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Click here for the corresponding questions to this CME article. [ABSTRACT FROM AUTHOR]

Patient (F5-1) had a cirrhosis at the age of 34 years (after 12 years of OR), but liver blood parameters remained stable during the 31 years of follow-up. Before introducing OR, all also had liver anomalies, that consisted in either increased liver enzymes, hyper echogenic liver, hepatosplenomaly or cirrhosis for one patient (F6-1). In conclusion, awaiting future targeted therapy for DCS or prospective monitoring studies, there is no safety signal to contraindicate OR in CDS patients with disabling skin anomalies, on condition that a close monitoring is performed. [Extracted from the article]

In this study a close to reality one component (1K) structural epoxy adhesive is introduced. The physical properties have been investigated by means of gravimetric water uptake, bulk tensile tests, and lap shear tests. The influence of two different types of hollow glass microspheres (HGM) on the ageing behaviour has been observed via accelerated ageing tests followed by lap shear tests of galvanized steel. Results show that the formulation described outperforms very brittle and basic systems consisting of bisphenol A diglycidyl ether (DGEBA) and dicyandiamide (DICY) in terms of ductility. The addition of HGM resulted in higher water absorption suggesting that water gathers as a liquid in the HGM. Further, the addition of HGM led to an increase of the cohesion failure percentage on unaged lap shear specimens without significantly influencing the tensile shear strength and the addition of the bigger HGM observed led to a change in fracture mechanism from substrate-near cohesion failure to cohesion failure. The results of this study on the long-term durability of bonded steel joints indicate that the addition of HGM into the adhesive system has no significant effect on the ageing behaviour in two of three corrosion tests. It can be concluded that the incorporation of HGM is a possible solution not only reducing the amount of chemicals required for automotive adhesive production, but also promoting lightweight construction because of the decreased density of the adhesive system. • A novel, near to realism structural epoxy adhesive for scientific purposes. • Gravimetric water uptake in structural epoxy adhesive. • Ageing resistance of adhesively bonded steel sheets. • Addition of hollow glass microspheres changes fracture mechanism. [ABSTRACT FROM AUTHOR]

Linked Article: Valentin et al. Br J Dermatol 2021; 184:1123–1131. [ABSTRACT FROM AUTHOR]

The article demonstrate that New Caledonian crows are an excellent candidate for testing the conservative criteria for mental time travel with the details of the experiment and interpretation accurately. Topics include actual task complexity by ignoring key aspects of the cognitive process required in the experiment; and promising avenue for resolving the many antagonistic debates within comparative psychology.