Search

Effective glucose surveillance provides a strong guarantee for the high-quality development of human health. Au nanomaterials possess compelling applications in nonenzymatic electrochemical glucose biosensors owing to superior catalytic performances and intriguing biocompatibility properties. However, it has been a grand challenge to accurately control the architecture and composition of Au nanomaterials to optimize their optical, electronic, and magnetic properties for further improving the performance of electrocatalytic sensing. Herein, ultra-low content Bi-anchored Au aerogels are synthesized via a one-step reduction strategy. Benefiting from the unique structure of aerogels as well as the synergistic effect between Au and Bi, the optimized Au

In this study, a novel donor-acceptor conjugated polymer PDPPDTP was designed and synthesized by D-A polymerization using 2,6-di(trimethyltin)

Organic ligands can induce p–d orbital hybridization at the interface of CoFe LDH, resulting in a downshift of the d-band center of CoFe LDH and the optimization of the binding strength of intermediates during the OER.

The large-scale application of nanozymes remains a significant challenge owing to their unsatisfactory catalytic performances. Featuring a unique electronic structure and coordination environment, single-atom nanozymes provide great opportunities to vividly mimic the specific metal catalytic center of natural enzymes and achieve superior enzyme-like activity. In this study, the spin state engineering of Fe single-atom nanozymes (FeNC) is employed to enhance their peroxidase-like activity. Pd nanoclusters (Pd

With high activity and specificity to conduct catalysis under mild conditions, enzymes show great promise in many fields. However, they are not acclimatized to environments in practice after leaving the familiar biological conditions. Aiming at this issue, nanobiocatalysis, a fresh area integrating nanotechnology and enzymatic catalysis, is expected to design biocatalysis based on materials science. Specifically, nano-integrated biocatalysis and bio-inspired nanocatalysis are considered as two effective nanobiocatalytic systems to meet different design needs. Notably, both systems are not entirely separated, and the combination of both further sparks more possibilities. This review summarizes the type, construction, and function of nanobiocatalytic systems, analyzing the pros and cons of different strategies. Moreover, the corresponding applications in bioassay, biotherapy, and environmental remediation are highlighted. We hope that the advent of nanobiocatalysis will help in grasping the inherence of biocatalysis and propel biocatalytic applications.

The conventional cathodic electrochemiluminescence (ECL) always requires a more negative potential to trigger strong emission, which inevitably damages the bioactivity of targets and decreases the sensitivity and specificity. In this work, iron single-atom catalysts (Fe-N-C SACs) were employed as an efficient co-reaction accelerator for the first time to achieve the impressively cathodic emission of a luminol-H

Tris(bipyridine) ruthenium(II)-based luminophores have been well developed in the area of electrochemiluminescence, while their applications in chemiluminescence (CL) are rarely studied due to the poor luminous efficiency and complicated CL reaction. Herein, a novel tris(bipyridine) ruthenium(II)-based ternary CL system is proposed by introducing cobalt single atoms integrated with graphene-encapsulated cobalt nanoparticles (Co SAs/Co@C) and peroxymonosulfate (PMS) as advanced coreaction accelerator and promising coreactant, respectively. On the basis of the experimental results and density functional theory calculations, it is concluded that Co@C can synergistically modulate the adsorption behavior of PMS on Co SAs and then efficiently activate PMS to produce massive singlet oxygen for remarkable CL emission. Under the optimum conditions, the as-prepared CL biosensor exhibits a good linear range, excellent sensitivity, and selectivity, holding great potential for the practical detection of prostate-specific antigen in human serum.

The investigations on the generation, separation, and interfacial-redox-reaction processes of the photoinduced carriers are of paramount importance for realizing efficient photoelectrochemical (PEC) detection. However, the sluggish interfacial reactions of the photogenerated carriers, combined with the need for appropriate photoactive layers for sensing, remain challenges for the construction of advanced PEC platforms. Here, as a proof of concept, well-defined Fe single-atom catalysts (Fe SACs) were integrated on the surface of semiconductors, which amplified the PEC signals

