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1. Temporal Trends in Takotsubo Syndrome: Results From the International Takotsubo Registry

Author

Schweiger, Victor, Cammann, Victoria L., Crisci, Giulia, Gilhofer, Thomas, Schlenker, Rabea, Niederseer, David, Chen, Shaojie, Ebrahimi, Ramin, Wenzl, Florian, Würdinger, Michael, Citro, Rodolfo, Vecchione, Carmine, Gili, Sebastiano, Neuhaus, Michael, Franke, Jennifer, Meder, Benjamin, Jaguszewski, Miłosz, Noutsias, Michel, Knorr, Maike, Jansen, Thomas, D’Ascenzo, Fabrizio, Dichtl, Wolfgang, von Lewinski, Dirk, Burgdorf, Christof, Kherad, Behrouz, Tschöpe, Carsten, Sarcon, Annahita, Shinbane, Jerold, Rajan, Lawrence, Michels, Guido, Pfister, Roman, Cuneo, Alessandro, Jacobshagen, Claudius, Karakas, Mahir, Koenig, Wolfgang, Pott, Alexander, Meyer, Philippe, Roffi, Marco, Banning, Adrian, Wolfrum, Mathias, Cuculi, Florim, Kobza, Richard, Fischer, Thomas A., Vasankari, Tuija, Airaksinen, K.E. Juhani, Napp, L. Christian, Dworakowski, Rafal, MacCarthy, Philip, Kaiser, Christoph, Osswald, Stefan, Galiuto, Leonarda, Chan, Christina, Bridgman, Paul, Beug, Daniel, Delmas, Clément, Lairez, Olivier, Gilyarova, Ekaterina, Shilova, Alexandra, Gilyarov, Mikhail, El-Battrawy, Ibrahim, Akin, Ibrahim, Poledniková, Karolina, Toušek, Petr, Winchester, David E., Massoomi, Michael, Galuszka, Jan, Ukena, Christian, Poglajen, Gregor, Carrilho-Ferreira, Pedro, Hauck, Christian, Paolini, Carla, Bilato, Claudio, Kobayashi, Yoshio, Kato, Ken, Ishibashi, Iwao, Himi, Toshiharu, Din, Jehangir, Al-Shammari, Ali, Prasad, Abhiram, Rihal, Charanjit S., Liu, Kan, Schulze, P. Christian, Bianco, Matteo, Jörg, Lucas, Rickli, Hans, Pestana, Gonçalo, Nguyen, Thanh H., Böhm, Michael, Maier, Lars S., Pinto, Fausto J., Widimský, Petr, Felix, Stephan B., Braun-Dullaeus, Ruediger C., Rottbauer, Wolfgang, Hasenfuß, Gerd, Pieske, Burkert M., Schunkert, Heribert, Budnik, Monika, Opolski, Grzegorz, Thiele, Holger, Bauersachs, Johann, Horowitz, John D., Di Mario, Carlo, Kong, William, Dalakoti, Mayank, Imori, Yoichi, Münzel, Thomas, Liberale, Luca, Montecucco, Fabrizio, Bax, Jeroen J., Crea, Filippo, Ruschitzka, Frank, Lüscher, Thomas F., Ghadri, Jelena R., Bossone, Eduardo, Templin, Christian, and Di Vece, Davide

Published
2024
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2. Author Correction: Optical coherence tomography in coronary atherosclerosis assessment and intervention

Author

Araki, Makoto, Park, Seung-Jung, Dauerman, Harold L., Uemura, Shiro, Kim, Jung-Sun, Di Mario, Carlo, Johnson, Thomas W., Guagliumi, Giulio, Kastrati, Adnan, Joner, Michael, Holm, Niels Ramsing, Alfonso, Fernando, Wijns, William, Adriaenssens, Tom, Nef, Holger, Rioufol, Gilles, Amabile, Nicolas, Souteyrand, Geraud, Meneveau, Nicolas, Gerbaud, Edouard, Opolski, Maksymilian P., Gonzalo, Nieves, Tearney, Guillermo J., Bouma, Brett, Aguirre, Aaron D., Mintz, Gary S., Stone, Gregg W., Bourantas, Christos V., Räber, Lorenz, Gili, Sebastiano, Mizuno, Kyoichi, Kimura, Shigeki, Shinke, Toshiro, Hong, Myeong-Ki, Jang, Yangsoo, Cho, Jin Man, Yan, Bryan P., Porto, Italo, Niccoli, Giampaolo, Montone, Rocco A., Thondapu, Vikas, Papafaklis, Michail I., Michalis, Lampros K., Reynolds, Harmony, Saw, Jacqueline, Libby, Peter, Weisz, Giora, Iannaccone, Mario, Gori, Tommaso, Toutouzas, Konstantinos, Yonetsu, Taishi, Minami, Yoshiyasu, Takano, Masamichi, Raffel, O. Christopher, Kurihara, Osamu, Soeda, Tsunenari, Sugiyama, Tomoyo, Kim, Hyung Oh, Lee, Tetsumin, Higuma, Takumi, Nakajima, Akihiro, Yamamoto, Erika, Bryniarski, Krzysztof L., Di Vito, Luca, Vergallo, Rocco, Fracassi, Francesco, Russo, Michele, Seegers, Lena M., McNulty, Iris, Park, Sangjoon, Feldman, Marc, Escaned, Javier, Prati, Francesco, Arbustini, Eloisa, Pinto, Fausto J., Waksman, Ron, Garcia-Garcia, Hector M., Maehara, Akiko, Ali, Ziad, Finn, Aloke V., Virmani, Renu, Kini, Annapoorna S., Daemen, Joost, Kume, Teruyoshi, Hibi, Kiyoshi, Tanaka, Atsushi, Akasaka, Takashi, Kubo, Takashi, Yasuda, Satoshi, Croce, Kevin, Granada, Juan F., Lerman, Amir, Prasad, Abhiram, Regar, Evelyn, Saito, Yoshihiko, Sankardas, Mullasari Ajit, Subban, Vijayakumar, Weissman, Neil J., Chen, Yundai, Yu, Bo, Nicholls, Stephen J., Barlis, Peter, West, Nick E. J., Arbab-Zadeh, Armin, Ye, Jong Chul, Dijkstra, Jouke, Lee, Hang, Narula, Jagat, Crea, Filippo, Nakamura, Sunao, Kakuta, Tsunekazu, Fujimoto, James, Fuster, Valentin, and Jang, Ik-Kyung

