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We live in the era of large data analysis, where processing vast datasets has become essential for uncovering valuable insights across various domains of our lives. Machine learning (ML) algorithms offer powerful tools for processing and analyzing this abundance of information. However, the considerable time and computational resources needed for training ML models pose significant challenges, especially within cascade schemes, due to the iterative nature of training algorithms, the complexity of feature extraction and transformation processes, and the large sizes of the datasets involved. This paper proposes a modification to the existing ML-based cascade scheme for analyzing large biomedical datasets by incorporating principal component analysis (PCA) at each level of the cascade. We selected the number of principal components to replace the initial inputs so that it ensured 95% variance retention. Furthermore, we enhanced the training and application algorithms and demonstrated the effectiveness of the modified cascade scheme through comparative analysis, which showcased a significant reduction in training time while improving the generalization properties of the method and the accuracy of the large data analysis. The improved enhanced generalization properties of the scheme stemmed from the reduction in nonsignificant independent attributes in the dataset, which further enhanced its performance in intelligent large data analysis. [ABSTRACT FROM AUTHOR]

Today, the field of biomedical engineering spans numerous areas of scientific research that grapple with the challenges of intelligent analysis of small datasets. Analyzing such datasets with existing artificial intelligence tools is a complex task, often complicated by issues like overfitting and other challenges inherent to machine learning methods and artificial neural networks. These challenges impose significant constraints on the practical application of these tools to the problem at hand. While data augmentation can offer some mitigation, existing methods often introduce their own set of limitations, reducing their overall effectiveness in solving the problem. In this paper, the authors present an improved neural network-based technology for predicting outcomes when analyzing small and extremely small datasets. This approach builds on the input doubling method, leveraging response surface linearization principles to improve performance. Detailed flowcharts of the improved technology's operations are provided, alongside descriptions of new preparation and application algorithms for the proposed solution. The modeling, conducted using two biomedical datasets with optimal parameters selected via differential evolution, demonstrated high prediction accuracy. A comparison with several existing methods revealed a significant reduction in various errors, underscoring the advantages of the improved neural network technology, which does not require training, for the analysis of extremely small biomedical datasets. [ABSTRACT FROM AUTHOR]

This document discusses the advancements in AI-based information technologies and their role in improving the quality and security of software and computer systems. It highlights the challenges faced in information processing and the need for specialized approaches in different industries. The document also presents several research contributions in areas such as malware detection, privacy-preserving anomaly detection, mobile application security evaluation, research paper recommendation systems, image encryption, and adaptive cyber defense. These contributions offer innovative solutions and demonstrate their effectiveness in addressing specific issues in the field of AI-based information technologies. [Extracted from the article]