17 results on '"Ken Fujiwara"'
Search Results
2. Association of intensity and dominance of CEOs’ smiles with corporate performance
- Author
-
Ken Fujiwara and Pierrich Plusquellec
- Subjects
Medicine ,Science - Abstract
Abstract This study investigated whether the facial expressions of chief executive officers (CEOs) are associated with corporate performance. A photograph of the CEO or president of each company that appeared on the Fortune Global 500 list for 2018 was taken from the company’s official website. The smile intensity and action unit activation in each face were calculated using a pre-trained machine learning algorithm, FACET. The results revealed a positive association between smile intensity and company profit, even when controlling for the company’s geographic location (Western culture versus others) and the CEO’s gender. Furthermore, when the type of smile was examined with the activation of each action unit, this significant positive association was identified in the dominant smile but not in the reward and affiliative smiles. Relationships among the leader’s smile intensity, group strategy, and group performance are discussed.
- Published
- 2024
- Full Text
- View/download PDF
3. Different effects of visual occlusion on interpersonal coordination of head and body movements during dyadic conversations
- Author
-
Kentaro Kodama, Daichi Shimizu, and Ken Fujiwara
- Subjects
interpersonal coordination ,synchrony ,perceptual coupling ,visual information ,compensatory behavior ,cross-recurrence quantification analysis ,Psychology ,BF1-990 - Abstract
IntroductionIn recent decades, interpersonal coordination and synchrony have been extensively examined in the field of psychology and cognitive science. Studies suggest that perceptual information enables interpersonal coordination and that perceptual noise may even enhance coordination. However, how these perceptual factors influence interpersonal coordination dynamics between head and body movements remains unclear. This study investigated the effect of visual information on the interpersonal coordination of head and body movements during dyadic conversations.MethodsThe availability of visual information was manipulated by positioning a partition halfway between a pair of participants, and the conversations were recorded using a video camera. A video-based human pose estimation software (OpenPose) was used to quantify each interlocutor’s head and body movements, which were submitted for cross-recurrence quantification analysis (CRQA), to assess the degree of coordination between the interlocutors.ResultsThe results showed different effects between head- and body-movement coordination (i.e., a CRQA measure, maximum line length). The occlusion of visual information increased head-movement coordination, whereas it decreased body-movement coordination.DiscussionThe results suggest that a distinct mechanism may be present at the head- and body-movement coordination level and this study observed differing appearances of compensatory behaviors. Further studies should be conducted to investigate the complex relationships between interpersonal coordination dynamics and various kinds of communication constraints, such as long-term or short-term, and lower-order (perceptual-motor) or higher-order (cognitive-social) level constraints.
- Published
- 2024
- Full Text
- View/download PDF
4. The association between synchrony and intellectual productivity in a group discussion : a study using the SenseChair
- Author
-
Motoki Manabe, Ken Fujiwara, Kodai Ito, and Yuichi Itoh
- Subjects
History of scholarship and learning. The humanities ,AZ20-999 ,Social Sciences - Abstract
Abstract In recent years, multi-person meeting formats such as brainstorming sessions and hackathons have become prevalent in numerous workplaces. Despite the introduction of several effective methods and guidelines for these meeting formats, optimal performance is not always attained, even when utilizing such methods and guidelines. There has been active research to support intellectual production activities, and there is a demand to establish a quantitative index to assess the intellectual productivity of a group. In this study, we employed a method for evaluating the intellectual productivity of a group by analyzing the physical movements of conversationalists during discussions. With our main focus on the synchrony of conversationalists, we examined the correlation between synchrony and intellectual productivity and delved further into our analysis, specifically exploring the relationship between pairwise synchrony and various factors such as the number of ideas generated, the number of idea categories, and the originality of ideas produced during a discussion. Our analysis revealed a marginally significant positive correlation between the mean value of pairwise synchrony and the number of ideas generated by the team during the discussion. Our findings indicate that, as more pairs synchronize their body movements during a discussion, a greater number of ideas are generated by the team. Additionally, we suggest that analyzing local pairwise synchrony, focusing on pairs of participants rather than all participants in the discussion could provide further insights into the correlation with the intellectual productivity of the group as a whole.