Published
2024
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4. Comparison of Outcomes Between 1- and 2-Stent Techniques for Medina Classification 0.0.1 Coronary Bifurcation Lesions

Author

Choi, Ki Hong, Bruno, Francesco, Cho, Yun-Kyeong, De Luca, Leonardo, Song, Young Bin, Kang, Jeehoon, Mattesini, Alessio, Gwon, Hyeon-Cheol, Truffa, Alessandra, Kim, Hyo-Soo, Wańha, Wojciech, Chun, Woo Jung, Gili, Sebastiano, Hur, Seung-Ho, Helft, Gerard, Han, Seung Hwan, Cortese, Bernardo, Lee, Cheol Hyun, Escaned, Javier, Yoon, Hyuck-Jun, Chieffo, Alaide, Hahn, Joo-Yong, Gallone, Guglielmo, Choi, Seung-Hyuk, De Ferrari, Gaetano, Koo, Bon-Kwon, Quadri, Giorgio, D’Ascenzo, Fabrizio, Nam, Chang-Wook, and de Filippo, Ovidio

Published
2023
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6. Diagnostic accuracy of subendocardial vs. transmural myocardial perfusion defect for the detection of in-stent restenosis or progression of coronary artery disease after percutaneous coronary intervention

Author

Mushtaq, Saima, Pontone, Gianluca, Conte, Edoardo, Trabattoni, Daniela, Galli, Stefano, Gili, Sebastiano, Troiano, Sarah, Teruzzi, Giovanni, Baggiano, Andrea, Bonomi, Alice, Mallia, Vincenzo, Marchetti, Davide, Schillaci, Matteo, Melotti, Eleonora, Belmonte, Marta, Guaricci, Andrea Igoren, Gigante, Carlo, Pepi, Mauro, Bartorelli, Antonio L., and Andreini, Daniele

Published
2023
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7. Optical coherence tomography in coronary atherosclerosis assessment and intervention

Author

Araki, Makoto, Park, Seung-Jung, Dauerman, Harold L., Uemura, Shiro, Kim, Jung-Sun, Di Mario, Carlo, Johnson, Thomas W., Guagliumi, Giulio, Kastrati, Adnan, Joner, Michael, Holm, Niels Ramsing, Alfonso, Fernando, Wijns, William, Adriaenssens, Tom, Nef, Holger, Rioufol, Gilles, Amabile, Nicolas, Souteyrand, Geraud, Meneveau, Nicolas, Gerbaud, Edouard, Opolski, Maksymilian P., Gonzalo, Nieves, Tearney, Guillermo J., Bouma, Brett, Aguirre, Aaron D., Mintz, Gary S., Stone, Gregg W., Bourantas, Christos V., Räber, Lorenz, Gili, Sebastiano, Mizuno, Kyoichi, Kimura, Shigeki, Shinke, Toshiro, Hong, Myeong-Ki, Jang, Yangsoo, Cho, Jin Man, Yan, Bryan P., Porto, Italo, Niccoli, Giampaolo, Montone, Rocco A., Thondapu, Vikas, Papafaklis, Michail I., Michalis, Lampros K., Reynolds, Harmony, Saw, Jacqueline, Libby, Peter, Weisz, Giora, Iannaccone, Mario, Gori, Tommaso, Toutouzas, Konstantinos, Yonetsu, Taishi, Minami, Yoshiyasu, Takano, Masamichi, Raffel, O. Christopher, Kurihara, Osamu, Soeda, Tsunenari, Sugiyama, Tomoyo, Kim, Hyung Oh, Lee, Tetsumin, Higuma, Takumi, Nakajima, Akihiro, Yamamoto, Erika, Bryniarski, Krzysztof L., Di Vito, Luca, Vergallo, Rocco, Fracassi, Francesco, Russo, Michele, Seegers, Lena M., McNulty, Iris, Park, Sangjoon, Feldman, Marc, Escaned, Javier, Prati, Francesco, Arbustini, Eloisa, Pinto, Fausto J., Waksman, Ron, Garcia-Garcia, Hector M., Maehara, Akiko, Ali, Ziad, Finn, Aloke V., Virmani, Renu, Kini, Annapoorna S., Daemen, Joost, Kume, Teruyoshi, Hibi, Kiyoshi, Tanaka, Atsushi, Akasaka, Takashi, Kubo, Takashi, Yasuda, Satoshi, Croce, Kevin, Granada, Juan F., Lerman, Amir, Prasad, Abhiram, Regar, Evelyn, Saito, Yoshihiko, Sankardas, Mullasari Ajit, Subban, Vijayakumar, Weissman, Neil J., Chen, Yundai, Yu, Bo, Nicholls, Stephen J., Barlis, Peter, West, Nick E. J., Arbab-Zadeh, Armin, Ye, Jong Chul, Dijkstra, Jouke, Lee, Hang, Narula, Jagat, Crea, Filippo, Nakamura, Sunao, Kakuta, Tsunekazu, Fujimoto, James, Fuster, Valentin, and Jang, Ik-Kyung

