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196 results on '"Holm, Hilma"'

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1. Integrative common and rare variant analyses provide insights into the genetic architecture of liver cirrhosis.

2. The correlation between CpG methylation and gene expression is driven by sequence variants

3. X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in genes regulated by androgen response elements.

4. Variant in the synaptonemal complex protein SYCE2 associates with pregnancy loss through effect on recombination

5. Genetic insights into resting heart rate and its role in cardiovascular disease.

6. Genetics and epidemiology of mutational barcode-defined clonal hematopoiesis

7. Rare variants with large effects provide functional insights into the pathology of migraine subtypes, with and without aura

8. Genome-wide association meta-analysis identifies risk loci for abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target

9. Large-scale plasma proteomics comparisons through genetics and disease associations

10. Author Correction: Large-scale plasma proteomics comparisons through genetics and disease associations

11. A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids

12. Physical and cognitive impact following SARS-CoV-2 infection in a large population-based case-control study

13. Publisher Correction: Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality

14. Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality

15. The power of genetic diversity in genome-wide association studies of lipids

16. Genome-wide meta-analysis identifies 93 risk loci and enables risk prediction equivalent to monogenic forms of venous thromboembolism

17. Complex effects of sequence variants on lipid levels and coronary artery disease

18. Abstract 18244: A Multi-Ancestry GWAS of Calcific Aortic Stenosis Among 2.7 Million Individuals

19. Abstract 16950: The Genetic Basis of Atrial Fibrillation in a Large-Scale Multi-Ancestry Sample

20. Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants

21. Multiomics study of nonalcoholic fatty liver disease

22. The sequences of 150,119 genomes in the UK Biobank

23. Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies

24. Reconstruction of a large-scale outbreak of SARS-CoV-2 infection in Iceland informs vaccination strategies

25. Genetic architecture of band neutrophil fraction in Iceland

26. HLA alleles, disease severity, and age associate with T-cell responses following infection with SARS-CoV-2

27. Population-level deficit of homozygosity unveils CPSF3 as an intellectual disability syndrome gene

28. Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals

29. Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis

30. Loss-of-function variants in ITSN1 confer high risk of Parkinson's disease.

31. Obesity Variants in the GIPR Gene Are not Associated With Risk of Fracture or Bone Mineral Density.

32. Large-scale integration of the plasma proteome with genetics and disease

33. Predicting the presence of coronary plaques featuring high-risk characteristics using polygenic risk scores and targeted proteomics in patients with suspected coronary artery disease

34. Genetic propensities for verbal and spatial ability have opposite effects on body mass index and risk of schizophrenia

35. Obesity Variants in the GIPRGene Are not Associated With Risk of Fracture or Bone Mineral Density

37. Obesity variants in the GIPR gene do not associate with risk of fracture or bone mineral density

38. Polygenic risk scores associate with blood pressure traits across the lifespan

39. Molecular benchmarks of a SARS-CoV-2 epidemic

40. The genetic architecture of age-related hearing impairment revealed by genome-wide association analysis

41. A genome-wide meta-analysis uncovers six sequence variants conferring risk of vertigo

42. Genetic variants associated with platelet count are predictive of human disease and physiological markers

43. Predicting the probability of death using proteomics

44. Combining Polygenic and Proteomic Risk Scores With Clinical Risk Factors to Improve Performance for Diagnosing Absence of Coronary Artery Disease in Patients With De Novo Chest Pain

45. Evaluation of Large-Scale Proteomics for Prediction of Cardiovascular Events

46. Screening for Rare Coding Variants That Associate With the QTc Interval in Iceland

47. Genetic Variants Close to TTN , NKX2-5 , and MYH6 Associate With AVNRT

48. Variants at the Interleukin 1 Gene Locus and Pericarditis

49. Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants

50. Polygenic risk score for ACE-inhibitor-associated cough based on the discovery of new genetic loci

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