- Published
- 2024
- Full Text
- View/download PDF
5. Fluctuation of CD9/SOX2-positive cell populations during the turnover of GH- and TSH-producing cells in the adult anterior pituitary gland
- Author
-
Kotaro HORIGUCHI, Yuto TSUTSUI, Ken FUJIWARA, Takehiro TSUKADA, Takashi NAKAKURA, Saishu YOSHIDA, Rumi HASEGAWA, and Shu TAKIGAMI
- Subjects
cluster of differentiation 9 (cd9) ,growth hormone (gh) ,pituitary ,sex-determining region y-box 2 (sox2) ,thyroid-stimulating hormone (tsh) ,Reproduction ,QH471-489 ,Internal medicine ,RC31-1245 - Abstract
The adenohypophysis is comprised of the anterior and intermediate lobes (AL and IL, respectively). Cluster of differentiation 9 (CD9)- and sex-determining region Y-box 2 (SOX2)-positive cells are stem/progenitor hormone-producing cells in the AL. They are located in the marginal cell layer (MCL) facing Rathke’s cleft between the AL and IL (primary niche) and the parenchyma of the AL (secondary niche). We previously showed that, in rats, CD9/SOX2-positive cells in the IL side of the MCL (IL-side MCL) migrate to the AL side (AL-side MCL) and differentiate into prolactin-producing cells (PRL cells) in the AL parenchyma during pregnancy, lactation, and diethylstilbestrol treatment, all of which increase PRL cell turnover. This study examined the changes in CD9/SOX2-positive stem/progenitor cell niches and their proportions by manipulating the turnover of growth hormone (GH)- and thyroid-stimulating hormone (TSH)-producing cells (GH and TSH cells, respectively), which are Pit1 lineage cells, as well as PRL cells. After induction, the isolated CD9/SOX2-positive cells from the IL-side MCL formed spheres and differentiated into GH and TSH cells. We also observed an increased GH cell proportion upon treatment with GH-releasing hormone and recovery from continuous stress and an increased TSH cell proportion upon propylthiouracil treatment, concomitant with alterations in the proportion of CD9/SOX2-positive cells in the primary and secondary niches. These findings suggest that CD9/SOX2-positive cells have the potential to supply GH and TSH when an increase in GH and TSH cell populations is required in the adult pituitary gland.
- Published
- 2023
- Full Text
- View/download PDF
6. Differentiation of stem progenitor CD9/SOX2-positive cells is promoted with increased prolactin-producing and endothelial cells in the pituitary
- Author
-
Kotaro HORIGUCHI, Ken FUJIWARA, Takehiro TSUKADA, Takashi NAKAKURA, Saishu YOSHIDA, Rumi HASEGAWA, and Shu TAKIGAMI
- Subjects
cd9 ,lactotrophs ,pituitary gland ,pregnancy ,stem cells ,Reproduction ,QH471-489 ,Internal medicine ,RC31-1245 - Abstract
Sex-determining region Y-box 2 (SOX2)-positive cells are stem/progenitor cells in the adenohypophysis, comprising the anterior and intermediate lobes (AL and IL, respectively). The cells are located in the marginal cell layer (MCL) facing Rathke’s cleft (primary niche) and the parenchyma of the AL (secondary niche). We previously demonstrated in vitro that the tetraspanin superfamily CD9 and SOX2 double-positive (CD9/SOX2-positive) cells in the IL-side MCL migrate to the AL side and differentiate into hormone-producing and endothelial cells in the AL parenchyma. Here, we performed in vivo studies to evaluate the role of IL-side CD9/SOX2-positive cells in pregnancy, lactation, and treatment with diethylstilbestrol (DES; an estrogen analog) when an increased population of prolactin (PRL) cells was observed in the AL of the rat pituitary. The proportions of CD9/SOX2-, CD9/Ki67-, and PRL/TUNEL-positive cells decreased in the primary and secondary niches during pregnancy and DES treatment. In contrast, the number of CD9/PRL-positive cells increased in the AL-side MCL and AL parenchyma during pregnancy and during DES treatment. The proportion of PRL/Ki67-positive cells increased in the AL-side MCL and AL parenchyma in response to DES treatment. Next, we isolated CD9-positive cells from the IL-side MCL using an anti-CD9 antibody. During cell culture, the cells formed free-floating three-dimensional clusters (pituispheres). Furthermore, CD9-positive cells in the pituisphere differentiated into PRL cells, and their differentiation potential was promoted by DES. These findings suggest that CD9/SOX2-positive cells in the IL-side MCL may act as adult stem cells in the AL parenchyma that supply PRL cells under the influence of estrogen.
