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3. MASK-air: An OECD (Organisation for Economic Co-operation and Development) Best Practice for Public Health on Integrated Care for Chronic Diseases

Author

Czarlewski, Wienczyslawa, Haahtela, Tari, Canonica, G. Walter, Costa, Elisio M., Klimek, Ludger, Kuna, Piotr, Kupczyk, Maciej, Kvedariene, Violeta, Kulus, Marek, Larenas-Linnemann, Désirée E., Louis, Renaud, Pfaar, Oliver, Papadopoulos, Nikolaos G., Pham-Thi, Nhân, Regateiro, Frederico S., Roche, Nicolas, Samolinski, Boleslaw, Sastre, Joaquin, Scichilone, Nicola, Taborda-Barata, Luis, Valiulis, Arunas, Yorgancioglu, Arzu, Ventura, Maria Teresa, Almeida, Rute, Amaral, Rita, Ansotegui, Ignacio J., Bergmann, Karl C., Bosnic-Anticevich, Sinthia, Braido, Fulvio, Brussino, Luisa, Cardona, Victoria, Cecchi, Lorenzo, Loureiro, Claudia Chaves, Cingi, Cemal, Cruz, Alvaro A., Fokkens, Wytske J., de Vries, Govert, Gemicioglu, Bilun, Giuliano, Antonio F.M., Linuma, Tomohisa, Ivancevich, Juan Carlos, Jácome, Cristina, Kaidashev, Igor, Kraxner, Helga, Laune, Daniel, Louis, Gilles, Lourenço, Olga, Makela, Mika, Makris, Michael, Morais-Almeida, Mario, Mösges, Ralph, Maurer, Marcus, Mullol, Joaquim, Nadif, Rachel, Niedoszytko, Marek, O’Hehir, Robyn, Okamoto, Yoshitaka, Ollert, Markus, Olze, Heidi, Patella, Vincenzo, Pétré, Benoit, Puggioni, Francesca, Romantowski, Jan, Rouadi, Philip W., Reitsma, Sietze, Rivero-Yeverino, Daniela, Rodriguez-Gonzalez, Monica, Sá-Sousa, Ana, Savouré, Marine, Serpa, Faradiba S., Shamji, Mohamed H., Sheikh, Aziz, Ulrik, Charlotte Suppli, Sofiev, Mikhail, Sova, Milan, Sperl, Annette, Todo-Bom, Ana, Tomazic, Peter V., Toppila-Salmi, Sanna, Tsiligianni, Ioanna, Valovirta, Erkka, van Eerd, Michiel, Zidarn, Mihaela, Blain, Hubert, Boulet, Louis-Philippe, Brusselle, Guy, Buhl, Roland, Charpin, Denis, Casale, Thomas, Chivato, Tomas, Correia-de-Sousa, Jaime, Corrigan, Christopher, de Blay, Frédéric, Del Giacco, Stefano, Devillier, Philippe, Dykewicz, Mark, Fiocchi, Alessandro, Giovannini, Mattia, Jassem, Ewa, Jutel, Marek, Keil, Thomas, La Grutta, Stefania, Lipworth, Brian, Papi, Alberto, Pépin, Jean-Louis, Quirce, Santiago, Cordeiro, Carlos Robalo, Torres, Maria J., Usmani, Omar S., Bousquet, Jean, Sousa-Pinto, Bernardo, Anto, Josep M., Bedbrook, Anna, Fonseca, Joao A., and Zuberbier, Torsten

Published
2024
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4. Poor Rhinitis and Asthma Control Is Associated With Decreased Health-Related Quality of Life and Utilities: A MASK-air Study

Author

Czarlewski, Wienczyslawa, Bedbrook, Anna, Haahtela, Tari, Canonica, G. Walter, Costa, Elisio M., Kupczyk, Maciej, Kvedariene, Violeta, Kulus, Marek, Larenas-Linnemann, Désirée E., Pfaar, Oliver, Papadopoulos, Nikolaos G., Pham-Thi, Nhân, Regateiro, Frederico S., Roche, Nicolas, Sastre, Joaquin, Scichilone, Nicola, Taborda-Barata, Luis, Valiulis, Arunas, Yorgancioglu, Arzu, Ventura, Maria Teresa, Almeida, Rute, Amaral, Rita, Ansotegui, Ignacio J., Bergmann, Karl C., Bosnic-Anticevich, Sinthia, Braido, Fulvio, Brussino, Luisa, Cardona, Victoria, Cecchi, Lorenzo, Loureiro, Claudia Chaves, Cingi, Cemal, Cruz, Alvaro A., Fokkens, Wytske J., de Vries, Govert, Gemicioglu, Bilun, Giuliana, Antonio F.M., Linuma, Tomohisa, Ivancevich, Juan Carlos, Jácome, Cristina, Kaidashev, Igor, Kraxner, Helga, Laune, Daniel, Louis, Gilles, Lourenço, Olga, Makela, Mika, Makris, Michael, Mösges, Ralph, Maurer, Marcus, Mullol, Joaquim, Nadif, Rachel, Niedoszytko, Marek, O’Hehir, Robyn, Okamoto, Yoshitaka, Ollert, Markus, Olze, Heidi, Patella, Vincenzo, Pétré, Benoit, Puggioni, Francesca, Romantowski, Jan, Rouadi, Philip W., Reitsma, Sietze, Rivero-Yeverino, Daniela, Rodriguez-Gonzalez, Monica, Sá-Sousa, Ana, Serpa, Faradiba S., Shamji, Mohamed H., Sheikh, Aziz, Ulrik, Charlotte Suppli, Sofiev, Mikhail, Sova, Milan, Sperl, Annette, Todo-Bom, Ana, Tomazic, Peter V., Toppila-Salmi, Sanna, Tsiligianni, Ioanna, Valovirta, Erkka, van Eerd, Michiel, Zidarn, Mihaela, Blain, Hubert, Boulet, Louis-Philippe, Brusselle, Guy, Buhl, Roland, Charpin, Denis, Casale, Thomas, Chivato, Tomas, Correia-de-Sousa, Jaime, Corrigan, Christopher, de Blay, Frédéric, Del Giacco, Stefano, Devillier, Philippe, Dykewicz, Mark, Fiocchi, Alessandro, Giovannini, Mattia, Jassem, Ewa, Jutel, Marek, Keil, Thomas, La Grutta, Stefania, Lipworth, Brian, Papi, Alberto, Pépin, Jean-Louis, Quirce, Santiago, Cordeiro, Carlos Robalo, Torres, Maria J., Usmani, Omar S., Vieira, Rafael José, Leemann, Lucas, Briggs, Andrew, Pereira, Ana Margarida, Savouré, Marine, Kuna, Piotr, Morais-Almeida, Mário, Bewick, Michael, Azevedo, Luís Filipe, Louis, Renaud, Klimek, Ludger, Bahbah, Farah, Samolinski, Boleslaw, Anto, Josep M., Zuberbier, Torsten, Fonseca, João A., Bousquet, Jean, and Sousa-Pinto, Bernardo

Published
2024
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8. Impact of Dyspnea on Adults With Respiratory Symptoms Without a Defined Diagnosis

Author

Bierbrier, Jared, Gerstein, Emily, Whitmore, George A., Vandemheen, Katherine L., Bergeron, Celine, Boulet, Louis-Philippe, Cote, Andreanne, Field, Stephen K., Penz, Erika, McIvor, R. Andrew, Lemière, Catherine, Gupta, Samir, Hernandez, Paul, Mayers, Irvin, Bhutani, Mohit, Lougheed, M. Diane, Licskai, Christopher J., Azher, Tanweer, Ezer, Nicole, Ainslie, Martha, Alvarez, Gonzalo G., Mulpuru, Sunita, and Aaron, Shawn D.

Published
2024
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9. Analysis of comorbidities and multimorbidity in adult patients in the International Severe Asthma Registry

Author

Scelo, Ghislaine, Torres-Duque, Carlos A., Maspero, Jorge, Tran, Trung N., Murray, Ruth, Martin, Neil, Menzies-Gow, Andrew N., Hew, Mark, Peters, Matthew J., Gibson, Peter G., Christoff, George C., Popov, Todor A., Côté, Andréanne, Bergeron, Celine, Dorscheid, Delbert, FitzGerald, J. Mark, Chapman, Kenneth R., Boulet, Louis Philippe, Bhutani, Mohit, Sadatsafavi, Mohsen, Jiménez-Maldonado, Libardo, Duran-Silva, Mauricio, Rodriguez, Bellanid, Celis-Preciado, Carlos Andres, Cano-Rosales, Diana Jimena, Solarte, Ivan, Fernandez-Sanchez, Maria Jose, Parada-Tovar, Patricia, von Bülow, Anna, Bjerrum, Anne Sofie, Ulrik, Charlotte S., Assing, Karin Dahl, Rasmussen, Linda Makowska, Hansen, Susanne, Altraja, Alan, Bourdin, Arnaud, Taille, Camille, Charriot, Jeremy, Roche, Nicolas, Papaioannou, Andriana I., Kostikas, Konstantinos, Papadopoulos, Nikolaos G., Salvi, Sundeep, Long, Deirdre, Mitchell, Patrick D., Costello, Richard, Sirena, Concetta, Cardini, Cristina, Heffler, Enrico, Puggioni, Francesca, Canonica, Giorgio Walter, Guida, Giuseppe, Iwanaga, Takashi, Al-Ahmad, Mona, Linnemann, Désirée Larenas, Garcia, Ulises, Kuna, Piotr, Fonseca, João A., Al-Lehebi, Riyad, Koh, Mariko Siyue, Rhee, Chin Kook, Cosio, Borja G., de Llano, Luis Perez, Perng (Steve), Diahn-Warng, Huang, Erick Wan-Chun, Wang, Hao-Chien, Tsai, Ming-Ju, Mahboub, Bassam, Salameh, Laila Ibraheem Jaber, Jackson, David, Busby, John, Heaney, Liam G., Pfeffer, Paul, Goddard, Amanda Grippen, Wang, Eileen, Hoyte, Flavia, Wechsler, Michael E., Chapman, Nicholas, Katial, Rohit, Carter, Victoria, Bulathsinhala, Lakmini, Eleangovan, Neva, Ariti, Con, Lyu, Juntao, Price, David B., and Porsbjerg, Celeste

