9 results on '"Kemal Nas"'
Search Results
2. Clinical Features and Outcomes of Coronavirus Disease 2019 in Patients with Inflammatory Bowel Disease and Spondyloarthropathies
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Mukaddes Tozlu, Gamze Dilek, Mehtap Kalçık Unan, Ayhan Kamanlı, İbrahim Tekeoğlu, Mustafa İhsan Uslan, and Kemal Nas
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Diseases of the digestive system. Gastroenterology ,RC799-869 - Published
- 2022
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3. Investigation of the dual-task performance and affecting factors in female patients with fibromyalgia syndrome
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Beyza Beyrek, İlknur Naz, Yusuf Emuk, Melissa Köprülüoğlu, Elvan Felekoğlu, Emre Uzun, and Kemal Nas
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General Medicine - Published
- 2023
4. Association of pain and clinical factors on disability and quality of life in systemic sclerosis: A cross-sectional study from Turkish League Against Rheumatism Network
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Remzi Çevik, Serda Em, Kemal Nas, Murat Toprak, Gizem Cengiz, Mustafa Çalış, İlhan Sezer, Ayşe Ünal Enginar, Pınar Bora Karslı, Sinem Sağ, Betül Sargın, Meltem Alkan Melikoğlu, Yıldıray Aydın, Mehmet Tuncay Duruöz, Halise Hande Gezer, Hilal Ecesoy, Dicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Fizik Tedavi ve Rehabilitasyon Ana Bilim Dalı, Çevik, Remzi, Em, Serda, and Çevik R., Em S., Nas K., Toprak M., Cengiz G., Çalış M., Sezer İ., Enginar A. Ü., Karslı P. B., Sağ S., et al.
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Internal Diseases ,Quality of life ,Internal Medicine Sciences ,Disability ,Klinik Tıp ,systemic sclerosis ,Pain ,Dahili Tıp Bilimleri ,CLINICAL MEDICINE ,Sağlık Bilimleri ,İmmünoloji ve Romatoloji ,İç Hastalıkları ,Clinical Medicine (MED) ,Tıp ,Immunology and Rheumatology ,quality of life ,Rheumatology ,Health Sciences ,Medicine ,Systemic sclerosis ,Klinik Tıp (MED) ,pain ,Romatoloji ,ROMATOLOJİ - Abstract
Objectives: In this study, we aimed to evaluate the factors associated with disability and quality of life (QoL) in Turkish patients with systemic sclerosis (SSc). Patients and methods: Between January 2018 and January 2019, a total of 256 SSc patients (20 males, 236 females; mean age: 50.9±12.4 years; range, 19 to 87 years) who were diagnosed with SSc were included in the study. Disability and health-related QoL (HRQoL) were evaluated by the Health Assessment Questionnaire (HAQ), scleroderma HAQ (SHAQ), Duruöz Hand Index (DHI), and Short Form-36 (SF-36). Linear regression analysis methods were used to describe factors associated with disability and QoL of the patients. Results: All disability scores were higher and HRQoL scores were lower in diffuse cutaneous SSc patients compared limited cutaneous SSc, and differentiations were significant (p=0.001 and p=0.007). In multiple regression, pain (VAS) was the strongest predictor for high disability and low QoL scores (p Conclusion: Clinicians should consider the management of the pain and its sources as a key to improve better functional state and quality of daily life in SSc.
