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371 results on '"Field, Thalia S."'

2. Specialist Perspectives on the Imaging Selection of Large Vessel Occlusion in the Late Window

Author

Klein, Piers, Huo, Xiaochuan, Chen, Yimin, Abdalkader, Mohamad, Qiu, Zhongming, Nagel, Simon, Raymond, Jean, Liu, Liping, Siegler, James E., Strbian, Daniel, Field, Thalia S., Yaghi, Shadi, Qureshi, Muhammad M., Demeestere, Jelle, Puetz, Volker, Berberich, Anne, Michel, Patrik, Fischer, Urs, Kaesmacher, Johannes, Yamagami, Hiroshi, Alemseged, Fana, Tsivgoulis, Georgios, Schonewille, Wouter J., Hu, Wei, Liu, Xinfeng, Li, Chuanhui, Ji, Xunming, Drumm, Brian, Banerjee, Soma, Sacco, Simona, Sandset, Else C., Kristoffersen, Espen Saxhaug, Slade, Peter, Mikulik, Robert, Romoli, Michele, Diana, Francesco, Krishnan, Kailash, Dhillon, Permesh, Lee, Jin Soo, Kasper, Ekkehard, Dasenbrock, Hormuzdiyar, Ton, Mai Duy, Masiliūnas, Rytis, Arsovska, Anita Ante, Marto, João Pedro, Dmytriw, Adam A., Regenhardt, Robert W., Silva, Gisele Sampaio, Siepmann, Timo, Sun, Dapeng, Sang, Hongfei, Diestro, Jose Danilo, Yang, Pengfei, Mohammaden, Mahmoud H., Li, Fengli, Masoud, Hesham E., Ma, Alice, Raynald, Ganesh, Aravind, Liu, Jianmin, Meyer, Lukas, Dippel, Diederik W. J., Thomalla, Götz, Parsons, Mark, Qureshi, Adnan I., Goyal, Mayank, Yoo, Albert J., Lapergue, Bertrand, Zaidat, Osama O., Chen, Hui-Sheng, Campbell, Bruce C. V., Jovin, Tudor G., Nogueira, Raul G., Miao, Zhongrong, Saposnik, Gustavo, and Nguyen, Thanh N.

Published
2023
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4. Tenecteplase versus standard of care for minor ischaemic stroke with proven occlusion (TEMPO-2): a randomised, open label, phase 3 superiority trial