Published
2024
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10. Global access and patient safety in the transition to environmentally friendly respiratory inhalers: the Global Initiative for Asthma perspective

Author

Levy, Mark L, Bateman, Eric D, Allan, Keith, Bacharier, Leonard B, Bonini, Matteo, Boulet, Louis-Philippe, Bourdin, Arnaud, Brightling, Chris, Brusselle, Guy, Buhl, Roland, Chakaya, Muhwa Jeremiah, Cruz, Alvaro A, Drazen, Jeffrey, Ducharme, Francine M, Duijts, Liesbeth, Fleming, Louise, Inoue, Hiromasa, Ko, Fanny W S, Krishnan, Jerry A, Masekela, Refiloe, Mortimer, Kevin, Pitrez, Paulo, Salvi, Sundeep, Sheikh, Aziz, Reddel, Helen K, and Yorgancıoğlu, Arzu

Published
2023
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12. Development and validation of an electronic daily control score for asthma (e-DASTHMA): a real-world direct patient data study

Author

Sousa-Pinto, Bernardo, Jácome, Cristina, Pereira, Ana Margarida, Regateiro, Frederico S, Almeida, Rute, Czarlewski, Wienczyslawa, Kulus, Marek, Shamji, Mohamed H, Boulet, Louis-Philippe, Bonini, Matteo, Brussino, Luisa, Canonica, G Walter, Cruz, Alvaro A, Gemicioglu, Bilun, Haahtela, Tari, Kupczyk, Maciej, Kvedariene, Violeta, Larenas-Linnemann, Desirée, Louis, Renaud, Niedoszytko, Marek, Pham-Thi, Nhân, Puggioni, Francesca, Romantowski, Jan, Sastre, Joaquin, Scichilone, Nicola, Taborda-Barata, Luis, Ventura, Maria Teresa, Vieira, Rafael José, Agache, Ioana, Bedbrook, Anna, Bergmann, Karl C, Amaral, Rita, Azevedo, Luís Filipe, Bosnic-Anticevich, Sinthia, Brusselle, Guy, Buhl, Roland, Cecchi, Lorenzo, Charpin, Denis, Loureiro, Claudia Chaves, de Blay, Frédéric, Del Giacco, Stefano, Devillier, Philippe, Jassem, Ewa, Joos, Guy, Jutel, Marek, Klimek, Ludger, Kuna, Piotr, Laune, Daniel, Luna Pech, Jorge, Makela, Mika, Morais-Almeida, Mario, Nadif, Rachel, Neffen, Hugo E, Ohta, Ken, Papadopoulos, Nikolaos G, Papi, Alberto, Pétré, Benoit, Pfaar, Oliver, Yeverino, Daniela Rivero, Cordeiro, Carlos Robalo, Roche, Nicolas, Sá-Sousa, Ana, Samolinski, Boleslaw, Sheikh, Aziz, Ulrik, Charlotte Suppli, Usmani, Omar S, Valiulis, Arunas, Vandenplas, Olivier, Vieira-Marques, Pedro, Yorgancioglu, Arzu, Zuberbier, Torsten, Anto, Josep M, Fonseca, João A, and Bousquet, Jean

Published
2023
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14. Disease burden in individuals with symptomatic undiagnosed asthma or COPD

Author

Alhabeeb, Fatmah F., Whitmore, G.A., Vandemheen, Katherine L., FitzGerald, J. Mark, Bergeron, Celine, Lemière, Catherine, Boulet, Louis-Philippe, Field, Stephen K., Penz, Erika, McIvor, R. Andrew, Gupta, Samir, Mayers, Irvin, Bhutani, Mohit, Hernandez, Paul, Lougheed, Diane, Licskai, Christopher J., Azher, Tanweer, Cote, Andreanne, Ainslie, Martha, Fraser, Ian, Mahdavian, Masoud, and Aaron, Shawn D.

Published
2022
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20. Effects of Traffic-Related Air Pollution on Exercise Endurance, Dyspnea, and Cardiorespiratory Responses in Health and COPD: A Randomized, Placebo-Controlled, Crossover Trial

Author

Aaron, Shawn, Martin, James, Paré, Peter, Hogg, James, Carlsten, Christopher, Leipsic, Jonathon, Sin, Don, Tan, Wan, Guenette, Jordan, FitzGerald, Mark, Coxson, Harvey, Sadatsafavi, Mohsen, Marra, Carlo, Mayo, John, Proud, David, Leigh, Richard, Kozyrskyj, Anita, Quail, Jacqueline, Halayko, Andrew, Brownell, Marni, Parraga, Grace, Nair, Parameswaran, Stampfli, Martin, O’Byrne, Paul, Gupta, Samir, Zamel, Noe, Ratjen, Felix, Brooks, Dina, Gershon, Andrea, To, Teresa, Ungar, Wendy, Lougheed, Diane, O’Donnell, Denis, Thebaud, Bernard, Pakhale, Smita, Fergusson, Dean, Graham, Ian, Grimshaw, Jeremy, Vandemheen, Katherine, Van Dam, Anne, Benedetti, Andrea, Bourbeau, Jean, Lands, Larry, Jensen, Dennis, Landry, Jennifer, Blais, Lucie, Ducharme, Francine, Lemière, Catherine, Nuyt, Anne-Monique, Bossé, Yohan, Boulet, Louis-Philippe, Maltais, Francois, Doucet, Marieve, Hernandez, Paul, Syed, Nafeez, Ryu, Min Hyung, Dhillon, Satvir, Schaeffer, Michele R., Ramsook, Andrew H., Leung, Janice M., Ryerson, Christopher J., and Guenette, Jordan A.

Published
2022
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21. Global Initiative for Asthma Strategy 2021: Executive Summary and Rationale for Key Changes

Author

Reddel, Helen K., Bacharier, Leonard B., Bateman, Eric D., Brightling, Christopher E., Brusselle, Guy G., Buhl, Roland, Cruz, Alvaro A., Duijts, Liesbeth, Drazen, Jeffrey M., FitzGerald, J. Mark, Fleming, Louise J., Inoue, Hiromasa, Ko, Fanny W., Krishnan, Jerry A., Levy, Mark L., Lin, Jiangtao, Mortimer, Kevin, Pitrez, Paulo M., Sheikh, Aziz, Yorgancioglu, Arzu A., and Boulet, Louis-Philippe

Published
2022
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22. Poor rhinitis and asthma control is associated with decreased health-related quality-of-life and utilities: A MASK-air study

Author

Vieira, Rafael José, primary, Leemann, Lucas, additional, Briggs, Andrew, additional, Pereira, Ana Margarida, additional, Savouré, Marine, additional, Kuna, Piotr, additional, Morais-Almeida, Mário, additional, Bewick, Michael, additional, Azevedo, Luís Filipe, additional, Louis, Renaud, additional, Klimek, Ludger, additional, Bahbah, Farah, additional, Samolinski, Boleslaw, additional, Anto, Josep M., additional, Zuberbier, Torsten, additional, Fonseca, João A., additional, Bousquet, Jean, additional, Sousa-Pinto, Bernardo, additional, Czarlewski, Wienczyslawa, additional, Bedbrook, Anna, additional, Haahtela, Tari, additional, Canonica, G Walter, additional, Costa, Elisio M., additional, Kupczyk, Maciej, additional, Kvedariene, Violeta, additional, Kulus, Marek, additional, Larenas-Linnemann, Désirée E., additional, Pfaar, Oliver, additional, Papadopoulos, Nikolaos G., additional, Pham-Thi, Nhân, additional, Regateiro, Frederico S., additional, Roche, Nicolas, additional, Sastre, Joaquin, additional, Scichilone, Nicola, additional, Taborda-Barata, Luis, additional, Valiulis, Arunas, additional, Yorgancioglu, Arzu, additional, Ventura, Maria Teresa, additional, Almeida, Rute, additional, Amaral, Rita, additional, Ansotegui, Ignacio J., additional, Bergmann, Karl C., additional, Bosnic-Anticevich, Sinthia, additional, Braido, Fulvio, additional, Brussino, Luisa, additional, Cardona, Victoria, additional, Cecchi, Lorenzo, additional, Loureiro, Claudia Chaves, additional, Cingi, Cemal, additional, Cruz, Alvaro A., additional, Fokkens, Wytske J., additional, de Vries, Govert, additional, Gemicioglu, Bilun, additional, Giuliana, Antonio FM., additional, Linuma, Tomohisa, additional, Ivancevich, Juan Carlos, additional, Jácome, Cristina, additional, Kaidashev, Igor, additional, Kraxner, Helga, additional, Laune, Daniel, additional, Louis, Gilles, additional, Lourenço, Olga, additional, Makela, Mika, additional, Makris, Michael, additional, Mösges, Ralph, additional, Maurer, Marcus, additional, Mullol, Joaquim, additional, Nadif, Rachel, additional, Niedoszytko, Marek, additional, O’Hehir, Robyn, additional, Okamoto, Yoshitaka, additional, Ollert, Markus, additional, Olze, Heidi, additional, Patella, Vincenzo, additional, Pétré, Benoit, additional, Puggioni, Francesca, additional, Romantowski, Jan, additional, Rouadi, Philip W., additional, Reitsma, Sietze, additional, Rivero-Yeverino, Daniela, additional, Rodriguez-Gonzalez, Monica, additional, Sá-Sousa, Ana, additional, Serpa, Faradiba S., additional, Shamji, Mohamed H., additional, Sheikh, Aziz, additional, Ulrik, Charlotte Suppli, additional, Sofiev, Mikhail, additional, Sova, Milan, additional, Sperl, Annette, additional, Todo-Bom, Ana, additional, Tomazic, Peter V., additional, Toppila-Salmi, Sanna, additional, Tsiligianni, Ioanna, additional, Valovirta, Erkka, additional, van Eerd, Michiel, additional, Zidarn, Mihaela, additional, Blain, Hubert, additional, Boulet, Louis-Philippe, additional, Brusselle, Guy, additional, Buhl, Roland, additional, Charpin, Denis, additional, Casale, Thomas, additional, Chivato, Tomas, additional, Correia-de-Sousa, Jaime, additional, Corrigan, Christopher, additional, de Blay, Frédéric, additional, Del Giacco, Stefano, additional, Devillier, Philippe, additional, Dykewicz, Mark, additional, Fiocchi, Alessandro, additional, Giovannini, Mattia, additional, Jassem, Ewa, additional, Jutel, Marek, additional, Keil, Thomas, additional, La Grutta, Stefania, additional, Lipworth, Brian, additional, Papi, Alberto, additional, Pépin, Jean-Louis, additional, Quirce, Santiago, additional, Cordeiro, Carlos Robalo, additional, Torres, Maria J., additional, and Usmani, Omar S., additional

