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Your search keyword '"Mélodie Lucas"' showing total 2 results
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2 results on '"Mélodie Lucas"'

1. Deprived social status is associated with decreased use of oral chemotherapy in patients with metastatic colorectal cancer: A retrospective cohort study on administrative databases in a French University Hospital

Author

Gwendoline Gautier, Mélodie Lucas, Thomas Vermeulin, Frederic Di Fiore, and Veronique Merle

Subjects
colorectal cancer, deprivation, oral chemotherapy, patient care, Therapeutics. Pharmacology, RM1-950
Abstract

Abstract Factors associated with the choice of oral versus intravenous CT are not clearly established. Our purpose was to evaluate the influence of social status and home distance to hospital on the use of oral CT in patients with metastatic colorectal cancer (mCRC). This retrospective single‐center study included mCRC patients between 2011 and 2017. Patient social status was assessed by European Deprivation Index (EDI) and home distance to the hospital was calculated. Univariable and multivariable logistic regression analyses were performed. One hundred and seventy‐five mCRC patients were included, with 71 receiving oral CT. Most deprived patients received less oral CT (OR 0.5 [0.26, 0.96], p = .039). No association was found for road distance. Previous use of adjuvant oral CT was associated with oral CT in mCRC (OR 2.65 [1.06, 6.66], p = .038). Our results suggest that deprived social status is a factor associated with decreased use of oral CT in patients with mCRC. Clinical trial registration: no registration.

Published
2021
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2. Are patients living far from hospital at higher risk of late adjuvant chemotherapy for colon cancer?

Author

Thomas Vermeulin, Hana Lahbib, Mélodie Lucas, Pierre Czernichow, Florence Jusot, Frédéric Di Fiore, and Véronique Merle

Subjects
Cohort Studies, Pharmacology, Chemotherapy, Adjuvant, Colonic Neoplasms, Humans, Pharmacology (medical), Hospitals, Neoplasm Staging, Retrospective Studies
Abstract

Late adjuvant chemotherapy (aCT) administration after colectomy (56 d) is known to be associated with impaired prognosis. We aim to identify risk factors associated with late aCT, especially the travel time between patients' home and hospital.We performed a retrospective monocentre cohort study. Patients included had a colectomy for a stage III or high risk stage II colon cancer between 2009 and 2015 performed at a French university hospital. Risk factors for late aCT were identified using a fractional polynomial logistic regression.Ninety-four patients were included. The risk of late aCT was associated with travel time length, emergent colectomy, the need for scheduled care before aCT, and length of time between colectomy and postoperative multidisciplinary meeting advising aCT.Our study suggests that, in patients with colon cancer, factors unrelated to disease severity and complexity could be associated with a higher risk of late aCT.

Published
2022

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