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3. Covid-19

Author

Jayaratne, Kapila, primary, Dissanayake, Vajira, additional, and Karunapema, Palitha, additional

Published
2022
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4. International virtual confidential reviews of infection-related maternal deaths and near-miss in 11 low- and middle-income countries – case report series and suggested actions

Author

Okafor, Obiageli, Roos, Nathalie, Abdosh, Abdulfetah Abdulkadir, Adesina, Olubukola, Alaoui, Zaynab, Romero, William Arriaga, Assarag, Bouchra, Aworinde, Olufemi, de Bernis, Luc, Castro, Rigoberto, Chrifi, Hassan, Day, Louise Tina, Demissew, Rahel, Aceituno, María Guadalupe Flores, Gadama, Luis, Gashawbeza, Biruck, Keke, Sourou Goufodji, Govule, Philip, Gwako, George, Jayaratne, Kapila, Komboigo, Evelyne Béwendin, Lara, Bredy, Madziyire, Mugove Gerald, Mathai, Matthews, Moulki, Rachid, Moutaouadia, Iatimad, Munjanja, Stephen, Fletes, Carlos Alberto Ochoa, Ortiz, Edgar Ivan, Ouedraogo, Henri Gautier, Qureshi, Zahida, Recidoro, Zenaida Dy, Senanayake, Hemantha, Soma-Pillay, Priya, Tin, Khaing Nwe, Sedami, Pascal, Worku, Dawit, and Bonet, Mercedes

Published
2022
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8. Utilization of Antenatal Care and Pregnancy Outcomes of Women in Advanced Maternal Age at a Tertiary care Hospital in Sri Lanka

Author

Illangasinghe Poojani, Jayaratne Kapila, and Palitha Karunapema

Subjects
Advanced maternal age pregnancy, Adverse pregnancy outcomes of AMA, Contributory factors of AMA, Utilization of antenatal care services
Abstract

Introduction: Childbearing in latter part of reproductive age is challenging. Adverse pregnancy outcomes increase with advanced (>35 years) maternal age (AMA) and comprehensive antenatal care (ANC) usage by AMA women improves their pregnancy outcomes. However, no recent local data are available on the AMA and pregnancy outcomes. Objectives: To describe utilization of ANC and pregnancy outcomes of AMA women delivering at North Colombo Teaching Hospital and assessed the association between utilization of ANC services and selected pregnancy outcomes. Methods: A descriptive cross-sectional study was conducted among 216 women aged >35 years delivered at Colombo North Teaching Hospital selected using a non-probability consecutive sampling method. Women were interviewed within 7 days postpartum inward using an interviewer-administered questionnaire. Selected data were extracted from clinical records. Key elements of ANC (booking visit, type, frequency, services etc.) were scored and their association with pregnancy outcomes were assessed. Results: A total of 216 AMA postpartum women (age range 35–45 years, mean 37.8 (SD=2.4)) were recruited (response rate 100%). Majority (91.7%, n=198) were multiparous. The current pregnancy was planned in 77.8% (n=168) and 52.7% (n=114) experienced antenatal morbidities. Adverse maternal (8.3%, n=18) and newborn (37%, n=80) outcomes were noted. Majority (75.9%, n=164) optimally utilized ANC. Sinhalese (OR=2.98, 95%CI 1.29–6.87, p=0.008), Buddhist (OR=2.53, 95%CI 1.33–4.80, p=0.004) women with intended pregnancies (OR=5.67, 95%CI 2.81–11.43, p Conclusions: Many AMA women are multiparous and with planned pregnancies. Presence of adverse maternal & newborn outcomes is substantial. Majority well utilized ANC and it reduced adverse pregnancy outcomes. Effective strategies should be formulated to promote well-planned pregnancies in early reproductive ages of women.