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- 2022
5. Correlation of clinical signs and magnetic resonance imaging findings in patients with lumbar spondylosis
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Lale Altan, Burcu Metin Ökmen, Tiraje Tuncer, Dilşad Sindel, Hasan Fatih Çay, Simin Hepgüler, Selda Sarıkaya, Figen Ayhan, Ajda Bal, Meral Bilgilisoy, Erhan Çapkın, Lale Cerrahoğlu, Remzi Çevik, Deniz Dülgeroğlu, Berrin Durmaz, Tuncay Duruöz, Gülcan Gürer, Savaş Gürsoy, Sami Hizmetli, Cahit Kaçar, Ece Kaptanoğlu, Hilal Ecesoy, Meltem Melikoğlu, Kemal Nas, Hakan Nur, Şüheda Özçakır, Nilay Şahin, Özlem Şahin, Merih Sarıdoğan, Ömer Faruk Şendur, İlhan Sezer, Gülnur Taşçı Bozbaş, Canan Tıkız, and Hatice Uğurlu
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Rheumatology - Abstract
Objectives: The purpose of the study was to contribute further to this debated topic by investigating the correlation of magnetic resonance imaging (MRI) findings with the clinical picture in lumbar spondylosis patients. Patients and methods: This multicenter retrospective study (as part of the epidemiological project of the TLAR-OASG [Turkish League Against Rheumatism-Osteoarthritis Study Group]) included 514 patients (101 males, 413 females; mean age: 63.6±10.8 years; range, 40 to 85 years) who were diagnosed as lumbar spondylosis by clinical examination and direct X-ray between December 2016 and June 2018. Demographic characteristics of patients, Visual Analog Scale for pain, presence of radiating pain, Roland-Morris disability questionnaire, straight leg raise test, deep tendon reflexes, neurogenic intermittent claudication symptoms, any decrease of muscle strength, and abnormality of sensation were recorded. Lumbar MRI findings of the patients were recorded as positive or negative in terms of disc herniation, intervertebral disc degeneration, root compression, osteophytes, spinal stenosis. Statistical analysis was done to assess the correlation between the clinical symptoms, physical examination, and MRI findings. Results: Correlation analysis of the MRI results and the clinical findings showed a significant correlation between straight leg raise test and root compression (p Conclusion: The results of this study corroborate the notion that diligent patient history and physical examination are more valuable than MRI findings, even though a higher incidence of abnormal MRI findings have been obtained in patients with disability and dermatomal radiating pain.
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- 2023
6. The impact of nail psoriasis on disease activity, quality of life, and clinical variables in patients with psoriatic arthritis: A cross-sectional multicenter study
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Gizem Cengiz, Kemal Nas, Yaşar Keskin, Erkan Kılıç, Betül Sargin, Sevtap Acer Kasman, Hakan Alkan, Nilay Sahin, Nihan Cüzdan Balta, İlknur Albayrak Gezer, Dilek Keskin, Cevriye Mülkoğlu, Hatice Reşorlu, Şebnem Ataman, Ajda Bal, Merve Baykul, Mehmet Tuncay Duruöz, Okan Küçükakkaş, Ozan Volkan Yurdakul, Meltem Alkan Melikoğlu, Fikriye Figen Ayhan, Hatice Bodur, Mustafa Çaliş, Erhan Çapkin, Gül Devrimsel, Kevser Gök, Sami Hizmetli, Ayhan Kamanlı, Hilal Ecesoy, Öznur Kutluk, Nesrin Şen, Ömer Faruk Şendur, İbrahim Tekeoğlu, Murat Toprak, Sena Tolu, Tiraje Tuncer, KESKİN, Yaşar, and CENGİZ G., Nas K., KESKİN Y., Kilic E., Sargin B., ACER KASMAN S., ALKAN H., ŞAHİN N., Balta N. C. , Gezer I. A. , et al.