Published
2024
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23. MASK-air®: An OECD (Organisation for Economic Coordination and Development) Best Practice for Public Health on integrated care for chronic diseases.

Author

Bousquet, Jean, primary, Sousa-Pinto, Bernardo, additional, Anto, Josep M., additional, Bedbrook, Anna, additional, Fonseca, Joao A., additional, Zuberbier, Torsten, additional, Czarlewski, Wienczyslawa, additional, Haahtela, Tari, additional, Canonica, G Walter, additional, Costa, Elisio M., additional, Klimek, Ludger, additional, Kuna, Piotr, additional, Kupczyk, Maciej, additional, Kvedariene, Violeta, additional, Kulus, Marek, additional, Larenas-Linnemann, Désirée E., additional, Louis, Renaud, additional, Pfaar, Oliver, additional, Papadopoulos, Nikolaos G., additional, Pham-Thi, Nhân, additional, Regateiro, Frederico S., additional, Roche, Nicolas, additional, Samolinski, Boleslaw, additional, Sastre, Joaquin, additional, Scichilone, Nicola, additional, Taborda-Barata, Luis, additional, Valiulis, Arunas, additional, Yorgancioglu, Arzu, additional, Ventura, Maria Teresa, additional, Almeida, Rute, additional, Amaral, Rita, additional, Ansotegui, Ignacio J., additional, Bergmann, Karl C., additional, Bosnic-Anticevich, Sinthia, additional, Braido, Fulvio, additional, Brussino, Luisa, additional, Cardona, Victoria, additional, Cecchi, Lorenzo, additional, Loureiro, Claudia Chaves, additional, Cingi, Cemal, additional, Cruz, Alvaro A., additional, Fokkens, Wytske J., additional, de Vries, Govert, additional, Gemicioglu, Bilun, additional, Giuliano, Antonio FM., additional, Linuma, Tomohisa, additional, Ivancevich, Juan Carlos, additional, Jácome, Cristina, additional, Kaidashev, Igor, additional, Kraxner, Helga, additional, Laune, Daniel, additional, Louis, Gilles, additional, Lourenço, Olga, additional, Makela, Mika, additional, Makris, Michael, additional, Morais-Almeida, Mario, additional, Mösges, Ralph, additional, Maurer, Marcus, additional, Mullol, Joaquim, additional, Nadif, Rachel, additional, Niedoszytko, Marek, additional, O’Hehir, Robyn, additional, Okamoto, Yoshitaka, additional, Ollert, Markus, additional, Olze, Heidi, additional, Patella, Vincenzo, additional, Pétré, Benoit, additional, Puggioni, Francesca, additional, Romantowski, Jan, additional, Rouadi, Philip W., additional, Reitsma, Sietze, additional, Rivero-Yeverino, Daniela, additional, Rodriguez-Gonzalez, Monica, additional, Sá-Sousa, Ana, additional, Savouré, Marine, additional, Serpa, Faradiba S., additional, Shamji, Mohamed H., additional, Sheikh, Aziz, additional, Ulrik, Charlotte Suppli, additional, Sofiev, Mikhail, additional, Sova, Milan, additional, Sperl, Annette, additional, Todo-Bom, Ana, additional, Tomazic, Peter V., additional, Toppila-Salmi, Sanna, additional, Tsiligianni, Ioanna, additional, Valovirta, Erkka, additional, van Eerd, Michiel, additional, Zidarn, Mihaela, additional, Blain, Hubert, additional, Boulet, Louis-Philippe, additional, Brusselle, Guy, additional, Buhl, Roland, additional, Charpin, Denis, additional, Casale, Thomas, additional, Chivato, Tomas, additional, Correia-de-Sousa, Jaime, additional, Corrigan, Christopher, additional, de Blay, Frédéric, additional, Del Giacco, Stefano, additional, Devillier, Philippe, additional, Dykewicz, Mark, additional, Fiocchi, Alessandro, additional, Giovannini, Mattia, additional, Jassem, Ewa, additional, Jutel, Marek, additional, Keil, Thomas, additional, La Grutta, Stefania, additional, Lipworth, Brian, additional, Papi, Alberto, additional, Pépin, Jean-Louis, additional, Quirce, Santiago, additional, Cordeiro, Carlos Robalo, additional, Torres, Maria J., additional, and Usmani, Omar S., additional

Published
2024
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24. Defining a Severe Asthma Super-Responder: Findings from a Delphi Process

Author

Mansur, Adel, Detoraki, Aikaterini, Altraja, Alan, James, Alan, Nanzer-Kelly, Alexandra, Côté, Andréanne, Menzies-Gow, Andrew, Papaioannou, Andriana, Cheffins, Anne-Maree, Bourdin, Arnaud, Mahboub, Bassam, Lipworth, Brian, Celis-Preciado, Carlos Andrés, Torres-Duque, Carlos, Bucca, Caterina, Porsbjerg, Celeste, Ulrik, Charlotte, Corrigan, Chris, Taube, Christian, Farah, Claude, Katelaris, Constance, Langton, David, Ryan, Dermot, Larenas-Linnemann, Désirée, Zervas, Eleftherios, Heffler, Enrico, Hoyte, Flavia, Puggioni, Francesca, Christoff, George, Canonica, Giorgio Walter, Carpagnano, Giovanna Elisiana, Guida, Giuseppe, Katsoulotos, Gregory, Brusselle, Guy, Rupani, Hitashi, Jersmann, Hubertus, Clifton, Ian, Dhariwal, Jaideep, Fingleton, James, Duke, Jane, Rimmer, Janet, Douglass, Jo, Fonseca, João, van Boven, Job, Corless, John, Harrington, John, Maspero, Jorge, Miguel, José Luis, Pipatvech, Kanok, Kenny, Karrinda, Chapman, Kenneth, Kostikas, Konstantinos, Lehtimäki, Lauri, Chung, Li Ping, Heaney, Liam, Hang, Liang-Wen, Boulet, Louis-Philippe, Perez-de-Llano, Luis, Ricciardi, Luisa, Idrees, Majdy, Milanese, Manlio, Conte, Maria Elisabetta, Costantino, Maria Teresa, Siyue, Mariko Koh, Fitzgerald, Mark, Hew, Mark, Peters, Matthew, Tsai, Ming-Ju, Patel, Mitesh, Khan, Mohammad Hashim, Sadatsafavi, Mohsen, Al-Ahmad, Mona, Yacoub, Mona-Rita, De Gennaro, Mónica, Radhakrishna, Naghmeh, Hanania, Nicola Alexander, Papadopoulos, Nikolaos, Lugogo, Njira, Linaker, Norma, Crimi, Nunzio, Dennison, Paddy, Nair, Parameswaran, Mitchell, Patrick David, O’Byrne, Paul, Pfeffer, Paul, Kauppi, Paula, Hughes, Pauline, Middleton, Peter, Wark, Peter, Bardin, Philip, Fu, Pin-Kuei, Akuthota, Praveen, Chaudhuri, Rekha, Campos, Ricardo, Al-Lehebi, Riyard, Parente, Roberta, Francisco, Rovira, Wenzel, Sally, Pierachille, Santus, Pawar, Shrikant, Loukides, Stelios, Fowler, Stephen, Mackenzie, Tara, Brown, Thomas, Lee Tan, Tze, Björnsdóttir, Unnur, McDonald, Vanessa, Lawriwskyj, Veronica, Backer, Vibeke, Vasileva, Violina, Chien, Ying-Chun, Harrington, Zinta, Upham, John W., Le Lievre, Chantal, Jackson, David J., Masoli, Matthew, Wechsler, Michael E., and Price, David B.

