Search

Your search keyword '"Fischer, Mary"' showing total 39 results
Start Over Author "Fischer, Mary" Publication Year Range Last 3 years
39 results on '"Fischer, Mary"'

4. No Longer Chasing Our Tails: The Evolution of Clinical Informatics Standardization

Author

Wright, Jennifer, Arnold, Lucy, Barnes, Julie, Fischer, Mary Hughes, Ganger, Baley, Johnson, Lisa, Lord, Amanda, Nitterhouse, Brooke, and Williams, Teresa

Subjects
Health care reform, Usability testing, Medical colleges, Health care industry, Medical University of South Carolina
Abstract

Medical University of South Carolina Clinical Informatics standardized the practice of creating templates, workflows, and design documents to bridge the gap among people, process, and technology. Standardization of processes and innovative strategies benefits the enterprise and improves health care. Keywords: clinical informatics, design, standardization, usability, rounding, communication, maturity model, data, At its foundation, clinical informatics (CI) is a role merging clinical and technical language to improve clinical outcomes while enhancing clinical workflows. Clinical informaticists apply clinical knowledge and wisdom to [...]

Published
2023

7. Shelter from the storm: The growing threats from climate change to housing in the United States.

Author

Fischer, Mary J.

Subjects
HOUSING policy, HOUSING, CLIMATE change, HOUSING stability, HOUSING discrimination
Abstract

Climate change and its related impacts are fast becoming the dominant force in the housing market. The fundamental role that housing plays in people's lives makes these effects particularly pernicious, often impacting employment, school attendance, undermining physical and mental health, disrupting social networks, and contributing to food insecurity. The complexity of addressing these issues is compounded by the cyclical and reciprocal relationships among these factors, with housing inequalities frequently lying at the core and climate change impacts percolating throughout. I introduce the framework of acute, secondary, and pre‐emptive/reactive impacts to help understand these mechanisms. To understand and contextualize these connections, I provide a brief overview racial segregation in the United States and related inequalities that place some individuals, groups, and communities at greater risk. Other key sources of housing instability in the United States that are often closely related to housing segregation include lack of affordable housing, growing income inequality, housing discrimination, evictions, and foreclosures, all of which contribute to unequal housing outcomes. These factors are explored using the temporal framework to discuss their connection to climate change, which is in and of itself a major force of housing instability. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

8. Host JAK-STAT activity is a target of parasitoid wasp virulence strategies.

Author

Brantley, Susanna E., Stouthamer, Corinne M., Kr, Pooja, Fischer, Mary L., Hill, Joshua, Schlenke, Todd A., and Mortimer, Nathan T.

Subjects
JAK-STAT pathway, PARASITOIDS, WASPS, DROSOPHILA melanogaster, CELLULAR signal transduction, GAIN-of-function mutations
Abstract

Innate immune responses that allow hosts to survive infection depend on the action of multiple conserved signaling pathways. Pathogens and parasites in turn have evolved virulence factors to target these immune signaling pathways in an attempt to overcome host immunity. Consequently, the interactions between host immune molecules and pathogen virulence factors play an important role in determining the outcome of an infection. The immune responses of Drosophila melanogaster provide a valuable model to understand immune signaling and host-pathogen interactions. Flies are commonly infected by parasitoid wasps and mount a coordinated cellular immune response following infection. This response is characterized by the production of specialized blood cells called lamellocytes that form a tight capsule around wasp eggs in the host hemocoel. The conserved JAK-STAT signaling pathway has been implicated in lamellocyte proliferation and is required for successful encapsulation of wasp eggs. Here we show that activity of Stat92E, the D. melanogaster STAT ortholog, is induced in immune tissues following parasitoid infection. Virulent wasp species are able to suppress Stat92E activity during infection, suggesting they target JAK-STAT pathway activation as a virulence strategy. Furthermore, two wasp species (Leptopilina guineaensis and Ganaspis xanthopoda) suppress phenotypes associated with a gain-of-function mutation in hopscotch, the D. melanogaster JAK ortholog, indicating that they inhibit the activity of the core signaling components of the JAK-STAT pathway. Our data suggest that parasitoid wasp virulence factors block JAK-STAT signaling to overcome fly immune defenses. Author summary: Following infection, host immune responses are triggered to provide protection against the invading pathogen. The proper function of these responses depends on the activity of multiple immune signaling pathways. These pathways act in a coordinated manner to orchestrate the immune response, and any disruption can render the host susceptible to infection. Because of this sensitivity, many pathogen species have evolved virulence mechanisms that target host signaling pathways and disrupt their function. We are using the interaction between Drosophila melanogaster and Drosophila-infecting parasitoid wasps to study this relationship between host signaling and pathogen virulence. Parasitoids infect fly larvae, and during infection, transfer virulence protein containing venom into the host, providing a mechanism to alter host signaling. This study is focused on one key immune signaling pathway, the highly conserved JAK-STAT pathway. We find that many virulent parasitoid species restrict the activity of the host JAK-STAT pathway, providing a clue as to their virulence strategy. JAK-STAT signaling plays many additional roles in health and disease, and so this system provides a good model to further understand this important pathway. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

