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28 results on '"Gallego, Lucía"'

4. Intraoperative positive end-expiratory pressure and postoperative pulmonary complications: a patient-level meta-analysis of three randomised clinical trials

Author

Hemmes, Sabrine NT., Gama de Abreu, Marcelo, Severgnini, Paolo, Hollmann, Markus W., Binnekade, Jan M., Wrigge, Hermann, Canet, Jaume, Hiesmayr, Michael, Schmid, Werner, Tschernko, Edda, Jaber, Samir, Hedenstierna, Göran, Putensen, Christian, Pelosi, Paolo, Schultz, Marcus J., Marti, Agnes, Bacuzzi, Alessandro, Brodhun, Alexander, Molin, Alexandre, Merten, Alfred, Parera, Ana, Brunelli, Andrea, Cortegiani, Andrea, Güldner, Andreas, Reske, Andreas W., Gratarola, Angelo, Giarratano, Antonino, Bastin, Bea, Heyse, Bjorn, Mazul-Sunko, Branka, Amantea, Bruno, Barberis, Bruno, Uhlig, Christopher, Marín, Conrado Minguez, Celentano, Cristian, La Bella, Daniela, D’Antini, David, Velghe, David, Sulemanji, Demet, De Robertis, Edoardo, Hartmann, Eric, Montalto, Francesca, Tropea, Francesco, Mills, Gary H., Cinnella, Gilda, Della Rocca, Giorgio, Caggianelli, Girolamo, Pellerano, Giulia, Mollica, Giuseppina, Bugedo, Guillermo, Mulier, Jan-Paul, Vandenbrande, Jeroen, Geib, Johann, Yaqub, Jonathan, Florez, Jorge, Mayoral, Juan F., Sprung, Juraj, Van Limmen, Jurgen, Bos, Lieuwe DJ., de Baerdemaeker, Luc, Jamaer, Luc, Spagnolo, Luigi, Strys, Lydia, Gil, Manuel Granell, Vidal Melo, Marcos F., Unzueta, Maria Carmen, Moral, Maria Victoria, Ferner, Marion, Weiss, Martin, Vanoni, Massimo, Schaefer, Maximilian S., Prieto, Mercè, Grio, Michele, Spieth, Peter Markus, Simon, Philipp, Bodger, Phoebe, Sierra, Pilar, Laufenberg-Feldmann, Rita, Rusca, Roberta, Proietti, Rodolfo, Raineri, Santi Maurizio, Caroleo, Santo, Sabaté, Sergi, De Hert, Stefan, Pezzato, Stefano, Treschan, Tanja A., Goranovic, Tatjana, Koch, Thea, Bluth, Thomas, Kiss, Thomas, Perilli, Valter, Cegarra, Virginia, Ferrando, Carlos, Belda, Javier, Soro, Marina, Unzueta, Carmen, Suarez-Sipmann, Fernando, Librero, Julián, Llombart, Alicia, Rovira, Lucas, Granell, Manuel, Aldecoa, César, Diaz-Cambronero, Oscar, Balust, Jaume, Garutti, Ignacio, Gonzalez, Rafael, Gallego, Lucia, Garcia del Valle, Santiago, Redondo, Javier, Pestaña, David, Rodríguez, Aurelio, García, Javier, Matta, Manuel de la, Ibáñez, Maite, Barrios, Francisco, Hernández, Samuel, Torres, Vicente, Peiró, Salvador, Pozo, Natividad, Villena, Abigail, Carramiñana, Albert, Gallego-Casilda, Alberto, Duca, Alejandro, Alcón, Amalia, Miñana, Amanda, Asensio, Ana, Colás, Ana, Galve, Ana Isabel, Izquierdo, Ana, Jurado, Ana, Pérez, Ana María, Mugarra, Ana, Gutierrez, Andrea, De Miguel, Ángeles, Lozano, Angels, Katime, Antonio, Romero, Antonio, Garrigues, Beatriz, Ayas, Begoña, Arocas, Blanca, Delgado, Carlos, Fernández, Carmen, Romero, Carolina, Gallego, Clara, Garcés, Cristina, Lisbona, Cristina, Parrilla, Cristina, López-Herrera, Daniel, González, Domingo, Llamazares, Eduardo, Del Rio, Elena, Lozano, Elena, Pastor, Ernesto, Chamorro, Estefanía, Gracia, Estefanía, Sánchez, Ester, Romero, Esther, Díez, Fernando, Serralta, Ferran, Daviu, Francisco, Sandín, Francisco, Aguilar, Gerardo, Tusman, Gerardo, Azparren, Gonzalo, Martínez-Pallí, Graciela, Mazzinari, Guido, Benítez, Inmaculada, Hernandéz, Inmaculada, India, Inmaculada, León, Irene, Fuentes, Isabel, Ruiz, Isabel, Puig, Jaume, Román, Javie