Author

Salluzzi, Marina, Blenkin, Nicole, Dueck, Ashley, Doram, Craig, Zhang, Qiao, Kenney, Carol, Ryckborst, Karla, Bohn, Shelly, Collier, Quentin, Taylor, Frances, Lethebe, B. Cord, Jambula, Anitha, Sage, Kayla, Toussaint, Lana, Save, Supryia, Lee, Jaclyn, Laham, N, Sultan, A.A., Deepak, A., Sitaram, A., Demchuk, Andrew M., Lockey, A., Micielli, A., Wadhwa, A., Arabambi, B., Graham, B., Bogiatzi, Chrysi, Doshi, Darshan, Chakraborty, D., Kim, Diana, Vasquez, D, Singh, D, Tse, Dominic, Harrison, E., Smith, E.E., Teleg, E., Klourfeld, E., Klein, G., Sebastian, I.A., Evans, J, Hegedus, J, Kromm, J, Lin, K, Ignacio, K, Ghavami, Kimia, Ismail, M., Moores, M., Panzini, M.A., Boyko, M., Almekhlafi, M.A., Newcommon, Nancy, Maraj, N., Imoukhuede, O., Volny, O., Stys, Peter, Couillard, Phillipe, Ojha, P., Eswaradass, P., Joundi, Raed, Singh, R., Asuncion, R.M., Muir, R.T., Dey, S., Mansoor, S., Wasyliw, S., Nagendra, S., Hu, Sherry, Althubait, S., Chen, S., Bal, S., Van Gaal, Stephen, Peters, Steven, Ray, Sucharita, Chaturvedi, S., Subramaniam, Suresh, Fu, Vivian, Villaluna, K., Maclean, G., King-Azote, P., Ma, C., Plecash, A., Murphy, C., Gorman, J., Wilson, L., Zhou, L., Benevente, O., Teal, P., Yip, S., Mann, S., Dewar, B., Demetroff, M., Shamloul, R., Beardshaw, R., Roberts, S., Blaquiere, D., Stotts, G., Shamy, M., Bereznyakova, O., Fahed, R., Alesefir, W., Lavoie, Suzy, Hache, A., Collard, K, Mackey, A., Gosselin-Lefebvre, S., Verreault, S., Beauchamp, B., Lambourn, L., Khaw, A., Mai, L., Sposato, L., Bres Bullrich, M., Azarpazhooh, R., Fridman, S., Kapoor, A., Southwell, A., Bardi, E., Fatakdawala, I., Kamra, M, Lopes, K., Popel, N., Norouzi, V., Liu, A., Liddy, A.M., Ghoari, B., Hawkes, C., Enriquez, C.A., Gladstone, D.J., Manosalva Alzate, H.A., Khosravani, H., Hopyan, J.J., Sivakumar, K., Son, M., Boulos, M.I., Hamind, M.A., Swartz, R.H., Murphy, R., Reiter, S., Fitzpatrick, T., Bhandari, V., Good, J., Penn, M., Naylor, M., Frost, S., Cayley, A., Akthar, F., Williams, J., Kalman, L., Crellin, L., Wiegner, R., Singh, R.S., Stewart, T., To, W., Singh, S., Pikula, A., Jaigobin, C., Carpani, F., Silver, F., Janssen, H., Schaafsma, J., del Campo, M., Alskaini, M., Rajendram, P., Fairall, P., Granfield, B., Crawford, D., Jabs, J., White, L., Sivakumar, L., Piquette, L., Nguyen, T., Nomani, A., Wagner, A., Alrohimi, A., Butt, A., D'Souza, A., Gajurel, B., Vekhande, C., Kamble, H., Kalashyan, H., Lloret, M., Benguzzi, M., Arsalan, N., Ishaque, N., Ashayeriahmadabad, R., Samiento, R., Hosseini, S., Kazi, S., Das, S., Sugumar, T., Selchen, D., Kostyrko, P., Muccilli, A., Saposnik, A.G., Vandervelde, C., Ratnayake, K., McMillan, S., Katsanos, A., Shoamanesh, A., Sahlas, D.J., Naidoo, V., Todorov, V., Toma, H., Brar, J., Lee, J., Horton, M., Shand, E., Weatherby, S., Jin, A., Durafourt, B., Jalini, S., Gardner, A., Tyson, C., Junk, E., Foster, K., Bolt, K., Sylvain, N., Maley, S., Urroz, L., Peeling, L., Kelly, M., Whelan, R., Cooley, R., Teitelbaum, J., Boutayeb, A., Moore, A., Cole, E., Waxman, L., Ben-Amor, N., Sanchez, R., Khalil, S., Nehme, A., Legault, C., Tampieri, D., Ehrensperger, E., Vieira, L., Cortes, M., Angle, M., Hannouche, M., Badawy, M., Werner, K., Wieszmuellner, S., Langer, A., Gisold, A., Zach, H., Rommer, P., Macher, S., Blechinger, S., Marik, W., Series, W., Baumgartinger, M., Krebs, S., Koski, J., Eirola, S., Ivanoff, T., Erakanto, A., Kupari, L., Sibolt, G., Panula, J., Tomppo, L., Tiainen, M., Ahlstrom, M., Martinez Majander, N., Suomalainen, O., Raty, S., Levi, C., Kerr, E., Allen, J., Kaauwai, L.P., Belevski, L., Russell, M., Ormond, S., Chew, A., Loiselle, A., Royan, A., Hughes, B., Garcia Esperon, C., Pepper, E., Miteff, F., He, J., Lycett, M., Min, M., Murray, N., Pavey, N., Starling de Barros, R., Gangadharan, S., Dunkerton, S., Waller, S., Canento Sanchez, T., Wellings, T., Edmonds, G., Whittaker, K.A., Ewing, M., Lee, P., Singkang, R., McDonald, A., Dos Santos, A., Shin, C., Jackson, D., Tsoleridis, J., Fisicchia, L., Parsons, N., Shenoy, N., Smith, S., Sharobeam, A., Balabanski, A., Park, A., Williams, C., Pavlin-Premri, D., Rodrigues, E., Alemseged, F., Ng, F., Zhao, H., Beharry, J., Ng, J.L., Williamson, J., Wong, J.Z.W., Li, K., Kwan, M.K., Valente, M., Yassi, N., Yogendrakumar, V., McNamara, B., Buchanan, C., McCarthy, C., Thomas, G., Stephens, K., Chung, M., Chung, M.F., Tang, M., Busch, T., Frost, T., Lee, R., Stuart, N., Pachani, N., Menon, A., Borojevic, B., Linton, C.M., Garcia, G., Callaly, E.P., Dewey, H., Liu, J., Chen, J., Wong, J., Nowak, K., To, K., Lizak, N.S., Bhalala, O., Park, P., Tan, P., Martins, R., Cody, R., Forbes, R., Chen, S.K., Ooi, S., Tu, S., Dang, Y.L., Ling, Z., Cranefield, J., Drew, R., Tan, A., Kurunawai, C., Harvey, J., Mahadevan, J.J., Cagi, L., Palanikumar, L., Chia, L.N., Goh, R., El-Masri, S., Urbi, B., Rapier, C., Berrill, H., McEvoy, H., Dunning, R., Kuriakose, S., Chad, T., Sapaen, V., Sabet, A., Shah, D., Yeow, D., Lilley, K., Ward, K., Mozhy Mahizhnan, M., Tan, M., Lynch, C., Coveney, S., Tobin, K., McCabe, J., Marnane, M., Murphy, S., Large, M., Moynihan, B., Boyle, K., Sanjuan, E., Sanchis, M., Boned, S., Pancorbo, O., Sala, V., Garcia, L., Garcia-Tornel, A., Juega, J., Pagola, J., Santana, K., Requena, M., Muchada, M., Olive, M., Lozano, P.J., Rubiera, M., Deck, M., Rodriguez, N., Gomez, B., Reyes Munoz, F.J., Gomez, A.S., Sanz, A.C., Garcia, E.C., Penacoba, G., Ramos, M.E., de Lera Alfonso, M., Feliu, A, Pardo, L., Ramirez, P., Murillo, A., Lopez Dominguez, D., Rodriguez, J., Terceno Izaga, M., Reina, M., Viturro, S.B., Bojaryn, U., Vera Monge, V.A., Silva Blas, Y., R Siew, R., Agustin, S J, Seet, C., Tianming, T., d'Emden, A., Murray, A., Welch, A., Hatherley, K., Day, N., Smith, W., MacRae, E., Mitchell, E.S., Mahmood, A., Elliot, J., Neilson, S., Biswas, V., Brown, C., Lewis, A., Ashton, A., Werring, D., Perry, R., Muhammad, R., Lee, Y.C., Black, A., Robinson, A., Williams, A., Banaras, A., Cahoy, C., Raingold, G., Marinescu, M., Atang, N., Bason, N., Francia, N., Obarey, S., Feerick, S., Joseph, J., Schulz, U., Irons, R., Benjamin, J., Quinn, L., Jhoots, M., Teal, R., Ford, G., Harston, G., Bains, H., Gbinigie, I., Mathieson, P., Sim, C.H., Hayter, E., Kennedy, K., Binnie, L., Priestley, N., Williams, R., Ghatala, R., Stratton, S., Blight, A., Zhang, L., Davies, A., Duffy, H., Roberts, J., Homer, J., Roberts, K., Dodd, K., Cawley, K., Martin, M., Leason, S., Cotgreave, S., Taylor, T., Nallasivan, A., Haider, S., Chakraborty, T., Webster, T., Gil, A., Martin, B., Joseph, B., Cabrera, C., Jose, D., Man, J., Aquino, J., Sebastian, S., Osterdahl, M., Kwan, M., Matthew, M., Ike, N., Bello, P., Wilding, P., Fuentes, R., Shah, R., Mashate, S., Patel, T., Nwanguma, U., Dave, V., Haber, A., Lee, A., O'Sullivan, A., Drumm, B., Dawson, A.C., Matar, T., Roberts, D., Taylor, E., Rounis, E., El-Masry, A., O'Hare, C., Kalladka, D., Jamil, S., Auger, S., Raha, O., Evans, M., Vonberg, F., Kalam, S., Ali Sheikh, A., Jenkins, I.H., George, J., Kwan, J., Blagojevic, J., Saeed, M., Haji-Coll, M., Tsuda, M., Sayed, M., Winterkron, N., Thanbirajah, N., Vittay, O., Karim, R., Smail, R.C., Gauhar, S., Elmamoun, S., Malani, S., Pralhad Kelavkar, S., Hiden, J., Ferdinand, P., Sanyal, R., Varquez, R., Smith, B., Okechukwu, C., Fox, E., Collins, E., Courtney, K., Tauro, S., Patterson, C., McShane, D., Roberts, G., McIImoyle, J., McGuire, K., Fearon, P., Gordon, P., Isaacs, K., Lucas, K., Smith, L., Dews, L., Bates, M., Lawrence, S., Heeley, S., Patel, V., Chin, Y.M., Sims, D., Littleton, E., Khaira, J., Nadar, K., Kieliszkowska, A., Sari, B., Domingos Belo, C., Smith, E., Manolo, E.Y., Aeron-Thomas, J., Doheny, M., Garcia Pardo, M., Recaman, M., Tibajia, M.C., Aissa, M., Mah, Y., Yu, T., Meenakshisundaram, S., Heller, S., Alsukhni, R., Williams, O., Farag, M., Benger, M., Engineer, A., Bayhonan, S., Conway, S., Bhalla, A., Nouvakis, D., Theochari, E., Boyle, F., Teo, J., King-Robson, J., Law, K.Y., Sztriha, L., McGovern, A., Day, D., Mitchell-Douglas, J., Francis, J., Iqbal, A., Punjabivaryani, P., Anonuevo Reyes, J., Anonuevo Reyes, M., Pauls, M., Buch, A., Hedstrom, A., Hutchinson, C., Kirkland, C., Newham, J., Wilkes, G., Fleming, L., Fleck, N., Franca, A., Chwal, B., Oldoni, C., Mantovani, G., Noll, G., Zanella, L., Soma, M., Secchi, T., Borelli, W., Rimoli, B.P., da Cunha Silva, G.H., Machado Galvao Mondin, L.A., Barbosa Cerantola, R., Imthon, A.K., Esaki, A.S., Camilo, M., Vincenzi, O.C., ds Cruz, R.R., Morillos, M.B., Riccioppa Rodrigues, G.G., Santos Ferreira, K., Pazini, A.M., Pena Pereira, M.A., de Albuquerque, A.L.A., Massote Fontanini, C.E., Matinez Rubio, C.F., dos Santos, D.T., Dias, F.A., Alves, F.F.A., Milani, C., Pegorer Santos, B., Winckler, F., De Souza, J.T., Bonome, L.A.M., Cury Silva, V.A., Teodoro, R.S., Modolo, G.P., Ferreira, N.C., Barbosa dos Santos, D.F., dos Santos Moreira, J.C., Cruz Guedes de Morais, A.B., Vieira, J., Mendes, G., de Queiroz, J.P., Coutts, Shelagh B, Ankolekar, Sandeep, Appireddy, Ramana, Arenillas, Juan F, Assis, Zarina, Bailey, Peter, Barber, Philip A, Bazan, Rodrigo, Buck, Brian H, Butcher, Ken S, Camden, Marie-Christine, Campbell, Bruce C V, Casaubon, Leanne K, Catanese, Luciana, Chatterjee, Kausik, Choi, Philip M C, Clarke, Brian, Dowlatshahi, Dar, Ferrari, Julia, Field, Thalia S, Ganesh, Aravind, Ghia, Darshan, Goyal, Mayank, Greisenegger, Stefan, Halse, Omid, Horn, Mackenzie, Hunter, Gary, Imoukhuede, Oje, Kelly, Peter J, Kennedy, James, Kleinig, Timothy J, Krishnan, Kailash, Lima, Fabricio, Mandzia, Jennifer L, Marko, Martha, Martins, Sheila O, Medvedev, George, Menon, Bijoy K, Mishra, Sachin M, Molina, Carlos, Moussaddy, Aimen, Muir, Keith W, Parsons, Mark W, Penn, Andrew M W, Pille, Arthur, Pontes-Neto, Octávio M, Roffe, Christine, Serena, Joaquin, Simister, Robert, Singh, Nishita, Spratt, Neil, Strbian, Daniel, Tham, Carol H, Wiggam, M Ivan, Williams, David J, Willmot, Mark R, Wu, Teddy, Yu, Amy Y X, Zachariah, George, Zafar, Atif, Zerna, Charlotte, and Hill, Michael D

Published
2024
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5. External validation of the SI2NCAL2C score for outcomes following cerebral venous thrombosis

Author

Klein, Piers, Shu, Liqi, Lindgren, Erik, de Winter, Maria A., Siegler, James E., Simpkins, Alexis N., Omran, Satareh Salehi, Heldner, Mirjam R., de Havenon, Adam, Abdalkader, Mohamad, al Kasab, Sami, Stretz, Christoph, Wu, Teddy Y., Wilson, Duncan, Asad, Syed Daniyal, Almallouhi, Eyad, Frontera, Jennifer, Kuohn, Lindsey, Rothstein, Aaron, Bakradze, Ekaterina, Henninger, Nils, Zubair, Adeel S., Sharma, Richa, Kerrigan, Deborah, Aziz, Yasmin, Mistry, Eva A., van Kammen, Mayte Sanchez, Tatlisumak, Turgut, Krzywicka, Katarzyna, Aguiar de Sousa, Diana, Jood, Katarina, Field, Thalia S., Yaghi, Shadi, Coutinho, Jonathan M., and Nguyen, Thanh N.

