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Additional file 1. Fig. S1. Tertiary hospital proportion (%) of all types of hospitals in different provinces and cities. Fig. S2. Correlation of 3-hour bundle and 6-hour bundle compliance with linear regression with 95% CI. Spearman rank correlation test, p = 0.7; p < 0.001. Fig. S3. Correlation between sites of infection, age, sex, and proportion of APACHE II score more than 15. Abbreviations: CNS, central nervous system; older, more than 60 years old. Table S1 Association Between Septic shock case volume quartile and hospital mortality of septic shock.

Additional file 2. The AUCs of predictors for randomly selecting one positive sample and one negative sample from each patient.

Additional file 1. The AUCs of predictors after excluding the cases of electric defibrillation.