Ignacio, Acosta, Jesús, Rico-Feijoo, Jesús, Olmedo, Jonathan, Carbonell, Jose A., Alonso, Jose M., Pérez, Jose María, Marcos, Jose Miguel, Navarro, Jose, Valdivia, Jose, Carrizo, Juan, Piqueras, Laura, Soriano, Laura, Vaquero, Laura, Miguel, Lisset, Muñoz, Lorena, Valencia, Lucia, Olmedilla, Luis, Etulain, Mᵃ Justina, Tisner, Manuel, Barrio, María, Alonso, María Dolores, García, María, Hernández, María J., Alberola, María José, Parra, María, Argente, María Pilar, Vila, María, De Fez, Mario, Agilaga, Marta, Gine, Marta, Ayuso, Mercedes, García, Mercedes, Bejarano, Natalia, Peña, Natalia, Ojeda, Nazario, Martínez, Nilda, García, Nuria, Padrón, Oto, García, Pablo, Valls, Paola, Cruz, Patricia, Piñeiro, Patricia, Charco, Pedro, Anaya, Rafael, López, Ramiro, Rodríguez, Rayco, Martínez, Rocío, Pujol, Roger, Dosdá, Rosa, Lardies, Rosa, Díaz, Ruben, Villazala, Rubén, Zapatero, Sara, Cabrera, Sergio, Sánchez, Sergio, Martin, Silvia, Diaz, Suzana, Franco, Tania, Moreno, Tania, Socorro, Tania, Gilabert, Vicente, Balandrón, Victor, Moral, Victoria, Cegarra, Virgina, Varón, Viviana, Abelha, Fernando, Abitağaoğlu, Sühayla, Achilles, Marc, Adebesin, Afeez, Adriaensens, Ine, Ahene, Charles, Akbar, Fatima, Al Harbi, Mohammed, Al Khoury al Kallab, Rita, Albanel, Xavier, Aldenkortt, Florence, Saleh Alfouzan, Rawan Abdullah, Alruqaie, Reef, Altermatt, Fernando, Luís de Castro Araujo, Bruno, Arbesú, Genaro, Artsi, Hanna, Aurilio, Caterina, Ayanoglu, Omer Hilmi, Baig, Harris, Baird, Yolanda, Balonov, Konstantin, Banks, Samantha, Bao, Xiaodong, Baumgartner, Mélanie, Tortosa, Isabel Belda, Bergamaschi, Alice, Bergmann, Lars, Bigatello, Luca, Pérez, Elena Biosca, Birr, Katja, Bojaxhi, Elird, Bonenti, Chiara, Bonney, Iwona, Bos, Elke M.E., Bowman, Sara, Braz, Leandro Gobbo, Brugnoni, Elisa, Brull, Sorin J., Brunetti, Iole, Bruni, Andrea, Buenvenida, Shonie L., Busch, Cornelius Johannes, Camerini, Giovanni, Capatti, Beatrice, Carmona, Javiera, Carungcong, Jaime, Carvalho, Marta, Cattan, Anat, Cavaleiro, Carla, Chiumello, Davide, Ciardo, Stefano, Coburn, Mark, Colella, Umberto, Contreras, Victor, Dincer, Pelin Corman, Cotter, Elizabeth, Crovetto, Marcia, Darrah, William, Davies, Simon, Del Cojo Peces, Enrique, Delphin, Ellise, Diaper, John, Junior, Paulo do Nascimento, Donatiello, Valerio, Dong, Jing, Dourado, Maria do Socorro, Dullenkopf, Alexander, Ebner, Felix, Elgendy, Hamed, Ellenberger, Christoph, Arı, Dilek Erdoğan, Ermert, Thomas, Farah, Fadi, Fernandez-Bustamante, Ana, Ferreira, Cristina, Fiore, Marco, Fonte, Ana, Palahí, Christina Fortià, Galimberti, Andrea, Garofano, Najia, Giaccari, Luca Gregorio, Gilsanz, Fernando, Girrbach, Felix, Gobbi, Luca, Godfried, Marc Bernard, Goettel, Nicolai, Goldstein, Peter A., Goren, Or, Gorlin, Andrew, Graterol, Juan, Guyon, Pierre, Haire, Kevin, Harou, Philippe, Helf, Antonia, Hemmes, Sabrine N.T., Hempel, Gunther, Hernández Cádiz, María José, Heyse, Björn, Huercio, Ivan, Ilievska, Jasmina, Jakus, Lien, Jeganath, Vijay, Jelting, Yvonne, Jung, Minoa, Kabon, Barbara, Kacha, Aalok, Ilić, Maja