- Published
- 2022
- Full Text
- View/download PDF
7. Antiphase synchrony increases perceived entitativity and uniqueness: A joint hand-clapping task
- Author
-
Ken Fujiwara, Kunihiko Nomura, and Miki Eto
- Subjects
synchrony ,relative phase ,antiphase ,in-phase ,entitativity ,uniqueness ,Psychology ,BF1-990 - Abstract
In- and antiphase are the dominant patterns identified in the study of synchrony in relative phases. Many previous studies have focused on in-phase synchrony and compared it to asynchrony, but antiphase synchrony has yet not been the subject of much research attention. The limited findings on antiphase synchrony suggest that its role or nature is unclear or unstable in human interaction. To account for this factor, this study examined the possibility that antiphase synchrony simultaneously induced perceived entitativity and uniqueness. The results of an experiment employing a joint hand-clapping task supported this prediction. Further, the elevated feeling of uniqueness in those who experienced antiphase synchrony may have increased the self-other overlap for those who felt oneness with their partner, but it decreased overlap for those who did not. The theoretical implications for synchrony literature are discussed.
- Published
- 2023
- Full Text
- View/download PDF
8. Truth-tellers' and liars' synchrony during attitude-inconsistent conversations
- Author
-
Norah E. Dunbar, Ken Fujiwara, and Quinten S. Bernhold
- Subjects
strategic synchrony hypothesis ,communication accommodation theory ,interpersonal deception theory ,interactional synchrony ,cross-wavelet transform ,motion energy analysis ,Communication. Mass media ,P87-96 - Abstract
The recently-proposed strategic synchrony hypothesis holds that deceivers (more than truth-tellers) use nonverbal synchrony as a way to maintain their credibility and the smooth flow of interactions. However, important questions remain as to how an interaction partner's behavior and the topic of interaction qualify the strategic synchrony hypothesis. This study considered whether naïve participants (i.e., truth-tellers and deceivers) synchronize differently to high- and low-involvement partners (i.e., confederates) depending on whether the partners discuss climate change or tuition increases, two salient conversational topics for our participants. Deceivers who discussed climate change with a high-involvement partner were especially likely to subjectively perceive that both they themselves and their partner initiated synchrony during the discussion of climate change. However, objective automated analyses of bodily movement synchrony revealed a different set of findings: Dyads with a truth-teller demonstrated higher increases in synchrony than dyads with a deceiver when moving from a superficial discussion of what they liked about their university to a direct discussion of climate change. Results are discussed in terms of how they advance the strategic synchrony hypothesis.
- Published
- 2023
- Full Text
- View/download PDF
9. Expression and localization of tight junction-related proteins in adult rat pituitary stem/progenitor cell niches
- Author
-
Saishu YOSHIDA, Hideaki YURINO, Masaaki KOBAYASHI, Naoto NISHIMURA, Kentaro YANO, Ken FUJIWARA, Shin-ichi HASHIMOTO, Takako KATO, and Yukio KATO
- Subjects
rat pituitary ,stem cell niche ,stem/progenitor cells ,tight junction ,Reproduction ,QH471-489 ,Internal medicine ,RC31-1245 - Abstract
Pituitary endocrine cells are supplied by Sox2-expressing stem/progenitor cells in the anterior lobe of the adult pituitary gland. These SOX2-positive cells are maintained in two types of microenvironments (niches): the marginal cell layer (MCL)-niche and the parenchymal-niche. Recently, we isolated dense SOX2-positive cell clusters from the parenchymal-niche by taking advantage of their resistance to protease treatment as parenchymal stem/progenitor cell (PS)-clusters. In the present study, by analyzing these isolated PS-clusters, we attempted to identify novel structural characteristics of pituitary stem/progenitor cell niches. Quantitative real-time PCR showed that tight junction-related genes were distinctly expressed in the isolated PS-clusters. Immunocytostaining showed that the tight junction molecules, ZO-1 and occludin, were localized in the apical membrane facing the pseudo-follicle-like structure of the isolated PS-clusters regardless of the expression of S100β, which distinguishes the sub-population of SOX2-positive cells. Furthermore, immunohistochemistry of the pituitary glands of adult rats clearly demonstrated that ZO-1 and occludin were densely present in the parenchymal-niche encircling the pseudo-follicle, while they were observed in the apical membrane in the MCL-niche facing the residual lumen. Collectively, these tight junction-related proteins might be involved in the architecture and maintenance of the plasticity of pituitary stem/progenitor cell niches.