Published
2021
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26. Relevance of individual bronchial symptoms for asthma diagnosis and control in patients with rhinitis:A MASK-air study

Author

Sousa-Pinto, Bernardo, Louis, Gilles, Vieira, Rafael J., Czarlewski, Wienczyslawa, Anto, Josep M., Amaral, Rita, Sá-Sousa, Ana, Brussino, Luisa, Canonica, G. Walter, Loureiro, Claudia Chaves, Cruz, Alvaro A., Gemicioglu, Bilun, Haahtela, Tari, Kupczyk, Maciej, Kvedariene, Violeta, Larenas-Linnemann, Desirée E., Pham-Thi, Nhân, Puggioni, Francesca, Regateiro, Frederico S., Romantowski, Jan, Sastre, Joaquin, Scichilone, Nicola, Taborda-Barata, Luis, Ventura, Maria Teresa, Agache, Ioana, Bedbrook, Anna, Benfante, Alida, Bergmann, Karl C., Bosnic-Anticevich, Sinthia, Bonini, Matteo, Boulet, Louis Philippe, Brusselle, Guy, Buhl, Roland, Cecchi, Lorenzo, Charpin, Denis, Costa, Elisio M., Del Giacco, Stefano, Jutel, Marek, Klimek, Ludger, Kuna, Piotr, Laune, Daniel, Makela, Mika, Morais-Almeida, Mario, Nadif, Rachel, Niedoszytko, Marek, Papadopoulos, Nikolaos G., Papi, Alberto, Pfaar, Oliver, Rivero-Yeverino, Daniela, Ulrik, Charlotte Suppli, Sousa-Pinto, Bernardo, Louis, Gilles, Vieira, Rafael J., Czarlewski, Wienczyslawa, Anto, Josep M., Amaral, Rita, Sá-Sousa, Ana, Brussino, Luisa, Canonica, G. Walter, Loureiro, Claudia Chaves, Cruz, Alvaro A., Gemicioglu, Bilun, Haahtela, Tari, Kupczyk, Maciej, Kvedariene, Violeta, Larenas-Linnemann, Desirée E., Pham-Thi, Nhân, Puggioni, Francesca, Regateiro, Frederico S., Romantowski, Jan, Sastre, Joaquin, Scichilone, Nicola, Taborda-Barata, Luis, Ventura, Maria Teresa, Agache, Ioana, Bedbrook, Anna, Benfante, Alida, Bergmann, Karl C., Bosnic-Anticevich, Sinthia, Bonini, Matteo, Boulet, Louis Philippe, Brusselle, Guy, Buhl, Roland, Cecchi, Lorenzo, Charpin, Denis, Costa, Elisio M., Del Giacco, Stefano, Jutel, Marek, Klimek, Ludger, Kuna, Piotr, Laune, Daniel, Makela, Mika, Morais-Almeida, Mario, Nadif, Rachel, Niedoszytko, Marek, Papadopoulos, Nikolaos G., Papi, Alberto, Pfaar, Oliver, Rivero-Yeverino, Daniela, and Ulrik, Charlotte Suppli

Abstract

Rationale It is unclear how each individual asthma symptom is associated with asthma diagnosis or control. Objectives To assess the performance of individual asthma symptoms in the identification of patients with asthma and their association with asthma control. Methods In this cross-sectional study, we assessed real-world data using the MASK-air® app. We compared the frequency of occurrence of five asthma symptoms (dyspnea, wheezing, chest tightness, fatigue and night symptoms, as assessed by the Control of Allergic Rhinitis and Asthma Test [CARAT] questionnaire) in patients with probable, possible or no current asthma. We calculated the sensitivity, specificity and predictive values of each symptom, and assessed the association between each symptom and asthma control (measured using the e-DASTHMA score). Results were validated in a sample of patients with a physician-established diagnosis of asthma. Measurement and Main Results We included 951 patients (2153 CARAT assessments), with 468 having probable asthma, 166 possible asthma and 317 no evidence of asthma. Wheezing displayed the highest specificity (90.5%) and positive predictive value (90.8%). In patients with probable asthma, dyspnea and chest tightness were more strongly associated with asthma control than other symptoms. Dyspnea was the symptom with the highest sensitivity (76.1%) and the one consistently associated with the control of asthma as assessed by e-DASTHMA. Consistent results were observed when assessing patients with a physician-made diagnosis of asthma. Conclusions Wheezing and chest tightness were the asthma symptoms with the highest specificity for asthma diagnosis, while dyspnea displayed the highest sensitivity and strongest association with asthma control., Rationale: It is unclear how each individual asthma symptom is associated with asthma diagnosis or control. Objectives: To assess the performance of individual asthma symptoms in the identification of patients with asthma and their association with asthma control. Methods: In this cross-sectional study, we assessed real-world data using the MASK-air® app. We compared the frequency of occurrence of five asthma symptoms (dyspnea, wheezing, chest tightness, fatigue and night symptoms, as assessed by the Control of Allergic Rhinitis and Asthma Test [CARAT] questionnaire) in patients with probable, possible or no current asthma. We calculated the sensitivity, specificity and predictive values of each symptom, and assessed the association between each symptom and asthma control (measured using the e-DASTHMA score). Results were validated in a sample of patients with a physician-established diagnosis of asthma. Measurement and Main Results: We included 951 patients (2153 CARAT assessments), with 468 having probable asthma, 166 possible asthma and 317 no evidence of asthma. Wheezing displayed the highest specificity (90.5%) and positive predictive value (90.8%). In patients with probable asthma, dyspnea and chest tightness were more strongly associated with asthma control than other symptoms. Dyspnea was the symptom with the highest sensitivity (76.1%) and the one consistently associated with the control of asthma as assessed by e-DASTHMA. Consistent results were observed when assessing patients with a physician-made diagnosis of asthma. Conclusions: Wheezing and chest tightness were the asthma symptoms with the highest specificity for asthma diagnosis, while dyspnea displayed the highest sensitivity and strongest association with asthma control.

Published
2024

29. Prioritization of candidate causal genes for asthma in susceptibility loci derived from UK Biobank

Author

Valette, Kim, Li, Zhonglin, Bon-Baret, Valentin, Chignon, Arnaud, Bérubé, Jean-Christophe, Eslami, Aida, Lamothe, Jennifer, Gaudreault, Nathalie, Joubert, Philippe, Obeidat, Ma’en, van den Berge, Maarten, Timens, Wim, Sin, Don D., Nickle, David C., Hao, Ke, Labbé, Catherine, Godbout, Krystelle, Côté, Andréanne, Laviolette, Michel, Boulet, Louis-Philippe, Mathieu, Patrick, Thériault, Sébastien, and Bossé, Yohan

Published
2021
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30. Association Between T2-related Comorbidities and Effectiveness of Biologics in Severe Asthma

Author

Wechsler, Michael E, primary, Scelo, Ghislaine, additional, Larenas-Linnemann, Désirée E. S., additional, Torres-Duque, Carlos A., additional, Maspero, Jorge, additional, Tran, Trung N., additional, Murray, Ruth B., additional, Martin, Neil, additional, Menzies-Gow, Andrew N., additional, Hew, Mark, additional, Peters, Matthew J, additional, Gibson, Peter G, additional, Christoff, George C., additional, Popov, Todor A., additional, Côté, Andréanne, additional, Bergeron, Celine, additional, Dorscheid, Delbert, additional, FitzGerald, J Mark, additional, Chapman, Kenneth R, additional, Boulet, Louis Philippe, additional, Bhutani, Mohit, additional, Sadatsafavi, Mohsen, additional, Jiménez-Maldonado, Libardo, additional, Duran-Silva, Mauricio, additional, Rodriguez, Bellanid, additional, Celis-Preciado, Carlos Andres, additional, Cano-Rosales, Diana Jimena, additional, Solarte, Ivan, additional, Fernandez- Sanchez, Maria Jose, additional, Parada-Tovar, Patricia, additional, von Bülow, Anna, additional, Bjerrum, Anne Sofie, additional, Ulrik, Charlotte S, additional, Assing, Karin Dahl, additional, Rasmussen, Linda Makowska, additional, Hansen, Susanne, additional, Altraja, Alan, additional, Bourdin, Arnaud, additional, Taille, Camille, additional, Charriot, Jeremy, additional, Roche, Nicolas, additional, Papaioannou, Andriana I, additional, Kostikas, Konstantinos, additional, Papadopoulos, Nikolaos G., additional, Salvi, Sundeep, additional, Long, Deirdre, additional, Mitchell, Patrick D, additional, Costello, Richard, additional, Sirena, Concetta, additional, Cardini, Cristina, additional, Heffler, Enrico, additional, Puggioni, Francesca, additional, Canonica, Giorgio Walter, additional, Guida, Giuseppe, additional, Iwanaga, Takashi, additional, Al-Ahmad, Mona, additional, García, Ulises, additional, Kuna, Piotr, additional, Fonseca, João A., additional, Al-Lehebi, Riyad, additional, Koh, Mariko S., additional, Rhee, Chin Kook, additional, Cosio, Borja G, additional, Perez de Llano, Luis, additional, Perng, Diahn-Warng, additional, Huang, Erick Wan-Chun, additional, Wang, Hao-Chien, additional, Tsai, Ming-Ju, additional, Mahboub, Bassam, additional, Salameh, Laila Ibraheem Jaber, additional, Jackson, David J., additional, Busby, John, additional, Heaney, Liam G, additional, Pfeffer, Paul E., additional, Goddard, Amanda Grippen, additional, Wang, Eileen, additional, Hoyte, Flavia C. L., additional, Chapman, Nicholas M, additional, Katial, Rohit, additional, Carter, Victoria, additional, Bulathsinhala, Lakmini, additional, Eleangovan, Neva, additional, Ariti, Con, additional, Lyu, Juntao, additional, Porsbjerg, Celeste, additional, and Price, David B., additional

