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Your search keyword '"Liu, Zhudong"' showing total 17 results
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17 results on '"Liu, Zhudong"'

9. Additional file 4 of Comparative genomic analysis of Citrobacter sp. XT1-2-2 reveals insights into the molecular mechanism of microbial immobilization of heavy metals

Author

Shan, Shiping, Cheng, Wei, Li, Yilu, Zhang, Min, Liu, Zhudong, Wang, Yushuang, Wei, Xiaowu, Fu, Zujiao, Wu, Shandong, Du, Dongxia, and Guo, Zhaohui

Abstract

Additional file 4: Supplementary Table S4. Basic information of sulfate reduction pathwaygenes on Chromosomal and BLASTP analysis in swissprot database.

Published
2023
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10. Additional file 7 of Comparative genomic analysis of Citrobacter sp. XT1-2-2 reveals insights into the molecular mechanism of microbial immobilization of heavy metals

Author

Shan, Shiping, Cheng, Wei, Li, Yilu, Zhang, Min, Liu, Zhudong, Wang, Yushuang, Wei, Xiaowu, Fu, Zujiao, Wu, Shandong, Du, Dongxia, and Guo, Zhaohui

Abstract

Additional file 7: Supplementary Table S7. Basic information of the Citrobacter species used for the pan genome analysis.

Published
2023
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11. Additional file 5 of Comparative genomic analysis of Citrobacter sp. XT1-2-2 reveals insights into the molecular mechanism of microbial immobilization of heavy metals

Author

Shan, Shiping, Cheng, Wei, Li, Yilu, Zhang, Min, Liu, Zhudong, Wang, Yushuang, Wei, Xiaowu, Fu, Zujiao, Wu, Shandong, Du, Dongxia, and Guo, Zhaohui

Abstract

Additional file 5: Supplementary Table S5. Basic information of heavy metal resistancegenes on Chromosomal and BLASTP analysis in swissprot database.

Published
2023
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15. Comparative Proteomics Reveals the Effect of the Transcriptional Regulator Sp13016 on Butenyl-Spinosyn Biosynthesis in Saccharopolyspora pogona

Author

Tang, Jianli, primary, He, Haocheng, additional, Li, Yunlong, additional, Liu, Zhudong, additional, Xia, Ziyuan, additional, Cao, Li, additional, Zhu, Zirong, additional, Shuai, Ling, additional, Liu, Yang, additional, Wan, Qianqian, additional, Luo, Yuewen, additional, Zhang, Youming, additional, Rang, Jie, additional, and Xia, Liqiu, additional

Published
2021
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16. Flaviolin-Like Gene Cluster Deletion Optimized the Butenyl-Spinosyn Biosynthesis Route in Saccharopolyspora pogona

Author

He, Haocheng, primary, Tang, Jianli, additional, Chen, Jianming, additional, Hu, Jinjuan, additional, Zhu, Zirong, additional, Liu, Yang, additional, Shuai, Ling, additional, Cao, Li, additional, Liu, Zhudong, additional, Xia, Ziyuan, additional, Ding, Xuezhi, additional, Hu, Shengbiao, additional, Zhang, Youming, additional, Rang, Jie, additional, and Xia, Liqiu, additional

Published
2021
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17. Comparative Proteomics Reveals the Effect of the Transcriptional Regulator Sp13016 on Butenyl-Spinosyn Biosynthesis in Saccharopolysp ora pogona .

Author

Tang J, He H, Li Y, Liu Z, Xia Z, Cao L, Zhu Z, Shuai L, Liu Y, Wan Q, Luo Y, Zhang Y, Rang J, and Xia L

Subjects
Bacterial Proteins genetics, Macrolides, Proteomics, Saccharopolyspora genetics
Abstract

Butenyl-spinosyn is a highly effective and broad-spectrum biopesticide produced by Saccharopolyspora pogona . However, the yield of this compound is difficult to increase because the regulatory mechanism of secondary metabolism is still unknown. Here, the transcriptional regulator Sp13016 was discovered to be highly associated with butenyl-spinosyn synthesis and bacterial growth. Overexpression of sp13016 improved butenyl-spinosyn production to a level that was 2.84-fold that of the original strain, while deletion of sp13016 resulted in a significant decrease in yield and growth inhibition. Comparative proteomics revealed that these phenotypic changes were attributed to the influence of Sp13016 on the central carbon metabolism pathway to regulate the supply of precursors. Our research helps to reveal the regulatory mechanism of butenyl-spinosyn biosynthesis and provides a reference for increasing the yield of natural products of Actinomycetes .

Published
2021
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