15. Spring 2024 Editors' Note.

Author

Borjas, Emilia and Fischer, Mary

Subjects
POLITICAL science writing, FICTIONAL characters, SHORT films, ART colleges, CREATIVE writing
Abstract

The Spring 2024 issue of The New River: A Journal of Digital Art & Literature explores themes of liminality, reality versus representation, and grief and play. The articles and artworks featured in the journal examine the blurred lines between digital and analog media, the dissonance between images and words in digital experiences, and the ways in which loss and change necessitate adaptation. Contributors to the journal include artists, writers, and scholars who offer unique perspectives on these topics. The journal encourages readers to engage with the pieces presented and consider the complexities of our digital world. [Extracted from the article]

Published
2024

17. The Reemergence of Measles

Author

Klassen-Fischer, Mary K, primary, Nelson, Ann M, additional, Neafie, Ronald C, additional, Neafie, Fides A, additional, Auerbach, Aaron, additional, Baker, Thomas P, additional, Burke, Allen P, additional, Datta, Anandita A, additional, Franks, Teri J, additional, Horkayne-Szakaly, Iren, additional, Lack, Ernest E, additional, Lewin-Smith, Michael R, additional, Luiña Contreras, Alejandro, additional, Mattu, Rubina H, additional, Rush, Walter L, additional, Shick, Paul C, additional, Zhang, Yang, additional, Rentas, Francisco J, additional, and Moncur, Joel T, additional

Published
2022
Full Text
View/download PDF

20. Associations of Hearing Loss and Hearing Aid Use With Cognition, Health-Related Quality of Life, and Depressive Symptoms.

Author

Dillard, Lauren K., Pinto, Alex, Mueller, Kimberly D., Schubert, Carla R., Paulsen, Adam J., Merten, Natascha, Fischer, Mary E., Tweed, Ted S., and Cruickshanks, Karen J.

Subjects
PREVENTION of mental depression, COGNITION disorder risk factors, MENTAL depression risk factors, COGNITION disorders, WELL-being, CONFIDENCE intervals, HEARING aids, REGRESSION analysis, RISK assessment, PSYCHOLOGICAL tests, HEARING disorders, QUALITY of life, FACTOR analysis, CENTER for Epidemiologic Studies Depression Scale, DESCRIPTIVE statistics, RESEARCH funding, COGNITIVE testing, ODDS ratio, LONGITUDINAL method, DISEASE complications
Abstract

Objectives: Determine associations of hearing loss (HL) and hearing aid (HA) use with cognition, health-related quality of life (HRQoL), and depressive symptoms. Methods: Participants were from the Epidemiology of Hearing Loss Study or Beaver Dam Offspring Study. HL was defined as pure-tone average (.5–4.0 kHz) > 25 dB. A principal component analysis of 5 cognitive tasks measured cognition. The SF-12 measured mental and physical HRQoL. The Centers for Epidemiological Studies Depression Scale measured depressive symptoms (score ≥ 16). Regression models returned beta (B) coefficients or odds ratios (OR) with 95% confidence intervals. Results: This study included 3574 participants. HL (vs. none) was associated with poorer cognition (B−.12 [−.18, −.06]), mental (B−.99 [−1.65, −.33]) and physical (B−.76 [−1.50, −.03]) HRQoL, and increased odds of depressive symptoms (OR 1.49 [1.16, 1.91]). HA users had better cognition than non-users. Discussion: HL likely impacts cognition and well-being. HA use may have cognitive benefits. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

