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Your search keyword '"De Marinis, Elisabetta"' showing total 9 results
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9 results on '"De Marinis, Elisabetta"'

1. MCL1 regulates AML cells metabolism via direct interaction with HK2. Metabolic signature at onset predicts overall survival in AMLs’ patients

Author

Catalano, Gianfranco, Zaza, Alessandra, Banella, Cristina, Pelosi, Elvira, Castelli, Germana, de Marinis, Elisabetta, Smigliani, Ariela, Travaglini, Serena, Ottone, Tiziana, Divona, Mariadomenica, Del Principe, Maria Ilaria, Buccisano, Francesco, Maurillo, Luca, Ammatuna, Emanuele, Testa, Ugo, Nervi, Clara, Venditti, Adriano, Voso, Maria Teresa, and Noguera, Nelida Ines

Published
2023
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4. Nuclear miRNAs: Gene Regulation Activities.

Author

Billi, Monia, De Marinis, Elisabetta, Gentile, Martina, Nervi, Clara, and Grignani, Francesco

Subjects
*GENETIC regulation, *MICRORNA, *GENE enhancers, *MESSENGER RNA, *NON-coding RNA, *GENE expression
Abstract

MicroRNAs (miRNAs) are small non-coding RNAs which contribute to the regulation of many physiological and pathological processes. Conventionally, miRNAs perform their activity in the cytoplasm where they regulate gene expression by interacting in a sequence-specific manner with mature messenger RNAs. Recent studies point to the presence of mature miRNAs in the nucleus. This review summarizes current findings regarding the molecular activities of nuclear miRNAs. These molecules can regulate gene expression at the transcriptional level by directly binding DNA on the promoter or the enhancer of regulated genes. miRNAs recruit different protein complexes to these regions, resulting in activation or repression of transcription, through a number of molecular mechanisms. Hematopoiesis is presented as a paradigmatic biological process whereby nuclear miRNAs possess a relevant regulatory role. Nuclear miRNAs can influence gene expression by affecting nuclear mRNA processing and by regulating pri-miRNA maturation, thus impacting the biogenesis of miRNAs themselves. Overall, nuclear miRNAs are biologically active molecules that can be critical for the fine tuning of gene expression and deserve further studies in a number of physiological and pathological conditions. [ABSTRACT FROM AUTHOR]

Published
2024
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5. PB1787: PLZF-RARΑ ENHANCES METABOLIC PLASTICITY AND ROS SCAVENGING IN AML CELLS

Author

Zaza, Alessandra, primary, Gallo, Mariana, additional, Biscussi, Brunella, additional, Angelini, Daniela F., additional, Pasqualini, Gloria, additional, Catalano, Gianfranco, additional, De Marinis, Elisabetta, additional, Pertinhez, Thelma, additional, Voso, Maria Teresa, additional, Venditti, Adriano, additional, Nervi, Clara, additional, and Noguera, Nelida Ines, additional

Published
2023
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6. Remote Adipose Tissue-Derived Stromal Cells of Patients with Lung Adenocarcinoma Generate a Similar Malignant Microenvironment of the Lung Stromal Counterpart

Author

De Falco, Elena, primary, Bordin, Antonella, additional, Menna, Cecilia, additional, Dhori, Xhulio, additional, Picchio, Vittorio, additional, Cozzolino, Claudia, additional, De Marinis, Elisabetta, additional, Floris, Erica, additional, Maria Giorgiano, Noemi, additional, Rosa, Paolo, additional, Angelo Rendina, Erino, additional, Ibrahim, Mohsen, additional, and Calogero, Antonella, additional

Published
2023
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7. Human platelet lysate‐derived extracellular vesicles enhance angiogenesis through miR ‐126

Author

Bordin, Antonella, primary, Chirivì, Maila, additional, Pagano, Francesca, additional, Milan, Marika, additional, Iuliano, Marco, additional, Scaccia, Eleonora, additional, Fortunato, Orazio, additional, Mangino, Giorgio, additional, Dhori, Xhulio, additional, De Marinis, Elisabetta, additional, D'Amico, Alessandra, additional, Miglietta, Selenia, additional, Picchio, Vittorio, additional, Rizzi, Roberto, additional, Romeo, Giovanna, additional, Pulcinelli, Fabio, additional, Chimenti, Isotta, additional, Frati, Giacomo, additional, and De Falco, Elena, additional

Published
2022
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