Published
2022
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8. Impact of Clinical and Lesion Features on Outcomes After Percutaneous Coronary Intervention in Bifurcation Lesions

Author

Kang, Jeehoon, Bruno, Francesco, Rhee, Tae-min, De Luca, Leonardo, Han, Jung-Kyu, de Filippo, Ovidio, Yang, Han-Mo, Mattesini, Alessio, Park, Kyung Woo, Truffa, Alessandra, Kim, Hyo-Soo, Wanha, Wojciech, Gwon, Hyeon-Cheol, Gili, Sebastiano, Chun, Woo Jung, Helft, Gerard, Hur, Seung-Ho, Cortese, Bernardo, Han, Seung Hwan, Escaned, Javier, Song, Young Bin, Chieffo, Alaide, Choi, Ki Hong, Gallone, Guglielmo, Doh, Joon-Hyung, De Ferrari, Gaetano, Hong, Soon-Jun, Quadri, Giorgio, Nam, Chang-Wook, Koo, Bon-Kwon, and D’Ascenzo, Fabrizio

Published
2022
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9. Ischemic-hemorrhagic balance in diabetic and non-diabetic patients after acute coronary syndrome

Author

Domínguez-Rodríguez, Luis Manuel, Raposeiras-Roubín, Sergio, Abu-Assi, Emad, Cespón-Fernández, María, Melendo-Viu, María, D’Ascenzo, Fabrizio, Kinnaird, Tim, Ariza-Solé, Albert, Manzano-Fernández, Sergio, Templin, Christian, Velicki, Lazar, Xanthopoulou, Ioanna, Cerrato, Enrico, Quadri, Giorgio, Rognoni, Andrea, Boccuzzi, Giacome, Montabone, Andrea, Taha, Salma, Durante, Alessandro, Gili, Sebastiano, Magnani, Giulia, Autelli, Michele, Grosso, Alberto, Flores-Blanco, Pedro, Garay, Alberto, Varbella, Ferdinando, Tommassini, Francesco, Gallo, Diego, Morbiducci, Umberto, Domínguez-Rodríguez, Alberto, Valdés, Mariano, Cequier, Ángel, Gaita, Fiorenzo, Alexopoulos, Dimitrios, and Íñiguez-Romo, Andrés

Published
2022
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10. Ethnic comparison in takotsubo syndrome: novel insights from the International Takotsubo Registry

Author

Imori, Yoichi, Kato, Ken, Cammann, Victoria L., Szawan, Konrad A., Wischnewsky, Manfred, Dreiding, Sara, Würdinger, Michael, Schönberger, Maximilian, Petkova, Vanya, Niederseer, David, Levinson, Rena A., Di Vece, Davide, Gili, Sebastiano, Seifert, Burkhardt, Wakita, Masaki, Suzuki, Noriko, Citro, Rodolfo, Bossone, Eduardo, Heiner, Susanne, Knorr, Maike, Jansen, Thomas, Münzel, Thomas, D’Ascenzo, Fabrizio, Franke, Jennifer, Sorici-Barb, Ioana, Katus, Hugo A., Sarcon, Annahita, Shinbane, Jerold, Napp, L. Christian, Bauersachs, Johann, Jaguszewski, Milosz, Shiomura, Reiko, Nakamura, Shunichi, Takano, Hitoshi, Noutsias, Michel, Burgdorf, Christof, Ishibashi, Iwao, Himi, Toshiharu, Koenig, Wolfgang, Schunkert, Heribert, Thiele, Holger, Kherad, Behrouz, Tschöpe, Carsten, Pieske, Burkert M., Rajan, Lawrence, Michels, Guido, Pfister, Roman, Mizuno, Shingo, Cuneo, Alessandro, Jacobshagen, Claudius, Hasenfuß, Gerd, Karakas, Mahir, Mochizuki, Hiroki, Pott, Alexander, Rottbauer, Wolfgang, Said, Samir M., Braun-Dullaeus, Ruediger C., Banning, Adrian, Isogai, Toshiaki, Kimura, Akihisa, Cuculi, Florim, Kobza, Richard, Fischer, Thomas A., Vasankari, Tuija, Airaksinen, K. E. Juhani, Tomita, Yasuhiro, Budnik, Monika, Opolski, Grzegorz, Dworakowski, Rafal, MacCarthy, Philip, Kaiser, Christoph, Osswald, Stefan, Galiuto, Leonarda, Crea, Filippo, Dichtl, Wolfgang, Murakami, Tsutomu, Ikari, Yuji, Empen, Klaus, Beug, Daniel, Felix, Stephan B., Delmas, Clément, Lairez, Olivier, Yamaguchi, Tetsuo, El-Battrawy, Ibrahim, Akin, Ibrahim, Borggrefe, Martin, Horowitz, John D., Kozel, Martin, Tousek, Petr, Widimský, Petr, Gilyarova, Ekaterina, Shilova, Alexandra, Gilyarov, Mikhail, Neuhaus, Michael, Meyer, Philippe, Arroja, Jose David, Chan, Christina, Bridgman, Paul, Galuszka, Jan, Poglajen, Gregor, Carrilho-Ferreira, Pedro, Pinto, Fausto J., Hauck, Christian, Maier, Lars S., Liu, Kan, Di Mario, Carlo, Paolini, Carla, Bilato, Claudio, Bianco, Matteo, Jörg, Lucas, Rickli, Hans, Winchester, David E., Ukena, Christian, Böhm, Michael, Bax, Jeroen J., Prasad, Abhiram, Rihal, Charanjit S., Saito, Shigeru, Kobayashi, Yoshio, Lüscher, Thomas F., Ruschitzka, Frank, Shimizu, Wataru, Ghadri, Jelena R., and Templin, Christian

