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Your search keyword '"Fuller, Patrick M."' showing total 9 results
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1. Sleep mechanisms

Author

Fuller, Patrick M., primary, Zee, Phyllis C., additional, Buxton, Orfeu M., additional, and Avidan, Alon Y., additional

Published
2024
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2. Contributors

Author

Abbott, Sabra M., primary, Abe, Takashi, additional, Ali, Imran I., additional, Arnedt, J. Todd, additional, Avidan, Alon Y., additional, Bartsch, Ronny P., additional, Benca, Ruth M., additional, Buxton, Orfeu M., additional, Chang, Anne-Marie, additional, Chervin, Ronald D., additional, Collop, Nancy, additional, Corrigan, Jennifer, additional, Dinges, David F., additional, During, Emmanuel H., additional, Dutt, Mohan, additional, Eckert, Danny J., additional, Edinger, Jack D., additional, Eldridge-Smith, E. Devon, additional, Formentin, Chiara, additional, Fuller, Patrick M., additional, Geer, Jacqueline, additional, Goldstein, Cathy, additional, Hanly, Patrick J., additional, Harper, Ronald M., additional, Hirshkowitz, Max, additional, Howell, Michael J., additional, Ip, Mary S.M., additional, Irfan, Muna, additional, Ivanov, Plamen Ch., additional, Javaheri, Shahrokh, additional, Javaheri, Sogol, additional, Jones, Christopher W., additional, Ju, Yo-El S., additional, Kaizi-Lutu, Marc, additional, Kapas, Levente, additional, Kryger, Meir H., additional, Kutscher, Scott J., additional, Lee, Won Y., additional, Liu, Peter Y., additional, Lui, Macy M.S., additional, Lussier, Bethany L., additional, Malhotra, Atul, additional, Malhotra, Raman K., additional, McCall, Catherine A., additional, McCall, William V., additional, Mendelson, Wallace, additional, Montagnese, Sara, additional, Parmeggiani, Pier Luigi, additional, Prather, Aric A., additional, Reid, Kathryn J., additional, Roth, Thomas, additional, Schneider, Logan Douglas, additional, Shapiro, Colin M., additional, Sharafkhaneh, Amir, additional, Sheikh, Ajaz A., additional, Sheldon, Stephen H., additional, Sherman, Deena, additional, Siegel, Jerome M., additional, Spaeth, Andrea M., additional, Stickgold, Robert, additional, Summa, Keith C., additional, Swanson, Leslie, additional, Szentirmai, Éva, additional, Tobias, Lauren, additional, Turek, Fred W., additional, Turnbull, Christopher D., additional, Vaughn, Bradley V., additional, Verrier, Richard L., additional, Wamsley, Erin J., additional, West, Sophie D., additional, Whibley, Daniel, additional, Winkelman, John W., additional, Wojeck, Brian S., additional, Won, Christine H.J., additional, Yao, Steven, additional, Yuen, Kin M., additional, and Zee, Phyllis C., additional

Published
2024
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3. GABAergic signalling in the suprachiasmatic nucleus is required for coherent circadian rhythmicity.

Author

Klett, Nathan, Gompf, Heinrich S., Allen, Charles N., Cravetchi, Olga, Hablitz, Lauren M., Gunesch, Ali N., Irwin, Robert P., Todd, William D., Saper, Clifford B., and Fuller, Patrick M.

Subjects
GABA transporters, GABA receptors, NEURAL transmission, GABA, CIRCADIAN rhythms, SUPRACHIASMATIC nucleus, NEUROTRANSMITTER receptors
Abstract

The suprachiasmatic nucleus is the circadian pacemaker of the mammalian brain. Suprachiasmatic nucleus neurons display synchronization of their firing frequency on a circadian timescale, which is required for the pacemaker function of the suprachiasmatic nucleus. However, the mechanisms by which suprachiasmatic nucleus neurons remain synchronized in vivo are poorly understood, although synaptic communication is considered indispensable. Suprachiasmatic nucleus neurons contain the neurotransmitter GABA and express GABA receptors. This has inspired the hypothesis that GABA signalling may play a central role in network synchronization, although this remains untested in vivo. Here, using local genetic deletion, we show that disruption of GABA synaptic transmission within the suprachiasmatic nucleus of adult mice results in the eventual deterioration of physiological and behavioural rhythmicity in vivo and concomitant cellular desynchrony in vitro. These findings suggest that intercellular GABA signalling is essential for behavioural rhythmicity and cellular synchrony of the suprachiasmatic nucleus neural network. [ABSTRACT FROM AUTHOR]

Published
2024
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4. Orexin neurons inhibit sleep to promote arousal