Published
2024
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7. Antithrombotic Treatment for Stroke Prevention in Cervical Artery Dissection: The STOP-CAD Study

Author

Yaghi, Shadi, Shu, Liqi, Mandel, Daniel, Leon Guerrero, Christopher R., Henninger, Nils, Muppa, Jayachandra, Affan, Muhammad, Ul Haq Lodhi, Omair, Heldner, Mirjam R., Antonenko, Kateryna, Seiffge, David, Arnold, Marcel, Salehi Omran, Setareh, Crandall, Ross, Lester, Evan, Lopez Mena, Diego, Arauz, Antonio, Nehme, Ahmad, Boulanger, Marion, Touze, Emmanuel, Sousa, Joao Andre, Sargento-Freitas, Joao, Barata, Vasco, Castro-Chaves, Paulo, Brito, Maria Teresa, Khan, Muhib, Mallick, Dania, Rothstein, Aaron, Khazaal, Ossama, Kaufmann, Josefin E., Engelter, Stefan T., Traenka, Christopher, Aguiar de Sousa, Diana, Soares, Mafalda, Rosa, Sara, Zhou, Lily W., Gandhi, Preet, Field, Thalia S., Mancini, Steven, Metanis, Issa, Leker, Ronen R., Pan, Kelly, Dantu, Vishnu, Baumgartner, Karl, Burton, Tina, Von Rennenberg, Regina, Nolte, Christian H., Choi, Richard, MacDonald, Jason, Bavarsad Shahripour, Reza, Guo, Xiaofan, Ghannam, Malik, Almajali, Mohammad, Samaniego, Edgar A., Sanchez, Sebastian, Rioux, Bastien, Zine-Eddine, Faycal, Poppe, Alexandre, Fonseca, Ana Catarina, Baptista, Maria Fortuna, Cruz, Diana, Romoli, Michele, De Marco, Giovanna, Longoni, Marco, Keser, Zafer, Griffin, Kim, Kuohn, Lindsey, Frontera, Jennifer, Amar, Jordan, Giles, James, Zedde, Marialuisa, Pascarella, Rosario, Grisendi, Ilaria, Nzwalo, Hipolito, Liebeskind, David S., Molaie, Amir, Cavalier, Annie, Kam, Wayneho, Mac Grory, Brian, Al Kasab, Sami, Anadani, Mohammad, Kicielinski, Kimberly, Eltatawy, Ali, Chervak, Lina, Chulluncuy-Rivas, Roberto, Aziz, Yasmin, Bakradze, Ekaterina, Tran, Thanh Lam, Rodrigo-Gisbert, Marc, Requena, Manuel, Saleh Velez, Faddi, Ortiz Gracia, Jorge, Mudassani, Varsha, de Havenon, Adam, Vishnu, Venugopalan Y., Yaddanapudi, Sridhara, Adams, Latasha, Browngoehl, Abigail, Ranasinghe, Tamra, Dunston, Randy, Lynch, Zachary, Penckofer, Mary, Siegler, James, Mayer, Silvia, Willey, Joshua, Zubair, Adeel, Cheng, Yee Kuang, Sharma, Richa, Marto, João Pedro, Mendes Ferreira, Vítor, Klein, Piers, Nguyen, Thanh N., Asad, Syed Daniyal, Sarwat, Zoha, Balabhadra, Anvesh, Patel, Shivam, Secchi, Thais, Martins, Sheila, Mantovani, Gabriel, Kim, Young Dae, Krishnaiah, Balaji, Elangovan, Cheran, Lingam, Sivani, Quereshi, Abid, Fridman, Sebastian, Alvarado, Alonso, Khasiyev, Farid, Linares, Guillermo, Mannino, Marina, Terruso, Valeria, Vassilopoulou, Sofia, Tentolouris, Vasilis, Martinez-Marino, Manuel, Carrasco Wall, Victor, Indraswari, Fransisca, El Jamal, Sleiman, Liu, Shilin, Alvi, Muhammad, Ali, Farman, Sarvath, Mohammed, Morsi, Rami Z., Kass-Hout, Tareq, Shi, Feina, Zhang, Jinhua, Sokhi, Dilraj, Said, Jamil, Simpkins, Alexis N., Gomez, Roberto, Sen, Shayak, Ghani, Mohammad, Elnazeir, Marwa, Xiao, Han, Kala, Narendra, Khan, Farhan, Stretz, Christoph, Mohammadzadeh, Nahid, Goldstein, Eric, and Furie, Karen

Published
2024
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10. Sex-Based Analysis of Workflow and Outcomes in Acute Ischemic Stroke Patients Treated With Alteplase Versus Tenecteplase

Author

Kim, Diana J., Singh, Nishita, Catanese, Luciana, Yu, Amy Y.X., Demchuk, Andrew M., Lloret-Villas, Mar I., Deschaintre, Yan, Coutts, Shelagh B., Khosravani, Houman, Appireddy, Ramana, Moreau, Francois, Gubitz, Gord, Tkach, Aleksander, Dowlatshahi, Dar, Medvedev, George, Mandzia, Jennifer, Pikula, Aleksandra, Shankar, Jai, Williams, Heather, Manosalva, Herbert, Siddiqui, Muzaffar, Zafar, Atif, Imoukhuede, Oje, Hunter, Gary, Phillips, Stephen, Hill, Michael D., Poppe, Alexandre Y., Ademola, Ayoola, Shamy, Michel, Bala, Fouzi, Sajobi, Tolulope T., Swartz, Richard H., Almekhlafi, Mohammed A., Menon, Bijoy K., and Field, Thalia S.

Published
2024
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14. Neuroimaging standards for research into small vessel disease—advances since 2013

Author

Duering, Marco, Biessels, Geert Jan, Brodtmann, Amy, Chen, Christopher, Cordonnier, Charlotte, de Leeuw, Frank-Erik, Debette, Stéphanie, Frayne, Richard, Jouvent, Eric, Rost, Natalia S, ter Telgte, Annemieke, Al-Shahi Salman, Rustam, Backes, Walter H, Bae, Hee-Joon, Brown, Rosalind, Chabriat, Hugues, De Luca, Alberto, deCarli, Charles, Dewenter, Anna, Doubal, Fergus N, Ewers, Michael, Field, Thalia S, Ganesh, Aravind, Greenberg, Steven, Helmer, Karl G, Hilal, Saima, Jochems, Angela C C, Jokinen, Hanna, Kuijf, Hugo, Lam, Bonnie Y K, Lebenberg, Jessica, MacIntosh, Bradley J, Maillard, Pauline, Mok, Vincent C T, Pantoni, Leonardo, Rudilosso, Salvatore, Satizabal, Claudia L, Schirmer, Markus D, Schmidt, Reinhold, Smith, Colin, Staals, Julie, Thrippleton, Michael J, van Veluw, Susanne J, Vemuri, Prashanthi, Wang, Yilong, Werring, David, Zedde, Marialuisa, Akinyemi, Rufus O, Del Brutto, Oscar H, Markus, Hugh S, Zhu, Yi-Cheng, Smith, Eric E, Dichgans, Martin, and Wardlaw, Joanna M

Published
2023
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15. Study of Rivaroxaban for Cerebral Venous Thrombosis: A Randomized Controlled Feasibility Trial Comparing Anticoagulation With Rivaroxaban to Standard-of-Care in Symptomatic Cerebral Venous Thrombosis