Karaman, Karuppiah, Arunthevaraja, Kavas, Ayse Duygu, Barcelos, Gleicy Keli, Kellogg, Todd A., Kemper, Johann, Kerbrat, Romain, Khodr, Suraya, Kienbaum, Peter, Kir, Bunyamin, Kivrak, Selin, Klarić, Vlasta, Köksal, Ceren, Kowark, Ana, Kranke, Peter, Kuvaki, Bahar, Kuzmanovska, Biljana, Laffey, John, Lange, Mirko, Freitas de Lemos, Marília, Licker, Marc-Joseph, López-Baamonde, Manuel, López-Hernández, Antonio, Lopez-Martinez, Mercedes, Luise, Stéphane, MacGregor, Mark, Magalhães, Danielle, Maillard, Julien, Malerbi, Patrizia, Manimekalai, Natesan, Margarson, Michael, Markstaller, Klaus, Martin, Archer K., Martin, David P., Martin, Yvette N., Martínez-Ocon, Julia, Martin-Loeches, Ignacio, Maseda, Emilio, Matot, Idit, McAuliffe, Niamh, McKenzie, Travis J., Medina, Paulina, Meersch, Melanie, Menzen, Angelika, Mertens, Els, Meurer, Bernd, Meyer-Treschan, Tanja, Miao, Changhong, Micalizzi, Camilla, Milić, Morena, Pinheiro Módolo, Norma Sueli, Moine, Pierre, Mölders, Patrick, Montero-Feijoo, Ana, Moret, Enrique, Muller, Markus K., Murphy, Zoe, Nalwaya, Pramod, Naumovski, Filip, Navalesi, Paolo, Navarro e Lima, Lais Helena, Adam, Višnja Nesek, Neumann, Claudia, Newell, Christopher, Nisnevitch, Zoulfira, Nizamuddin, Junaid, Novazzi, Cecilia, O'Connor, Michael, Oprea, Günther, Sungur, Mukadder Orhan, Özbilgin, Şule, Pace, Maria Caterina, Pacheco, Marcos, Packianathaswamy, Balaji, Gonzalez, Estefania Palma, Papaspyros, Fotios, Paredes, Sebastián, Passavanti, Maria Beatrice, Pedemonte, Juan Cristobal, Peremin, Sanja, Philipsenburg, Christoph, Pinho, Daniela, Pinho, Silvia, Posthuma, Linda M., Pota, Vincenzo, Preckel, Benedikt, Priani, Paolo, Rached, Mohamed Aymen, Radoeshki, Aleksandar, Ragazzi, Riccardo, Rajamanickam, Tamilselvan, Rajamohan, Arthi, Ramakrishna, Harish, Rangarajan, Desikan, Reiterer, Christian, Renew, J. Ross, Reynaud, Thomas, Rhys, Rhidian, Rivas, Eva, Robitzky, Luisa, Rossaint, Rolf, Rubulotta, Francesca, Machado, Humberto S., Nunes, Catarina S., Sabbatini, Giovanni, Samuels, Jon D., Sanahuja, Josep Martí, Sansone, Pasquale, Santos, Alice, Sayedalahl, Mohamed, Scharffenberg, Martin, Schiffer, Eduardo, Schliewe, Nadja, Schorer, Raoul, Schumann, Roman, Selmo, Gabriele, Sendra, Mar, Senturk, Mert, Shaw, Kate, Shosholcheva, Mirjana, Sibai, Abdulrazak, Simonassi, Francesca, Sinno, Claudia, Sivrikoz, Nukhet, Skandalou, Vasiliki, Smith, Neil, Soares, Maria, Artiles, Tania Socorro, Castro, Diogo Sousa, Sousa, Miguel, Spadaro, Savino, Stamatakis, Emmanouil, Steiner, Luzius A., Stevenazzi, Andrea, Suarez-de-la-Rica, Alejandro, Suppan, Mélanie, Teichmann, Robert, Tena Guerrero, José Maria, Thiel, Bram, Tolós, Raquel, Altun, Gulbin Tore, Tucci, Michelle, Turnbull, Zachary A., Turudić, Žana, Unterberg, Matthias, Van Nieuwenhove, Yves, Van Waesberghe, Julia, Vidal Melo, Marcos Francisco, Vitković, Bibiana, Vivona, Luigi, Vizcaychipi, Marcela, Volta, Carlo Alberto, Weber, Anne, Weingarten, Toby N., Wittenstein, Jakob, Wyffels, Piet, Yagüe, Julio, Yates, David, Yavru, Ayşen, Zac, Lilach, Zhong, Jing, Campos, Niklas S., Librero, Julian, Ball, Lorenzo, and Serpa Neto, A.

