295 results on '"Craik, David J."'
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2. Proximity Labelling Confirms the Involvement of Papain-Like Cysteine Proteases and Chaperones in Cyclotide Biosynthesis
3. Author Correction: Repurposing a plant peptide cyclase for targeted lysine acylation
4. Functional divergence in plant cyclotides and their role in plant defense
5. Peptide PaDBS1R6 has potent antibacterial activity on clinical bacterial isolates and integrates an immunomodulatory peptide fragment within its sequence
6. Gene-guided identifications of a structure-chimeric cyclotide viphi I from Viola philippica: Potential functions against cadmium and nematodes
7. Cyclic tachyplesin I kills proliferative, non-proliferative and drug-resistant melanoma cells without inducing resistance
8. Topology in soft and biological matter
9. Aspartic acid mutagenesis of αO-Conotoxin GeXIVA isomers reveals arginine residues crucial for inhibition of the α9α10 nicotinic acetylcholine receptor
10. Design and structural validation of peptide–drug conjugate ligands of the kappa-opioid receptor
11. Exploring the therapeutic potential of an antinociceptive and anti-inflammatory peptide from wasp venom
12. Nucleation of a key beta-turn promotes cyclotide oxidative folding
13. Scanning mutagenesis identifies residues that improve the long-term stability and insecticidal activity of cyclotide kalata B1
14. Molecular dynamics simulations support a preference of cyclotide kalata B1 for phosphatidylethanolamine phospholipids
15. Plant-based production of an orally active cyclotide for the treatment of multiple sclerosis
16. Bioproduction of Cyclic Disulfide-Rich Peptides for Drug Modalities
17. Cyclotides—Cyclic and Disulfide-Knotted Polypeptides
18. The Circular Bacteriocin enterocin NKR-5-3B has an Improved Stability Profile over Nisin
19. Neurotoxic and cytotoxic peptides underlie the painful stings of the tree nettle Urtica ferox
20. Sex-specific expression of pheromones and other signals in gravid starfish
21. Peptide-based LDH5 inhibitors enter cancer cells and impair proliferation
22. Towards a generic prototyping approach for therapeutically-relevant peptides and proteins in a cell-free translation system
23. Mutagenesis of bracelet cyclotide hyen D reveals functionally and structurally critical residues for membrane binding and cytotoxicity
24. Phage display-based discovery of cyclic peptides against the broad spectrum bacterial anti-virulence target CsrA
25. Comparative analysis of cyclotide-producing plant cell suspensions presents opportunities for cyclotide plant molecular farming
26. The prospect of substrate-based kinase inhibitors to improve target selectivity and overcome drug resistance.
27. Display Technologies for Expanding the Pharmaceutical Applications of Cyclotides.
28. Isolation and Characterization of Insecticidal Cyclotides from Viola communis
29. Seasonal tissue-specific gene expression in wild crown-of-thorns starfish reveals reproductive and stress-related transcriptional systems
30. Bioproduction of Cyclic Disulfide-Rich Peptides for Drug Modalities
31. Protocols for measuring the stability and cytotoxicity of cyclotides
32. Hijacking of N-fixing legume albumin-1 genes enables the cyclization and stabilization of defense peptides.
33. Structure and Activity of Reconstructed Pseudo‐Ancestral Cyclotides.
34. Design, Synthesis, and Structure–Activity Relationships of Novel Peptide Derivatives of the Severe Acute Respiratory Syndrome-Coronavirus‑2 Spike-Protein that Potently Inhibit Nicotinic Acetylcholine Receptors.
35. Sortase‐Catalyzed Protein Domain Inversion
36. Delivery to, and Reactivation of, the p53 Pathway in Cancer Cells Using a Grafted Cyclotide Conjugated with a Cell-Penetrating Peptide
37. The pearl jubilee of microcin J25: thirty years of research on an exceptional lasso peptide
38. Chemical synthesis of grafted cyclotides using a “plug and play” approach
39. Tertiary amide bond formation by an engineered asparaginyl ligase
40. Computational Design of α‐Conotoxins to Target Specific Nicotinic Acetylcholine Receptor Subtypes
41. Modified horseshoe crab peptides target and kill bacteria inside host cells
42. Deciphering the structure and mechanism of action of computer-designed mastoparan peptides.
43. Deciphering the structure and mechanism‐of‐action of computer‐designed mastoparan peptides
44. The Plant Defensin Ppdef1 Is a Novel Topical Treatment for Onychomycosis
45. Discovery and optimisation of conotoxin Vc1.1 and analogues with analgesic properties
46. Development of Melanocortin 4 Receptor Agonists by Exploiting Animal-Derived Macrocyclic, Disulfide-Rich Peptide Scaffolds
47. Development of a Selective Peptide κ-Opioid Receptor Antagonist by Late-Stage Functionalization with Cysteine Staples
48. Structure–Activity Relationships of Alanine Scan Mutants αO-Conotoxins GeXIVA[1,2] and GeXIVA[1,4]
49. Computational Design of α‐Conotoxins to Target Specific Nicotinic Acetylcholine Receptor Subtypes.
50. A Chemoenzymatic Approach To Produce a Cyclic Analogue of the Analgesic Drug MVIIA (Ziconotide)
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