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Your search keyword '"Hohmann, John G."' showing total 3 results
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3 results on '"Hohmann, John G."'

1. Cover Image, Volume 530, Issue 1

Author

Ding, Song‐Lin, primary, Royall, Joshua J., additional, Lesnar, Phil, additional, Facer, Benjamin A.C., additional, Smith, Kimberly A., additional, Wei, Yina, additional, Brouner, Kristina, additional, Dalley, Rachel A., additional, Dee, Nick, additional, Dolbeare, Tim A., additional, Ebbert, Amanda, additional, Glass, Ian A., additional, Keller, Nika H., additional, Lee, Felix, additional, Lemon, Tracy A., additional, Nyhus, Julie, additional, Pendergraft, Julie, additional, Reid, Robert, additional, Sarreal, Melaine, additional, Shapovalova, Nadiya V., additional, Szafer, Aaron, additional, Phillips, John W., additional, Sunkin, Susan M., additional, Hohmann, John G., additional, Jones, Allan R., additional, Hawrylycz, Michael J., additional, Hof, Patrick R., additional, Ng, Lydia, additional, Bernard, Amy, additional, and Lein, Ed S., additional

Published
2021
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2. Cellular resolution anatomical and molecular atlases for prenatal human brains

Author

Ding, Song‐Lin, primary, Royall, Joshua J., additional, Lesnar, Phil, additional, Facer, Benjamin A.C., additional, Smith, Kimberly A., additional, Wei, Yina, additional, Brouner, Kristina, additional, Dalley, Rachel A., additional, Dee, Nick, additional, Dolbeare, Tim A., additional, Ebbert, Amanda, additional, Glass, Ian A., additional, Keller, Nika H., additional, Lee, Felix, additional, Lemon, Tracy A., additional, Nyhus, Julie, additional, Pendergraft, Julie, additional, Reid, Robert, additional, Sarreal, Melaine, additional, Shapovalova, Nadiya V., additional, Szafer, Aaron, additional, Phillips, John W., additional, Sunkin, Susan M., additional, Hohmann, John G., additional, Jones, Allan R., additional, Hawrylycz, Michael J., additional, Hof, Patrick R., additional, Ng, Lydia, additional, Bernard, Amy, additional, and Lein, Ed S., additional

Published
2021
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3. Cellular resolution anatomical and molecular atlases for prenatal human brains.

Author

Ding SL, Royall JJ, Lesnar P, Facer BAC, Smith KA, Wei Y, Brouner K, Dalley RA, Dee N, Dolbeare TA, Ebbert A, Glass IA, Keller NH, Lee F, Lemon TA, Nyhus J, Pendergraft J, Reid R, Sarreal M, Shapovalova NV, Szafer A, Phillips JW, Sunkin SM, Hohmann JG, Jones AR, Hawrylycz MJ, Hof PR, Ng L, Bernard A, and Lein ES

Subjects
Animals, Female, Humans, Pregnancy, Atlases as Topic, Brain growth & development, Entorhinal Cortex growth & development, Hippocampus growth & development
Abstract

Increasing interest in studies of prenatal human brain development, particularly using new single-cell genomics and anatomical technologies to create cell atlases, creates a strong need for accurate and detailed anatomical reference atlases. In this study, we present two cellular-resolution digital anatomical atlases for prenatal human brain at postconceptional weeks (PCW) 15 and 21. Both atlases were annotated on sequential Nissl-stained sections covering brain-wide structures on the basis of combined analysis of cytoarchitecture, acetylcholinesterase staining, and an extensive marker gene expression dataset. This high information content dataset allowed reliable and accurate demarcation of developing cortical and subcortical structures and their subdivisions. Furthermore, using the anatomical atlases as a guide, spatial expression of 37 and 5 genes from the brains, respectively, at PCW 15 and 21 was annotated, illustrating reliable marker genes for many developing brain structures. Finally, the present study uncovered several novel developmental features, such as the lack of an outer subventricular zone in the hippocampal formation and entorhinal cortex, and the apparent extension of both cortical (excitatory) and subcortical (inhibitory) progenitors into the prenatal olfactory bulb. These comprehensive atlases provide useful tools for visualization, segmentation, targeting, imaging, and interpretation of brain structures of prenatal human brain, and for guiding and interpreting the next generation of cell census and connectome studies., (© 2021 Wiley Periodicals LLC.)

Published
2022
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