- Published
- 2022
- Full Text
- View/download PDF
10. Different AT(N) profiles and clinical progression classified by two different N markers using total tau and neurofilament light chain in cerebrospinal fluid
- Author
-
Takashi Sakurai, Kengo Ito, Koichi Kozaki, Kenji Toba, Hiroshige Fujishiro, Masanori Nakagawa, Kazuo Ogawa, Hiroshi Yamauchi, Chio Okuyama, Hiroshi Ito, Daisuke Watanabe, Satoshi Koyama, Ryosuke Takahashi, Kazunori Terasaki, Harushi Mori, Tetsuya Maeda, Masaru Suzuki, Masatoyo Nishizawa, Mikio Shoji, Mineo Yamazaki, Etsuro Matsubara, Shuichi Ikeda, Hidehiro Mizusawa, Kenji Nakashima, Jun Takeuchi, Hiroyuki Shimada, Takashi Kudo, Nobuyuki Saito, Hiroyuki Arai, Takashi Yamazaki, Mitsutoshi Okazaki, Takeshi Iwatsubo, Nobuo Sanjo, Masaki Takao, Shigeo Murayama, Masahito Yamada, Yuichi Sato, Satoshi Takahashi, Harumasa Takano, Masuhiro Sakata, Shunji Mugikura, Shun Shimohama, Takashi Kato, Toshiki Mizuno, Yukiko Yamada, Daisuke Yamamoto, Makoto Higuchi, Yu Nakamura, Yu Hayasaka, Yoshiko Fukushima, Takayuki Obata, Kimiko Yoshimaru, Shinichi Sakamoto, Kaori Watanabe, Masashi Tsujimoto, Osamu Yokota, Seishi Terada, Atsushi Watanabe, Akinori Miyashita, Ryozo Kuwano, Daisuke Yamaguchi, Tetsuaki Arai, Rieko Okada, Hiroshi Matsuda, Kyoko Ito, Kenji Ishii, Yukio Miki, Yuka Yamamoto, Toru Takahashi, Makoto Sasaki, Ken Nagata, Hajime Sato, Miwako Takahashi, Toshimitsu Momose, Isao Ito, Masakazu Yamagishi, Mayumi Watanabe, Hitoshi Shibuya, Shin-ichi Urayama, Hidenao Fukuyama, Toshio Kawamata, Yasuji Yamamoto, Kiyoshi Maeda, Manabu Ikeda, Mamoru Hashimoto, Takeshi Kawarabayashi, Masaki Ikeda, Eizo Iseki, Kazunari Ishii, Yuko Saito, Miharu Samuraki, Heii Arai, Takashi Asada, Haruo Hanyu, Katsuyoshi Mizukami, Takahiko Tokuda, Yukihiko Washimi, Mitsuhiro Yoshita, Hitoshi Shimada, Fumitoshi Niwa, Hitoshi Shinotoh, Tetsuya Suhara, Masatoshi Takeda, YOKO KONAGAYA, Takaaki Mori, Kensaku Kasuga, Takayoshi Tokutake, Takeshi Ikeuchi, Hiroaki Kazui, Noriko Sato, Takeshi Tamaru, Masanobu Takahashi, Yasuhiro Nakata, Yasumasa Yoshiyama, Hisatomo Kowa, Shuichi Ono, Takuya Ohkubo, Yasuo Kuwabara, Tomoko Nakazawa, Kazutomi Kanemaru, Toshiaki Taoka, Nobuyuki Okamura, Hiroki Hayashi, Shin Tanaka, Kayoko Kikuchi, Masataka Kikuchi, Tamao Tsukie, Kazushi Suzuki, Ryoko Ihara, Atsushi Iwata, Norikazu Hara, Morihiro Sugishita, Michio Senda, Masaki Saitoh, Rika Yamauchi, Takashi Hayashi, Seiju Kobayashi, Norihito Nakano, Junichiro Kanazawa, Takeshi Ando, Chiyoko Takanami, Masato Hareyama, Masamitsu Hatakenaka, Eriko Tsukamoto, Shinji Ochi, Yasuhito Wakasaya, Takashi Nakata, Naoko Nakahata, Yoshihiro Takai, Hisashi Yonezawa, Junko Takahashi, Masako Kudoh, Yutaka Matsumura, Yohsuke Hirata, Tsuyoshi Metoki, Susumu Hayakawa, Masayuki Takeda, Toshiaki Sasaki, Koichiro Sera, Yoshihiro Saitoh, Shoko Goto, Kuniko Ueno, Hiromi Sakashita, Kuniko Watanabe, Yasushi Kondoh, Daiki Takano, Mio Miyata, Hiromi Komatsu, Tomomi Sinoda, Rena Muraoka, Hitomi Ito, Aki Sato, Toshibumi Kinoshita, Hideyo Toyoshima, Kaoru Sato, Shigeki Sugawara, Fumiko Kumagai, Katsutoshi Furukawa, Masaaki Waragai, Naoki Tomita, Mari Ootsuki, Katsumi Sugawara, Satomi Sugawara, Atsushi Umetsu, Takanori Murata, Tatsuo Nagasaka, Yukitsuka Kudo, Manabu Tashiro, Shoichi Watanuki, Saeri Ishikawa, Emiko Kishida, Nozomi Sato, Mieko Hagiwara, Kumi Yamanaka, Takeyuki Watanabe, Taeko Takasugi, Shoichi