Published
2022
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11. Cardiac biomarkers for diagnosing Takotsubo syndrome

Author

Schweiger, Victor, primary, Di Vece, Davide, additional, Cammann, Victoria L, additional, Koleva, Iva, additional, Würdinger, Michael, additional, Gilhofer, Thomas, additional, Rajman, Katja, additional, Szawan, Konrad A, additional, Niederseer, David, additional, Citro, Rodolfo, additional, Vecchione, Carmine, additional, Bossone, Eduardo, additional, Gili, Sebastiano, additional, Neuhaus, Michael, additional, Franke, Jennifer, additional, Meder, Benjamin, additional, Jaguszewski, Miłosz, additional, Noutsias, Michel, additional, Knorr, Maike, additional, Jansen, Thomas, additional, D’Ascenzo, Fabrizio, additional, Bruno, Francesco, additional, De Filippo, Ovidio, additional, Stefanini, Giulio, additional, Campo, Gianluca, additional, Wanha, Wojciech, additional, Roubin, Sergio Raposeiras, additional, Dichtl, Wolfgang, additional, von Lewinski, Dirk, additional, Burgdorf, Christof, additional, Kherad, Behrouz, additional, Tschöpe, Carsten, additional, Sarcon, Annahita, additional, Shinbane, Jerold, additional, Rajan, Lawrence, additional, Michels, Guido, additional, Pfister, Roman, additional, Cuneo, Alessandro, additional, Jacobshagen, Claudius, additional, Karakas, Mahir, additional, Koenig, Wolfgang, additional, Pott, Alexander, additional, Meyer, Philippe, additional, Roffi, Marco, additional, Banning, Adrian, additional, Wolfrum, Mathias, additional, Cuculi, Florim, additional, Kobza, Richard, additional, Fischer, Thomas A, additional, Vasankari, Tuija, additional, Airaksinen, K E Juhani, additional, Napp, L Christian, additional, Dworakowski, Rafal, additional, MacCarthy, Philip, additional, Kaiser, Christoph, additional, Osswald, Stefan, additional, Galiuto, Leonarda, additional, Chan, Christina, additional, Bridgman, Paul, additional, Beug, Daniel, additional, Delmas, Clément, additional, Lairez, Olivier, additional, Gilyarova, Ekaterina, additional, Shilova, Alexandra, additional, Gilyarov, Mikhail, additional, El-Battrawy, Ibrahim, additional, Akin, Ibrahim, additional, Poledniková, Karolina, additional, Toušek, Petr, additional, Winchester, David E, additional, Massoomi, Michael, additional, Galuszka, Jan, additional, Ukena, Christian, additional, Poglajen, Gregor, additional, Carrilho-Ferreira, Pedro, additional, Hauck, Christian, additional, Paolini, Carla, additional, Bilato, Claudio, additional, Kobayashi, Yoshio, additional, Kato, Ken, additional, Ishibashi, Iwao, additional, Himi, Toshiharu, additional, Din, Jehangir, additional, Al-Shammari, Ali, additional, Prasad, Abhiram, additional, Rihal, Charanjit S, additional, Liu, Kan, additional, Schulze, P Christian, additional, Bianco, Matteo, additional, Jörg, Lucas, additional, Rickli, Hans, additional, Pestana, Gonçalo, additional, Nguyen, Thanh H, additional, Böhm, Michael, additional, Maier, Lars S, additional, Pinto, Fausto J, additional, Widimský, Petr, additional, Felix, Stephan B, additional, Braun-Dullaeus, Ruediger C, additional, Rottbauer, Wolfgang, additional, Hasenfuß, Gerd, additional, Pieske, Burkert M, additional, Schunkert, Heribert, additional, Budnik, Monika, additional, Opolski, Grzegorz, additional, Thiele, Holger, additional, Bauersachs, Johann, additional, Horowitz, John D, additional, Di Mario, Carlo, additional, Kong, William, additional, Dalakoti, Mayank, additional, Imori, Yoichi, additional, Münzel, Thomas, additional, Bax, Jeroen J, additional, Lüscher, Thomas F, additional, Crea, Filippo, additional, Ruschitzka, Frank, additional, Ghadri, Jelena R, additional, and Templin, Christian, additional

Published
2024
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12. Patent Foramen Ovale Occlusion in Elderly Patients: Is It Worth It? A Large, Single-Center Retrospective Analysis.

Author

Gili, Sebastiano, Calligaris, Giuseppe, Teruzzi, Giovanni, Santagostino Baldi, Giulia, Muratori, Manuela, Montorsi, Piero, and Trabattoni, Daniela

Subjects
*OLDER patients, *PATENT foramen ovale, *ISCHEMIC stroke, *ATRIAL fibrillation, *STROKE patients, *THERAPEUTIC embolization
Abstract