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Internal Diseases ,Severity Index ,Epidemiology ,Distal Interphalangeal Joint ,Pathogenesis ,Recommendations ,Sağlık Bilimleri ,İmmünoloji ve Romatoloji ,Severity of Illness Index ,İç Hastalıkları ,Clinical Medicine (MED) ,Immunology and Rheumatology ,Ankylosing-Spondylitis ,Nail Diseases ,Rheumatology ,Health Sciences ,Onycholysis ,Prevalence ,Humans ,Psoriasis ,Klinik Tıp (MED) ,ROMATOLOJİ ,clinical characteristics ,Features ,psoriatic arthritis ,Internal Medicine Sciences ,Klinik Tıp ,Arthritis, Psoriatic ,Dahili Tıp Bilimleri ,CLINICAL MEDICINE ,nail psoriasis ,Tıp ,Cross-Sectional Studies ,A cross-sectional multicenter study.-, International journal of rheumatic diseases, 2022 [Cengiz G., Nas K., Keskin Y., Kılıç E., Sargin B., Acer Kasman S., Alkan H., Sahin N., Cüzdan Balta N., Gezer İ. A. , et al., -The impact of nail psoriasis on disease activity, quality of life, and clinical variables in patients with psoriatic arthritis] ,Quality of Life ,Medicine ,nail involvement ,Female ,Involvement ,Romatoloji ,disease activity - Abstract
© 2022 Asia Pacific League of Associations for Rheumatology and John Wiley & Sons Australia, Ltd.Aim: Nail involvement is common in psoriatic arthritis. This study assesses clinical characteristics, nail psoriasis prevalence, and impact of nail psoriasis on disease activity in patients with psoriatic arthritis (PsA). Method: This cross-sectional multicenter study was conducted by the Turkish League Against Rheumatism using PsA patients recruited from 25 centers. Demographic and clinical characteristics of PsA patients, such as disease activity measures, quality of life, and nail involvement findings were assessed during routine follow-up examinations. Patients were divided into two groups according to the presence or absence of nail psoriasis and compared using the χ2 test or Fisher exact test for categorical variables and the t-test or Mann-Whitney U test for continuous variables. Results: In 1122 individuals with PsA, 645 (57.5%) displayed nail psoriasis. The most frequent features of fingernails were ridges (38%), followed by pitting (21%) and onycholysis (19%). More females were present in both groups (with and without nail psoriasis; 64% vs 67%, P < 0.282). Patients with nail psoriasis were older, indicated more pain and fatigue, experienced greater swelling, tender joint counts, and skin disease severity, and had a higher disease activity score compared with those without nail psoriasis (all P < 0.05). Conclusion: We demonstrate an increased prevalence of nail psoriasis observed in patients with psoriatic arthritis. Patients with nail involvement experience increased disease activity, lower quality of life, and diminished mental and physical status compared with those without nail involvement.
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- 2023
7. Evaluation of hepatitis serology and frequency of viral reactivation in patients with inflammatory arthritis receiving biologic agents: a multicenter observational study
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Erhan Capkin, Ali Yazıcı, Murat Karkucak, Yunus Durmaz, Murat Toprak, Şebnem Ataman, Nilay Şahin, Nihan Cüzdan, Meliha Kasapoğlu Aksoy, Mustafa Erkut Önder, Münevver Serdaroglu Beyazal, Nilgün Mesci, Merve Baykul, Meltem Alkan Melikoğlu, Hakan Alkan, Deniz Dulgeroglu, Ahmet Kıvanç Cengiz, Kemal Nas, Elif Balevi Batur, Aslı Çalışkan Uçkun, Hülya Deveci, Kemal Erol, İlknur Albayrak Gezer, Gürkan Akgöl, Mehmet Tuncay Duruöz, Okan Küçükakkaş, Selda Sarıkaya, Aylin Rezvani, Tuğba Atan, Feride Göğüş, Gökhan Çağlayan, Yaşar Keskin, Ayşe Selcen Bulut Keskin, Nuran Öz, Gürdal Yılmaz, KESKİN, Yaşar, and Tıp Fakültesi
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Rheumatology ,Immunology ,Viral Reactivation ,Immunology and Allergy ,Inflammatory Arthritis ,a multicenter observational study-, RHEUMATOLOGY INTERNATIONAL, 2022 [ÇAPKIN E., YAZICI A., KARKUCAK M., Durmaz Y., Toprak M., ATAMAN Ş., Sahin N., Cuzdan N., Kasapoglu Aksoy M., Onder M. E. , et al., -Evaluation of hepatitis serology and frequency of viral reactivation in patients with inflammatory arthritis receiving biologic agents] ,Biologic Agents ,Hepatitis - Abstract