Published
2023
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9. Additional file 1 of International virtual confidential reviews of infection-related maternal deaths and near-miss in 11 low- and middle-income countries – case report series and suggested actions

Author

Okafor, Obiageli, Roos, Nathalie, Abdosh, Abdulfetah Abdulkadir, Adesina, Olubukola, Alaoui, Zaynab, Romero, William Arriaga, Assarag, Bouchra, Aworinde, Olufemi, de Bernis, Luc, Castro, Rigoberto, Chrifi, Hassan, Day, Louise Tina, Demissew, Rahel, Aceituno, María Guadalupe Flores, Gadama, Luis, Gashawbeza, Biruck, Keke, Sourou Goufodji, Govule, Philip, Gwako, George, Jayaratne, Kapila, Komboigo, Evelyne Béwendin, Lara, Bredy, Madziyire, Mugove Gerald, Mathai, Matthews, Moulki, Rachid, Moutaouadia, Iatimad, Munjanja, Stephen, Fletes, Carlos Alberto Ochoa, Ortiz, Edgar Ivan, Ouedraogo, Henri Gautier, Qureshi, Zahida, Recidoro, Zenaida Dy, Senanayake, Hemantha, Soma-Pillay, Priya, Tin, Khaing Nwe, Sedami, Pascal, Worku, Dawit, and Bonet, Mercedes

Abstract

Additional file 1. Supplementary appendix to “International virtual confidential reviews of infection-related maternal deaths and near-miss in 11 low- and middle-income countries – Case report series and suggested actions. Study forms used for data collection and during the external review meetings. Results of a baseline assessment of maternal death review (MDR) committees and practices in participating GLOSS facilities. Additional information on the causes of deaths and distribution of modifiable factors described in this study.

Published
2022
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10. Perinatal outcomes among births to women with infection during pregnancy.

Author

Baguiya, Adama, Bonet, Mercedes, Guilherme Cecatti, José, Brizuela, Vanessa, Curteanu, Ala, Minkauskiene, Meile, Jayaratne, Kapila, Ribeiro-do-Valle, Carolina Carvalho, Budianu, Mihaela-Alexandra, Paulo Souza, João, Kouanda, Séni, Cecatti, José Guilherme, Souza, João Paulo, WHO Global Maternal Sepsis Study (GLOSS) Research Group, and GLOSS research group

Subjects
PERINATAL death, PREGNANCY, LABOR (Obstetrics), NEONATAL death, EARLY death, COMMUNICABLE disease diagnosis, COMMUNICABLE disease epidemiology, RESEARCH, RESEARCH methodology, GESTATIONAL age, MEDICAL cooperation, EVALUATION research, VAGINA, PREGNANCY outcomes, COMPARATIVE studies, PREGNANCY complications, RESEARCH funding, DEVELOPING countries, INFANT mortality, COMORBIDITY, LONGITUDINAL method
Abstract

Objective: This study is part of the Global Maternal Sepsis Study (GLOSS). It aimed to estimate neonatal near-miss (NNM) and perinatal death frequency and maternal risk factors among births to women with infection during pregnancy in low-income and middle-income countries (LMIC).Design: We conducted a 1-week inception hospital-based cohort study.Setting: The study was carried out in 408 hospitals in 43 LMIC of all the WHO regions in 2017.Patients: We included women with suspected or confirmed infection during pregnancy with at least 28 weeks of gestational age up to day-7 after birth. All babies born to those women were followed from birth until the seventh day after childbirth. Perinatal outcomes were considered at the end of the follow-up.Main Outcome Measures: Perinatal outcomes were (i) babies alive without severe complication, (ii) NNM and (iii) perinatal death (stillbirth and early neonatal death).Results: 1219 births were analysed. Among them, 25.9% (n=316) and 10.1% (n=123) were NNM and perinatal deaths, respectively. After adjustment, maternal pre-existing medical condition (adjusted odds ratios (aOR)=1.5; 95% CI 1.1 to 2.0) and maternal infection suspected or diagnosed during labour (aOR=1.9; 95% CI 1.2 to 3.2) were the independent risk factors of NNM. Maternal pre-existing medical condition (aOR=1.7; 95% CI 1.0 to 2.8), infection-related severe maternal outcome (aOR=3.8; 95% CI 2.0 to 7.1), mother's infection suspected or diagnosed within 24 hours after childbirth (aOR=2.2; 95% CI 1.0 to 4.7) and vaginal birth (aOR=1.8; 95% CI 1.1 to 2.9) were independently associated with increased odds of perinatal death.Conclusions: Overall, one-third of births were adverse perinatal outcomes. Pre-existing maternal medical conditions and severe infection-related maternal outcomes were the main risk factors of adverse perinatal outcomes. [ABSTRACT FROM AUTHOR]

Published
2021
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