21. Original Materials

Author

Urry, Heather, Ghelfi, Eric, Christopherson, Cody, Legate, Nicole, Barrett, Tamara, Guberman, Joshua, Lenne, Richie, Fischer, Mary, Peck, Tayler, Jessa, Wiggins, Bradford, Paulk, Aidan, Sullivan, Dasan, and Wagemans, Fieke

Published
2022
Full Text
View/download PDF

22. Ethics

Author

Fischer, Mary, Arfeen, Bilal, Choudhry, Soneela, Earley, Jillian, Glass, Maegan, Gonzalez, Lucas, Hunt, Jessica, Issa, Nada, Johns, Jackie, O'Meara, Timber, Patel, Ayan, Perales, Melissa, Reyes, Alexandra, Watson, Cardiay, Weiss, Erin, turpin, robert, and Warren, Vince

Published
2022
Full Text
View/download PDF

23. Literature Review

Author

Fischer, Mary, Arfeen, Bilal, Choudhry, Soneela, Earley, Jillian, Glass, Maegan, Gonzalez, Lucas, Hunt, Jessica, Issa, Nada, Johns, Jackie, O'Meara, Timber, Patel, Ayan, Perales, Melissa, Reyes, Alexandra, Warren, Vince, Watson, Cardiay, Weiss, Erin, and turpin, robert

Published
2022
Full Text
View/download PDF

24. Materials

Author

Fischer, Mary, Arfeen, Bilal, Choudhry, Soneela, Earley, Jillian, Glass, Maegan, Gonzalez, Lucas, Hunt, Jessica, Issa, Nada, Johns, Jackie, O'Meara, Timber, Patel, Ayan, Perales, Melissa, Reyes, Alexandra, turpin, robert, Watson, Cardiay, Weiss, Erin, and Warren, Vince

Published
2022
Full Text
View/download PDF

25. Effect of disgust on judgments of moral wrongness: A multi-lab direct replication of Eskine, Kacinik, and Prinz (2011)

Author

Ghelfi, Eric, Christopherson, Cody, Legate, Nicole, Barrett, Tamara, Guberman, Joshua, Lenne, Richie, Fischer, Mary, Urry, Heather, Peck, Tayler, Jessa, Wiggins, Bradford, Paulk, Aidan, Sullivan, Dasan, and Wagemans, Fieke

Subjects
crep
Abstract

This is the homepage for the meta-analysis of CREP replications for a bad taste in the mouth (Eskine, Kacinik, Prinz, 2011).

Published
2022
Full Text
View/download PDF

26. Data, Results, and SPSS files

Author

Fischer, Mary, Arfeen, Bilal, Choudhry, Soneela, Earley, Jillian, Glass, Maegan, Gonzalez, Lucas, Hunt, Jessica, Issa, Nada, Johns, Jackie, O'Meara, Timber, Patel, Ayan, Perales, Melissa, Reyes, Alexandra, Watson, Cardiay, Weiss, Erin, turpin, robert, and Warren, Vince

Published
2022
Full Text
View/download PDF

27. Preprint

Author

Urry, Heather, Ghelfi, Eric, Christopherson, Cody, Legate, Nicole, Barrett, Tamara, Guberman, Joshua, Lenne, Richie, Fischer, Mary, Peck, Tayler, Jessa, Wiggins, Bradford, Paulk, Aidan, Sullivan, Dasan, and Wagemans, Fieke

Published
2022
Full Text
View/download PDF

28. Procedure Video

Author

Fischer, Mary, Arfeen, Bilal, Choudhry, Soneela, Earley, Jillian, Glass, Maegan, Gonzalez, Lucas, Hunt, Jessica, Issa, Nada, Johns, Jackie, O'Meara, Timber, Patel, Ayan, Perales, Melissa, Reyes, Alexandra, Watson, Cardiay, Weiss, Erin, turpin, robert, and Warren, Vince

Published
2022
Full Text
View/download PDF

29. Presentation and Manuscript

Author

Ghelfi, Eric, Christopherson, Cody, Legate, Nicole, Barrett, Tamara, Guberman, Joshua, Lenne, Richie, Fischer, Mary, Urry, Heather, Peck, Tayler, Jessa, Wiggins, Bradford, Paulk, Aidan, Sullivan, Dasan, and Wagemans, Fieke

Published
2022
Full Text
View/download PDF

31. Supplemental Material - Associations of Hearing Loss and Hearing Aid Use With Cognition, Health-Related Quality of Life, and Depressive Symptoms

Author

Dillard, Lauren K., Pinto, Alex, Mueller, Kimberly D., Schubert, Carla R., Paulsen, Adam J., Merten, Natascha, Fischer, Mary E., Tweed, Ted S., and Cruickshanks, Karen J.

