Search

Your search keyword '"Emilia Mazzuca"' showing total 2 results
Start Over Author "Emilia Mazzuca" Publication Year Range Last 3 years
2 results on '"Emilia Mazzuca"'

1. REM sleep obstructive sleep apnoea

Author

Maria R. Bonsignore, Emilia Mazzuca, Pierpaolo Baiamonte, Bernard Bouckaert, Wim Verbeke, and Dirk A. Pevernagie

Subjects
Diseases of the respiratory system, RC705-779
Abstract

Obstructive sleep apnoea (OSA) can occur in both rapid eye movement (REM) and non-REM sleep or be limited to REM sleep, when the upper airway is most prone to collapse due to REM sleep atonia. Respiratory events are usually longer and more desaturating in REM than in NREM sleep. The prevalence of REM OSA is higher in women than in men and REM OSA usually occurs in the context of mild–moderate OSA based on the apnoea–hypopnoea index calculated for the entire sleep study. Studies have highlighted some detrimental consequences of REM OSA; for example, its frequent association with systemic hypertension and a degree of excessive daytime sleepiness similar to that found in nonsleep-stage-dependent OSA. Moreover, REM OSA could increase cardiometabolic risk. Continuous positive airway pressure (CPAP) treatment aimed at preventing REM OSA should be longer than the 4 h usually considered as good compliance, since REM sleep occurs mostly during the second half of the night. Unfortunately, patients with REM OSA show poor adherence to CPAP. Alternative non-CPAP treatments might be a good choice for REM OSA, but data are lacking. This review summarises the available data on REM OSA and critically examines the weaknesses and strengths of existing literature.

Published
2024
Full Text
View/download PDF

2. COVID-19 and non–COVID-19 pneumonia: a comparison

Author

Imusg, Chiara Di Mitri, Antonio Carroccio, Giuseppe Arcoleo, Gaetana Camarda, Maurizio Soresi, Emilia Mazzuca, Enzo Massimo Farinella, Di Mitri C., Arcoleo G., Mazzuca E., Camarda G., Farinella E.M., Soresi M., Carroccio A., Di Mitri, Chiara, Arcoleo, Giuseppe, Mazzuca, Emilia, Camarda, Gaetana, Farinella, Enzo Massimo, Soresi, Maurizio, and Carroccio, Antonio

Subjects
Male, ground-glass opacities, medicine.medical_specialty, polmonite, Pneumonia, Viral, Population, mortalità, Comorbidity, Disease, resource, elderly, Internal medicine, Pandemic, Pulmonary Medicine, medicine, Humans, pneumonia, health system, education, Pandemics, Disease burden, opacità a vetro smerigliato, Retrospective Studies, Aged, education.field_of_study, business.industry, SARS-CoV-2, Mortality rate, risorse, COVID-19, General Medicine, Middle Aged, medicine.disease, mortality, Pneumonia, ground-glass opacitie, COVID-19 Nucleic Acid Testing, HRCT, ricoveri, anziani, resources, business, sistema sanitario, Research Article, Kidney disease, hospitalization
Abstract

Background The COVID-19 pandemic has caused the relocation of huge financial resources to departments dedicated to infected patients, at the expense of those suffering from other pathologies. Aim To compare clinical features and outcomes in COVID-19 pneumonia and non-COVID-19 pneumonia patients. Patients and methods 53 patients (35 males, mean age 61.5 years) with COVID-19 pneumonia and 50 patients (32 males, mean age 72.7 years) with non-COVID-19 pneumonia, consecutively admitted between March and May 2020 were included. Clinical, laboratory and radiological data at admission were analyzed. Duration of hospitalization and mortality rates were evaluated. Results Among the non-COVID patients, mean age, presence of comorbidities (neurological diseases, chronic kidney disease and chronic obstructive pulmonary disease), Charlson Comorbidity Index and risk factors (tobacco use and protracted length of stay in geriatric healthcare facilities) were higher than in COVID patients. The non-COVID-19 pneumonia group showed a higher (24% vs. 17%), although not statistically significant in-hospital mortality rate; the average duration of hospitalization was longer for COVID patients (30 vs. 9 days, p = .0001). Conclusions In the early stages of the COVID pandemic, our centre noted no statistical difference in unadjusted in-hospital mortality between COVID and non-COVID patients. Non-COVID patients had higher Charlson Comorbidity Scores, reflecting a greater disease burden in this population.Key MessagesIn March 2020, the COVID-19 disease was declared a pandemic, with enormous consequences for the organization of health systems and in terms of human lives; this has caused the relocation of huge financial resources to departments dedicated to infected patients, at the expense of those suffering from other pathologies.Few published reports have compared COVID-19 and non-COVID-19 pneumonia. In our study, performed in a geographic area with a low prevalence of SARS-CoV-2 infection, we found few statistically significant differences in terms of clinical characteristics between the two groups analyzed.In the early stages of the COVID pandemic, our centre noted no statistical difference in unadjusted in-hospital mortality between COVID and non-COVID patients. Non-COVID patients had higher Charlson Comorbidity Scores, reflecting a greater disease burden in this population

Published
2021

Catalog

Books, media, physical & digital resources
See catalog results