9 results on '"Javelle, P."'
Search Results
2. Learning Regionalization using Accurate Spatial Cost Gradients within a Differentiable High-Resolution Hydrological Model: Application to the French Mediterranean Region
- Author
-
Huynh, Ngo Nghi Truyen, Garambois, Pierre-André, Colleoni, François, Renard, Benjamin, Roux, Hélène, Demargne, Julie, Jay-Allemand, Maxime, and Javelle, Pierre
- Subjects
Computer Science - Machine Learning ,Electrical Engineering and Systems Science - Signal Processing - Abstract
Estimating spatially distributed hydrological parameters in ungauged catchments poses a challenging regionalization problem and requires imposing spatial constraints given the sparsity of discharge data. A possible approach is to search for a transfer function that quantitatively relates physical descriptors to conceptual model parameters. This paper introduces a Hybrid Data Assimilation and Parameter Regionalization (HDA-PR) approach incorporating learnable regionalization mappings, based on either multi-linear regressions or artificial neural networks (ANNs), into a differentiable hydrological model. This approach demonstrates how two differentiable codes can be linked and their gradients chained, enabling the exploitation of heterogeneous datasets across extensive spatio-temporal computational domains within a high-dimensional regionalization context, using accurate adjoint-based gradients. The inverse problem is tackled with a multi-gauge calibration cost function accounting for information from multiple observation sites. HDA-PR was tested on high-resolution, hourly and kilometric regional modeling of 126 flash-flood-prone catchments in the French Mediterranean region. The results highlight a strong regionalization performance of HDA-PR especially in the most challenging upstream-to-downstream extrapolation scenario with ANN, achieving median Nash-Sutcliffe efficiency (NSE) scores from 0.6 to 0.71 for spatial, temporal, spatio-temporal validations, and improving NSE by up to 30% on average compared to the baseline model calibrated with lumped parameters. ANN enables to learn a non-linear descriptors-to-parameters mapping which provides better model controllability than a linear mapping for complex calibration cases.
- Published
- 2023
- Full Text
- View/download PDF
3. Signatures-and-sensitivity-based multi-criteria variational calibration for distributed hydrological modeling applied to Mediterranean floods
- Author
-
Huynh, Ngo Nghi Truyen, Garambois, Pierre-André, Colleoni, François, and Javelle, Pierre
- Subjects
Mathematics - Optimization and Control - Abstract
Classical calibration methods in hydrology typically rely on a single cost function computed on long-term streamflow series. Even when hydrological models achieve acceptable scores in NSE and KGE, imbalances can still arise between overall model performance and its ability to simulate flood events, particularly flash floods. In this study, the potential of using multi-scale signatures is explored to enhance multi-criteria calibration methods for spatially distributed flood modeling, which remains considerable challenges. We present a novel signatures and sensitivity-based calibration approach implemented into a variational data assimilation algorithm capable to deal with high dimensional spatially distributed hydrological optimization problems. It is tested on 141 flash flood prone catchments mostly located in the French Mediterranean region. Our approach involves computing several signatures, including flood event signatures, using an automated flood segmentation algorithm. We select suitable signatures for constraining the model based on their global sensitivity with the input parameters through global signature-based sensitivity analysis (GSSA). We then perform two multi-criteria calibration strategies using the selected signatures, including a single-objective optimization approach, which transforms the multi-criteria problem into a single-objective function, and a multi-objective optimization approach, which uses a simple additive weighting method to select an optimal solution from the Pareto set. Our results show significant improvements in both calibration and temporal validation metrics, especially for flood signatures, demonstrating the robustness and delicacy of our signatures-based calibration framework for enhancing flash flood forecasting systems.