Author

Field, Thalia S., Dizonno, Vanessa, Almekhlafi, Mohammed A., Bala, Fouzi, Alhabli, Ibrahim, Wong, Hubert, Norena, Monica, Villaluna, Maria Karina, King-Azote, Princess, Ratnaweera, Namali, Mancini, Steven, Van Gaal, Stephen C., Wilson, Laura K., Graham, Brett R., Sposato, Luciano A., Blacquiere, Dylan, Dewar, Brian M., Boulos, Mark I., Buck, Brian H., Odier, Celine, Perera, Kanjana S., Pikula, Aleksandra, Tkach, Aleksander, Medvedev, George, Canfield, Carolyn, Mortenson, W. Ben, Nadeau, Janel O., Alshimemeri, Sohaila, Benavente, Oscar R., Demchuk, Andrew M., Dowlatshahi, Dar, Lanthier, Sylvain, Lee, Agnes Y.Y., Mandzia, Jennifer, Suryanarayan, Deepa, Weitz, Jeffrey I., Hill, Michael D., Hill, Michael, Villaluna Murray, Karina, Jones, Andrea, Matsubara, Lauren, O’Neill, Zoe, Park, Sarah, Yuan, Michelle, Saluzzi, Marina, Dueck, Ashley, McKibben, K. Ingrid, Zhang, Qiao, Benavente (chair), Oscar, Butcher (chair), Ken, Bushnell, Cheryl, de Sousa, Diana Aguiar, Hill, Michael, Benavente, Oscar, Wilson, Dr Laura, Benavente, Oscar, Lloret, Mar, Lau, Hsien Lee, Maclean, Genoveva, Mann, Sharanpal, Murphy, Colleen, Smith, Jonathan, Teal, Philip, Tse, Ming Yin (Dominic), Yip, Samuel, Naidoo, VIshaya, Brar, Jaskiran, Chen, Shuo, Horton, Myles, Hill, Michael, Save, Supriya, Althubait, Shorog, Bogiatzi, Chrysi, Boyko, Matthew, Chatuverdi, Surbhi, Coutts, Shelagh, Ganesh, Aravind, Ghavami, Kimia, Harrison, Emme, Hu, Sherry, Jambula, Anitha, Joundi, Raed, Kenney, Carol, Klein, Gary, Lin, Katie, Mansoor, Salman, Marko, Martha, Ryckborst, Karla, Sage, Kayla, Singh, Nishita, Tse, Ming Yin (Dominic), Wadhwa, Ankur, Wasiliw, Sanchea, Graham, Brett, Bhavsar, Shrijal, Bold, Kala, Maley, Sharleen, Urroz, Lilian, Foster, Kaitlyn, Junk, Emily, Corley, Scott, Gardner, Aaron, McMullen, Jennifer, Whelan, Ruth, Duff, Whitney, Tyson, Cassandra, Cooley, Regan, Hunter, Gary, Magee, Fergall, Wasyliw, Sanchea, Beauchamp, Meribeth-Ann (Beth), Lambourn, Lindsay, Ayan, Diana, Khaw, Aleksander, Mai, Lauren, Bullrich, Maria Bres, Fridman, Sebastian, Daham, Zeinab, Fahad, Robert, Shamy, Michel, Stotts, Grant, Fatadawala, Idris, Lopes, Kaitlyn, Southwell, Alisia, Bhandari, Vinaya, Fitzpatrick, Tess, Gladstone, David, Hopyan, Julia, Kamra, Maneesha, Khosravani, Houman, Liddy, Anne-Marie, Liu, Zhongyu, Popel, Najla, Sivakumar, Keith, Swartz, Richard, Yu, Amy, Fairall, Paige, Ahmed, Farhat, Jabs, Juline, White, Leah, Piquette, Lori, Shepherd, Rekha, Ishaque, Noman, Odier, Céline, Simon, Nandy-Shelwine, Lapierre, Marlene, Bereznyakova, Olena, Caporuscio, Casey Boudreau, Cauchon, Francois, Côté, Valerie, Denault, Nicole, Desciantre, Yan, Gauthier, Lyne, Gioia, Laura, Jaquin, Grégory, Jadil, Nadia, Lim, Sothun, Poppe, Alexandra, Rodriguez, Caludia, Rodriguez, Marie-Christine, Stapf, Christian, Vandervelde, Cheyenne, Ng, Kuan Huei (Kelvin), Oczkowski, Wes, Lourenco, Diane, Moreau, Cathay, Jolie, Amber, Bhagraith, Vinai, Katsanos, Aristeidis, de Sa Boasquevisque, Danielle, Ratnayake, Kanchana, McLelland, Marie, Adderly, Coleen, Elamin, Elsadig, Galloway, Camille, Smith, Michelle, Topor, Tess, Singh, Shobha, To, William, Akthar, Farhana, Casaubon, Leanne, Cayley, Anne, Crelling, Lisa, Del Campo, Martin, Gao, Mingyang, Hanna, Cresti, Khalid, Muhammad, Pham, Nga, Schaafsma, Joanna, Silver, Frank, Stewart, TIm, Tiopanas, Patricia, Wigner, Rely, and Williams, Janice

Published
2023
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16. Effect of Time to Thrombolysis on Clinical Outcomes in Patients With Acute Ischemic Stroke Treated With Tenecteplase Compared to Alteplase: Analysis From the AcT Randomized Controlled Trial

Author

Singh, Nishita, Almekhlafi, Mohammed A., Bala, Fouzi, Ademola, Ayoola, Coutts, Shelagh B., Deschaintre, Yan, Khosravani, Houman, Buck, Brian, Appireddy, Ramana, Moreau, Francois, Gubitz, Gord, Tkach, Aleksander, Catanese, Luciana, Dowlatshahi, Dar, Medvedev, George, Mandzia, Jennifer, Pikula, Aleksandra, Shankar, Jai Jai, Ghrooda, Esseeddeegg, Poppe, Alexandre Y., Williams, Heather, Field, Thalia S., Manosalva, Alejandro, Siddiqui, Muzaffar M., Zafar, Atif, Imoukhoude, Oje, Hunter, Gary, Shamy, Michel, Demchuk, Andrew M., Claggett, Brian L., Hill, Michael D., Sajobi, Tolulope T., Swartz, Richard H., and Menon, Bijoy K.

Published
2023
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18. Management of blunt cerebrovascular injuries at a Canadian level 1 trauma centre: Are we meeting the grade?

Author

D'Souza, Karan, Birnie, Blake W., Ko, Yi Man, Evans, David C., Field, Thalia S., and Joos, Emilie

Subjects
Stroke (Disease) -- Prevention, Medical research, Medicine, Experimental, Practice guidelines (Medicine) -- Evaluation, Emergency medicine -- Research, Head injuries -- Complications and side effects -- Care and treatment, Health, Health care industry
Abstract

Background: Untreated blunt cerebrovascular injuries (BCVIs) are associated with high rates of death and disability due to stroke. We assessed alignment of clinical practice at our centre with current recommendations for management of BCVIs and examined rates of new and recurrent in-hospital stroke. Methods: We retrospectively reviewed the BC Trauma Registry to identify all adult (age > 18 yr) patients with trauma with BCVIs at the largest level 1 trauma centre in British Columbia, Canada, from Apr. 1, 2013, to Mar. 31, 2018. We evaluated the registry, hospital databases and patient charts to assess alignment with guidelines for early initiation of appropriate antithrombotic therapy and follow-up imaging, and to ascertain short-term outcomes. Results: A total of 186 patients met the inclusion criteria. Just over half of BCVIs (97 [52.2%]) were Biffl grade 1-2. The majority of patients were treated with acetylsalicylic acid monotherapy (144/162 [88.9%]) or low-molecular-weight heparin (2/162 [1.2%]). Although guidelines recommend repeat imaging at 7-10 days to reassess the injury and guide duration of therapy, only 61/171 patients (35.7%) underwent repeat imaging within 7 days. Neuroimaging within 3 months after injury showed brain infarction in 29 patients (15.6%). Conclusion: Antithrombotic therapy was initiated in the majority of eligible patients with BCVIs, but completion of follow-up imaging and documentation of clear outpatient care plans were suboptimal. This finding shows the need for routine multidisciplinary management to facilitate standardization of care for this complex population. Contexte : Les traumatismes vasculaires cervicaux fermés (TVCF) non traités sont associés à des taux élevés de mortalité et d'invalidité par suite d'un défaut de vascularisation. Nous avons évalué la concordance entre la pratique clinique à notre centre et les recommandations actuelles pour la prise en charge des TVCF et mesuré les taux d'AVC perhospitaliers nouveaux et récurrents. Méthodes : Nous avons procédé à une revue rétrospective auprès du BC Trauma Registry pour recenser tous patients adultes (> 18 ans) victimes de TVCF dans le plus grand centre de traumatologie de niveau 1 de la Colombie-Britannique, au Canada, entre le 1er avril 2013 et le 31 mars 2018. Nous avons consulté le registre, les bases de données de l'hôpital et les dossiers des patients pour vérifier la conformité avec les lignes directrices en ce qui concerne l'instauration rapide du traitement antithrombotique approprié et les épreuves d'imagerie de contrôle, et pour connaître l'issue à court terme de ces traumatismes. Résultats : En tout, 186 patients répondaient aux critères d'inclusion. A peine plus de la moitié des cas de TVCF (97 [52,2%]) étaient de grade Biffl 1-2. La majorité des patients ont reçu de l'acide acétylsalicylique en monothérapie (144/162 [88,9%]) ou de l'héparine de bas poids moléculaire (2/162 [1,2%]). Même si les lignes directrices préconisaient des épreuves d'imagerie de contrôle dans les 7-10 jours pour réévaluer la situation et orienter la durée du traitement, seulement 61 patients sur 171 (35,7%) ont eu droit à de tels contrôles dans les 7 jours. Les épreuves d'imagerie cérébrale dans les 3 mois suivant le traumatisme ont montré des signes d'infarctus cérébral chez 29 patients (15,6%). Conclusion : Un traitement antithrombotique a été amorcé chez la majorité des patients admissibles présentant un TVCF, mais les contrôles d'épreuves d'imagerie et la préparation de plans de traitement post-hospitaliers clairs ont laissé à désirer. Cette observation rappelle qu'il faut une prise en charge multidisciplinaire pour mieux standardiser les soins chez cette population complexe., Traumatic blunt injury to the carotid or vertebral vessels carries a high risk of death or disability due to stroke. Although blunt cerebrovascular injuries (BCVIs) were previously thought to be [...]