To evaluate of hepatitis serology and reactivation frequency in patients with rheumatic disease receiving biologic agents. Our study included patients with inflammatory rheumatic diseases from 23 centers, who were followed up with biological therapy. Demographic and clinical characteristics of the patients, duration of drug use and hepatitis serology and the state of viral reactivation were analyzed. A total of 4060 patients, 2095 being males, were included in our study. Of the patients, 2463 had Ankylosing Spondylitis (AS), 1154 had Rheumatoid Arthritis (RA), 325 had Psoriatic Arthritis (PsA), and 118 had other inflammatory rheumatic diseases. When the viral serology of the patients was evaluated, 79 patients (2%) who were identified as HBs Ag positive, 486 (12%) patients who were HBs Ag negative and anti-HBc IgG positive and 20 patients (0.5%) who were anti-HCV positive. When evaluated on a disease-by-disease basis, the rate of HBsAg was found to be 2.5% in RA, 2% in AS and 0.9% in PsA. Viral reactivation was detected in 13 patients while receiving biologic agents. HBs Ag was positive in nine patients with reactivation and negative in four patients. Anti-HBc IgG, however, was positive. Six of these patients had AS, four had RA, and three had PsA. The development of hepatitis reactivation in 11.4% of HBs Ag positive patients and 0.82% of anti-HBc IgG positive patients due to the use of biologic agents is an important problem for this group of patients. Antiviral prophylaxis is recommended to be started especially in patients who are HBs Ag positive and who are using biologic agents due to viral reactivation. Therefore, it is important to carry out hepatitis screenings before biologic agent treatment and to carefully evaluate the vaccination and prophylaxis requirements. © 2022, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
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- 2022
8. Clinical course and prognostic factors of COVID-19 infection in patients with chronic inflammatory-rheumatic disease: A retrospective, case-control study
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Kemal Nas, Ertuğrul Güçlü, Yaşar Keskin, Gamze Dilek, Mehtap Kalçık Unan, Nurselin Can, İbrahim Tekeoğlu, Ayhan Kamanlı, and KESKİN, YAŞAR
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Rheumatology ,disease course ,COVID-19 ,prognostic factors ,Autoimmune systemic rheumatic diseases - Abstract
Objectives: This study aims to investigate the prognosis of novel coronavirus disease-2019 (COVID-19) infection in patients with the chronic inflammatory-rheumatic disease and evaluate the effects of immunosuppressive drugs on the prognosis, clinical characteristics, laboratory findings and hospitalization periods of the rheumatic patients with COVID-19 infection. Patients and methods: Between April 2020 and March 2021, a total of 101 patients (30 males, 71 females; mean age: 48±14.4 years; range, 46 to 48 years) with the rheumatic diseases diagnosed with COVID-19 infection were included. A total of 102 age- and sex-matched patients (35 males, 67 females; mean age: 44±14.4 years; range, 28 to 44 years) who were diagnosed with COVID-19 infection and had no history of rheumatic disease in the same period were included as the control group. Data including demographic characteristics of the patients, presence of any symptoms of COVID-19 disease, laboratory data at the time of diagnosis, and treatments administered were collected. Results: The rate of hospitalization was higher in 38 (37%) patients without rheumatic diseases than in 31 (31%) patients with rheumatic diseases (p=0.324). The rate of lung infiltration on radiographic examination was higher in patients without rheumatic diseases (40% vs. 49%) (p=0.177). COVID-19 infection symptoms such as anosmia 45 (45%), ageusia 51 (50%), shortness of breath 45(45%), nausea 29 (29%), vomiting 16 (16%), diarrhea 25 (25%) and myalgia-arthralgia 81 (80%) were higher in patients with rheumatic diseases. In terms of laboratory values, lymphocyte count (p=0.031) was statistically higher in patients without rheumatic diseases. Hydroxychloroquine (35%), oseltamivir 10 (10%), antibiotics 27 (26%), acetylsalicylic acid 52 (51%), and supplementary oxygen 25 (25%) treatments which used to cure COVID 19 infection were administered more in patients without rheumatic diseases. The number of treatments administered was higher in patients without rheumatic diseases (p Conclusion: Patients with the chronic inflammatory-rheumatic disease have more symptoms due to COVID-19 infection, but the disease course is not poor and hospitalization rates are lower.