Subjects
FOS: Clinical medicine, 111799 Public Health and Health Services not elsewhere classified, FOS: Health sciences, 110306 Endocrinology, 110308 Geriatrics and Gerontology
Abstract

Supplemental Material for Associations of Hearing Loss and Hearing Aid Use With Cognition, Health-Related Quality of Life and Depressive Symptoms by Lauren K. Dillard, Alex Pinto, Kimberly D. Mueller, Carla R. Schubert, Adam J. Paulsen, Natascha Merten, Mary E. Fischer, Ted S. Tweed, and Karen J. Cruickshanks in Journal of Aging and Health

Published
2022
Full Text
View/download PDF

32. sj-pdf-1-jah-10.1177_08982643211046820 – Supplemental Material for The Association of Psychological Well-Being With Sensory and Cognitive Function and Neuronal Health in Aging Adults

Author

Merten, Natascha, Pinto, Aaron Alex, Paulsen, Adam J., Chen, Yanjun, Dillard, Lauren K., Fischer, Mary E., Ryff, Carol D., Schubert, Carla R., and Cruickshanks, Karen J.

Subjects
FOS: Clinical medicine, 111799 Public Health and Health Services not elsewhere classified, FOS: Health sciences, 110306 Endocrinology, 110308 Geriatrics and Gerontology
Abstract

Supplemental Material, sj-pdf-1-jah-10.1177_08982643211046820 for The Association of Psychological Well-Being With Sensory and Cognitive Function and Neuronal Health in Aging Adults by Natascha Merten, Aaron Alex Pinto, Adam J Paulsen, Yanjun Chen, Lauren K Dillard, Mary E Fischer Carol D Ryff, Carla R Schubert and Karen J Cruickshanks in Journal of Aging and Health

Published
2022
Full Text
View/download PDF

35. The Reemergence of Measles.

Author

Klassen-Fischer, Mary K, Nelson, Ann M, Neafie, Ronald C, Neafie, Fides A, Auerbach, Aaron, Baker, Thomas P, Burke, Allen P, Datta, Anandita A, Franks, Teri J, Horkayne-Szakaly, Iren, Lack, Ernest E, Lewin-Smith, Michael R, Contreras, Alejandro Luiña, Mattu, Rubina H, Rush, Walter L, Shick, Paul C, Zhang, Yang, Rentas, Francisco J, Moncur, Joel T, and Luiña Contreras, Alejandro

Subjects
*EMERGING infectious diseases, *MEASLES, *MULTINUCLEATED giant cells, *PATHOLOGISTS, *BACTERIAL diseases, *NOCARDIOSIS
Abstract

Objectives: Present-day pathologists may be unfamiliar with the histopathologic features of measles, which is a reemerging disease. Awareness of these features may enable early diagnosis of measles in unsuspected cases, including those with an atypical presentation. Using archived tissue samples from historic patients, a unique source of histopathologic information about measles and other reemerging infectious diseases, we performed a comprehensive analysis of the histopathologic features of measles seen in commonly infected tissues during prodrome, active, and late phases of the disease.Methods: Subspecialty pathologists analyzed H&E-stained slides of specimens from 89 patients accessioned from 1919 to 1998 and correlated the histopathologic findings with clinical data.Results: Measles caused acute and chronic histopathologic changes, especially in the respiratory, lymphoid (including appendix and tonsils), and central nervous systems. Bacterial infections in lung and other organs contributed significantly to adverse outcomes, especially in immunocompromised patients.Conclusions: Certain histopathologic features, especially Warthin-Finkeldey cells and multinucleated giant cells without inclusions, allow pathologists to diagnose or suggest the diagnosis of measles in unsuspected cases. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

36. The Association of Psychological Well-Being With Sensory and Cognitive Function and Neuronal Health in Aging Adults.

Author

Merten, Natascha, Pinto, Aaron Alex, Paulsen, Adam J., Chen, Yanjun, Dillard, Lauren K., Fischer, Mary E., Ryff, Carol D., Schubert, Carla R., and Cruickshanks, Karen J.