Published
2022
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20. Infarcts in a New Territory: Insights From the ESCAPE-NA1 Trial

Author

Singh, Nishita, Cimflova, Petra, Ospel, Johanna Maria, Kashani, Nima, Marko, Martha, Mayank, Arnuv, Nogueira, Raul G., McTaggart, Ryan A., Demchuk, Andrew M., Poppe, Alexandre Y., Rempel, Jeremy L., Field, Thalia S., Dowlatshahi, Dar, van Adel, Brian, Swartz, Richard H., Shah, Ruchir, Sauvageau, Eric, Puetz, Volker, Silver, Frank L., Campbell, Bruce, Chapot, René, Tymianski, Michael, Goyal, Mayank, Almekhlafi, Mohammed A., and Hill, Michael D.

Published
2023
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21. Intravenous tenecteplase compared with alteplase for acute ischaemic stroke in Canada (AcT): a pragmatic, multicentre, open-label, registry-linked, randomised, controlled, non-inferiority trial

Author

Srivastava, Abhilekh, Aljammaz, Ahmed M, Akindotun, Akintomide Femi, Jin, Albert Y, Fraser, Alexander, Khaw, Alexander V, Lemnaru, Alexandru, Southwell, Alisia, Ramji, Alnar, Alvarado-Bolaños, Alonso, Mouminah, Amr, Lahlouh, Amro B, Yu, Amy Y, Alrohimi, Anas, Lavoie, Andre, Rogge, Andrea, Micieli, Andrew, Nguyen, Andrew Linh, Callaghan-Brown, Angelique, Florendo-Cumbermack, Anita, Wadhwa, Ankur, Beaudoin, Ann-Marie, Cayley, Anne, Liddy, Anne Marie, Trivedi, Anurag, Katsanos, Aristeidis H, Shuaib, Ashfaq, Butt, Asif Javed, Bereznyakova, Olena, Beauchamp, Beth, Mahlitz, Breane, Graham, Brett R, Dewar, Brian, Buck, Brian H, Durafourt, Bryce A, Holtby, Caitlin, Jackson-Tarlton, Caitlin S, Bockus, Caitlyn, Stephenson, Caroline, Galloway, Camille, Odier, Céline, Deacon, Charles, Zerna, Charlotte, Vekhande, Chetan C, Bocti, Christian, Stapf, Christian, Hawkes, Christine, Stables, Christine Anne, Bogiatzi, Chrysi, Rodriguez, Claudia, Candale-Radu, Claudia, Murphy, Colleen, Casserly, Courtney Sarah, Fok, Daniel, Boasquevisque, Danielle de Sa, Wile, Daryl, Volders, David, Sahlas, Demetrios J, Shand, Elaine, Cora, Elena Adela, Battista, Eliane Di, Stewart, Eileen, Junk, Emily, Harrison, Emma L, Frenette, Eric, Teleg, Ericka, Abdellah, Eslam, Ghrooda, Esseddeeg, Akthar, Farhana, Evoy, François, Klein, Gary M, Maclean, Genoveva, Jickling, Glen C, Hawthorne, Glenda, Boyd, Gordon, Walker, Gregory, Saposnik, Gustavo, Lau, H Lee, Badr, Hanan E, Toma, Hassanain, Kalashyan, Hayrapet, Marion-Moffet, Hugo, Grant, Ian, Fatakdawala, Idris, Beaulieu-Boire, Isabelle, Williams, Janice, Brar, Jaskiran, Rivest, Jean, Wang, Jeffrey Z, Dawe, Jessica, Stang, Jillian, Day, Joanne, Miller, Jodi, Gorman, Johnathon, Hopyan, Julia Jasmine, Lee, Julian, Kromm, Julie, Foster, Kaitlyn, Ratnayake, Kanchana, Perera, Kanjana S, Murray, Karina Villaluna, Ryckborst, Karla, Lin, Katie, Sage, Kayla, Sivakuma, Keithan, MacDonald, Kelly A, Ng, Kelvin Kuan, Merchant, Ketki, Khan, Khurshid, Ghavami, Kimia, Johnston, Kyra, Mai, Lauren M, White, Leah, Barratt, Lee, Longpre, Linda, Crellin, Lisa, Peeling, Lissa, Piquette, Lori, Lomax, Lysa Boissé, Sadeghi, Mahsa, Kamra, Maneesha, Lavoie-April, Manuel, Moores, Margaret, Bullrich, Maria Bres, McClelland, Marie, Salluzzi, Marina, Wilcox, Mark, Boulos, Mark I, Marko, Martha, Boyko, Matthew, Lantagne-Hurtubise, Maude, AlHamid, May Adel, Shawawrah, Mays, Kelly, Michael E, Thorne, Michael W D, Shamy, Michel, Bussiere, Miguel, Dominc Tse, Ming Yin, Benguzzi, Mowad, Sharma, Mukul, Horton, Myles, Newcommon, Nancy, Simon, Nandy-Shelwine, Parks, Natalie E, Sultan, Nazeem, Markovic, Nevena, Daneault, Nicole, Ishaque, Noman, Fairall, Paige, Kostyrko, Pawel B, Stys, Peter K, Teal, Philip, Couillard, Philippe, King-Azote, Princess, Collier, Quentin, Epp, Rachel, Nair, Radhika, Joundi, Raed A, Jassal, Rajive, Schneider, Raphael, Hosseini, Reza, Bouchard, Rosalie, Whelan, Ruth, Cooley, S Regan, Sujanthan, Sajeevan, Mansoor, Salman, Yip, Samuel, Wasyliw, Sanchea, Taylor, Sean W., Friedman, Sebastian, Mann, Sharan, Maley, Sharleen Weese, Chiasson, Sherry, Hu, Sherry Xueying, Althubait, Shorog, Himed, Shuhira, Chen, Shuo, Bal, Simerpreet S, Page, Stacey A, Beck, Stacey D, Woodroffe, Stephanie, Reiter, Stephanie D, Gaal, Stephen van, Peters, Steven Ray, Darvesh, Sultan, Save, Supriya, Alcock, Susan, Piercey, Susannah, Adam, Suzie, Gosselin, Sylvie, Fitzpatrick, Tess, Perron, Thomas-Louis, Stewart, Tim, Benstead, Timothy J, Naidoo, Vishaya, Wahab, Wasan Abd, Oczkowski, Wiesław, Kingston, William, Leduc, William, To, William T H, Yu, Yeyao Joe, Liu, Zhongyu A, Aljundi, Ziad Ezzat, Menon, Bijoy K, Singh, Nishita, Deschaintre, Yan, Almekhlafi, Mohammed A, Coutts, Shelagh B, Thirunavukkarasu, Sibi, Khosravani, Houman, Appireddy, Ramana, Moreau, Francois, Gubitz, Gord, Tkach, Aleksander, Catanese, Luciana, Dowlatshahi, Dar, Medvedev, George, Mandzia, Jennifer, Pikula, Aleksandra, Shankar, Jai, Williams, Heather, Field, Thalia S, Manosalva, Alejandro, Siddiqui, Muzaffar, Zafar, Atif, Imoukhuede, Oje, Hunter, Gary, Demchuk, Andrew M, Mishra, Sachin, Gioia, Laura C, Jalini, Shirin, Cayer, Caroline, Phillips, Stephen, Elamin, Elsadig, Shoamanesh, Ashkan, Subramaniam, Suresh, Kate, Mahesh, Jacquin, Gregory, Camden, Marie-Christine, Benali, Faysal, Alhabli, Ibrahim, Bala, Fouzi, Horn, MacKenzie, Stotts, Grant, Hill, Michael D, Gladstone, David J, Poppe, Alexandre, Sehgal, Arshia, Zhang, Qiao, Lethebe, Brendan Cord, Doram, Craig, Ademola, Ayoola, Kenney, Carol, Sajobi, Tolulope T, and Swartz, Richard H

Published
2022
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27. Reducing the global burden of cerebral venous thrombosis: An international research agenda