Inagawa, Kenichi Naito, Masanori Awaji, Tsutomu Kanazawa, Kouiti Okamoto, Tsuneo Yamazaki, Yuiti Tasiro, Syunn Nagamine, Shiori Katsuyama, Sathiko Kurose, Sayuri Fukushima, Etsuko Koya, Makoto Amanuma, Noboru Oriuti, Kouiti Ujita, Kazuhiro Kishi, Kazuhisa Tuda, Etsuko Nakajima, Katsumi Miyamoto, Kousaku Saotome, Tomoya Kobayashi, Saori Itoya, Jun Ookubo, Toshiya Akatsu, Yoshiko Anzai, Junya Ikegaki, Yuuichi Katou, Kaori Kimura, Ryou Kuchii, Hajime Saitou, Kazuya Shinoda, Satoka Someya, Hiroko Taguchi, Kazuya Tashiro, Masaya Tanaka, Tatsuya Nemoto, Ryou Wakabayashi, Hitoshi Shinoto, Kazuko Suzuki, Izumi Izumida, Katsuyuki Tanimoto, Takahiro Shiraishi, Junko Shiba, Hiroaki Yano, Miki Satake, Aimi Nakui, Yae Ebihara, Tomomi Hasegawa, Mami Kato, Yuki Ogata, Hiroyuki Fujikawa, Nobuo Araki, Yoshihiko Nakazato, Takahiro Sasaki, Tomokazu Shimadu, Etsuko Imabayashi, Asako Yasuda, Etuko Yamamoto, Natsumi Nakamata, Noriko Miyauchi, Keiko Ozawa, Rieko Hashimoto, Taishi Unezawa, Takafumi Ichikawa, Tunemichi Mihara, Masaya Hirano, Shinichi Watanabe, Junichiro Fukuhara, Hajime Matsudo, Toshihiro Hayashi, Toji Miyagawa, Mizuho Yoshida, Yuri Koide, Eriko Samura, Kurumi Fujii, Nagae Orihara, Akira Kunimatsu, Takuya Arai, Yoshiki Kojima, Masami Goto, Takeo Sarashina, Syuichi Uzuki, Seiji Katou, Yoshiharu Sekine, Yukihiro Takauchi, Chiine Kagami, Yasushi Nishina, Maria Sakaibara, Yumiko Okazaki, Maki Obata, Yuko Iwata, Mizuho Minami, Yasuko Hanabusa, Hanae Shingyouji, Kyoko Tottori, Aya Tokumaru, Makoto Ichinose, Kazuya Kume, Syunsuke Kahashi, Kunimasa Arima, Tadashi Tukamoto, Yuko Nagahusa, Maki Yamada, Tiine Kodama, Tomoko Takeuchi, Keiichiro Ozawa, Yoshiko Kawaji, Kyouko Tottori, Satoshi Sawada, Makoto Mimatsu, Daisuke Nakkamura, Shunichirou Horiuchi, Tsuneyoshi Ota, Aiko Kodaka, Yuko Tagata, Tomoko Nakada, Kiyoshi Sato, Norio Murayama, Satoshi Kimura, Hirofumi Sakurai, Takahiko Umahara, Hidekazu Kanetaka, Kaori Arashino, Mikako Murakami, Ai Kito, Seiko Miyagi, Kaori Doi, Kazuyoshi Sasaki, Akiko Ishiwata, Yasushi Arai, Akane Nogami, Sumiko Fukuda, Sayaka Kimura, Ayako Machida, Kuninori Kobayashi, Mutsufusa Watanabe, Hiromi Utashiro, Yukiko Matsumoto, Kumiko Hagiya, Yoshiko Miyama, Takako Shinozaki, Haruko Hiraki, Isamu Ohashi, Akira Toriihara, Shinichi Ohtani, Toshifumi Matsui, Tomomi Toyama, Hideki Sakurai, Kumiko Sugiura, Hirofumi Taguchi, Shizuo Hatashita, Akari Imuta, Akiko Matsudo, Daichi Wakebe, Hideki Hayakawa, Mitsuhiro Ono, Takayoshi Ohara, Yutaka Arahata, Akinori Takeda, Akiko Yamaoka, Hideyuki Hattori, Miura Hisayuki, Hidetoshi Endou, Syousuke Satake, Young Jae Hong, Katsunari Iwai, Kenji Yoshiyama, Masaki Suenaga, Sumiko Morita, Teruhiko Kachi, Rina Miura, Takiko Kawai, Ai Honda, Kengo Itou, Ken Fujiwara, Rikio Katou, Mariko Koyama, Naohiko Fukaya, Akira Tsuji, Hitomi Shimizu, Hiroyuki Fujisawa, Takanori Sakata, Kenjiro Ono, Moeko Shinohara, Yuki Soshi, Kozue Niwa, Chiaki Doumoto, Mariko Hata, Miyuki Matsushita, Mai Tsukiyama, Nozomi Takeda, Sachiko Yonezawa, Ichiro Matsunari, Osamu Matsui, Fumiaki Ueda, Yasuji Ryu, Masanobu Sakamoto, Yasuomi Ouchi, Madoka Chita, Yumiko Fujita, Rika Majima, Hiromi Tsubota, Umeo Shirasawa, Masashi Sugimori, Wataru Ariya, Yuuzou Hagiwara, Yasuo Tanizaki, Hajime Takechi, Chihiro Namiki, Kengo Uemura, Takeshi Kihara, Shizuko Tanaka-Urayama, Emiko Maeda, Natsu Saito, Shiho Satomi, Konomi Kabata, Tomohisa Okada, Koichi