Subjects
DEAFNESS prevention, NEURAL physiology, RETINAL anatomy, WELL-being, SENSES, HEARING, STRUCTURAL equation modeling, COGNITION disorders, ACTIVE aging, CROSS-sectional method, MULTIPLE regression analysis, HEALTH status indicators, DESCRIPTIVE statistics, VISUAL acuity, SMELL disorders, COGNITIVE testing, VISION disorders, MIDDLE age
Abstract

Objectives: Psychological well-being (PWB) may be a potential modifiable risk factor of age-related diseases. We aimed to determine associations of PWB with sensorineural and cognitive function and neuronal health in middle-aged adults. Methods: This study included 2039 Beaver Dam Offspring Study participants. We assessed PWB, hearing, visual acuity, contrast sensitivity impairment, olfactory impairment, cognition, and retinal (macular ganglion cell inner-plexiform layer, mGCIPL) thickness. Age-sex-education-adjusted multivariable linear, logistic regression, and generalized estimating equation models were used and then further adjusted for health-related confounders. Results: Individuals with higher PWB had better hearing functions, visual acuity, and thicker mGCIPL and reduced odds for hearing, contrast sensitivity and olfactory impairment in age-sex-education-adjusted models. Effects on mGCIPL and visual and olfactory measures decreased with adjustment. Higher PWB was associated with better cognition, better combined sensorineural-cognitive function, and decreased cognitive impairment. Discussion: Psychological well-being was associated with sensorineural-cognitive health indicating a potential of PWB interventions for healthy aging. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

37. "Shelter at Home, if You Can:" Community Vulnerability and Residential Sequestering During the Coronavirus Pandemic of 2020.

Author

Pais, Jeremy, Deener, Andrew, Fischer, Mary J., and Kline, Zachary D.

Subjects
COVID-19 pandemic, RESIDENTIAL mobility, DEMOGRAPHIC characteristics, SOCIAL distancing
Abstract

This study examines the effects of community vulnerability on residential sequestering across counties in the United States. Powerlessness and racialized politics are two hypothesized reasons for why community vulnerability affects social distancing behavior. Powerlessness is tied to the socioeconomic disadvantages of places, which intertwines with politics and race to produce a stratified response to the pandemic. We examine these dynamics with analyses that account for the disease epidemiology and other demographic factors. Data come from multiple sources, including Google's Mobility Reports and Cuebiq's Mobility Insights. Growth curve analyses find that socioeconomic disadvantage, political orientation, and racial composition independently explain the rate of change in mobility and peak residential sequestering levels during the initial outbreak. These conceptually separate dimensions of community vulnerability operate in concert, rather than as substitutes or as competing explanations, to impact the behavioral response to COVID-19. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