Published
2023
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31. Impact of Undiagnosed COPD and Asthma on Symptoms, Quality of Life, Healthcare Utilization and Work Productivity

Author

Gerstein, Emily, primary, Bierbrier, Jared, additional, Whitmore, G A, additional, Vandemheen, Katherine L, additional, Bergeron, Celine, additional, Boulet, Louis-Philippe, additional, Cote, Andreanne, additional, Field, Stephen K, additional, Penz, Erika, additional, McIvor, R. Andrew, additional, Lemière, Catherine, additional, Gupta, Samir, additional, Hernandez, Paul, additional, Mayers, Irvin, additional, Bhutani, Mohit, additional, Lougheed, M. Diane, additional, Licskai, Christopher J., additional, Azher, Tanweer, additional, Ezer, Nicole, additional, Ainslie, Martha, additional, Alvarez, Gonzalo G., additional, Mulpuru, Sunita, additional, and Aaron, Shawn D, additional

Published
2023
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32. Identifying undiagnosed asthma in symptomatic adults with normal pre- and post-bronchodilator spirometry

Author

Shin, Sheojung, primary, Whitmore, George, additional, Boulet, Louis-Philippe, additional, Boulay, Marie-Ève, additional, Côté, Andréanne, additional, Bergeron, Céline, additional, Lemière, Catherine, additional, Lougheed, M. Diane, additional, Vandemheen, Katherine L, additional, Alvarez, Gonazlo, additional, Mulpuru, Sunita, additional, and Aaron, Shawn, additional

Published
2023
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33. Patient‐centered digital biomarkers for allergic respiratory diseases and asthma: The ARIA‐EAACI approach – ARIA‐EAACI Task Force Report

Author

Bousquet, Jean, primary, Shamji, Mohamed H., additional, Anto, Josep M., additional, Schünemann, Holger J., additional, Canonica, G. Walter, additional, Jutel, Marek, additional, Del Giacco, Stefano, additional, Zuberbier, Torsten, additional, Pfaar, Oliver, additional, Fonseca, Joao A., additional, Sousa‐Pinto, Bernardo, additional, Klimek, Ludger, additional, Czarlewski, Wienczyslawa, additional, Bedbrook, Anna, additional, Amaral, Rita, additional, Ansotegui, Ignacio J., additional, Bosnic‐Anticevich, Sinthia, additional, Braido, Fulvio, additional, Chaves Loureiro, Claudia, additional, Gemicioglu, Bilun, additional, Haahtela, Tari, additional, Kulus, Marek, additional, Kuna, Piotr, additional, Kupczyk, Maciej, additional, Matricardi, Paolo M., additional, Regateiro, Frederico S., additional, Samolinski, Boleslaw, additional, Sofiev, Mikhail, additional, Toppila‐Salmi, Sanna, additional, Valiulis, Arunas, additional, Ventura, Maria Teresa, additional, Barbara, Cristina, additional, Bergmann, Karl C., additional, Bewick, Michael, additional, Blain, Hubert, additional, Bonini, Matteo, additional, Boulet, Louis‐Philippe, additional, Bourret, Rodolphe, additional, Brusselle, Guy, additional, Brussino, Luisa, additional, Buhl, Roland, additional, Cardona, Victoria, additional, Casale, Thomas, additional, Cecchi, Lorenzo, additional, Charpin, Denis, additional, Cherrez‐Ojeda, Ivan, additional, Chu, Derek K., additional, Cingi, Cemal, additional, Costa, Elisio M., additional, Cruz, Alvaro A., additional, Devillier, Philippe, additional, Dramburg, Stephanie, additional, Fokkens, Wytske J., additional, Gotua, Maia, additional, Heffler, Enrico, additional, Ispayeva, Zhanat, additional, Ivancevich, Juan Carlos, additional, Joos, Guy, additional, Kaidashev, Igor, additional, Kraxner, Helga, additional, Kvedariene, Violeta, additional, Larenas‐Linnemann, Désirée E., additional, Laune, Daniel, additional, Lourenço, Olga, additional, Louis, Renaud, additional, Makela, Mika, additional, Makris, Michael, additional, Maurer, Marcus, additional, Melén, Erik, additional, Micheli, Yann, additional, Morais‐Almeida, Mario, additional, Mullol, Joaquim, additional, Niedoszytko, Marek, additional, O'Hehir, Robyn, additional, Okamoto, Yoshitaka, additional, Olze, Heidi, additional, Papadopoulos, Nikolaos G., additional, Papi, Alberto, additional, Patella, Vincenzo, additional, Pétré, Benoit, additional, Pham‐Thi, Nhân, additional, Puggioni, Francesca, additional, Quirce, Santiago, additional, Roche, Nicolas, additional, Rouadi, Philip W., additional, Sá‐Sousa, Ana, additional, Sagara, Hironori, additional, Sastre, Joaquin, additional, Scichilone, Nicola, additional, Sheikh, Aziz, additional, Sova, Milan, additional, Suppli Ulrik, Charlotte, additional, Taborda‐Barata, Luis, additional, Todo‐Bom, Ana, additional, Torres, Maria J., additional, Tsiligianni, Ioanna, additional, Usmani, Omar S., additional, Valovirta, Erkka, additional, Vasankari, Tuula, additional, Vieira, Rafael José, additional, Wallace, Dana, additional, Waserman, Susan, additional, Zidarn, Mihaela, additional, Yorgancioglu, Arzu, additional, Zhang, Luo, additional, Chivato, Tomas, additional, and Ollert, Markus, additional

Published
2023
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35. Impact of Undiagnosed Chronic Obstructive Pulmonary Disease and Asthma on Symptoms, Quality of Life, Healthcare Use, and Work Productivity.

Author

Gerstein, Emily, Bierbrier, Jared, Whitmore, G. Alex, Vandemheen, Katherine L., Bergeron, Celine, Boulet, Louis-Philippe, Cote, Andreanne, Field, Stephen K., Penz, Erika, McIvor, R. Andrew, Lemière, Catherine, Gupta, Samir, Hernandez, Paul, Mayers, Irvin, Bhutani, Mohit, Lougheed, M. Diane, Licskai, Christopher J., Azher, Tanweer, Ezer, Nicole, and Ainslie, Martha

Abstract

Rationale: A significant proportion of individuals with chronic obstructive pulmonary disease (COPD) and asthma remain undiagnosed. Objectives: The objective of this study was to evaluate symptoms, quality of life, healthcare use, and work productivity in subjects with undiagnosed COPD or asthma compared with those previously diagnosed, as well as healthy control subjects. Methods: This multicenter population-based case-finding study randomly recruited adults with respiratory symptoms who had no previous history of diagnosed lung disease from 17 Canadian centers using random digit dialing. Participants who exceeded symptom thresholds on the Asthma Screening Questionnaire or the COPD Diagnostic Questionnaire underwent pre- and post-bronchodilator spirometry to determine if they met diagnostic criteria for COPD or asthma. Two control groups, a healthy group without respiratory symptoms and a symptomatic group with previously diagnosed COPD or asthma, were similarly recruited. Measurements and Main Results: A total of 26,905 symptomatic individuals were interviewed, and 4,272 subjects were eligible. Of these, 2,857 completed pre- and post-bronchodilator spirometry, and 595 (21%) met diagnostic criteria for COPD or asthma. Individuals with undiagnosed COPD or asthma reported greater impact of symptoms on health status and daily activities, worse disease-specific and general quality of life, greater healthcare use, and poorer work productivity than healthy control subjects. Individuals with undiagnosed asthma had symptoms, quality of life, and healthcare use burden similar to those of individuals with previously diagnosed asthma, whereas subjects with undiagnosed COPD were less disabled than those with previously diagnosed COPD. Conclusions: Undiagnosed COPD or asthma imposes important, unmeasured burdens on the healthcare system and is associated with poor health status and negative effects on work productivity. [ABSTRACT FROM AUTHOR]

Published
2023
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36. Management of cough in Canadian primary care and specialty practices: A survey of current knowledge of clinicians and allied health professionals

Author

Boulet, Louis-Philippe, primary, Boulay, Marie-Ève, additional, Lecours, Laurent, additional, Kaplan, Alan, additional, Bourbeau, Jean, additional, Horvat, Emily, additional, Côté, Andréanne, additional, Field, Stephen K., additional, Gagné, Myriam, additional, Gupta, Samir, additional, Lépine, Pierre-Alexis, additional, and Satia, Imran, additional

Published
2023
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38. Not just an anti-eosinophil drug:tezepelumab treatment for type 2 asthma and beyond

Author

Corren, Jonathan, Brightling, Christopher E., Boulet, Louis Philippe, Porsbjerg, Celeste, Wechsler, Michael E., Menzies-Gow, Andrew, Ambrose, Christopher S., Cook, Bill, Martin, Neil, Spahn, Joseph, Llanos, Jean Pierre, Corren, Jonathan, Brightling, Christopher E., Boulet, Louis Philippe, Porsbjerg, Celeste, Wechsler, Michael E., Menzies-Gow, Andrew, Ambrose, Christopher S., Cook, Bill, Martin, Neil, Spahn, Joseph, and Llanos, Jean Pierre

Published
2023

39. Patient-centered digital biomarkers for allergic respiratory diseases and asthma:The ARIA-EAACI approach – ARIA-EAACI Task Force Report