Published
2022
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6. Genomic Surveillance Uncovers a 10-Year Persistence of an OXA-24/40 Acinetobacter baumannii Clone in a Tertiary Hospital in Northern Spain

Author

Aranzamendi, Maitane, primary, Xanthopoulou, Kyriaki, additional, Sánchez-Urtaza, Sandra, additional, Burgwinkel, Tessa, additional, Arazo del Pino, Rocío, additional, Lucaßen, Kai, additional, Pérez-Vázquez, M., additional, Oteo-Iglesias, Jesús, additional, Sota, Mercedes, additional, Marimón, Jose María, additional, Seifert, Harald, additional, Higgins, Paul G., additional, and Gallego, Lucía, additional

Published
2024
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8. Carpyridines as Versatile Platforms for Shape-Assisted Self-Assembly and for Energy Transfer

Author

Gallego, Lucía and Gallego, Lucía

Abstract

Shape, and particularly, curvature is a powerful and underexplored tool in chemical systems that will be exploited in this Thesis through different projects. To this aim, this Thesis is structured in 4 different Chapters that revolve around the same core structure: a saddle-shaped nitrogen containing macrocycle that we have termed carpyridine as a result of its constituents: carbazole and pyridine. Chapter 1 shows the influence that the saddle shape has on the self-assembling capabilities of this macrocycle when substituted with alkyl chains on the carbazoles. The restriction of the translational and rotational movements within a stack of carpyridines has resulted in two-dimensional supramolecular polymers in the form of sheets with micrometer lengths and molecular thicknesses in the absence of strong directional interactions. The elucidation of the composition of these nanosheets resulted in loosely packed columns driven by pi–pi interactions between monomers that associate laterally through Van der Waals interactions to form the two-dimensional surface. We term this process Shape-Assisted Self-Assembly. Chapter 2 contains the findings from further alkyl substitution on the para positions of the pyridines as a follow-up to Chapter 1. This results in tighter column formation and avoidance of lateral association between columns. A one-dimensional supramolecular polymer is then obtained, allowing for characterization of this new assembly both on surface and in solution. The self-assembly mechanism has been elucidated with different spectroscopic techniques, resulting in thermodynamic parameters comparable to those obtained from hydrogen-bonded systems. Chapter 3 entails the efforts in substituting one of the para positions of the pyridines with a hydrophilic sidechain, namely a triethyleneglycol. This affords an amphiphilic compound for which the self-assembly behavior can be studied in aqueous mixtures. Different morphologies like micelles or vesicles can be formed b