Author

Coutinho, Jonathan M, primary, van de Munckhof, Anita, additional, Aguiar de Sousa, Diana, additional, Poli, Sven, additional, Aaron, Sanjith, additional, Arauz, Antonio, additional, Conforto, Adriana B, additional, Krzywicka, Katarzyna, additional, Hiltunen, Sini, additional, Lindgren, Erik, additional, Sánchez van Kammen, Mayte, additional, Shu, Liqi, additional, Bakchoul, Tamam, additional, Belder, Rosalie, additional, van den Berg, René, additional, Boumans, Elisheva, additional, Cannegieter, Suzanne, additional, Cano-Nigenda, Vanessa, additional, Field, Thalia S, additional, Fragata, Isabel, additional, Heldner, Mirjam R, additional, Hernández-Pérez, María, additional, Klok, Frederikus A, additional, Leker, Ronen R, additional, Lucas-Neto, Lia, additional, Molad, Jeremy, additional, Nguyen, Thanh N, additional, Saaltink, Dirk-Jan, additional, Saposnik, Gustavo, additional, Sharma, Pankaj, additional, Stam, Jan, additional, Thijs, Vincent, additional, van der Vaart, Michiel, additional, Werring, David J, additional, Wong Ramos, Diana, additional, Yaghi, Shadi, additional, Yeşilot, Nilüfer, additional, Tatlisumak, Turgut, additional, Putaala, Jukka, additional, Jood, Katarina, additional, Arnold, Marcel, additional, and Ferro, José M, additional

Published
2024
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28. An interrupted time-series analysis of the impact of COVID-19 on hospitalizations for vascular events in three Canadian provinces

Author

Holodinsky, Jessalyn K., primary, Kumar, Mukesh, additional, McNaughton, Candace D., additional, Austin, Peter C., additional, Chu, Anna, additional, Hill, Michael D., additional, Norris, Colleen, additional, Field, Thalia S., additional, Lee, Douglas S., additional, Kapral, Moira K., additional, Kamal, Noreen, additional, and Yu, Amy Y.X., additional

Published
2024
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31. Quality of Life After Intravenous Thrombolysis for Acute Ischemic Stroke: Results From the AcT Randomized Controlled Trial

Author

Sajobi, Tolulope T., primary, Arimoro, Olayinka I., additional, Ademola, Ayoola, additional, Singh, Nishita, additional, Bala, Fouzi, additional, Almekhlafi, Mohammed A., additional, Deschaintre, Yan, additional, Coutts, Shelagh B., additional, Thirunavukkarasu, Sibi, additional, Khosravani, Houman, additional, Appireddy, Ramana, additional, Moreau, François, additional, Gubitz, Gordon J., additional, Tkach, Aleksander, additional, Catanese, Luciana, additional, Dowlatshahi, Dar, additional, Medvedev, George, additional, Mandzia, Jennifer, additional, Pikula, Aleksandra, additional, Shankar, Jai Shiva, additional, Williams, Heather, additional, Field, Thalia S., additional, Manosalva, Alejandro, additional, Siddiqui, Muzaffar, additional, Zafar, Atif, additional, Imoukhuede, Oje, additional, Hunter, Gary, additional, Demchuk, Andrew M., additional, Mishra, Sachin M., additional, Gioia, Laura C., additional, Jalini, Shirin, additional, Cayer, Caroline, additional, Phillips, Stephen J., additional, Elamin, Elsadig, additional, Shoamanesh, Ashkan, additional, Subramaniam, Suresh, additional, Kate, Mahesh P., additional, Jacquin, Gregory, additional, Camden, Marie-Christine, additional, Benali, Faysal, additional, Alhabli, Ibrahim, additional, Horn, MacKenzie, additional, Stotts, Grant, additional, Hill, Michael D., additional, Gladstone, David J., additional, Poppe, Alexandre Y., additional, Sehgal, Arshia, additional, Zhang, Qiao, additional, Lethebe, Brendan, additional, Doram, Craig, additional, Shamy, Michel, additional, Kenney, Carol, additional, Buck, Brian H., additional, Swartz, Richard H., additional, and Menon, Bijoy K., additional

Published
2024
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33. Contributors

Author

Adams, Harold P., primary, Adeoye, Opeolu, additional, Albers, Gregory W., additional, Alexandrov, Andrei V., additional, Amin-Hanjani, Sepideh, additional, An, Hongyu, additional, Anderson, Craig S., additional, Anrather, Josef, additional, Aparicio, Hugo J., additional, Arai, Ken, additional, Aronowski, Jaroslaw, additional, Atchaneeyasakul, Kunakorn, additional, Audebert, Heinrich, additional, Auer, Roland N., additional, Awad, Issam A., additional, Ay, Hakan, additional, Baltan, Selva, additional, Balu, Ramani, additional, Behbahani, Mandana, additional, Benavente, Oscar R., additional, Bershad, Eric M., additional, Berthaud, Jimmy V., additional, Blackburn, Spiros L., additional, Bonati, Leo H., additional, Bösel, Julian, additional, Bousser, Marie Germaine, additional, Broderick, Joseph P., additional, Brown, Martin M., additional, Brown, Wendy, additional, Brust, John C.M., additional, Bushnell, Cheryl, additional, Canhão, Patrícia, additional, Caplan, Louis R., additional, Carrión-Penagos, Julián, additional, Castellanos, Mar, additional, Caunca, Michelle R., additional, Chabriat, Hugues, additional, Chamorro, Angel, additional, Chen, Jieli, additional, Chen, Jun, additional, Chopp, Michael, additional, Christorforids, Greg, additional, Connolly, E. Sander, additional, Cramer, Steven C., additional, Cucchiara, Brett L., additional, Czap, Alexandra L., additional, Dannenbaum, Mark J., additional, Davis, Patricia H., additional, Dawson, Ted M., additional, Dawson, Valina L., additional, Day, Arthur L., additional, De Silva, T. Michael, additional, de Sousa, Diana Aguiar, additional, Del Brutto, Victor J., additional, del Zoppo, Gregory J., additional, Derdeyn, Colin P., additional, Di Tullio, Marco R., additional, Diener, Hans Christoph, additional, Diringer, Michael N., additional, Dobkin, Bruce H., additional, Dzialowski, Imanuel, additional, Elkind, Mitchell S.V., additional, Elm, Jordan, additional, Feigin, Valery L., additional, Ferro, José Manuel, additional, Field, Thalia S., additional, Fischer, Marlene, additional, Fornage, Myriam, additional, Furie, Karen L., additional, Garcia-Bonilla, Lidia, additional, Giannotta, Steven L., additional, Gobin, Y. Pierre, additional, Goldberg, Mark P., additional, Goldstein, Larry B., additional, Gonzales, Nicole R., additional, Greer, David M., additional, Grotta, James C., additional, Guo, Ruiming, additional, Gutierrez, Jose, additional, Harmel, Peter, additional, Howard, George, additional, Howard, Virginia J., additional, Hwang, Jee-Yeon, additional, Iadecola, Costantino, additional, Jahan, Reza, additional, Jickling, Glen C., additional, Joutel, Anne, additional, Kasner, Scott E., additional, Katan, Mira, additional, Kellner, Christopher P., additional, Khan, Muhib, additional, Kidwell, Chelsea S., additional, Kim, Helen, additional, Kim, Jong S., additional, Kircher, Charles E., additional, Krings, Timo, additional, Krishnamurthi, Rita V., additional, Kurth, Tobias, additional, Lansberg, Maarten G., additional, Levy, Elad I., additional, Liebeskind, David S., additional, Liew, Sook-Lei, additional, Lin, David J., additional, Lisle, Benjamin, additional, Lo, Eng H., additional, Lyden, Patrick D., additional, Maki, Takakuni, additional, Maragkos, Georgios A., additional, Marosfoi, Miklos, additional, McCullough, Louise D., additional, Meckler, Jason M., additional, Meschia, James Frederick, additional, Messé, Steven R., additional, Mocco, J, additional, Mokin, Maxim, additional, Mooney, Michael A., additional, Morgenstern, Lewis B., additional, Moskowitz, Michael A., additional, Mullen, Michael T., additional, Nägel, Steffen, additional, Nedergaard, Maiken, additional, Neira, Justin A., additional, Newman, Sarah, additional, Nicholson, Patrick J., additional, Norrving, Bo, additional, O’Donnell, Martin, additional, Ofengeim, Dimitry, additional, Ogata, Jun, additional, Ogilvy, Christopher S., additional, Orrù, Emanuele, additional, Ortega-Gutiérrez, Santiago, additional, Padrick, Matthew Maximillian, additional, Parsha, Kaushik, additional, Parsons, Mark, additional, Patel, Neil V., additional, Patel, Virendra I., additional, Pawlikowska, Ludmila, additional, Pérez, Adriana, additional, Perez-Pinzon, Miguel A., additional, Picard, John M., additional, Polster, Sean P., additional, Powers, William J., additional, Puetz, Volker, additional, Putaala, Jukka, additional, Rabinovich, Margarita, additional, Ransom, Bruce R., additional, Roa, Jorge A., additional, Rosenberg, Gary A., additional, Rossitto, Christina P., additional, Rundek, Tatjana, additional, Russin, Jonathan J., additional, Sacco, Ralph L., additional, Safouris, Apostolos, additional, Samaniego, Edgar A., additional, Sansing, Lauren H., additional, Satani, Nikunj, additional, Sattenberg, Ronald J., additional, Saver, Jeffrey L., additional, Savitz, Sean I., additional, Schmidt, Christian, additional, Seshadri, Sudha, additional, Sharma, Vijay K., additional, Sharp, Frank R., additional, Sheth, Kevin N., additional, Siddiqi, Omar K., additional, Singhal, Aneesh B., additional, Sobey, Christopher G., additional, Sommer, Clemens J., additional, Spetzler, Robert F., additional, Stapleton, Christopher J., additional, Strickland, Ben A., additional, Su, Hua, additional, Suarez, José I., additional, Takayama, Hiroo, additional, Tarsia, Joseph, additional, Tatlisumak, Turgut, additional, Thomas, Ajith J., additional, Thompson, John W., additional, Tsivgoulis, Georgios, additional, Tournier-Lasserve, Elizabeth, additional, Vidal, Gabriel, additional, Wakhloo, Ajay K., additional, Weksler, Babette B., additional, Willey, Joshua Z., additional, Wintermark, Max, additional, Wong, Lawrence K.S., additional, Xi, Guohua, additional, Xu, Jinchong, additional, Yaghi, Shadi, additional, Yamaguchi, Takenori, additional, Yang, Tuo, additional, Yasaka, Masahiro, additional, Zahuranec, Darin B., additional, Zhang, Feng, additional, Zhang, John H., additional, Zheng, Zhitong, additional, Zukin, R. Suzanne, additional, and Zweifler, Richard M., additional