38. Contributors

Author

Abou-Alfa, Ghassan K., Abou-Khalil, Jad, Acher, Alexandra W., Adam, Rene, Addeo, Pietro, Agarwal, Anil Kumar, Aghayan, Davit L., Ahmed, Ola, Aizpuru, Matthew J., Allard, Marc-Antoine, Allen, Peter J., Aloia, Thomas A., Alvarez, Fernando A., Amini, Neda, Andersen, Jesper B., Anderson, Christopher D., Anteby, Roi, Arslan-Carlon, Vittoria, Aussilhou, Beatrice, Awad, Joseph, Babicky, Michele L., Bachellier, Philippe, Balachandran, Vinod P., Balogun, Fiyinfolu, Barbas, Andrew S., Barkun, Jeffrey Stewart, Bassi, Claudio, Basturk, Olca, Bayona Molano, Maria del Pilar, Beard, Rachel E., Belghiti, Jacques, Bennett, Sean A., Bernal, William, Bilchik, Anton J., Boas, Franz Edward, Bonds, Morgan, Bredbeck, Brooke C., Brody, Lynn, Brown, Karen T., Bruix, Jordi, Brunt, Elizabeth M., Büchler, Markus, Callery, Mark P., Camacho, Juan C., Campbell, Andre, Carpenter, Danielle H., Carter, C. Ross, Chan, Chung Yip, Chan, See Ching, Chandwani, Rohit, Chapman, William C., Sr., Chen, Harvey S., Cherqui, Daniel, Cheung, TT, Heng Chiow, Adrian Kah, Cho, Clifford S., Chun, Yun Shin, Clary, Bryan M., Cloyd, Jordan M., Coats, Maria V., Cohen, Joshua T., Conlon, Kevin Christopher, Connell, Louise C., Corvera, Carlos Uriel, Covey, Anne M., Crane, Christopher H., Creasy, John M., Crippin, Jeffrey S., Crispe, Nick, D’Angelica, Michael I., Da Fonseca, Leonardo Gomes, Dabbous, Hany, Danford, Christopher, Darcy, Michael, Davenport, Mark, David, Yakira, Day, Ryan William, Jonge, Jeroen de, Santibanes, Eduardo de, Santibañes, Martin de, Wilde, Roeland F. de, Delpero, Jean Robert, DeMatteo, Ronald P., DePeralta, Danielle K., Desai, Niraj M., Dickinson, Shannan M., Dickson, Euan J., DiMaio, Christopher John, Gian Do, Richard Kinh, Dokmak, Safi, Doyle, Majella, Drebin, Jeffrey A., Driedger, Michael R., Dudeja, Vikas, Dunphy, Mark, Earl, Truman M., Ebata, Tomoki, Ecker, Brett Logan, Edwin, Bjorn, Ejaz, Aslam, Dika, Imane El, Endo, Itaru, Enestvedt, C. Kristian, Fagley, R. Eliot, Fan, Sheung Tat, Farges, Olivier, Farrell, Michael Steven, Ferguson, Benjamin David, Ferrer-Fàbrega, Joana, Ferrone, Cristina R., Fields, Ryan, Fischer, Mary, Fong, Yuman, Francis-West, Philippa, Fretland, Åsmund Avdem, Fridell, Jonathan A., Friedman, Scott L., Galka, Eva, Geller, David A., Gerst, Scott R., Gerstle, Justin Theodore, Gholami, Sepideh, Gilroy, Richard, Goh, Brian K.P., Gores, Gregory J., Goss, John A., Greene, Brittany Dalia, Koerkamp, Bas Groot, Hackert, Thilo, Harrington, Kate Anne, Harrison, Ewen M., Hasegawa, Kiyoshi, Hauser, Haley, Heimbach, Julie K., Hemming, Alan W., Hernandez, Jonathan, Homma, Yuki, Iacobuzio-Donahue, Christine A., Imam, Rami, Imventarza, Oscar Cesar, Sr., Iyer, Matthew Kalahasty, Jarnagin, William R., Jayaraman, Shiva, Jepperson, Maria, Ju, Michelle R., Judge, Sean J., Kahlert, Christoph, Kambakamba, Patryk, Kangrga, Ivan, Kappadath, S. Cheenu, Karanicolas, Paul J., Katz, Seth S., Kawaguchi, Yoshikuni, Kelly, Kaitlyn J., Kemeny, Nancy E., Khan, Adeel, Khan, Tahsin M., Kim, Heung Bae, Kim, Woon Cho, Kingham, T. Peter, Kingsbery, Joseph, Kirk, Allan D., Kirks, Russell C., Jr., Klimstra, David, Knechtle, Stuart, Koea, Jonathan B., Kokudo, Norihiro, Korenblat, Kevin M., Kornblith, Lucy Zumwinkle, Krampitz, Geoffrey Wayne, Krebs, Simone, Kumamoto, Takafumi, Kwon, Choon Hyuck David, Lafaro, Kelly J., Lang, Hauke, LaQuaglia, Michael J., LaQuaglia, Michael P., LaRusso, Nicholas F., Lee, Rachel M., Lee, Ser Yee, Lencioni, Riccardo, Lendoire, Javier C., Levin, Galina, Li, Kewei, Lidsky, Michael E., Lindemann, Jessica, Linehan, David, Lopez-Solis, Roberto Carlos, Lorimer, Patrick Daniel, Ma, Ka Wing, Maithel, Shishir K., Malleo, Giuseppe, Marchegiani, Giovanni, Markmann, James F., Marsh, J. Wallis, Martin, Robert CG, II, Massani, Marco, Matsuyama, Ryusei, Maxwell, Aaron W.P., Mazza, Oscar M., McGilvray, Ian D., McIntyre, Caitlin A., McKinley, Sophia K., Melendez, Jose, Melloul, Emmanuel, Mendelsohn, Robin B., Mizuno, Takashi, Moore, Hunter Burroughs, Mosconi, Cristina, Nagaraju, Santosh, Nagino, Masato, Nagorney, David M., Nagula, Satish, Nair, Amit, Nasser-Ghodsi, Navine, Naz, Nadia, Neoptolemos, John P., Neuberger, James, Nevarez, Nicole M., Newhook, Timothy E., Noda, Takehiro, Nyberg, Scott L., O’Dwyer, Elisabeth, O’Rourke, Colm J., Odisio, Bruno C., okamura, Ryosuke, Oldhafer, Karl Jürgen, Olthoff, Kim M., Olumba, Franklin, Orloff, Susan, Orr, Christine E., O’Reilly, Eileen M., Padmanabhan, Chandrasekhar, Paniccia, Alessandro, Pappas, Theodore N., Paradis, Valérie, Parks, Rowan W., Pawlik, Timothy M., Pierce-Raglione, Cassandra D., Pillarisetty, Venu G., Pingpank, James Francis, Jr., Pitt, Henry A., Polanco, Patricio M., Pomposelli, James J., Powelson, John A., Premnath, Naveen, Qadan, Motaz, Raj, Nitya, Reddy, Srinevas, Reidy-Lagunes, Diane, Reyngold, Marsha, Rice, Teresa C., Rickert, Robert W., Roberts, John Paul, Robson, Piera Marie Cote, Rocha, Flavio G., Roll, Garrett R., Rolston, Vineet Syan, Ronot, Maxime, Rosemurgy, Alexander S., II, Rosen, Charles B., Salloum, Chady, Salvia, Roberto, Samant, Hrishikesh, Sasaki, Kazunari, Schattner, Mark A., Schnickel, Gabriel T., Schulick, Richard D., Seaton, Max E., Seo, Yongwoo David, Shah, Jigesh A., Shah, Kevin N., She, Wong Hoi, Shindoh, Junichi, Shwaartz, Chaya, Sicklick, Jason K., Siegelbaum, Robert H., Smith, Martin Derrick, Soares, Kevin C., Sofocleous, Constantinos T., Solomon, Stephen B., Srinivasa, Sanket, Starlinger, Patrick, Stecca, Tommaso, Steinharter, John A., Stewart, Camille, Stewart, Lygia, Stoll, Janis, Sucandy, Iswanto, Suhocki, Paul V., Tabibian, James H., Takemura, Nobuyuki, Tang, Laura H., Thiels, Cornelius A., Timucin, Taner, Tohme, Samer, Torzilli, Guido, Cao, Hop S. Tran, Tsang, Simon Hing Yin, Turcotte, Simon, Gulik, Thomas van, Vannucci, Andrea, Vauthey, Jean-Nicolas, Wands, Jack R., Wattacheril, Julia, Weber, Sharon Marie, Wei, Alice C., Weiss, Matthew, Weitz, Jürgen, Wisneski, Andrew David, Wolfgang, Christopher L., Yang, Dennis, Yarmohammadi, Hooman, Yeo, Charles J., Yeo, Theresa Pluth, Yopp, Adam, Zeh, Herbert, Zhou, Fangyu, Zibari, Gazi B., and Zogopoulos, George