Published
2024

11. Saddles as rotational locks within shape-assisted self-assembled nanosheets

Author

Woods, Joseph F., primary, Gallego, Lucía, additional, Maisch, Amira, additional, Renggli, Dominik, additional, Cuocci, Corrado, additional, Blacque, Olivier, additional, Steinfeld, Gunther, additional, Kaech, Andres, additional, Spingler, Bernhard, additional, Vargas Jentzsch, Andreas, additional, and Rickhaus, Michel, additional

Published
2023
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12. Saddles as rotational locks within shape-assisted self-assembled nanosheets

Author

Woods, Joseph F; https://orcid.org/0000-0001-8661-4844, Gallego, Lucía; https://orcid.org/0000-0001-7639-9976, Maisch, Amira, Renggli, Dominik, Cuocci, Corrado, Blacque, Olivier; https://orcid.org/0000-0001-9857-4042, Steinfeld, Gunther, Kaech, Andres; https://orcid.org/0000-0002-7035-9858, Spingler, Bernhard; https://orcid.org/0000-0003-3402-2016, Vargas Jentzsch, Andreas; https://orcid.org/0000-0003-1386-3174, Rickhaus, Michel; https://orcid.org/0000-0002-6107-2310, Woods, Joseph F; https://orcid.org/0000-0001-8661-4844, Gallego, Lucía; https://orcid.org/0000-0001-7639-9976, Maisch, Amira, Renggli, Dominik, Cuocci, Corrado, Blacque, Olivier; https://orcid.org/0000-0001-9857-4042, Steinfeld, Gunther, Kaech, Andres; https://orcid.org/0000-0002-7035-9858, Spingler, Bernhard; https://orcid.org/0000-0003-3402-2016, Vargas Jentzsch, Andreas; https://orcid.org/0000-0003-1386-3174, and Rickhaus, Michel; https://orcid.org/0000-0002-6107-2310

Abstract

Two-dimensional (2D) materials are a key target for many applications in the modern day. Self-assembly is one approach that can bring us closer to this goal, which usually relies upon strong, directional interactions instead of covalent bonds. Control over less directional forces is more challenging and usually does not result in as well-defined materials. Explicitly incorporating topography into the design as a guiding effect to enhance the interacting forces can help to form highly ordered structures. Herein, we show the process of shape-assisted self-assembly to be consistent across a range of derivatives that highlights the restriction of rotational motion and is verified using a diverse combination of solid state analyses. A molecular curvature governed angle distribution nurtures monomers into loose columns that then arrange to form 2D structures with long-range order observed in both crystalline and soft materials. These features strengthen the idea that shape becomes an important design principle leading towards precise molecular self-assembly and the inception of new materials.

Published
2023

13. Manejo de la mola hidatiforme. Reporte de un caso

Author

Cuaresma-González, María, primary, Barrero-Real, Laura, additional, García-García, Elena, additional, Pérez-Gallego, Lucía, additional, Gobernado-Tejedor, Julio Alberto, additional, and Ibáñez-Nieto, Marta, additional

Published
2023
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16. Rebound in sexually transmitted infections after the COVID-19 pandemic.