Author

Bousquet, Jean, Shamji, Mohamed H., Anto, Josep M., Schünemann, Holger J., Canonica, G. Walter, Jutel, Marek, Del Giacco, Stefano, Zuberbier, Torsten, Pfaar, Oliver, Fonseca, Joao A., Sousa-Pinto, Bernardo, Klimek, Ludger, Czarlewski, Wienczyslawa, Bedbrook, Anna, Amaral, Rita, Ansotegui, Ignacio J., Bosnic-Anticevich, Sinthia, Braido, Fulvio, Chaves Loureiro, Claudia, Gemicioglu, Bilun, Haahtela, Tari, Kulus, Marek, Kuna, Piotr, Kupczyk, Maciej, Matricardi, Paolo M, Regateiro, Frederico S., Samolinski, Boleslaw, Sofiev, Mikhail, Toppila-Salmi, Sanna, Valiulis, Arunas, Ventura, Maria Teresa, Barbara, Cristina, Bergmann, Karl C., Bewick, Michael, Blain, Hubert, Bonini, Matteo, Boulet, Louis Philippe, Bourret, Rodolphe, Brusselle, Guy, Brussino, Luisa, Buhl, Roland, Cardona, Victoria, Casale, Thomas, Cecchi, Lorenzo, Charpin, Denis, Cherrez-Ojeda, Ivan, Chu, Derek K., Cingi, Cemal, Costa, Elisio M., Cruz, Alvaro A, Devillier, Philippe, Dramburg, Stephanie, Fokkens, Wytske J, Gotua, Maia, Heffler, Enrico, Ispayeva, Zhanat, Ivancevich, Juan Carlos, Joos, Guy, Kaidashev, Igor, Kraxner, Helga, Kvedariene, Violeta, Larenas-Linnemann, Désirée E., Laune, Daniel, Lourenço, Olga, Louis, Renaud, Makela, Mika, Makris, Michael, Maurer, Marcus, Melén, Erik, Micheli, Yann, Morais-Almeida, Mario, Mullol, Joaquim, Niedoszytko, Marek, O'Hehir, Robyn, Okamoto, Yoshitaka, Olze, Heidi, Papadopoulos, Nikolaos G., Papi, Alberto, Patella, Vincenzo, Pétré, Benoit, Pham-Thi, Nhân, Puggioni, Francesca, Quirce, Santiago, Roche, Nicolas, Rouadi, Philip W, Sá-Sousa, Ana, Sagara, Hironori, Sastre, Joaquin, Scichilone, Nicola, Sheikh, Aziz, Sova, Milan, Suppli Ulrik, Charlotte, Taborda-Barata, Luis, Todo-Bom, Ana, Torres, Maria J, Tsiligianni, Ioanna, Usmani, Omar S., Valovirta, Erkka, Vasankari, Tuula, Vieira, Rafael José, Wallace, Dana, Waserman, Susan, Zidarn, Mihaela, Yorgancioglu, Arzu, Zhang, Luo, Chivato, Tomas, Ollert, Markus, Bousquet, Jean, Shamji, Mohamed H., Anto, Josep M., Schünemann, Holger J., Canonica, G. Walter, Jutel, Marek, Del Giacco, Stefano, Zuberbier, Torsten, Pfaar, Oliver, Fonseca, Joao A., Sousa-Pinto, Bernardo, Klimek, Ludger, Czarlewski, Wienczyslawa, Bedbrook, Anna, Amaral, Rita, Ansotegui, Ignacio J., Bosnic-Anticevich, Sinthia, Braido, Fulvio, Chaves Loureiro, Claudia, Gemicioglu, Bilun, Haahtela, Tari, Kulus, Marek, Kuna, Piotr, Kupczyk, Maciej, Matricardi, Paolo M, Regateiro, Frederico S., Samolinski, Boleslaw, Sofiev, Mikhail, Toppila-Salmi, Sanna, Valiulis, Arunas, Ventura, Maria Teresa, Barbara, Cristina, Bergmann, Karl C., Bewick, Michael, Blain, Hubert, Bonini, Matteo, Boulet, Louis Philippe, Bourret, Rodolphe, Brusselle, Guy, Brussino, Luisa, Buhl, Roland, Cardona, Victoria, Casale, Thomas, Cecchi, Lorenzo, Charpin, Denis, Cherrez-Ojeda, Ivan, Chu, Derek K., Cingi, Cemal, Costa, Elisio M., Cruz, Alvaro A, Devillier, Philippe, Dramburg, Stephanie, Fokkens, Wytske J, Gotua, Maia, Heffler, Enrico, Ispayeva, Zhanat, Ivancevich, Juan Carlos, Joos, Guy, Kaidashev, Igor, Kraxner, Helga, Kvedariene, Violeta, Larenas-Linnemann, Désirée E., Laune, Daniel, Lourenço, Olga, Louis, Renaud, Makela, Mika, Makris, Michael, Maurer, Marcus, Melén, Erik, Micheli, Yann, Morais-Almeida, Mario, Mullol, Joaquim, Niedoszytko, Marek, O'Hehir, Robyn, Okamoto, Yoshitaka, Olze, Heidi, Papadopoulos, Nikolaos G., Papi, Alberto, Patella, Vincenzo, Pétré, Benoit, Pham-Thi, Nhân, Puggioni, Francesca, Quirce, Santiago, Roche, Nicolas, Rouadi, Philip W, Sá-Sousa, Ana, Sagara, Hironori, Sastre, Joaquin, Scichilone, Nicola, Sheikh, Aziz, Sova, Milan, Suppli Ulrik, Charlotte, Taborda-Barata, Luis, Todo-Bom, Ana, Torres, Maria J, Tsiligianni, Ioanna, Usmani, Omar S., Valovirta, Erkka, Vasankari, Tuula, Vieira, Rafael José, Wallace, Dana, Waserman, Susan, Zidarn, Mihaela, Yorgancioglu, Arzu, Zhang, Luo, Chivato, Tomas, and Ollert, Markus

Abstract

Biomarkers for the diagnosis, treatment and follow-up of patients with rhinitis and/or asthma are urgently needed. Although some biologic biomarkers exist in specialist care for asthma, they cannot be largely used in primary care. There are no validated biomarkers in rhinitis or allergen immunotherapy (AIT) that can be used in clinical practice. The digital transformation of health and health care (including mHealth) places the patient at the center of the health system and is likely to optimize the practice of allergy. Allergic Rhinitis and its Impact on Asthma (ARIA) and EAACI (European Academy of Allergy and Clinical Immunology) developed a Task Force aimed at proposing patient-reported outcome measures (PROMs) as digital biomarkers that can be easily used for different purposes in rhinitis and asthma. It first defined control digital biomarkers that should make a bridge between clinical practice, randomized controlled trials, observational real-life studies and allergen challenges. Using the MASK-air app as a model, a daily electronic combined symptom-medication score for allergic diseases (CSMS) or for asthma (e-DASTHMA), combined with a monthly control questionnaire, was embedded in a strategy similar to the diabetes approach for disease control. To mimic real-life, it secondly proposed quality-of-life digital biomarkers including daily EQ-5D visual analogue scales and the bi-weekly RhinAsthma Patient Perspective (RAAP). The potential implications for the management of allergic respiratory diseases were proposed., Biomarkers for the diagnosis, treatment and follow-up of patients with rhinitis and/or asthma are urgently needed. Although some biologic biomarkers exist in specialist care for asthma, they cannot be largely used in primary care. There are no validated biomarkers in rhinitis or allergen immunotherapy (AIT) that can be used in clinical practice. The digital transformation of health and health care (including mHealth) places the patient at the center of the health system and is likely to optimize the practice of allergy. Allergic Rhinitis and its Impact on Asthma (ARIA) and EAACI (European Academy of Allergy and Clinical Immunology) developed a Task Force aimed at proposing patient-reported outcome measures (PROMs) as digital biomarkers that can be easily used for different purposes in rhinitis and asthma. It first defined control digital biomarkers that should make a bridge between clinical practice, randomized controlled trials, observational real-life studies and allergen challenges. Using the MASK-air app as a model, a daily electronic combined symptom-medication score for allergic diseases (CSMS) or for asthma (e-DASTHMA), combined with a monthly control questionnaire, was embedded in a strategy similar to the diabetes approach for disease control. To mimic real-life, it secondly proposed quality-of-life digital biomarkers including daily EQ-5D visual analogue scales and the bi-weekly RhinAsthma Patient Perspective (RAAP). The potential implications for the management of allergic respiratory diseases were proposed.