Author

De Luca, Roberto, Nardone, Stefano, Grace, Kevin P., Venner, Anne, Cristofolini, Michela, Bandaru, Sathyajit S., Sohn, Lauren T., Kong, Dong, Mochizuki, Takatoshi, Viberti, Bianca, Zhu, Lin, Zito, Antonino, Scammell, Thomas E., Saper, Clifford B., Lowell, Bradford B., Fuller, Patrick M., and Arrigoni, Elda

Published
2022
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6. Beyond the symptom : the biology of fatigue

Author

Raizen, David M., Mullington, Janet, Anaclet, Christelle, Clarke, Gerard, Critchley, Hugo, Dantzer, Robert, Davis, Ronald, Drew, Kelly L., Fessel, Josh, Fuller, Patrick M., Gibson, Erin M., Harrington, Mary, Lipkin, W. Ian, Klerman, Elizabeth B., Klimas, Nancy, Komaroff, Anthony L., Koroshetz, Walter, Krupp, Lauren, Kuppuswamy, Anna, Lasselin, Julie, Lewis, Laura D., Magistretti, Pierre J., Matos, Heidi Y., Miaskowski, Christine, Miller, Andrew H., Nath, Avindra, Nedergaard, Maiken, Opp, Mark R., Ritchie, Marylyn D., Rogulja, Dragana, Rolls, Asya, Salamone, John D., Saper, Clifford, Whittemore, Vicky, Wylie, Glenn, Younger, Jarred, Zee, Phyllis C., Heller, H. Craig, Raizen, David M., Mullington, Janet, Anaclet, Christelle, Clarke, Gerard, Critchley, Hugo, Dantzer, Robert, Davis, Ronald, Drew, Kelly L., Fessel, Josh, Fuller, Patrick M., Gibson, Erin M., Harrington, Mary, Lipkin, W. Ian, Klerman, Elizabeth B., Klimas, Nancy, Komaroff, Anthony L., Koroshetz, Walter, Krupp, Lauren, Kuppuswamy, Anna, Lasselin, Julie, Lewis, Laura D., Magistretti, Pierre J., Matos, Heidi Y., Miaskowski, Christine, Miller, Andrew H., Nath, Avindra, Nedergaard, Maiken, Opp, Mark R., Ritchie, Marylyn D., Rogulja, Dragana, Rolls, Asya, Salamone, John D., Saper, Clifford, Whittemore, Vicky, Wylie, Glenn, Younger, Jarred, Zee, Phyllis C., and Heller, H. Craig

Abstract

A workshop titled “Beyond the Symptom: The Biology of Fatigue” was held virtually September 27–28, 2021. It was jointly organized by the Sleep Research Society and the Neurobiology of Fatigue Working Group of the NIH Blueprint Neuroscience Research Program. For access to the presentations and video recordings, see: https://neuroscienceblueprint.nih.gov/about/event/beyond-symptom-biology-fatigue. The goals of this workshop were to bring together clinicians and scientists who use a variety of research approaches to understand fatigue in multiple conditions and to identify key gaps in our understanding of the biology of fatigue. This workshop summary distills key issues discussed in this workshop and provides a list of promising directions for future research on this topic. We do not attempt to provide a comprehensive review of the state of our understanding of fatigue, nor to provide a comprehensive reprise of the many excellent presentations. Rather, our goal is to highlight key advances and to focus on questions and future approaches to answering them.

Published
2023
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7. Beyond the symptom: the biology of fatigue

Author

Raizen, David M, primary, Mullington, Janet, additional, Anaclet, Christelle, additional, Clarke, Gerard, additional, Critchley, Hugo, additional, Dantzer, Robert, additional, Davis, Ronald, additional, Drew, Kelly L, additional, Fessel, Josh, additional, Fuller, Patrick M, additional, Gibson, Erin M, additional, Harrington, Mary, additional, Ian Lipkin, W, additional, Klerman, Elizabeth B, additional, Klimas, Nancy, additional, Komaroff, Anthony L, additional, Koroshetz, Walter, additional, Krupp, Lauren, additional, Kuppuswamy, Anna, additional, Lasselin, Julie, additional, Lewis, Laura D, additional, Magistretti, Pierre J, additional, Matos, Heidi Y, additional, Miaskowski, Christine, additional, Miller, Andrew H, additional, Nath, Avindra, additional, Nedergaard, Maiken, additional, Opp, Mark R, additional, Ritchie, Marylyn D, additional, Rogulja, Dragana, additional, Rolls, Asya, additional, Salamone, John D, additional, Saper, Clifford, additional, Whittemore, Vicky, additional, Wylie, Glenn, additional, Younger, Jarred, additional, Zee, Phyllis C, additional, and Craig Heller, H, additional

Published
2023
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