Author

Soriano, Vicente, Blasco-Fontecilla, Hilario, Gallego, Lucía, Fernández-Montero, José V., de Mendoza, Carmen, and Barreiro, Pablo

Subjects
SEXUALLY transmitted diseases, RESPIRATORY diseases, COVID-19 pandemic, HUMAN ecology, VIRAL hepatitis
Abstract

Sexually transmitted infections (STIs) have become the second in the global rating of infectious diseases after respiratory infections. Globally, over 1 million, new STI is diagnosed every day. Although four conditions are the most representative and of obligatory declaration (gonorrhea, syphilis, chlamydia, and human immunodeficiency virus [HIV]), there are many other prevalent STI, including trichomona, herpes simplex, papillomavirus, and viral hepatitis. Herein, we perform a narrative and retrospective review, analyzing information from public databases from distinct Spanish government institutions. STI significantly declined in Spain during 2020 as a result of lockdown and social isolation measures dictated in response to the COVID-19 pandemic. After releasing restrictions, a major STI rebound occurred in 2021. Increases were 49% for gonorrhea, 45% for HIV, 39% for chlamydia, and 32% for syphilis. Based on nationwide statistics, we build a narrative review of the recent STI surge after COVID-19. In summary, we propose a holistic approach to confront the current re-emergence of STI. On one hand, new innovative medical advances must be implemented, including new rapid tests, novel vaccines, pre-exposure prophylaxis beyond HIV, and long-acting antivirals. On the other hand, information to citizens needs to be reformulated with interventions aimed to build a healthier society, alike it has been undertaken with tobacco, alcohol, diet, and lifestyle. STI determines important sexual, reproductive, and maternal-child health consequences. To promote human well-being or flourishing, the education of adolescents and young adults should be aligned with human ecology. Therefore, it is urgent to address new approaches in sexual health that represent a clear benefit for individual persons and society. In this way, favoring a cultural evolution aimed to delay the age of first sexual intercourse and the avoidance of multiple sex partners should be prioritized. [ABSTRACT FROM AUTHOR]

Published
2023
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18. Recent Concepts for Supramolecular 2D Materials

Author

Gallego, Lucía; https://orcid.org/0000-0001-7639-9976, Woods, Joseph F; https://orcid.org/0000-0001-8661-4844, Rickhaus, Michel; https://orcid.org/0000-0002-6107-2310, Gallego, Lucía; https://orcid.org/0000-0001-7639-9976, Woods, Joseph F; https://orcid.org/0000-0001-8661-4844, and Rickhaus, Michel; https://orcid.org/0000-0002-6107-2310

Abstract

Bottom-up approaches are one strategy geared towards designing novel two-dimensional materials. Supramolecular polymerization has proven to be an effective way of obtaining these architectures due to the increasing control and tunability offered by different functional groups, which are not afforded by conventional polymerization. In this short review, we highlight examples of supramolecular assemblies held together by well-known non-covalent interactions, as well as new approaches that are becoming more relevant in recent years.

Published
2022

19. Shape-assisted self-assembly

Author

Woods, Joseph F; https://orcid.org/0000-0001-8661-4844, Gallego, Lucía; https://orcid.org/0000-0001-7639-9976, Pfister, Pauline, Maaloum, Mounir, Vargas Jentzsch, Andreas; https://orcid.org/0000-0003-1386-3174, Rickhaus, Michel; https://orcid.org/0000-0002-6107-2310, Woods, Joseph F; https://orcid.org/0000-0001-8661-4844, Gallego, Lucía; https://orcid.org/0000-0001-7639-9976, Pfister, Pauline, Maaloum, Mounir, Vargas Jentzsch, Andreas; https://orcid.org/0000-0003-1386-3174, and Rickhaus, Michel; https://orcid.org/0000-0002-6107-2310

Abstract

Self-assembly and molecular recognition are critical processes both in life and material sciences. They usually depend on strong, directional non-covalent interactions to gain specificity and to make long-range organization possible. Most supramolecular constructs are also at least partially governed by topography, whose role is hard to disentangle. This makes it nearly impossible to discern the potential of shape and motion in the creation of complexity. Here, we demonstrate that long-range order in supramolecular constructs can be assisted by the topography of the individual units even in the absence of highly directional interactions. Molecular units of remarkable simplicity self-assemble in solution to give single-molecule thin two-dimensional supramolecular polymers of defined boundaries. This dramatic example spotlights the critical function that topography can have in molecular assembly and paves the path to rationally designed systems of increasing sophistication.