Published
2023

40. Patient‐centred digital biomarkers for allergic respiratory diseases and asthma: the ARIA‐EAACI approach

Author

Bousquet, Jean, Shamji, Mohamed H., Anto, Josep M., Schünemann, Holger J., Canonica, G. Walter, Jutel, Marek, Del Giacco, Stefano, Zuberbier, Torsten, Pfaar, Oliver, Fonseca, Joao A., Sousa‐Pinto, Bernardo, Klimek, Ludger, Czarlewski, Wienczyslawa, Bedbrook, Anna, Amaral, Rita, Ansotegui, Ignacio J., Bosnic‐Anticevich, Sinthia, Braido, Fulvio, Loureiro, Claudia Chaves, Gemicioglu, Bilun, Haahtela, Tari, Kulus, Marek, Kuna, Piotr, Kupczyk, Maciej, Matricardi, Paolo M., Regateiro, Frederico S., Samolinski, Boleslaw, Sofiev, Mikhail, Toppila‐Salmi, Sanna, Valiulis, Arunas, Ventura, Maria Teresa, Barbara, Cristina, Bergmann, Karl C., Bewick, Michael, Blain, Hubert, Bonini, Matteo, Boulet, Louis‐Philippe, Bourret, Rodolphe, Brusselle, Guy, Brussino, Luisa, Buhl, Roland, Cardona, Victoria, Casale, Thomas, Cecchi, Lorenzo, Charpin, Denis, Cherrez‐Ojeda, Ivan, Chu, Derek K., Cingi, Cemal, Costa, Elisio M., Cruz, Alvaro A., Devillier, Philippe, Dramburg, Stephanie, Fokkens, Wytske J., Gotua, Maia, Heffler, Enrico, Ispayeva, Zhanat, Ivancevich, Juan Carlos, Joos, Guy, Kaidashev, Igor, Kraxner, Helga, Kvedariene, Violeta, Larenas‐Linnemann, Désirée E., Laune, Daniel, Lourenço, Olga, Louis, Renaud, Makela, Mika, Makris, Michael, Maurer, Marcus, Melén, Erik, Micheli, Yann, Morais‐Almeida, Mario, Mullol, Joaquim, Niedoszytko, Marek, O’Hehir, Robyn, Okamoto, Yoshitaka, Olze, Heidi, Papadopoulos, Nikolaos G., Papi, Alberto, Patella, Vincenzo, Pétré, Benoit, Pham‐Thi, Nhân, Puggioni, Francesca, Quirce, Santiago, Roche, Nicolas, Rouadi, Philip W., Sá‐Sousa, Ana, Sagara, Hironori, Sastre, Joaquin, Scichilone, Nicola, Sheikh, Aziz, Sova, Milan, Ulrik, Charlotte Suppli, Taborda‐Barata, Luis, Todo‐Bom, Ana, Torres, Maria J., Tsiligianni, Ioanna, Usmani, Omar S., Valovirta, Erkka, Vasankari, Tuula, Vieira, Rafael José, Wallace, Dana, Waserman, Susan, Zidarn, Mihaela, Yorgancioglu, Arzu, Zhang, Luo, Chivato, Tomas, Ollert, Markus, Bousquet, Jean, Shamji, Mohamed H., Anto, Josep M., Schünemann, Holger J., Canonica, G. Walter, Jutel, Marek, Del Giacco, Stefano, Zuberbier, Torsten, Pfaar, Oliver, Fonseca, Joao A., Sousa‐Pinto, Bernardo, Klimek, Ludger, Czarlewski, Wienczyslawa, Bedbrook, Anna, Amaral, Rita, Ansotegui, Ignacio J., Bosnic‐Anticevich, Sinthia, Braido, Fulvio, Loureiro, Claudia Chaves, Gemicioglu, Bilun, Haahtela, Tari, Kulus, Marek, Kuna, Piotr, Kupczyk, Maciej, Matricardi, Paolo M., Regateiro, Frederico S., Samolinski, Boleslaw, Sofiev, Mikhail, Toppila‐Salmi, Sanna, Valiulis, Arunas, Ventura, Maria Teresa, Barbara, Cristina, Bergmann, Karl C., Bewick, Michael, Blain, Hubert, Bonini, Matteo, Boulet, Louis‐Philippe, Bourret, Rodolphe, Brusselle, Guy, Brussino, Luisa, Buhl, Roland, Cardona, Victoria, Casale, Thomas, Cecchi, Lorenzo, Charpin, Denis, Cherrez‐Ojeda, Ivan, Chu, Derek K., Cingi, Cemal, Costa, Elisio M., Cruz, Alvaro A., Devillier, Philippe, Dramburg, Stephanie, Fokkens, Wytske J., Gotua, Maia, Heffler, Enrico, Ispayeva, Zhanat, Ivancevich, Juan Carlos, Joos, Guy, Kaidashev, Igor, Kraxner, Helga, Kvedariene, Violeta, Larenas‐Linnemann, Désirée E., Laune, Daniel, Lourenço, Olga, Louis, Renaud, Makela, Mika, Makris, Michael, Maurer, Marcus, Melén, Erik, Micheli, Yann, Morais‐Almeida, Mario, Mullol, Joaquim, Niedoszytko, Marek, O’Hehir, Robyn, Okamoto, Yoshitaka, Olze, Heidi, Papadopoulos, Nikolaos G., Papi, Alberto, Patella, Vincenzo, Pétré, Benoit, Pham‐Thi, Nhân, Puggioni, Francesca, Quirce, Santiago, Roche, Nicolas, Rouadi, Philip W., Sá‐Sousa, Ana, Sagara, Hironori, Sastre, Joaquin, Scichilone, Nicola, Sheikh, Aziz, Sova, Milan, Ulrik, Charlotte Suppli, Taborda‐Barata, Luis, Todo‐Bom, Ana, Torres, Maria J., Tsiligianni, Ioanna, Usmani, Omar S., Valovirta, Erkka, Vasankari, Tuula, Vieira, Rafael José, Wallace, Dana, Waserman, Susan, Zidarn, Mihaela, Yorgancioglu, Arzu, Zhang, Luo, Chivato, Tomas, and Ollert, Markus

Abstract

Biomarkers for the diagnosis, treatment and follow-up of patients with rhinitis and/or asthma are urgently needed. Although some biologic biomarkers exist in specialist care for asthma, they cannot be largely used in primary care. There are no validated biomarkers in rhinitis or allergen immunotherapy (AIT) that can be used in clinical practice. The digital transformation of health and health care (including mHealth) places the patient at the centre of the health system and is likely to optimise the practice of allergy. ARIA (Allergic Rhinitis and its Impact on Asthma) and EAACI (European Academy of Allergy and Clinical Immunology) developed a Task Force aimed at proposing patient-reported outcome measures (PROMs) as digital biomarkers that can be easily used for different purposes in rhinitis and asthma. It first defined control digital biomarkers that should make a bridge between clinical practice, randomised controlled trials, observational real-life studies and allergen challenges. Using the MASK-air app as a model, a daily electronic combined symptom-medication score for allergic diseases (CSMS) or for asthma (e-DASTHMA), combined with a monthly control questionnaire, were embedded in a strategy similar to the diabetes approach for disease control. To mimic real-life, it secondly proposed quality-of-life digital biomarkers including daily EQ-5D visual analogue scales and the bi-weekly RhinAsthma Patient Perspective (RAAP). The potential implications for the management of allergic respiratory diseases were proposed.

Published
2023
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41. Development and validation of an electronic daily control score for asthma (e-DASTHMA):a real-world direct patient data study

Author

Sousa-Pinto, Bernardo, Jácome, Cristina, Pereira, Ana Margarida, Regateiro, Frederico S., Almeida, Rute, Czarlewski, Wienczyslawa, Kulus, Marek, Shamji, Mohamed H., Boulet, Louis-Philippe, Bonini, Matteo, Brussino, Luisa, Canonica, G. Walter, Cruz, Alvaro A., Gemicioglu, Bilun, Haahtela, Tari, Kupczyk, Maciej, Kvedariene, Violeta, Larenas-Linnemann, Desirée, Louis, Renaud, Niedoszytko, Marek, Pham-Thi, Nhân, Puggioni, Francesca, Romantowski, Jan, Sastre, Joaquin, Scichilone, Nicola, Taborda-Barata, Luis, Ventura, Maria Teresa, Vieira, Rafael José, Agache, Ioana, Bedbrook, Anna, Bergmann, Karl C., Amaral, Rita, Azevedo, Luís Filipe, Bosnic-Anticevich, Sinthia, Brusselle, Guy, Buhl, Roland, Cecchi, Lorenzo, Charpin, Denis, Loureiro, Claudia Chaves, de Blay, Frédéric, Del Giacco, Stefano, Devillier, Philippe, Jassem, Ewa, Joos, Guy, Jutel, Marek, Klimek, Ludger, Kuna, Piotr, Laune, Daniel, Pech, Jorge Luna, Makela, Mika, Morais-Almeida, Mario, Nadif, Rachel, Neffen, Hugo E., Ohta, Ken, Papadopoulos, Nikolaos G., Papi, Alberto, Pétré, Benoit, Pfaar, Oliver, Yeverino, Daniela Rivero, Cordeiro, Carlos Robalo, Roche, Nicolas, Sá-Sousa, Ana, Samolinski, Boleslaw, Sheikh, Aziz, Ulrik, Charlotte Suppli, Usmani, Omar S., Valiulis, Arunas, Vandenplas, Olivier, Vieira-Marques, Pedro, Yorgancioglu, Arzu, Zuberbier, Torsten, Anto, Josep M., Fonseca, João A., Bousquet, Jean, Sousa-Pinto, Bernardo, Jácome, Cristina, Pereira, Ana Margarida, Regateiro, Frederico S., Almeida, Rute, Czarlewski, Wienczyslawa, Kulus, Marek, Shamji, Mohamed H., Boulet, Louis-Philippe, Bonini, Matteo, Brussino, Luisa, Canonica, G. Walter, Cruz, Alvaro A., Gemicioglu, Bilun, Haahtela, Tari, Kupczyk, Maciej, Kvedariene, Violeta, Larenas-Linnemann, Desirée, Louis, Renaud, Niedoszytko, Marek, Pham-Thi, Nhân, Puggioni, Francesca, Romantowski, Jan, Sastre, Joaquin, Scichilone, Nicola, Taborda-Barata, Luis, Ventura, Maria Teresa, Vieira, Rafael José, Agache, Ioana, Bedbrook, Anna, Bergmann, Karl C., Amaral, Rita, Azevedo, Luís Filipe, Bosnic-Anticevich, Sinthia, Brusselle, Guy, Buhl, Roland, Cecchi, Lorenzo, Charpin, Denis, Loureiro, Claudia Chaves, de Blay, Frédéric, Del Giacco, Stefano, Devillier, Philippe, Jassem, Ewa, Joos, Guy, Jutel, Marek, Klimek, Ludger, Kuna, Piotr, Laune, Daniel, Pech, Jorge Luna, Makela, Mika, Morais-Almeida, Mario, Nadif, Rachel, Neffen, Hugo E., Ohta, Ken, Papadopoulos, Nikolaos G., Papi, Alberto, Pétré, Benoit, Pfaar, Oliver, Yeverino, Daniela Rivero, Cordeiro, Carlos Robalo, Roche, Nicolas, Sá-Sousa, Ana, Samolinski, Boleslaw, Sheikh, Aziz, Ulrik, Charlotte Suppli, Usmani, Omar S., Valiulis, Arunas, Vandenplas, Olivier, Vieira-Marques, Pedro, Yorgancioglu, Arzu, Zuberbier, Torsten, Anto, Josep M., Fonseca, João A., and Bousquet, Jean