Published
2023
Full Text
View/download PDF

39. Cutaneous Actinomycosis of the Perineum in an Immunocompetent Man

Author

Sanford, Jeffrey A., Rush, Walter L., Klassen-Fischer, Mary K., and Allbritton, Jill I.

Abstract

We present a case of primary cutaneous actinomycosis of unclear pathogenesis. A 30-year-old-man with no significant medical or surgical history presented to the emergency department with a 2-week history of a tender perineal mass. The patient denied trauma or perforating injury to the area. Examination of the area revealed an indurated, nonfluctuant, erythematous papulonodule located 2 cm from the anus. The lesion was unresponsive to oral and topical antibiotics and was therefore excised. The excision specimen revealed a dense mixed infiltrate partially filling the reticular dermis and extending into the subcutaneous fat. The infiltrate surrounded grains of basophilic material with an outer rim of eosinophilic radiating Splendore–Hoeppli material. Within the grains, filamentous bacteria were highlighted with Periodic acid-Schiff and Grocott's methenamine silver. The organisms were gram-positive and acid-fast negative. Given the clinical and histopathologic findings, actinomycosis was diagnosed. Two weeks later, the patient reported resolution of symptoms. The patient was lost to follow-up. This case highlights an unusual presentation of actinomycosis and the crucial role histopathology plays in diagnosis.

Published
2022
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results