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- 2022
9. Inconsistencies of the Disease Activity Assessment Tools for Psoriatic Arthritis: Challenges to Rheumatologists
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Mustafa Çaliş, Murat Toprak, Halise Hande Gezer, Hatice Bodur, Cevriye Mülkoğlu, Fikriye Figen Ayhan, Nihan Cuzdan, Oznur Kutluk, Ajda Bal, Nilay Sahin, Gizem Cengiz, Tiraje Tuncer, İbrahim Tekeoğlu, Sena Tolu, Ilknur Albayrak Gezer, Betul Sargin, Meltem Alkan Melikoglu, Sami Hizmetli, Nesrin Şen, Sevtap Acer Kasman, Hakan Alkan, Dilek Keskin, Kevser Gok, Yaşar Keskin, Gul Devrimsel, Erhan Capkin, Ayhan Kamanli, Erkan Kilic, Okan Küçükakkaş, Hilal Ecesoy, Mehmet Tuncay Duruöz, Ömer Faruk Şendur, Ozan Volkan Yurdakul, Hatice Reşorlu, İsmihan Sunar, Merve Baykul, Kemal Nas, and KESKİN, Yaşar
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Male ,Disease ,physical examination ,Severity of Illness Index ,middle aged ,Health Assessment Questionnaire ,rheumatologist ,skin and connective tissue diseases ,disease activity score ,Disease Activity in Psoriatic Arthritis ,adult ,Fibromyalgia Rapid Screening Tool ,Remission Induction ,Swollen joints ,anxiety ,Peripheral ,Hospital Anxiety and Depression Scale ,female ,low disease activity ,Treatment Outcome ,Antirheumatic Agents ,depression ,joint swelling ,medicine.symptom ,enthesopathy ,musculoskeletal diseases ,medicine.medical_specialty ,dactylitis ,Remission ,Psoriatic Arthritis ,Challenges to Rheumatologists.-, Joint bone spine, ss.105296, 2021 [Gezer H. H. , Duruöz M. T. , Nas K., Kılıç E., Sargın B., Kasman S. A. , Alkan H., Şahin N., Cengiz G., Cüzdan N., et al., -Inconsistencies of the Disease Activity Assessment Tools for Psoriatic Arthritis] ,prostate specific antigen ,patient-reported outcome ,Article ,rate of remission ,Disease activity ,Psoriatic arthritis ,Rheumatology ,Internal medicine ,medicine ,diverse activity scale ,DAS28 ,Humans ,In patient ,controlled study ,human ,Disease Activity ,clinical assessment tool ,Composite Index ,business.industry ,enthesitis ,Arthritis, Psoriatic ,Enthesitis ,visual analog scale ,clinical assessment ,very low disease activity ,Prostate-Specific Antigen ,medicine.disease ,major clinical study ,antirheumatic agent ,minimal disease activity ,fatigue ,disease duration ,Rheumatologists ,business ,Rheumatism - Abstract
Objective: Currently, concerning the evaluation of psoriatic arthritis (PsA), there is no agreement on a standardized composite index for disease activity that includes all relevant domains. The present study sought to assess the rates of remission (REM)/low disease activity (LDA) and disease states [minimal disease activity (MDA), very low disease activity (VLDA)] as defined by diverse activity scales (DAPSA, DAS28-ESR) in an attempt to display discrepancies across these assessment tools for peripheral PsA. Methods: The study involved 758 patients (496 females, 262 males; mean age 47,1 years) with peripheral PsA who were registered to the Turkish League Against Rheumatism (TLAR) Network. The patients were assessed using the DAS28-ESR, DAPSA, MDA, and VLDA. The overall yield of each scale was assessed in identifying REM and LDA. The presence or absence of swollen joints was separately analysed. Results: The median disease duration was 4 years (range 0-44 years). According to DAPSA and DAS28-ESR, REM was achieved in 6.9% and 19.5% of the patients, respectively. The rates of MDA and VLDA were 16% and 2.9%, respectively. Despite the absence of swollen joints, a significant portion of patients were not considered to be in REM (296 (39.1%) patients with DAS28-ESR, 364 (48%) with DAPSA, and 394 (52%) with VLDA). Conclusion: Patients with peripheral PsA may be assigned to diverse disease activity levels when assessed with the DAS28-ESR, DAPSA, MDA and VLDA, which would inevitably have clinical implications. In patients with PsA a holistic approach seems to be necessary which includes other domains apart from joint involvement, such as skin involvement, enthesitis, spinal involvement, and patient-reported outcomes. © 2021 Société française de rhumatologie
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- 2022
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