Published
2022
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35. Prevalence of Walking Limitation After Acute Stroke and Its Impact on Discharge to Home

Author

Louie, Dennis R., Simpson, Lisa A., Mortenson, W. Ben, Field, Thalia S., Yao, Jennifer, and Eng, Janice J.

Subjects
Stroke (Disease) -- Care and treatment, Exercise therapy -- Patient outcomes, Walking -- Health aspects
Abstract

Objective. The purpose of this study was to provide contemporary estimates of the prevalence of lower extremity motor impairment and walking limitation after first-ever stroke and to characterize the predictive nature of early walking ability for being discharged home after acute hospitalization. Methods. In this cohort study, data were collected from a metropolitan acute care hospital in Canada at admission for 487 adults with first-ever acute ischemic or hemorrhagic stroke. Lower extremity motor impairment and walking limitation were measured using the National Institutes of Health Stroke Scale and AlphaFIM, respectively. Parallel multivariable logistic regression models were built to predict discharge home after acute hospitalization compared with further hospitalization. Results. For patients surviving a first-ever stroke, 44.1% presented with some degree of lower extremity motor impairment and 46.0% were unable to walk. In a multivariable model built around a binary classification of walking (Nagelkerke [R.sup.2] = 0.41), those with any ability to walk at admission (with or without therapist assistance) had 9.48 times greater odds of being discharged home (odds ratio = 9.48, 95% CI =6.11-14.92) than those who were unable. In a parallel multivariable model built around an ordinal classification of walking (Nagelkerke R (2) = 0.49), patients had 2.07 times greater odds (odds ratio =2.07, 95% CI = 1.8 2 -2.38) of being discharged home for each increment on a 6-point walking scale (total dependence to complete independence) assessed at acute admission. Conclusion. Approximately one-half of patients with first-ever stroke present with lower extremity weakness and walking limitation. Early walking ability is a significant predictor of returning home after acute hospitalization, independent of stroke severity. Discharge planning may be facilitated early after stroke with the familiar assessment of walking ability. Impact. An early assessment of walking function within days of stroke admission can help to streamline discharge planning. Lay Summary. Nearly one-half of all individuals who experience a first-time stroke have walking difficulty when they arrive at the hospital. The severity of the walking limitation can predict whether a patient will eventually be discharged home or go on to further hospitalization. Keywords: Lower Extremity, Prognosis, Stroke, Walking, Introduction Stroke is the second leading cause of adult mortality and disability-related disease burden worldwide, (1) often resulting in mental and physical impairments. (2) Of particular concern to individuals who [...]

Published
2022
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36. Outcomes of Cerebral Venous Thrombosis due to Vaccine-Induced Immune Thrombotic Thrombocytopenia After the Acute Phase

Author

van de Munckhof, Anita, Lindgren, Erik, Kleinig, Timothy J., Field, Thalia S., Cordonnier, Charlotte, Krzywicka, Katarzyna, Poli, Sven, Sánchez van Kammen, Mayte, Borhani-Haghighi, Afshin, Lemmens, Robin, Scutelnic, Adrian, Ciccone, Alfonso, Gattringer, Thomas, Wittstock, Matthias, Dizonno, Vanessa, Devroye, Annemie, Elkady, Ahmed, Günther, Albrecht, Cervera, Alvaro, Mengel, Annerose, Chew, Beng Lim Alvin, Buck, Brian, Zanferrari, Carla, Garcia-Esperon, Carlos, Jacobi, Christian, Soriano, Cristina, Michalski, Dominik, Zamani, Zohreh, Blacquiere, Dylan, Johansson, Elias, Cuadrado-Godia, Elisa, Vuillier, Fabrice, Bode, Felix J., Caparros, François, Maier, Frank, Tsivgoulis, Georgios, Katzberg, Hans D., Duan, Jiangang, Burrow, Jim, Pelz, Johann, Mbroh, Joshua, Oen, Joyce, Schouten, Judith, Zimmermann, Julian, Ng, Karl, Garambois, Katia, Petruzzellis, Marco, Carvalho Dias, Mariana, Ghiasian, Masoud, Romoli, Michele, Miranda, Miguel, Wronski, Miriam, Skjelland, Mona, Almasi-Dooghaee, Mostafa, Cuisenier, Pauline, Murphy, Seán, Timsit, Serge, Coutts, Shelagh B., Schönenberger, Silvia, Nagel, Simon, Hiltunen, Sini, Chatterton, Sophie, Cox, Thomas, Bartsch, Thorsten, Shaygannejad, Vahid, Mirzaasgari, Zahra, Middeldorp, Saskia, Levi, Marcel M., Kremer Hovinga, Johanna A., Jood, Katarina, Tatlisumak, Turgut, Putaala, Jukka, Heldner, Mirjam R., Arnold, Marcel, Aguiar de Sousa, Diana, Ferro, José M., and Coutinho, Jonathan M.

Published
2022
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37. Direct Oral Anticoagulants Versus Vitamin K Antagonists in Cerebral Venous Thrombosis: A Systematic Review and Meta-Analysis

Author

Yaghi, Shadi, Saldanha, Ian J., Misquith, Chelsea, Zaidat, Bashar, Shah, Asghar, Joudi, Kareem, Persaud, Bianca, Abdul Khalek, Feras, Shu, Liqi, de Havenon, Adam, Mistry, Eva A., Bakradze, Ekaterina, Goldstein, Eric D., Reagan, John, Theodorou, Aikaterini, Palaiodimou, Lina, Furie, Karen, Field, Thalia S., Tsivgoulis, Georgios, and Mac Grory, Brian

Published
2022
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38. A Randomized Controlled Trial of Tenecteplase Versus Standard of Care for Minor Ischemic Stroke with Proven Occlusion (TEMPO-2): Rational and design of a multicenter, randomized open-label clinical trial.

Author

Singh, Nishita, Kenney, Carol C, Butcher, Ken S, Buck, Brian, Barber, Philip A, Field, Thalia S, Choi, Philip M, Yu, Amy YX, Kleinig, Timothy, Appireddy, Ramana, Molina, Carlos A, Muir, Keith W, Hill, Michael D, and Coutts, Shelagh B

Abstract

Background: Almost half of acute ischemic stroke patients present with mild symptoms and there are large practice variations in their treatment globally. Individuals with an intracranial occlusion who present with minor stroke are at an increased risk of early neurological deterioration and poor outcomes. Individual patient data meta-analysis in the subgroup of patients with minor deficits showed benefit of alteplase in improving outcomes; however, this benefit has not been seen with intravenous alteplase in published randomized trials. Design: TEMPO-2 (A Randomized Controlled Trial of Tenecteplase Versus Standard of Care for Minor Ischemic Stroke With Proven Occlusion) is a prospective, open label with blinded outcome assessment, randomized controlled trial, designed to test the superiority of intravenous tenecteplase (0.25 mg/kg) over nonthrombolytic standard of care, with an estimated sample size of 1274 patients. Adult patients presenting with acute ischemic stroke with the National Institutes of Health Stroke Scale (NIHSS) ⩽ 5 and visible arterial occlusion or perfusion deficit within 12 h of onset are randomized to receive either tenecteplase (0.25 mg/kg) or standard of care. The primary outcome is return to baseline neurological functioning, measured by the modified Rankin scale (mRS) at 90 days. Safety outcomes include death and symptomatic hemorrhage (intra or extra-cranial). Other secondary outcomes include mRS 0–1, mRS 0–2, ordinal shift analysis of the mRS, partial, and full recanalization on follow-up computed tomography angiogram. Conclusion: Results of this trial will aid in determining whether there is benefit of using tenecteplase (0.25 mg/kg) in treating patients presenting with minor stroke who are at high risk of developing poor outcomes due to presence of an intracranial occlusion. Data access statement: Data will be available upon reasonable request. [ABSTRACT FROM AUTHOR]

Published
2024
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39. Effect of incomplete reperfusion patterns on clinical outcome: insights from the ESCAPE-NA1 trial.