Background: Patent foramen ovale (PFO) is often diagnosed in patients with cryptogenic stroke, aged > 60–65 years, but few data report the outcomes of PFO closure in elderly patients. Methods: Consecutive patients undergoing PFO closure at a single institution between January 2006 and December 2011 were included. Baseline clinical features and cerebral imaging data were collected, and a RoPE score was calculated for each patient. Procedural data were recorded as well as medical therapy upon discharge. All-cause death, ischemic stroke, TIA and systemic embolism recurrence at long-term follow-up were investigated, as well as new atrial fibrillation onset. Results: Overall, 462 patients were included, of whom 64 (13.8%) were aged ≥ 65 years. Female gender was slightly more prevalent in the younger group while hypertension was more frequent among elderly patients. Previous stroke/TIA was the indication for PFO closure in 95.3% of older patients and 80.4% of younger patients, whereas other indications were more frequent among younger patients. RoPE scores were lower in older patients (median RoPE score of 5 vs. 7), and atrial septal aneurysm was more frequently detected among elderly patients. All procedures were technically successful. Procedural or in-hospital complications equally occurred in 5 (7.8%) older patients (4 AF and 1 device embolization) and 30 (7.5%) young patients (29 AF or other supraventricular arrhythmias and 1 device embolization). The follow-up duration was longer among younger patients. All-cause mortality was higher in older patients (16 deaths vs. 4 at follow-up, log-rank p < 0.001), no recurrent strokes occurred, and 2 TIAs were reported among non-elderly patients. New-onset atrial fibrillation occurred in three elderly and eight young patients. Conclusions: PFO closure is a safe procedure in patients aged ≥ 65 years, associated with favorable long-term follow-up and the prevention of ischemic neurologic recurrences. [ABSTRACT FROM AUTHOR]

Published
2024
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13. Plasma Exosomes Refl Ect Myocardial Injury Detected by Cardiac Magnetic Resonance in STEMI Patients

Author

Baggiano, Andrea, primary, Zarà, Marta, additional, Banfi, Cristina, additional, Campodonico, Jeness, additional, Tedesco, Calogero, additional, Amadio, Patrizia, additional, Gili, Sebastiano, additional, Dona, Gianluca De, additional, Sandrini, Leonardo, additional, Maragna, Riccardo, additional, Junod, Daniele, additional, Fusini, Laura, additional, Mushtaq, Saima, additional, Fazzari, Fabio, additional, Marenzi, Giancarlo, additional, Pontone, Gianluca, additional, and Barbieri, Silvia, additional

Published
2024
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14. Circulating plasma exosomes reflect the severity of myocardial damage in STEMI patients

Author

Zarà, Marta, primary, Baggiano, Andrea, primary, Amadio, Patrizia, primary, Campodonico, Jeness, primary, Gili, Sebastiano, primary, Annoni, Andrea, primary, De Dona, Gianluca, primary, Carerj, Maria Ludovica, primary, Cilia, Francesco, primary, Formenti, Alberto, primary, Fusini, Laura, primary, Banfi, Cristina, primary, Gripari, Paola, primary, Tedesco, Calogero Claudio, primary, Mancini, Maria Elisabetta, primary, Chiesa, Mattia, primary, Maragna, Riccardo, primary, Marchetti, Francesca, primary, Penso, Marco, primary, Tassetti, Luigi, primary, Volpe, Alessandra, primary, Bonomi, Alice, primary, Marenzi, Giancarlo, primary, Pontone, Gianluca, primary, and Barbieri, Silvia Stella, primary

Published
2023
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16. Circulating Small Extracellular Vesicles Reflect the Severity of Myocardial Damage in STEMI Patients

Author

Zarà, Marta, primary, Baggiano, Andrea, additional, Amadio, Patrizia, additional, Campodonico, Jeness, additional, Gili, Sebastiano, additional, Annoni, Andrea, additional, De Dona, Gianluca, additional, Carerj, Maria Ludovica, additional, Cilia, Francesco, additional, Formenti, Alberto, additional, Fusini, Laura, additional, Banfi, Cristina, additional, Gripari, Paola, additional, Tedesco, Calogero Claudio, additional, Mancini, Maria Elisabetta, additional, Chiesa, Mattia, additional, Maragna, Riccardo, additional, Marchetti, Francesca, additional, Penso, Marco, additional, Tassetti, Luigi, additional, Volpe, Alessandra, additional, Bonomi, Alice, additional, Marenzi, Giancarlo, additional, Pontone, Gianluca, additional, and Barbieri, Silvia Stella, additional

Published
2023
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17. Machine learning‐based prediction of in‐hospital death for patients with takotsubo syndrome: The InterTAK‐ML model

