1. Utility of the Repetitive Nerve Stimulation Test and Needle EMG in the Trapezius Muscle for the Early Diagnosis of ALS.
- Author
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Takahashi K, Hamada Y, Kobayashi M, Kobayashi S, Kanbayashi T, Hatanaka Y, Nakayama T, Imafuku I, Matsuno H, Iguchi Y, Katada F, Fukutake T, Ando T, Mikata T, Usui T, Uchino K, Nishiyama K, and Sonoo M
- Subjects
- Humans, Male, Female, Middle Aged, Aged, Retrospective Studies, Adult, Early Diagnosis, Electromyography methods, Amyotrophic Lateral Sclerosis physiopathology, Amyotrophic Lateral Sclerosis diagnosis, Electric Stimulation, Superficial Back Muscles physiopathology, Sensitivity and Specificity
- Abstract
Objectives: To document the utility of decremental responses in the repetitive nerve stimulation test (RNS) and spontaneous activities in needle electromyography (EMG) in the trapezius muscle for the diagnosis of amyotrophic lateral sclerosis., Methods: Subjects were retrospectively identified from our EMG database. Cervical spondylosis was represented as a disease control group. We investigated the sensitivity and specificity of RNS and EMG in the trapezius muscle and those of diagnostic criteria including the Gold Coast criteria (GCC)., Results: We reviewed 120 patients with amyotrophic lateral sclerosis and 17 patients with cervical spondylosis. "RNS or EMG" achieved the highest sensitivity (85%). The specificity was the highest for RNS (94%). Addition of RNS of the deltoid muscle achieved 98% sensitivity in the upper-limb onset amyotrophic lateral sclerosis. The sensitivity of the GCC was very high (88%)., Conclusions: Neurophysiological parameters investigated in this study having close to 100% specificities or sensitivities are useful as complements to the GCC., Competing Interests: The authors report no conflicts of interest., (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)
- Published
- 2024
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