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Optical coherence tomography angiography (OCTA), a functional extension of optical coherence tomography (OCT), is widely employed for high‐resolution imaging of microvascular networks. However, due to the relatively low scan rate of OCT, the artifacts caused by the involuntary bulk motion of tissues severely impact the visualization of microvascular networks. This study proposes a fast motion correction method based on image feature matching for OCT microvascular images. First, the rigid motion‐related mismatch between B‐scans is compensated through the image feature matching based on the improved oriented FAST and rotated BRIEF algorithm. Then, the axial motion within A‐scan lines in each B‐scan image is corrected according to the displacement deviation between the detected boundaries achieved by the Scharr operator in a non‐rigid transformation manner. Finally, an optimized intensity‐based Doppler variance algorithm is developed to enhance the robustness of the OCTA imaging. The experimental results demonstrate the effectiveness of the method. [ABSTRACT FROM AUTHOR]

Anisotropic elasticity measurements of the retina are essential for retinal disease diagnosis and function assessment. Optical coherence elastography (OCE) is a high-resolution imaging technique for mapping the elasticity distribution of tissues. However, previous OCE measurements quantified the tissue elasticity in a single direction, resulting in a biased estimation of the elastic properties. In this study, we propose an OCE method with acoustic radiation force (ARF) excitation to map the retinal anisotropic elasticity in the depth and lateral directions. The axial elasticity was analyzed using the natural frequency of free vibration, and the lateral elasticity was quantified using the elastic wave velocity. After evaluating the feasibility of the OCE method on the phantoms, the anisotropic elasticity of ex vivo porcine retinas was mapped. The results show that the OCE method with ARF excitation can assess the elasticity in orthogonal directions and provide a comprehensive understanding of the elasticity of the anisotropic tissues. [ABSTRACT FROM AUTHOR]

This article discusses a case of a 54-year-old Chinese woman with SAPHO syndrome, a rare auto-inflammatory disorder characterized by skin lesions and osteoarticular involvement, combined with optic neuritis. The patient experienced symptoms such as palmoplantar pustulosis, chest wall pain, and blurred vision in the right eye. After unsuccessful treatment with corticosteroids, the patient was switched to tofacitinib, which resulted in significant improvement in skin lesions, bone pain, and vision. The article suggests that tofacitinib may be an effective treatment option for ocular involvement in SAPHO syndrome when conventional treatments are ineffective. [Extracted from the article]

Introduction: Blau syndrome (BS) is a rare autoimmune disease. We report here an atypical case of BS. Case Presentation: We present a case of late-onset eye manifestations in a Chinese girl of 18 years old with sporadic BS, presenting with panuveitis. We performed comprehensive ocular examinations including fluorescein fundus angiography and indocyanine green angiography for her. The oral hormone plus local anti-inflammatory eye drops have well controlled the inflammation of her eyes. Conclusion: Our case highlights the necessity of systemic medical history inquiry for every eye discomfort. [ABSTRACT FROM AUTHOR]

Objective: Investigate the Correlation Between the Severity of Coronary Artery Disease and Retinal Artery Disease, and assess the Efficacy of Angiotensin-Converting Enzyme Inhibitors (ACEIs) Application., Methods: One hundred patients diagnosed with primary hypertension at our hospital were chosen for the study. All patients underwent dual-source 64-layer spiral CT coronary angiography and fundus photography examination. Based on the extent of coronary artery stenosis, the patients were divided into Group A, Group B, Group C, and Group D., Results: In comparison with patients in Group A, individuals in Groups B, C, and D exhibited a notable increase in the severity of retinal artery stenosis and arteriovenous crossing signs (P < .05). Furthermore, the severity of retinal artery stenosis and arteriovenous crossing signs demonstrated an incremental trend with the severity of coronary artery stenosis (P < .05). The arteriovenous crossing sign exhibited a sensitivity of 47.87%, the specificity of 89.21%, positive predictive value of 89.76%, and the negative predictive value of 46.53% for predicting coronary artery stenosis. After treatment, the blood pressure levels of the patients, both systolic (SBP) and diastolic blood pressure (DBP) levels significantly decreased compared to before treatment., Conclusion: A significant positive correlation was observed between the severity of coronary artery lesions and retinal artery lesions. Assessing alterations in retinal blood vessels in hypertensive patients can effectively indicate the extent of coronary artery stenosis indirectly. Concerning medication, the antihypertensive drug captopril demonstrated the potential to alleviate the severity of coronary artery and retinal artery lesions in hypertensive patients. However, specific treatment methods should be tailored to individual patient circumstances.

Rationale: Branch retinal artery occlusion (BRAO) is a rare complication of retinal arterial macroaneurysm (RAM), a low-incidence ocular disease., Patient Concerns: A 75-year-old woman presented with a chief complaint of blurred vision., Diagnoses: The patient for 4 days received a diagnosis of RAM combined with BRAO., Interventions: The patient was treated with two successive intravitreal conbercept injections., Outcomes: The patient's best-corrected visual acuity improved, and the RAM diminished., Lessons: Administration of conbercept injection might be an effective treatment for complex RAM with BRAO., Competing Interests: The authors have no funding and conflicts of interest to disclose., (Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.)