Author

De Filippo, Ovidio, primary, Cammann, Victoria L., additional, Pancotti, Corrado, additional, Di Vece, Davide, additional, Silverio, Angelo, additional, Schweiger, Victor, additional, Niederseer, David, additional, Szawan, Konrad A., additional, Würdinger, Michael, additional, Koleva, Iva, additional, Dusi, Veronica, additional, Bellino, Michele, additional, Vecchione, Carmine, additional, Parodi, Guido, additional, Bossone, Eduardo, additional, Gili, Sebastiano, additional, Neuhaus, Michael, additional, Franke, Jennifer, additional, Meder, Benjamin, additional, Jaguszewski, Miłosz, additional, Noutsias, Michel, additional, Knorr, Maike, additional, Jansen, Thomas, additional, Dichtl, Wolfgang, additional, von Lewinski, Dirk, additional, Burgdorf, Christof, additional, Kherad, Behrouz, additional, Tschöpe, Carsten, additional, Sarcon, Annahita, additional, Shinbane, Jerold, additional, Rajan, Lawrence, additional, Michels, Guido, additional, Pfister, Roman, additional, Cuneo, Alessandro, additional, Jacobshagen, Claudius, additional, Karakas, Mahir, additional, Koenig, Wolfgang, additional, Pott, Alexander, additional, Meyer, Philippe, additional, Roffi, Marco, additional, Banning, Adrian, additional, Wolfrum, Mathias, additional, Cuculi, Florim, additional, Kobza, Richard, additional, Fischer, Thomas A., additional, Vasankari, Tuija, additional, Airaksinen, K.E. Juhani, additional, Napp, L. Christian, additional, Dworakowski, Rafal, additional, MacCarthy, Philip, additional, Kaiser, Christoph, additional, Osswald, Stefan, additional, Galiuto, Leonarda, additional, Chan, Christina, additional, Bridgman, Paul, additional, Beug, Daniel, additional, Delmas, Clément, additional, Lairez, Olivier, additional, Gilyarova, Ekaterina, additional, Shilova, Alexandra, additional, Gilyarov, Mikhail, additional, El‐Battrawy, Ibrahim, additional, Akin, Ibrahim, additional, Poledniková, Karolina, additional, Toušek, Petr, additional, Winchester, David E., additional, Massoomi, Michael, additional, Galuszka, Jan, additional, Ukena, Christian, additional, Poglajen, Gregor, additional, Carrilho‐Ferreira, Pedro, additional, Hauck, Christian, additional, Paolini, Carla, additional, Bilato, Claudio, additional, Kobayashi, Yoshio, additional, Kato, Ken, additional, Ishibashi, Iwao, additional, Himi, Toshiharu, additional, Din, Jehangir, additional, Al‐Shammari, Ali, additional, Prasad, Abhiram, additional, Rihal, Charanjit S., additional, Liu, Kan, additional, Schulze, P. Christian, additional, Bianco, Matteo, additional, Jörg, Lucas, additional, Rickli, Hans, additional, Pestana, Gonçalo, additional, Nguyen, Thanh H., additional, Böhm, Michael, additional, Maier, Lars S., additional, Pinto, Fausto J., additional, Widimský, Petr, additional, Felix, Stephan B., additional, Braun‐Dullaeus, Ruediger C., additional, Rottbauer, Wolfgang, additional, Hasenfuß, Gerd, additional, Pieske, Burkert M., additional, Schunkert, Heribert, additional, Budnik, Monika, additional, Opolski, Grzegorz, additional, Thiele, Holger, additional, Bauersachs, Johann, additional, Horowitz, John D., additional, Di Mario, Carlo, additional, Bruno, Francesco, additional, Kong, William, additional, Dalakoti, Mayank, additional, Imori, Yoichi, additional, Münzel, Thomas, additional, Crea, Filippo, additional, Lüscher, Thomas F., additional, Bax, Jeroen J., additional, Ruschitzka, Frank, additional, De Ferrari, Gaetano Maria, additional, Fariselli, Piero, additional, Ghadri, Jelena R., additional, Citro, Rodolfo, additional, D'Ascenzo, Fabrizio, additional, and Templin, Christian, additional

Published
2023
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18. In-hospital outcomes in nonagenarian patients undergoing primary percutaneous coronary intervention

Author

ANGELINI, Filippo, primary, FRANCHIN, Luca, additional, BOCCHINO, Pier P., additional, MORICI, Nuccia, additional, WAŃHA, Wojciech, additional, SAVONITTO, Stefano, additional, TRABATTONI, Daniela, additional, CERRATO, Enrico, additional, BARBIERI, Lucia, additional, FORTUNI, Federico, additional, DE LUCA, Leonardo, additional, GRECO, Antonio, additional, DE FILIPPO, Ovidio, additional, MONTEFUSCO, Antonio, additional, MONTABONE, Andrea, additional, RUBINO, Anna E., additional, GILI, Sebastiano, additional, QUADRI, Giorgio, additional, SOMASCHINI, Alberto, additional, CORNARA, Stefano, additional, CARUGO, Stefano, additional, CAPODANNO, Davide, additional, WOJAKOWSKI, Wojciech, additional, DUSI, Veronica, additional, D’ASCENZO, Fabrizio, additional, and DE FERRARI, Gaetano M., additional

Published
2023
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20. Machine learning-based prediction of in-hospital death for patients with takotsubo syndrome: The InterTAK-ML model

Author

De Filippo, Ovidio, Cammann, Victoria L; https://orcid.org/0000-0001-7240-6593, Pancotti, Corrado, Di Vece, Davide, Silverio, Angelo, Schweiger, Victor, Niederseer, David; https://orcid.org/0000-0003-3089-1222, Szawan, Konrad A, Würdinger, Michael, Koleva, Iva, Dusi, Veronica, Bellino, Michele, Vecchione, Carmine, Parodi, Guido, Bossone, Eduardo, Gili, Sebastiano; https://orcid.org/0000-0002-0542-0448, Neuhaus, Michael, Franke, Jennifer, Meder, Benjamin, Jaguszewski, Miłosz, Noutsias, Michel, Knorr, Maike, Jansen, Thomas, Dichtl, Wolfgang, von Lewinski, Dirk; https://orcid.org/0000-0001-9996-6128, Burgdorf, Christof, Kherad, Behrouz, Tschöpe, Carsten, Sarcon, Annahita, Lüscher, Thomas F; https://orcid.org/0000-0002-5259-538X, et al, De Filippo, Ovidio, Cammann, Victoria L; https://orcid.org/0000-0001-7240-6593, Pancotti, Corrado, Di Vece, Davide, Silverio, Angelo, Schweiger, Victor, Niederseer, David; https://orcid.org/0000-0003-3089-1222, Szawan, Konrad A, Würdinger, Michael, Koleva, Iva, Dusi, Veronica, Bellino, Michele, Vecchione, Carmine, Parodi, Guido, Bossone, Eduardo, Gili, Sebastiano; https://orcid.org/0000-0002-0542-0448, Neuhaus, Michael, Franke, Jennifer, Meder, Benjamin, Jaguszewski, Miłosz, Noutsias, Michel, Knorr, Maike, Jansen, Thomas, Dichtl, Wolfgang, von Lewinski, Dirk; https://orcid.org/0000-0001-9996-6128, Burgdorf, Christof, Kherad, Behrouz, Tschöpe, Carsten, Sarcon, Annahita, Lüscher, Thomas F; https://orcid.org/0000-0002-5259-538X, and et al