Published
2022

20. Recent Concepts for Supramolecular 2D Materials

Author

Gallego, Lucía, Woods, Joseph F, Rickhaus, Michel, and University of Zurich

Subjects
10120 Department of Chemistry, 540 Chemistry, Microbiology
Abstract

Bottom-up approaches are one strategy geared towards designing novel two-dimensional (2D) materials. Supramolecular polymerization has proven to be an effective way of obtaining these architectures due to the increasing control and tuneability offered by different functional groups, which are not afforded by conventional polymerization. In this short review, we highlight examples of supramolecular assemblies held together by well-known non-covalent interactions, as well as new approaches that are becoming more relevant in recent years.

Published
2022
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21. Shape-Assisted Self-Assembly

Author

Woods, Joseph F., primary, Gallego, Lucía, additional, Pfister, Pauline, additional, Maaloum, Mounir, additional, Vargas Jentzsch, Andreas, additional, and Rickhaus, Michel, additional

Published
2022
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27. Shape-Assisted Self-Assembly of Hexa-Substituted Carpyridines into 1D Supramolecular Polymers.

Author

Gallego L, Woods JF, Butti R, Szwedziak P, Vargas Jentzsch A, and Rickhaus M

Abstract

The extent of the influence that molecular curvature plays on the self-assembly of supramolecular polymers remains an open question in the field. We began addressing this fundamental question with the introduction of "carpyridines", which are saddle-shaped monomers that can associate with one another through π-π interactions and in which the rotational and translational movements are restricted. The topography displayed by the monomers led, previously, to the assembly of highly ordered 2D materials even in the absence of strong directional interactions such as hydrogen bonding. Here, we introduce a simple strategy to gain control over the dimensionality of the formed structures yielding classical unidimensional polymers. These have been characterized using well-established protocols allowing us to determine and confirm the self-assembly mechanism of both fibers and sheets. The calculated interaction energies are significantly higher than expected for flexible self-assembling units lacking classical "strong" non-covalent interactions. The versatility of this supramolecular unit to assemble into either supramolecular fibers or 2D sheets with strong association energies highlights remarkably well the potential and importance of molecular shape for the design of supramolecular materials and the applications thereof., (© 2024 The Authors. Angewandte Chemie International Edition published by Wiley-VCH GmbH.)

Published
2024
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28. [Euthanasia and assisted suicide in people with mental disorders].

Author

Gallego L, Barreiro Y Manuel de Santiago P, and de Santiago M

Subjects
Humans, Netherlands, Quality of Life, Euthanasia, Mental Disorders, Suicide, Assisted
Abstract

Until 2020, only Belgium, Luxembourg, Switzerland, and the Netherlands admitted, under differentiated legal coverage, requests for euthanasia and / or assisted suicide in patients with non-terminal illnesses, and for reasons of intractable and unbearable suffering. Since March 2021 this is also possible in Spain. The objective of this work is to review the existing studies and characteristics of the practice of euthanasia and assisted suicide (ESA) in people with mental disorders (TM) and / or dementia (D) and see if the legal requirements essential in ESA applications in these patients are to be met. The hypothesis is that compliance with these requirements is especially difficult in patients with TM-D, either because of the characteristics of the disease itself, or because of the recognized legal security failures. Likewise, there may be sources of fraud not actually prosecuted by the State, either due to the complicity of society and / or due to the necessary cooperation of Medicine. As a result of this review, we raise criticaethical-deontological considerations about the approval of ESA for patients with TM-D, and its errors and consequences, to the reflection of the readers. We propose as an alternative to ESA the so-called ″palliative psychiatry″, which aims at improving the quality of life of patients and their families by facing the problems associated with severe persistent mental illness -potentially fatal- through the prevention and relief of suffering.

Published
2022
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