Tremendous efforts have been made in developing single-atomic site catalysts (SASCs) for oxygen reduction reaction (ORR), which is regarded as a pivotal cornerstone in electrochemical energy conversion. However, SASCs for ORR have not been explored for electrochemical sensing. Herein, a template-sacrificed strategy is reported for the synthesis of atomically dispersed Ir SASCs, serving as a sensing platform to detect organophosphorus pesticides (OPs) with high sensitivity and selectivity. Owing to abundant Ir single-atom active sites, Ir SASCs show excellent ORR activity and stability in a neutral medium. It is found that the ORR activity of Ir SASCs can be inhibited by thiocholine, which is the hydrolysate of acetylthiocholine. After being integrated with acetylcholinesterase (AChE), the AChE-Ir SASC-based electrochemical sensor is established and shows a superior sensitivity, which shows a wide detection range of 0.5-500 ng mL

Photoelectrochemical (PEC) enzymatic biosensors integrate the excellent selectivity of enzymes and high sensitivity of PEC bioanalysis, while the shortcomings of high cost, poor stability, as well as tedious immobilization of natural enzymes on photoelectrodes, severely suppress their applications. AgCu@CuO aerogel-based photoelectrode material with both remarkable enzyme-like activities and outstanding photoelectric properties was innovatively designed and synthesized to evaluate the activity of xanthine oxidase with a wide linear detection range and a low limit of detection.

Developing effective electrocatalysts to achieve highly sensitive and selective detection of heavy metal ions is one of the challenges in the field of environmental monitoring. Herein, bismuth (Bi) metallene (Bi-ene) in atomic thickness is successfully synthesized and applied as a conceptual application in electrochemical sensors for the detection of lead ion (Pb

Lead selenide (PbSe) colloidal quantum dots (CQDs) are promising candidates for optoelectronic applications. To date, PbSe CQDs capped by halide ligands exhibit improved stability and solar cells using these CQDs as active layers have reported a remarkable power conversion efficiency (PCE) up to 10%. However, PbSe CQDs are more prone to oxidation, requiring delicate control over their processability and compromising their applications. Herein, an efficient strategy that addresses this issue by an in situ cation-exchange process is reported. This is achieved by a two-phase ligand exchange process where PbI

Cell-free enzymatic catalysis (CFEC) is emerging biotechnology that simulates biological transformations without living cells. However, the high cost of separation and preparation of the enzyme has hindered the practical application of the CFEC. Enzyme immobilization technologies using solid supports to stabilize enzymes have been regarded as an efficient strategy to address this issue. Nevertheless, the activity and stability of the immobilized enzymes are still crucial challenges for working in vitro. Herein, an enzyme immobilization platform is developed by using PtCu hydrogels coated with amorphous metallic-organic frameworks (MOFs) as multifunctional carriers to encapsulate horseradish peroxidase (HRP). Specifically, PtCu hydrogels acting as a "reservoir of metal ions" can interact with the immobilized enzyme and facilitate electron transfer, leading to the boosted enzyme catalytic performances. Furthermore, amorphous MOFs on the surface of PtCu hydrogels serve as an "armor" to protect the internal enzymes from various perturbation environments. The resultant enzyme immobilization platform (PtCu@HRP@ZIF-8) not only shows an approximately 2.4-fold enhanced activity compared with free enzyme but also exhibits improved stability against harsh conditions. The PtCu@HRP@ZIF-8-based biosensor is constructed for sensitive sensing of organophosphorus pesticides (OPs). The proposed biosensor exhibits a favorable linear relationship with the concentration of paraoxon-ethyl from 6 to 800 ng/mL, with a low detection limit of 1.8 ng/mL. This work reveals the promising potential of our proposed enzyme immobilization platform in practical applications.

Metal-organic framework (MOF)-based materials are regarded as potential electrocatalysts for oxygen evolution reaction (OER) resulting from the abundant pore structures, large surface area and atomically dispersed metal centers, while their coordinately saturated metal nodes are inert to electrocatalysis. In this work, creating active sites while accelerating charge transport is proposed to improve the OER properties of MOF-derived layered double hydroxides (MLDH). By using multifunctional Ti3C2 MXene as support and post-treating MOF with an etching-coprecipitating process, the resultant CoFe MLDH/Ti3C2 exhibits prominent OER performance with ultralow overpotentials of only 170 and 238 mV to achieve the current density of 10 and 100 mA/cm2, respectively. In addition, the experimental and theoretical calculation results prove the strong electronic interaction between CoFe MLDH and Ti3C2 MXene could modulate the binding strength of intermediates for OER. This work gives a direction to prepare MOF-based efficient catalysts and enhance the intrinsic activity of (oxy)hydroxide-based catalysts.