was to compare five non-linear models including Gompertz, Richards, Logistic, Lopez, and Weilbull to describe the cumulative plasma lysozyme activity in quails. In total 1364 plasma samples (1004 females and 360 males) were collected and the cumulative lysozyme activity was calculated by turbidimetric method assay in Micrococcus luteus. The goodness-of-fit of models was compared according to different criteria of Maximum loglikelihood, Akaike information criterion, Mean square error, and Bayesian information criterion. The results showed that the Gompertz model was the best model for describing of decreasing cumulative pattern of lysozyme activity in female and male quails and provided satisfactory predictions of lysozyme activity at different times (30, 60, 90, 120, 150, 180, 210, 240, 270, 300 seconds). The parameters of all models were higher in females than males except for the k parameter which was greater in the males. Male quails had higher values for time and lysozyme activity than females at inflection points, whereas the absolute growth rate in 30, 150, and 300 seconds was predicted higher in female quails. In conclusion, the Gompertz model can be used accurately to evaluate cumulative lysozyme activity patterns in both sexes of quails. [ABSTRACT FROM AUTHOR]