Ishizu, Shigeto Kawase, Satoshi Fukumoto, Masaki Kondo, Yoko Oishi, Mariko Yamazaki, Yoku Asano, Chizuru Hamaguchi, Kei Yamada, Kentaro Akazawa, Shigenori Matsushima, Takamasa Matsuo, Toshiaki Nakagawa, Takeshi Nii, Takuji Nishida, Kuniaki Kiuchi, Masami Fukusumi, Hideyuki Watanabe, Akihiro Nogi, Toshihisa Tanaka, Naoyuki Sato, Masayasu Okochi, Takashi Morihara, Shinji Tagami, Noriyuki Hayashi, Masahiko Takaya, Tamiki Wada, Mikiko Yokokoji, Hiromichi Sugiyama, Shuko Takeda, Keiko Nomura, Mutsumi Tomioka, Eiichi Uchida, Yoshiyuki Ikeda, Mineto Murakami, Takami Miki, Suzuka Ataka, Motokatsu Kanemoto, Akitoshi Takeda, Rie Azuma, Yuki Iwamoto, Naomi Tagawa, Junko Masao, Yuka Matsumoto, Yuko Kikukawa, Hisako Fujii, Junko Matsumura, Susumu Shiomi, Joji Kawabe, Yoshihiro Shimonishi, Mitsuji Higashida, Tomohiro Sahara, Takashi Yamanaga, Hiroyuki Tsushima, Kazuo Sakai, Haruhiko Oda, Taichi Akisaki, Mizuho Adachi, Masako Kuranaga, Sachi Takegawa, Yoshihiko Tahara, Takeshi Ishihara, Hajime Honda, Yuki Kishimoto, Naoya Takeda, Nao Imai, Mayumi Yabe, Kentaro Ida, Daigo Anami, Seiji Inoue, Toshi Matsushita, Reiko Wada, Shinsuke Hiramatsu, Hiromi Tonbara, Reiko Yamamoto, Kenji Wada-Isoe, Saori Yamasaki, Eijiro Yamashita, Ichiro Ishikawa, Sonoko Danjo, Tomomi Shinohara, Miyuki Ueno, Yuka Kashimoto, Yoshihiro Nishiyama, Narihide Kimura, Yasuhiro Sasakawa, Takashi Ishimori, Yukito Maeda, Tatsuo Yamada, Shinji Ouma, Aika Fukuhara-Kaneumi, Nami Sakamoto, Rie Nagao, Kengo Yoshimitsu, Ryuji Nakamuta, Minoru Tanaka, Keiichirou Kaneda, Yuusuke Yatabe, Kazuki Honda, Naoko Ichimi, Fumi Akatuka, Mariko Morinaga, Miyako Noda, Mika Kitajima, Toshinori Hirai, Shinya Shiraishi, Naoji Amano, Shinsuke Washizuka, Shin Inuzuka, Tetsuya Hagiwara, Nobuhiro Sugiyama, Yatsuka Okada, Tomomi Ogihara, Takehiko Yasaki, Minori Kitayama, Tomonori Owa, Akiko Ryokawa, Rie Takeuchi, Satoe Goto, Keiko Yamauchi, Mie Ito, Tomoki Kaneko, Hitoshi Ueda, Ban Mihara, Hirofumi Kubo, Akiko Takano, Gou Yasui, Masami Akuzawa, Kaori Yamaguchi, Toshinari Odawara, Megumi Shimamura, Mikiko Sugiyama, Naomi Oota, Shigeo Takebayashi, Yoshigazu Hayakawa, Mitsuhiro Idegawa, and Noriko Toya
- Subjects
Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 - Abstract
Background The AT(N) classification was proposed for categorising individuals according to biomarkers. However, AT(N) profiles may vary depending on the markers chosen and the target population.Methods We stratified 177 individuals who participated in the Japanese Alzheimer’s Disease Neuroimaging Initiative by AT(N) classification according to cerebrospinal fluid (CSF) biomarkers. We compared the frequency of AT(N) profiles between the classification using total tau and neurofilament light chain (NfL) as N markers (AT(N)tau and AT(N)NfL). Baseline characteristics, and longitudinal biological and clinical changes were examined between AT(N) profiles.Results We found that 9% of cognitively unimpaired subjects, 49% of subjects with mild cognitive impairment, and 61% of patients with Alzheimer’s disease (AD) dementia had the biological AD profile (ie, A+T+) in the cohort. The frequency of AT(N) profiles substantially differed between the AT(N)tau and AT(N)NfL classifications. When we used t-tau as the N marker (AT(N)tau), those who had T− were more frequently assigned to (N)−, whereas those who had T+were more frequently assigned to (N)+ than when we used NfL as the N marker (AT(N)NfL). During a follow-up, the AD continuum group progressed clinically and biologically compared with the normal biomarker group in both the AT(N)tau and AT(N)NfL classifications. More frequent conversion to dementia was observed in the non-AD pathological change group in the AT(N)tau classification, but not in the AT(N)NfL classification.Conclusions AT(N)tau and AT(N)NfL in CSF may capture different aspects of neurodegeneration and provide a different prognostic value. The AT(N) classification aids in understanding the AD continuum biology in various populations.
- Published
- 2022
- Full Text
- View/download PDF
11. Detection of nodding of interlocutors using a chair-shaped device and investigating relationship between a divergent thinking task and amount of nodding.
- Author
-
Kento Nishimura, Kodai Ito, Ken Fujiwara, Kazuyuki Fujita, and Yuichi Itoh
- Published
- 2023
- Full Text
- View/download PDF
12. Influence of Visual Information on Interpersonal Coordination of Head- and Body- Movement During Dyad Conversations.
- Author
-
Kentaro Kodama, Daichi Shimizu, and Ken Fujiwara
- Published
- 2022
13. Synchrony facilitates altruistic decision making for non-human avatars.
- Author
-
Ken Fujiwara, Rens Hoegen, Jonathan Gratch, and Norah E. Dunbar
- Published
- 2022
- Full Text
- View/download PDF
14. The multiciliated cells in Rathke’s cleft express CYP26A1 and respond to retinoic acid in the pituitary
- Author
-
Kotaro Horiguchi, Ken Fujiwara, Takehiro Tsukada, Takashi Nakakura, Saishu Yoshida, Rumi Hasegawa, and Shu Takigami
- Subjects
Male ,Histology ,Pituitary Gland, Anterior ,Pituitary Gland ,Animals ,Tretinoin ,Cell Biology ,Rats, Wistar ,Retinoic Acid 4-Hydroxylase ,Rats ,Pathology and Forensic Medicine - Abstract
The adenohypophysis consists of the anterior and intermediate lobes (AL and IL). The marginal cell layer (MCL), including the ventral region of the IL and the dorsal region of the AL lining the Rathke's cleft, acts as the primary stem/progenitor cell niches in adult adenohypophysis. The cells of the MCL on the IL side consisted of cluster of differentiation 9 (CD9)-positive stem/progenitor cells with or without motile cilia. However, any additional cellular properties of multiciliated CD9-positive cells are not known. The present study aimed to identify the character of the multiciliated cells in stem cell niche of the pituitary gland. We observed the fine structure of the multiciliated cells in the MCL of male Wistar rats at an early stage after birth and in adulthood (P60) using scanning electron microscopy. Since the previous study showed that the MCL cells of adult rats synthesize retinoic acid (RA), the present study determined whether the multiciliated cells are involved in RA regulation by the expression of retinal aldehyde dehydrogenase 1 (RALDH1) and CYP26A1, an enzyme synthesizing and degrading RA, respectively. Results showed that 96% of multiciliated cells in adult male rats expressed CYP26A1, while 60% expressed RALDH1. Furthermore, the isolated CD9-positive cells from the IL side MCL responded to RA and activated the degradation system of RA by increasing Cyp26a1 expression. These findings indicated that multiciliated cells are involved in RA metabolism in the MCL. Our observations provide novel insights regarding the stem cell niche of the adult pituitary.
