Search

Your search keyword '"Galossi, Elisa"' showing total 8 results
Start Over Author "Galossi, Elisa" Publication Year Range Last 3 years
8 results on '"Galossi, Elisa"'

3. Methodology and clinical utility of longitudinal UBA1 tracking in VEXAS syndrome.

Author

Gurnari, Carmelo, Galossi, Elisa, Lumia, Eleonora, Piciocchi, Alfonso, Divona, Mariadomenica, Casciani, Elisa, Romano, Francesca, Diral, Elisa, Tomelleri, Alessandro, Caroni, Federico, Vitale, Antonio, Bergonzi, Gregorio Maria, Condorelli, Annalisa, Battipaglia, Giorgia, Morsia, Erika, Crisà, Elena, Triggianese, Paola, Savi, Arianna, Cardamone, Chiara, and Dragani, Matteo

Subjects
*SOMATIC mutation, *POLYMERASE chain reaction, *SYMPTOMS, *MOLECULAR diagnosis, *AUTOIMMUNE diseases
Abstract

Summary Vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic (VEXAS) is a haemato‐inflammatory syndrome genetically defined by somatic mutations in the X‐linked UBA1 gene, typically Val/Thr/Leu substitutions at the Met41 hotspot. Clinical manifestations are heterogeneous and refractory to most haemato‐rheumatological treatments. To date, no guidelines exist for the management of VEXAS, and scarce is the evidence on methodology and clinical significance of longitudinal UBA1 clonal burden evaluation upon therapy. Here, we validated a method to quantify UBA1 clonal burden and explored its applicability in patients with VEXAS. Given the different treatment interactions, droplet digital polymerase chain reaction (ddPCR) may allow for informed therapeutic decisions and implementation of personalized strategies. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

6. Diagnostic capabilities, clinical features, and longitudinal UBA1 clonal dynamics of a nationwide VEXAS cohort.

Author

Gurnari, Carmelo, Pascale, Maria Rosaria, Vitale, Antonio, Diral, Elisa, Tomelleri, Alessandro, Galossi, Elisa, Falconi, Giulia, Bruno, Alessandro, Crisafulli, Francesca, Frassi, Micol, Cattaneo, Chiara, Bertoli, Diego, Bernardi, Massimo, Condorelli, Annalisa, Morsia, Erika, Poloni, Antonella, Crisà, Elena, Caravelli, Daniela, Triggianese, Paola, and Brussino, Luisa

Published
2024
Full Text
View/download PDF

7. New scenarios in Vacuoles, E1 enzyme, X linked, Autoinflammatory, Somatic (VEXAS) syndrome: Evolution from myelodysplastic syndrome to acute myeloid leukemia

Author

Battipaglia, Giorgia, primary, Vincenzi, Annamaria, additional, Falconi, Giulia, additional, Fiore, Alessia, additional, D'Agostino, Francesco, additional, Iannotta, Raffaella, additional, Grimaldi, Francesco, additional, Gurnari, Carmelo, additional, Galossi, Elisa, additional, Crisà, Elena, additional, Bonello, Francesca, additional, Scalia, Giulia, additional, Izzo, Barbara, additional, Voso, Maria Teresa, additional, and Pane, Fabrizio, additional

Published
2023
Full Text
View/download PDF

8. P778: A CARTOGRAPHY OF UBA1 GENE TESTING, EPIDEMIOLOGY AND CLINICAL‐GENOMIC CHARACTERISTICS: THE VEXAS ITALIAN EXPERIENCE.

Author

Gurnari, Carmelo, Rosaria Pascale, Maria, Vitale, Antonio, Diral, Elisa, Tomelleri, Alessandro, Galossi, Elisa, Falconi, Giulia, Bruno, Alessandro, Crisafulli, Francesca, Frassi, Micol, Cattaneo, Chiara, Bertoli, Diego, Bernardi, Massimo Stefano Luca, Condorelli, Annalisa, Morsia, Erika, Crisà, Elena, Triggianese, Paola, Borsellino, Beatrice, Brussino, Luisa, and Battipaglia, Giorgia

Published
2023
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results