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Your search keyword '"Ducheix, Simon"' showing total 5 results
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5 results on '"Ducheix, Simon"'

1. Empagliflozin mitigates metabolic dysfunction‐associated steatotic liver disease by reducing de novo lipogenesis in a mouse model of lipoatrophic diabetes.

Author

Smati, Sarra, Sotin, Thibaud, Deniel, Perrine, Ducheix, Simon, Joubert, Michael, Arnaud, Lucie, Hadjadj, Samy, Cariou, Bertrand, Le May, Cédric, and Prieur, Xavier

Subjects
SODIUM-glucose cotransporters, EMPAGLIFLOZIN, LABORATORY mice, LIVER diseases, SODIUM-glucose cotransporter 2 inhibitors, ANIMAL disease models
Abstract

A study published in the journal Diabetes, Obesity & Metabolism explores the effects of the drug empagliflozin on metabolic dysfunction-associated steatotic liver disease (MASLD) in a mouse model of lipoatrophic diabetes. The researchers found that empagliflozin prevented the development of MASLD in mice and reduced liver steatosis in older mice. The drug achieved these effects by reducing de novo lipogenesis, the process by which the liver produces new fat. The study suggests that empagliflozin could be a potential therapeutic option for managing MASLD associated with lipodystrophies. [Extracted from the article]

Published
2024
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2. Lipidomic analysis of adipose-derived extracellular vesicles reveals specific EV lipid sorting informative of the obesity metabolic state

Author

Blandin, Alexia, primary, Dugail, Isabelle, additional, Hilairet, Grégory, additional, Ponnaiah, Maharajah, additional, Ghesquière, Valentine, additional, Froger, Josy, additional, Ducheix, Simon, additional, Fizanne, Lionel, additional, Boursier, Jérôme, additional, Cariou, Bertrand, additional, Lhomme, Marie, additional, and Le Lay, Soazig, additional

Published
2023
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3. Reduction in gut‐derived MUFAs via intestinal stearoyl‐CoA desaturase 1 deletion drives susceptibility to NAFLD and hepatocarcinoma

Author

Ducheix, Simon, primary, Piccinin, Elena, additional, Peres, Claudia, additional, Garcia‐Irigoyen, Oihane, additional, Bertrand‐Michel, Justine, additional, Fouache, Allan, additional, Cariello, Marica, additional, Lobaccaro, Jean‐Marc, additional, Guillou, Hervé, additional, Sabbà, Carlo, additional, Ntambi, James M., additional, and Moschetta, Antonio, additional

Published
2022
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4. Seipin localizes at endoplasmic-reticulum-mitochondria contact sites to control mitochondrial calcium import and metabolism in adipocytes

Author

Combot, Yoann, primary, Salo, Veijo T., additional, Chadeuf, Gilliane, additional, Hölttä, Maarit, additional, Ven, Katharina, additional, Pulli, Ilari, additional, Ducheix, Simon, additional, Pecqueur, Claire, additional, Renoult, Ophélie, additional, Lak, Behnam, additional, Li, Shiqian, additional, Karhinen, Leena, additional, Belevich, Ilya, additional, Le May, Cedric, additional, Rieusset, Jennifer, additional, Le Lay, Soazig, additional, Croyal, Mikael, additional, Tayeb, Karim Si, additional, Vihinen, Helena, additional, Jokitalo, Eija, additional, Törnquist, Kid, additional, Vigouroux, Corinne, additional, Cariou, Bertrand, additional, Magré, Jocelyne, additional, Larhlimi, Abdelhalim, additional, Ikonen, Elina, additional, and Prieur, Xavier, additional

Published
2022
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