- Published
- 2023
- Full Text
- View/download PDF
4. Unraveling the Contribution of Serotonergic Polymorphisms, Prefrontal Alpha Asymmetry, and Individual Alpha Peak Frequency to the Emotion-Related Impulsivity Endophenotype
- Author
-
Javelle, Florian, Löw, Andreas, Bloch, Wilhelm, Hosang, Thomas, Jacobsen, Thomas, Johnson, Sheri L, Schenk, Alexander, and Zimmer, Philipp
- Subjects
Clinical Research ,Behavioral and Social Science ,Genetics ,Neurosciences ,Brain Disorders ,Aetiology ,2.1 Biological and endogenous factors ,Endophenotypes ,Genotype ,Humans ,Impulsive Behavior ,Monoamine Oxidase ,Serotonin Plasma Membrane Transport Proteins ,Cortical activity ,Serotonergic polymorphisms ,emotion-related impulsivity ,5-HTTLPR ,MAO-A ,STin2 ,Emotion-related impulsivity ,Individual alpha peak frequency ,Alpha asymmetry ,Psychology ,Cognitive Sciences ,Neurology & Neurosurgery - Abstract
The unique contribution of the serotonin transporter-linked polymorphic region (5-HTTLPR), intronic region 2 (STin2), and monoamine oxidase A (MAO-A) genes to individual differences in personality traits has been widely explored, and research has shown that certain forms of these polymorphisms relate to impulsivity and impulsivity-related disorders. Humans showing these traits are also described as having an asymmetrical prefrontal cortical activity when compared to others. In this explorative study, we examine the relationship between serotonergic neurotransmission polymorphisms, cortical activity features (prefrontal alpha asymmetry, individual alpha peak frequency [iAPF]), emotion-related and non-emotion-related impulsivity in humans. 5-HTTLPR, MAO-A, and STin2 polymorphisms were assessed in blood taken from 91 participants with high emotion-related impulsivity levels. Sixty-seven participants completed resting electroencephalography and a more comprehensive impulsivity index. In univariate analyses, iAPF correlated with both forms of emotion-related impulsivity. In multiple linear regression models, 5-HTTLPR polymorphism (model 1, adj. R2 = 15.2%) and iAPF were significant interacting predictors of emotion-related impulsivity, explaining a large share of the results' variance (model 2, adj. R2 = 21.2%). Carriers of the low transcriptional activity 5-HTTPLR and MAO-A phenotypes obtained higher emotion-related impulsivity scores than others did. No significant results were detected for non-emotion-related impulsivity or for a form of emotion-related impulsivity involving cognitive/motivational reactivity to emotion. Our findings support an endophenotypic approach to impulsivity, showing that tri-allelic 5-HTTLPR polymorphism, iAPF, and their interaction are relevant predictors of one form of emotion-related impulsivity.
- Published
- 2022
5. Clinical and Epidemiological Changes in French Soldiers After Deployment: Impact of Doxycycline Malaria Prophylaxis on Body Weight
- Author
-
Javelle, Emilie, Mayet, Aurélie, Allodji, Rodrigue S, Marimoutou, Catherine, Lavagna, Chrystel, Desplans, Jérôme, Million, Matthieu, Raoult, Didier, and Texier, Gaëtan
- Published
- 2023
- Full Text
- View/download PDF
6. Agroecological crop protection for sustainable agriculture
- Author
-
Deguine, Jean-Philippe, Aubertot, Jean-Noël, Bellon, Stéphane, Côte, François, Lauri, Pierre-Eric, Lescourret, Françoise, Ratnadass, Alain, Scopel, Eric, Andrieu, Nadine, Bàrberi, Paolo, Becker, Nathalie, Bouyer, Jérémy, Brévault, Thierry, Cerdan, Claire, Cortesero, Anne-Marie, Dangles, Olivier, Delatte, Hélène, Dinh, Phuong Thi Yen, Dreyer, Hans, Duru, Michel, Flor, Rica Joy, Gardarin, Antoine, Husson, Olivier, Jacquot, Maxime, Javelle, Aurélie, Justes, Eric, Lam, Mai Thi Xuan, Launay, Marie, Le, Vang Van, Longis, Sandrine, Martin, José, Munier-Jolain, Nicolas, Nguyen, Nga Thi Thu, Nguyen, Truc Thi Ngoc, Penvern, Servane, Petit, Sandrine, Poisot, Anne-Sophie, Robin, Marie-Hélène, Rolland, Bernard, Rusch, Adrien, Sabourin, Eric, Sanguin, Hervé, Sarthou, Jean-Pierre, Sester, Mathilde, Simon, Sylvaine, Sourisseau, Jean-Michel, Steinberg, Christian, Tchamitchian, Marc, Thoumazeau, Alexis, Tibi, Anaïs, Tivet, Florent, Tixier, Philippe, Trinh, Xuan Thi, Vialatte, Aude, Wyckhuys, Kris, and Lamichhane, Jay Ram
- Abstract