Abstract

AIMS Takotsubo syndrome (TTS) is associated with a substantial rate of adverse events. We sought to design a machine learning (ML)-based model to predict the risk of in-hospital death and to perform a clustering of TTS patients to identify different risk profiles. METHODS AND RESULTS A ridge logistic regression-based ML model for predicting in-hospital death was developed on 3482 TTS patients from the International Takotsubo (InterTAK) Registry, randomly split in a train and an internal validation cohort (75% and 25% of the sample size, respectively) and evaluated in an external validation cohort (1037 patients). Thirty-one clinically relevant variables were included in the prediction model. Model performance represented the primary endpoint and was assessed according to area under the curve (AUC), sensitivity and specificity. As secondary endpoint, a K-medoids clustering algorithm was designed to stratify patients into phenotypic groups based on the 10 most relevant features emerging from the main model. The overall incidence of in-hospital death was 5.2%. The InterTAK-ML model showed an AUC of 0.89 (0.85-0.92), a sensitivity of 0.85 (0.78-0.95) and a specificity of 0.76 (0.74-0.79) in the internal validation cohort and an AUC of 0.82 (0.73-0.91), a sensitivity of 0.74 (0.61-0.87) and a specificity of 0.79 (0.77-0.81) in the external cohort for in-hospital death prediction. By exploiting the 10 variables showing the highest feature importance, TTS patients were clustered into six groups associated with different risks of in-hospital death (28.8% vs. 15.5% vs. 5.4% vs. 1.0.8% vs. 0.5%) which were consistent also in the external cohort. CONCLUSION A ML-based approach for the identification of TTS patients at risk of adverse short-term prognosis is feasible and effective. The InterTAK-ML model showed unprecedented discriminative capability for the prediction of in-hospital death.

Published
2023

23. 1149 MACHINE-LEARNING BASED PREDICTION OF IN-HOSPITAL DEATH FOR PATIENTS WITH TAKOTSUBO SYNDROME: THE INTERTAK-ML MODEL

Author

De Filippo, Ovidio, primary, Pancotti, Corrado, additional, Camman, Victoria Lucia, additional, Bianco, Matteo, additional, Gili, Sebastiano, additional, Di Mario, Carlo, additional, Luescher, Thomas, additional, Crea, Filippo, additional, Templin, Christian, additional, De Ferrari, Gaetano Maria, additional, and D´ascenzo, Fabrizio, additional

Published
2022
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24. 611 PLASMA EXOSOMES REFLECT MYOCARDIAL INJURY DETECTED BY CARDIAC MAGNETIC RESONANCE IN STEMI PATIENTS

Author

Baggiano, Andrea, primary, Zarà, Marta, additional, Banfi, Cristina, additional, Campodonico, Jeness, additional, Tedesco, Calogero, additional, Amadio, Patrizia, additional, Gili, Sebastiano, additional, Dona, Gianluca De, additional, Sandrini, Leonardo, additional, Maragna, Riccardo, additional, Marenzi, Giancarlo, additional, Pontone, Gianluca, additional, and Barbieri, Silvia Stella, additional

Published
2022
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26. Early Detection of Cardiovascular Risk Factors and Definition of Psychosocial Profile in Women Through a Systematic Approach: The Monzino Women Heart Center's Experience

Author

Gili, Sebastiano, Giuliani, Mattia, Santagostino Baldi, Giulia, Teruzzi, Giovanni, Pravettoni, Gabriella, Montorsi, Piero, and Trabattoni, Daniela

Subjects
anxiety and stress, cardiovascular prevention, gender medicine, psychological assessment, women heart disease, Settore MED/11 - Malattie dell'Apparato Cardiovascolare, Cardiology and Cardiovascular Medicine
Abstract

IntroductionCardiovascular (CV) disease is the leading mortality cause among women, yet an alarming misrepresentation of women in CV studies and a low awareness of the impact of CV among women still persist to date. The Monzino Women Heart Center has been established as a clinical and research program dedicated to primary prevention of CV disease in women.MethodsPatients aged between 35 and 60 years and with no history of CV disease underwent a comprehensive evaluation including a cardiologic outpatient visit with electrocardiogram, individual CV risk calculation, first-level cardiovascular examinations and a psychological assessment.ResultsA total of 635 women, with a mean age of 52.2 ± 6.4 participated to the project on a voluntary basis during the period January 2017–August 2021. Included patients had a high level of education (40.4% with a graduate or postgraduate university degree), the majority of them, in a stable couple and with children, were actively working. More than half of the patients performed physical activity on a regular basis. Prevalence of traditional CV risk factors were family history (70.2%), hypertension (46%), hypercholesterolemia (22%) and diabetes (14%). Early or premature menopause was reported by 17.7% of the patients, gestational hypertension and diabetes by 4.96 and 1.7%, respectively. Symptoms of depression were reported by 27%; nearly 36% of the participants rated high score of state anxiety and 41% of trait anxiety. Nearly 69% of the participants showed moderate-to-high perceived stress. The mean value of perceived general self-efficacy was moderate (mean = 28.78, SD = 4.69).ConclusionA CV prevention program dedicated to women can help identifying a considerable number of patients with risk factors for whom early interventions can help reducing the risk of developing CV disease. Psychological assessment might unmask depression or anxiety disorders, which might have a potential long-terme detrimental effect on CV health.