Author

Cimflova, Petra, Singh, Nishita, Kappelhof, Manon, Ospel, Johanna M., Sehgal, Arshia, Kashani, Nima, Almekhlafi, Mohammed A., Demchuk, Andrew M., Berrouschot, Joerg, Dorn, Franziska, Kelly, Michael E., Buck, Brian H., Field, Thalia S., Dowlatshahi, Dariush, Tymianski, Michael, Hill, Michael D., and Goya, Mayank

Subjects
MYOCARDIAL infarction, ACUTE diseases, ISCHEMIA, THROMBOLYTIC therapy, RESEARCH funding, STATISTICAL sampling, TREATMENT effectiveness, RANDOMIZED controlled trials, ANGIOGRAPHY, DESCRIPTIVE statistics, LONGITUDINAL method, ODDS ratio, ISCHEMIC stroke, RESEARCH, REPERFUSION, THROMBECTOMY, CEREBRAL infarction, COMPARATIVE studies, CONFIDENCE intervals, DISEASE incidence
Abstract

Background Incomplete reperfusion (IR) after mechanical thrombectomy (MT) can be a consequence of residual occlusion, no-reflow phenomenon, or collateral counterpressure. Data on the impact of these phenomena on clinical outcome are limited. Methods Patients from the ESCAPE-NA1 trial with IR (expanded Thrombolysis In Cerebral Infarction (eTICI) 2b) were compared with those with complete or near-complete reperfusion (eTICI 2c-3) on the final angiography run. Final runs were assessed for (a) an MT-accessible occlusion, or (b) a non-MT-accessible occlusion pattern. The primary clinical outcome was modified Rankin Scale (mRS) 0--2 at 90 days. Our imaging outcome was infarction in IR territory on follow-up imaging. Unadjusted and adjusted incidence rate ratios (aIRR) with 95% confidence intervals (95% CI) were obtained. Results Of 1105 patients, 443 (40.1%) with IR and 506 (46.1%) with complete or near-complete reperfusion were included. An MT-accessible occlusion was identified in 147/443 patients (33.2%) and a non-MT-accessible occlusion in 296/443 (66.8%). As compared with patients with near-complete/complete reperfusion, patients with IR had significantly lower chances of achieving mRS 0--2 at 90 days (aIRR 0.82, 95% CI 0.74 to 0.91). Rates of mRS 0--2 were lower in the MT-accessible occlusion group as compared with the non-MT-accessible occlusion pattern group (aIRR 0.71, 95% CI 0.60 to 0.83, and aIRR 0.89, 95% CI 0.81 to 0.98, respectively). More patients with MT-accessible occlusion patterns developed infarcts in the non-reperfused territory as compared with patients with non-MT occlusion patterns (68.7% vs 46.3%). Conclusion IR was associated with worse clinical outcomes than near-complete/complete reperfusion. Two-thirds of our patients with IR had non-MT-accessible occlusion patterns which were associated with better clinical and imaging outcomes compared with those with MT-accessible occlusion patterns. [ABSTRACT FROM AUTHOR]

Published
2024
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40. Time From Hospital Arrival Until Endovascular Thrombectomy and Patient-Reported Outcomes in Acute Ischemic Stroke.

Author

Joundi, Raed A., Smith, Eric E., Ganesh, Aravind, Nogueira, Raul G., McTaggart, Ryan A., Demchuk, Andrew M., Poppe, Alexandre Y., Rempel, Jeremy L., Field, Thalia S., Dowlatshahi, Dar, Sahlas, Jim, Swartz, Richard, Shah, Ruchir, Sauvageau, Eric, Puetz, Volker, Silver, Frank L., Campbell, Bruce, Chapot, René, Tymianski, Michael, and Goyal, Mayank

Published
2024
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42. Abstract TMP14: Population-Based Intracranial Vascular Imaging for Acute Ischemic Stroke is Suboptimal

Author

Yu, Amy Y, primary, Austin, Peter C, additional, Silver, Frank L, additional, Mandzia, Jennifer L, additional, Jin, Albert, additional, Alonzo, Rea, additional, Fang, Jiming, additional, Carbonneau, Anahita, additional, Krings, Timo, additional, Linkewich, Beth, additional, Atzema, Clare, additional, Fralick, Michael, additional, Mamdani, Muhammad, additional, Swartz, Richard H, additional, Hill, Michael D, additional, Field, Thalia S, additional, and Kapral, Moira K, additional

Published
2024
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43. Abstract TMP108: External Validation of the SI 2 NCAL 2 C Score for Mortality Following Cerebral Venous Thrombosis

Author

Klein, Piers, primary, Shu, Liqi, additional, Lindgren, Erik, additional, de Winter, Maria A, additional, Siegler, James E, additional, Simpkins, Alexis N, additional, Salehi Omran, Setareh, additional, Heldner, Mirjam, additional, de Havenon, Adam H, additional, Abdalkader, Mohamad, additional, Al Kasab, Sami, additional, Stretz, Christoph, additional, Wu, Teddy, additional, Wilson, Duncan, additional, Asad, Syed Daniyal, additional, Almallouhi, Eyad, additional, Frontera, Jennifer, additional, Kuohn, Lindsey, additional, Rothstein, Aaron, additional, Bakradze, Ekaterina, additional, Henninger, Nils, additional, Zubair, Adeel S, additional, Sharma, Richa, additional, Kerrigan, Deborah, additional, Aziz, Yasmin, additional, Mistry, Eva, additional, Sanchez van Kammen, Mayte, additional, Tatlisumak, Turgut, additional, Krzywicka, Katarzyna, additional, Aguiar De Sousa, Diana, additional, Jood, Katarina, additional, Field, Thalia S, additional, Yaghi, Shadi, additional, Coutinho, Jonathan M, additional, and Nguyen, Thanh N, additional

Published
2024
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45. Abstract WMP11: Intravenous Thrombolysis in Patients Without versus With Visible Occlusion: A Secondary Analysis From the AcT Trial

Author

Siddiqi, A. Zohaib, primary, Ignacio, Katrina H, additional, Bala, Fouzi, additional, Ademola, Ayoola, additional, Tkach, Aleksander, additional, Buck, Brian H, additional, Catanese, Luciana, additional, Hunter, Gary, additional, Dowlatshahi, Dar, additional, Zafar, Atif, additional, Field, Thalia S, additional, Appireddy, Ramana, additional, Shamy, Michel, additional, Wadhwa, Ankur, additional, Sajobi, Tolulope, additional, Swartz, Richard H, additional, Demchuk, Andrew M, additional, Almekhlafi, Mohammed A, additional, Menon, Bijoy K, additional, and Singh, Nishita, additional

Published
2024
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46. Infarct Evolution on MR-DWI After Thrombectomy in Acute Stroke Patients Randomized to Nerinetide or Placebo

Author

Fladt, Joachim, primary, Guo, Jen, additional, Specht, Jacinta L., additional, Wang, Meng, additional, Chan, Leona L., additional, Mctaggart, Ryan, additional, Buck, Brian H., additional, Aviv, Richard, additional, Swartz, Richard H., additional, Field, Thalia S., additional, Tarpley, Jason, additional, Shah, Ruchir, additional, Goyal, Mayank, additional, Tymianski, Michael, additional, Hill, Michael D., additional, Demchuk, Andrew, additional, d'Esterre, Christopher, additional, and Barber, Philip, additional

Published
2024
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48. Reshaping the path of vascular cognitive impairment with progressive resistance training: A 12‐Month Randomized Trial

Author

Falck, Ryan S, primary, Tam, Roger, additional, Dao, Elizabeth, additional, Barha, Cindy K, additional, Hsiung, Ging‐Yuek Robin, additional, Crockett, Rachel A, additional, Alkeridy, Walid Ahmed, additional, Best, John R., additional, Grant, Sofia, additional, Field, Thalia S., additional, Silva, Nárlon Cássio Boa Sorte, additional, Brinke, Lisanne F Ten, additional, and Liu‐Ambrose, Teresa, additional

Published
2023
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