Crop losses from pests threaten global food security and safety. In the last six decades, pest control using chemical pesticides has resulted in important yield gains per unit area, worldwide. However, the long-term sustainability of chemical pest control has been increasingly thrown into doubt due to the negative impact on human health, biodiversity, and the environment. Consequently, there is an urgent need to improve the science of crop protection in order to tackle the five key challenges of 21st century agriculture holistically: (i) maintaining or improving agricultural productivity, (ii) producing healthy food, (iii) reducing the negative impacts of agriculture on ecosystem and human health, (iv) ensuring the economic viability of farms, and (v) adapting agriculture to climate change. Agroecological Crop Protection (ACP) can be a powerful approach to address these challenges, as we demonstrate in this paper. ACP is the application of the principles of agroecology to crop protection in order to promote virtuous and sustainable changes in agriculture and food systems. ACP combines multiple approaches and disciplines including ecology, agroecology, and Integrated Pest Management. It promotes a crop protection system compatible with healthy agricultural and food systems, agroecological principles and the “one health” approach. We predict that ACP will meet the challenge of pesticide-free agriculture in the future. In this paper, we will first present the scientific, agricultural and social components of ACP. We will then analyze the research approaches, questions, methods and tools needed to adopt ACP. Finally, we suggest key mechanisms to facilitate the transition to ACP, which will ultimately provide sustainable food, feed, and fuel in a context of major global change.
- Published
- 2023
- Full Text
- View/download PDF
7. Irreversible malarial retinopathy in a returning adult traveler to Marseille, France.
- Author
-
Diallo, Amadou Daye, Desfeux, Victor, Stolowy, Natacha, L'Ollivier, Coralie, Javelle, Emilie, David, Thierry, and Cassir, Nadim
- Published
- 2023
- Full Text
- View/download PDF
8. Monkeypox clinical disease: Literature review and a tool proposal for the monitoring of cases and contacts.
- Author
-
Javelle, Emilie, Ficko, Cécile, Savini, Hélène, Mura, Marie, Ferraris, Olivier, Tournier, Jean Nicolas, and de Laval, Franck
- Abstract
The human monkeypox disease has mainly been described in Western and Central Africa. Since May 2022, the monkeypox virus has been spreading worldwide in a new epidemiological pattern, where cases result from person-to-person transmission, and develop clinically milder or less typical illness than during previous outbreaks in endemic areas. The newly-emerging monkeypox disease needs to be described over the long term, to improve cases definitions, to implement prompt control measures against epidemics, and to provide supportive care. Hence, we first conducted a review of historical and recent outbreaks to define the full clinical spectrum of the monkeypox disease and its course known so far. Then, we built a self-administrated questionnaire collecting daily symptoms of the monkeypox infection to follow cases and their contacts, even remotely. This tool will assist in the management of cases, the surveillance of contacts, and the conduct of clinical studies. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
9. Gardening in an urban farm: A way to reconnect citizens with the soil.
- Author
-
Scheromm, Pascale and Javelle, Aurélie
- Subjects
URBAN agriculture ,URBAN gardening ,URBAN gardens ,CITY dwellers ,SOILS - Abstract
Simultaneously perceived as places of agriculture, of nature, and of social ties, urban collective gardens and farms enable city dwellers to immerse themselves in gardening, to recover forgotten skills, to learn from nature and the environment. They reinstate the soil as a feature of the city by making it visible to the urban population, to whom it is often unknown. In this article, we focus on urban gardeners' representations of the soil in a city of south of France. These representations were analyzed through the lens of the relationships that gardeners develop with the soil as an element of nature. Our results highlight relations where the care ethic is central. They suggest that the practice and the extension of agroecological urban gardening, by placing city dwellers in physical, skilled contact with the soil, promise a reconfiguration of citizens' relationship with soil. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.