Published
2022

28. Gender-Associated Outcomes Following Percutaneous Coronary Intervention With a Third-Generation, Ultrathin-Strut Drug-Eluting Stent: A Real-World, Single-Center Experience

Author

Gili, Sebastiano, primary, Galli, Stefano, additional, Teruzzi, Giovanni, additional, Santagostino Baldi, Giulia, additional, Ravagnani, Paolo, additional, Fabbiocchi, Franco, additional, Bartorelli, Antonio, additional, Montorsi, Piero, additional, and Trabattoni, Daniela, additional

Published
2022
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30. 185 Diagnostic accuracy of dynamic stress myocardial CT perfusion as compared with invasive coronary physiology metrics in stented patients: preliminary results of the advantage II study

Author

Mushtaq, Saima, primary, Zanotto, Lorenza, additional, Conte, Edoardo, additional, Pontone, Gianluca, additional, Guglielmo, Marco, additional, Baggiano, Andrea, additional, Trabattoni, Daniela, additional, Gili, Sebastiano, additional, Galli, Stefano, additional, Troiano, Sarah, additional, Monizzi, Giovanni, additional, Melotti, Eleonora, additional, Lagrutta, Ludovico, additional, Randazzo, Angelo, additional, Bartorelli, Antonio, additional, and Andreini, Daniele, additional

Published
2021
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32. Clinical correlates and prognostic impact of neurologic disorders in Takotsubo syndrome.

Author

Cammann, Victoria L., Scheitz, Jan F., von Rennenberg, Regina, Jäncke, Lutz, Nolte, Christian H., Szawan, Konrad A., Stengl, Helena, Würdinger, Michael, Endres, Matthias, Templin, Christian, Ghadri, Jelena R., InterTAK Consortium, Citro, Rodolfo, Vecchione, Carmine, Bossone, Eduardo, Gili, Sebastiano, Neuhaus, Michael, Franke, Jennifer, Meder, Benjamin, and Jaguszewski, Miłosz

Subjects
ISCHEMIC stroke, INTRACRANIAL hemorrhage, NEUROLOGICAL disorders, HEART failure, VENTRICULAR ejection fraction
Abstract

Cardiac alterations are frequently observed after acute neurological disorders. Takotsubo syndrome (TTS) represents an acute heart failure syndrome and is increasingly recognized as part of the spectrum of cardiac complications observed after neurological disorders. A systematic investigation of TTS patients with neurological disorders has not been conducted yet. The aim of the study was to expand insights regarding neurological disease entities triggering TTS and to investigate the clinical profile and outcomes of TTS patients after primary neurological disorders. The International Takotsubo Registry is an observational multicenter collaborative effort of 45 centers in 14 countries (ClinicalTrials.gov, identifier NCT01947621). All patients in the registry fulfilled International Takotsubo Diagnostic Criteria. For the present study, patients were included if complete information on acute neurological disorders were available. 2402 patients in whom complete information on acute neurological status were available were analyzed. In 161 patients (6.7%) an acute neurological disorder was identified as the preceding triggering factor. The most common neurological disorders were seizures, intracranial hemorrhage, and ischemic stroke. Time from neurological symptoms to TTS diagnosis was ≤ 2 days in 87.3% of cases. TTS patients with neurological disorders were younger, had a lower female predominance, fewer cardiac symptoms, lower left ventricular ejection fraction, and higher levels of cardiac biomarkers. TTS patients with neurological disorders had a 3.2-fold increased odds of in-hospital mortality compared to TTS patients without neurological disorders. In this large-scale study, 1 out of 15 TTS patients had an acute neurological condition as the underlying triggering factor. Our data emphasize that a wide spectrum of neurological diseases ranging from benign to life-threatening encompass TTS. The high rates of adverse events highlight the need for clinical awareness. [ABSTRACT FROM AUTHOR]

Published
2021
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33. Balance isquémico-hemorrágico en pacientes diabéticos y no diabéticos tras un síndrome

Author

Domínguez-Rodríguez, Luis Manuel, Raposeiras-Roubín, Sergio, Abu-Assi, Emad, Cespón-Fernández, María, Melendo-Viu, María, D’ascenzo, Fabrizio, Kinnaird, Tim, Ariza-Solé, Albert, Manzano-Fernández, Sergio, Templin, Christian, Velicki, Lazar, Xanthopoulou, Ioanna, Cerrato, Enrico, Quadri, Giorgio, Rognoni, Andrea, Boccuzzi, Giacome, Montabone, Andrea, Taha, Salma, Durante, Alessandro, Gili, Sebastiano, Magnani, Giulia, Autelli, Michele, Grosso, Alberto, Flores-Blanco, Pedro, Garay, Alberto, Varbella, Ferdinando, Tommassini, Francesco, Gallo, Diego, Morbiducci, Umberto, Domínguez-Rodríguez, Alberto, Valdés, Mariano, Cequier, Ángel, Gaita, Fiorenzo, Alexopoulos, Dimitrios, and Íñiguez-Romo, Andrés

Abstract

Introduction and objectives: Bleeding and ischemic risk after acute coronary syndrome (ACS) is not uniform over time. Our objective was to determine the differences in post-ACS ischemic-hemorrhagic balance between diabetic and non-diabetic patients treated with dual antiplatelet therapy with prasugrel or ticagrelor.

Published
2022
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