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In this paper, a novel series hydraulic hybrid powertrain is proposed for a three-axis all-terrain vehicle. The engine drives two variable displacement pumps responsible for driving and steering, respectively. A variable displacement motor is connected to the ring gear of the planetary coupling mechanism to drive the vehicle and a fixed-displacement motor is connected to the sun gear to steer the vehicle. The active disturbance rejection control with feedforward control is employed to control the engine speed. The engine speed is controlled in a close-looped manner by adjusting the engine throttle. The controller parameters are decided by analyzing the influence of each parameter on the controller performance by means of the control variable method. The simulation results indicate that the proposed control strategy enables the vehicle to obtain better engine speed following and anti-disturbance performance. An all-terrain prototype is established and field tests are carried out to verify the effectiveness of the design and control strategy of the series hydraulic hybrid powertrain for the all-terrain vehicle.

Acute lung injury (ALI) is the most common complication of sepsis. Intravenous injection of HUMSCs can regulate the level of circulating endothelial cytokines and alleviate lung injury in juvenile septic rats. In this study, we performed proteomic and phosphorylated proteomic analysis of lung tissue of juvenile septic rats after Human Umbilical Cord Mesenchymal Stem Cells (HUMSCs) intervention for the first time, and screened the potential proteins and pathways of HUMSCs for therapeutic effect. The 4D proteome quantitative technique was used to quantitatively analyze the lung tissues of septic rats 24 hours (3 biological samples) and 24 hours after HUMSCs intervention (3 biological samples). A total of 213 proteins were identified as differentially expressed proteins, and 971 phosphorylation sites changed significantly. Based on the public database, we analyzed the functional enrichment of these proteins and phosphorylated proteins. In addition, Tenascin-C may be the key differential protein and ECM receptor interaction pathway may be the main signal pathway by using various algorithms to analyze the protein-protein interaction network. Phosphorylation analysis showed that tight junction pathway was closely related to immune inflammatory reaction, and EGFR interacted most, which may be the key differential phosphorylated protein. Finally, 123 conserved motifs of serine phosphorylation site (pS) and 17 conserved motifs of threonine (pT) phosphorylation sites were identified by motif analysis of phosphorylation sites. Results from proteomics and phosphorylated proteomics, the potential new therapeutic targets of HUMSCs in alleviating lung injury in juvenile septic rats were revealed.

Electromagnetic active suspension is an important technique used in vehicles to improve ride comfort and handling stability. To achieve satisfactory suspension performance, the active suspension control requires strong robustness against the vehicle uncertainties and external disturbances. The voice coil motor (VCM) is applied to the active suspension. A suspension model considering the actuator is established. An active suspension controller based on the active disturbance rejection control (ADRC) method is proposed. Through the test platform built, it is demonstrated that the ADRC of VCM active suspension has better performance than the PID. The results indicate that the overshoot and adjustment time of ADRC controller is reduced by 80% and 50%, respectively. The body vertical displacement of the ADRC is 50% smaller than PID.