Abstract

Background: Validated questionnaires are used to assess asthma control over the past 1–4 weeks from reporting. However, they do not adequately capture asthma control in patients with fluctuating symptoms. Using the Mobile Airways Sentinel Network for airway diseases (MASK-air) app, we developed and validated an electronic daily asthma control score (e-DASTHMA). Methods: We used MASK-air data (freely available to users in 27 countries) to develop and assess different daily control scores for asthma. Data-driven control scores were developed based on asthma symptoms reported by a visual analogue scale (VAS) and self-reported asthma medication use. We included the daily monitoring data from all MASK-air users aged 16–90 years (or older than 13 years to 90 years in countries with a lower age of digital consent) who had used the app in at least 3 different calendar months and had reported at least 1 day of asthma medication use. For each score, we assessed construct validity, test–retest reliability, responsiveness, and accuracy. We used VASs on dyspnoea and work disturbance, EQ-5D-VAS, Control of Allergic Rhinitis and Asthma Test (CARAT), CARAT asthma, and Work Productivity and Activity Impairment: Allergy Specific (WPAI:AS) questionnaires as comparators. We performed an internal validation using MASK-air data from Jan 1 to Oct 12, 2022, and an external validation using a cohort of patients with physician-diagnosed asthma (the INSPIRERS cohort) who had had their diagnosis and control (Global Initiative for Asthma [GINA] classification) of asthma ascertained by a physician. Findings: We studied 135 635 days of MASK-air data from 1662 users from May 21, 2015, to Dec 31, 2021. The scores were strongly correlated with VAS dyspnoea (Spearman correlation coefficient range 0·68–0·82) and moderately correlated with work comparators and quality-of-life-related comparators (for WPAI:AS work, we observed Spearman correlation coefficients of 0·59–0·68). They also displayed high

Published
2023

42. Inhaled anti-TSLP antibody fragment, ecleralimab, blocks responses to allergen in mild asthma

Author

Gauvreau, Gail M, primary, Hohlfeld, Jens M, additional, FitzGerald, Mark J, additional, Boulet, Louis-Philippe, additional, Cockcroft, Donald W, additional, Davis, Beth E, additional, Korn, Stephanie, additional, Kornmann, Oliver, additional, Leigh, Richard, additional, Mayers, Irvin, additional, Watz, Henrik, additional, Grant, Sarah S, additional, Jain, Monish, additional, Cabanseki, Maciej, additional, Pertel, Peter E, additional, Jones, Ieuan, additional, Lecot, Jean R, additional, Cao, Hui, additional, and O'Byrne, Paul M, additional

Published
2023
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45. Burden of Pertussis in Individuals with a Diagnosis of Asthma: A Retrospective Database Study in England

Author

Bhavsar, Amit, Aris, Emmanuel, Harrington, Lauriane, Simeone, Jason C, Ramond, Anna, Lambrelli, Dimitra, Papi, Alberto, Boulet, Louis-Philippe, Meszaros, Kinga, Jamet, Nicolas, Sergerie, Yan, and Mukherjee, Piyali

Subjects
Pulmonary and Respiratory Medicine, health care resource utilization, pertussis, Journal of Asthma and Allergy, incidence, Socio-culturale, Immunology and Allergy, direct medical costs, Asthma, direct medical costs, health care resource utilization, incidence, pertussis, asthma, respiratory tract diseases, Original Research
Abstract

Amit Bhavsar,1 Emmanuel Aris,2 Lauriane Harrington,3 Jason C Simeone,4 Anna Ramond,5 Dimitra Lambrelli,5 Alberto Papi,6 Louis-Philippe Boulet,7 Kinga Meszaros,8 Nicolas Jamet,8 Yan Sergerie,3 Piyali Mukherjee3 1Europe Medical Affairs, GSK, Wavre, Belgium; 2Real-World Analytics, GSK, Wavre, Belgium; 3Global Medical Affairs, GSK, Wavre, Belgium; 4Real-World Evidence, Evidera Inc., Waltham, MA, USA; 5Real-World Evidence, Evidera Ltd, London, UK; 6Respiratory Medicine, University of Ferrara, Ferrara, Italy; 7Department of Medicine, Laval University, Quebec City, Quebec, Canada; 8Value Evidence and Outcomes, GSK, Wavre, BelgiumCorrespondence: Amit Bhavsar Tel +32 10 85 51 11Email amit.b.bhavsar@gsk.comPurpose: The impact of pertussis in individuals with asthma is not fully understood. We estimated the incidence, health care resource utilization (HCRU), and direct medical costs (DMC) of pertussis in patients with asthma.Patients and Methods: In this retrospective cohort study, the incidence rate of pertussis (identified using diagnostic codes) among individuals aged ≥ 50 years with an asthma diagnosis was assessed during 2009– 2018 using Clinical Practice Research Datalink and Hospital Episode Statistics databases. HCRU and DMC were compared – between patients with diagnoses of asthma and pertussis (asthma+/pertussis+) and propensity score-matched patients with a diagnosis of asthma without pertussis (asthma+/pertussis–) – in the months around the pertussis diagnosis (– 6 to +11).Results: Among 687,105 individuals, 346 had a reported pertussis event (incidence rate: 9.6/100,000 person-years of follow-up; 95% confidence interval: 8.6– 10.7). HCRU and DMC were assessed among 314 asthma+/pertussis+ patients and 1256 matched asthma+/pertussis– controls. Baseline HCRU was similar in both cohorts, but increases were observed in the asthma+/pertussis+ cohort from – 6 to – 1 month before to 2– 5 months after diagnosis. Rates of accident and emergency visits, general practitioner (GP)/nurse visits, and GP prescriptions were 4.3-, 3.1-, and 1.3-fold, respectively, in the asthma+/pertussis+ vs asthma+/pertussis– cohorts during the month before diagnosis; GP/nurse visit rates were 2.0- and 1.2-fold during 0– 2 and 2– 5 months after diagnosis, respectively (all p< 0.001). DMC was 1.9- and 1.6-fold during the month before and 2 months from diagnosis, respectively, in the asthma+/pertussis+ vs asthma+/pertussis– cohorts (both p< 0.001). During months – 1 to +11, DMC in the asthma+/pertussis+ cohort was £ 370 higher than in the asthma+/pertussis– controls.Conclusion: A pertussis diagnosis among adults aged ≥ 50 years with asthma resulted in significant increases in HCRU and DMC across several months around diagnosis, suggesting lengthy diagnosis times and highlighting the need for prevention strategies.Keywords: asthma, direct medical costs, health care resource utilization, incidence, pertussis

Published
2022

46. Sounding the alarmins—The role of alarmin cytokines in asthma

Author

Gauvreau, Gail M., primary, Bergeron, Celine, additional, Boulet, Louis‐Philippe, additional, Cockcroft, Donald W., additional, Côté, Andréanne, additional, Davis, Beth E., additional, Leigh, Richard, additional, Myers, Irvin, additional, O'Byrne, Paul M., additional, and Sehmi, Roma, additional

Published
2022
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47. Criteria to evaluate efficacy of biologics in asthma: a Global Asthma Association survey

Author

Tiotiu, Angelica, primary, Bikov, Andras, additional, Gonzalez-Barcala, Francisco-Javier, additional, Novakova, Silviya, additional, Novakova, Plamena, additional, Chong-Neto, Herberto, additional, Santus, Pierachille, additional, Ansotegui, Ignacio J, additional, Ivancevich, Juan Carlos, additional, Kowal, Krzysztof, additional, Mihaicuta, Stefan, additional, Nedeva, Denislava, additional, Canonica, Giorgio Walter, additional, Bernstein, Jonathan, additional, Boulet, Louis-Philippe, additional, and Braido, Fulvio, additional

Published
2022
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50. Patient and physician factors associated with symptomatic undiagnosed asthma or COPD

Author

Cherian, Mathew, primary, Magner, Kate M. A., additional, Whitmore, G. A., additional, Vandemheen, Katherine L., additional, FitzGerald, J. Mark, additional, Bergeron, Celine, additional, Boulet, Louis-Philippe, additional, Cote, Andreanne, additional, Field, Stephen K., additional, Penz, Erika, additional, McIvor, R. Andrew, additional, Lemière, Catherine, additional, Gupta, Samir, additional, Mayers, Irvin, additional, Bhutani, Mohit, additional, Hernandez, Paul, additional, Lougheed, M. Diane, additional, Licskai, Christopher J., additional, Azher, Tanweer, additional, Ainslie, Martha, additional, Ezer, Nicole, additional, Mulpuru, Sunita, additional, and Aaron, Shawn D., additional

Published
2022
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