- Published
- 2022
15. Nonverbal Synchrony in Technology-Mediated Interviews: A Cross-Cultural Study
- Author
-
Ken Fujiwara, Christopher D. Otmar, Norah E. Dunbar, and Mohemmad Hansia
- Subjects
Social Psychology - Abstract
Technology-mediated communication has changed the way we interact. Since the onset of the COVID-19 pandemic in March 2020, this trend became even more pronounced. Media interviews are no exception. Yet, studies on nonverbal behaviors, especially nonverbal synchrony during such mediated settings, have been scarce. To fill the research gap, this study investigated synchronized patterns between interview hosts' and guests' facial emotional displays and upper body movement during mediated interviews recorded in the countries in Western (mainly the US, with the addition of the UK) and Eastern cultures (Japan). The interviews were categorized into information- or entertainment-driven interviews, depending on the social attributes of the guest. The time series of the valence in facial displays and upper body movement was automatedly measured using FaceReader and Motion Energy Analysis software, respectively, which was analyzed in terms of simultaneous movements, a primary component of synchrony. As predicted, facial synchrony was more prevalent in information-driven interviews, supporting the motivational and strategic account of synchrony. In addition, female-hosted interviews had a higher degree of synchrony, especially in information-driven interviews. Similar patterns were seen in movement synchrony, although not significant. This study is the first evidence of synchrony in technology-mediated interviews in which a host and a guest appear on split-screen to inform or entertain audiences. However, no cultural differences in synchrony were observed. Situational demands in front of the interactants and the goal-driven nature of communication seemed to play a more prominent role than cultural differences in nonverbal synchrony.The online version contains supplementary material available at 10.1007/s10919-022-00416-3.
- Published
- 2022
16. Using Virtual Reality to Improve the Quality of Life of Older Adults with Cognitive Impairments and their Family Members who Live at a Distance
- Author
-
Tamara Afifi, Nancy Collins, Kyle Rand, Chris Otmar, Allison Mazur, Norah E. Dunbar, Ken Fujiwara, Kathryn Harrison, and Rebecca Logsdon
- Subjects
Health (social science) ,Communication - Abstract
This study examines whether using virtual reality (VR) with older adults with mild cognitive impairment (MCI) or mild to moderate dementia with a family member who lives at a distance can improve the quality of life of the older adult and the family member. Twenty-one older adults in a senior living community and a family member (who participated in the VR with the older adult from a distance) engaged in a baseline telephone call, followed by three weekly VR sessions. The VR was associated with improvements in older adults' affect and stress, relationship with their family member, and overall quality of life, compared to baseline. Family members' negative affect, depressive symptoms, and caregiver burden also decreased and their mental health improved after using the VR, compared to baseline. Using the VR, however, did not change their relationship with the older adult. In addition, older adults and family members who experienced the VR sessions as more socially engaging reported better psychological and relational well-being, with older adults also experiencing greater improvements in overall quality of life. Finally, preliminary results suggest that older adults with dementia and their family members might benefit even more from using the VR than older adults with MCI and their family members.
- Published
- 2022
17. Synchrony facilitates altruistic decision making for non-human avatars
- Author
-
Norah E. Dunbar, Ken Fujiwara, Rens Hoegen, and Jonathan Gratch
- Subjects
Avatars ,media_common.quotation_subject ,Interpersonal synchrony ,Agents ,Cross-wavelet analysis ,Affect (psychology) ,Variety (cybernetics) ,Education ,Human-Computer Interaction ,Negotiation ,Arts and Humanities (miscellaneous) ,Prosocial behavior ,Human interaction ,Clinical Research ,Perception ,Non-human ,Psychology ,Cognitive Sciences ,Human-computer communiation ,Social psychology ,General Psychology ,media_common ,Information Systems - Abstract
Synchrony is a natural part of human interaction and is often associated with a variety of prosocial outcomes including affinity and rapport. The purpose of this research was to examine whether human negotiators would synchronize their movements when working with non-human avatars and if so, whether that would affect their perceptions of their negotiations. Results suggest that participants synchronized their movements with the movements of non-human negotiation partners, that greater synchrony was observed when participants engaged in an integrative negotiation compared to a distributive negotiation, and participants that engaged in synchrony reported greater affiliation with their non-human partner. Synchrony also lead to giving more to the non-human agent in an integrative negotiation whereas it had no significant impact on the outcomes in a distributive negotiation. Implications for human-machine interaction are discussed.
- Published
- 2021
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.