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119 results on '"Borrelli, Osvaldo"'

1. Multi-disciplinary Insights from the First European Forum on Visceral Myopathy 2022 Meeting

Author

Viti, Federica, De Giorgio, Roberto, Ceccherini, Isabella, Ahluwalia, Arti, Alves, Maria M., Baldo, Chiara, Baldussi, Giannina, Bonora, Elena, Borrelli, Osvaldo, Dall’Oglio, Luigi, De Coppi, Paolo, De Filippo, Carlotta, de Santa Barbara, Pascal, Diamanti, Antonella, Di Lorenzo, Carlo, Di Maulo, Ruggero, Galeone, Antonio, Gandullia, Paolo, Hashmi, Sohaib K., Lacaille, Florence, Lancon, Laurence, Leone, Salvatore, Mahé, Maxime M., Molnar, Maria Judit, Palmitelli, Alessandro, Perin, Silvia, Prato, Alessio Pini, Thapar, Nikhil, Vassalli, Massimo, and Heuckeroth, Robert O.

Published
2023
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4. Antroduodenal Manometry

Author

Rybak, Anna, Saliakellis, Efstratios, Thapar, Nikhil, Borrelli, Osvaldo, Faure, Christophe, editor, Thapar, Nikhil, editor, and Di Lorenzo, Carlo, editor

Published
2022
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7. Esophageal Achalasia

Author

Saliakellis, Efstratios, Rybak, Anna, Borrelli, Osvaldo, Guandalini, Stefano, editor, and Dhawan, Anil, editor

Published
2022
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8. Cyclic vomiting syndrome in children: a nationwide survey of current practice on behalf of the Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition (SIGENP) and Italian Society of Pediatric Neurology (SINP)

Author

Isoldi, Sara, Di Nardo, Giovanni, Mallardo, Saverio, Parisi, Pasquale, Raucci, Umberto, Tambucci, Renato, Quitadamo, Paolo, Salvatore, Silvia, Felici, Enrico, Cisarò, Fabio, Pensabene, Licia, Banzato, Claudia, Strisciuglio, Caterina, Romano, Claudio, Fusco, Patrizia, Rigotti, Francesca, Sansotta, Naire, Caimmi, Silvia, Savasta, Salvatore, Zuin, Giovanna, Di Stefano, Marina, Provera, Silvia, Campanozzi, Angelo, Rossi, Paolo, Gatti, Simona, Corpino, Mara, Alvisi, Patrizia, Martelossi, Stefano, Suppiej, Agnese, Gandullia, Paolo, Verrotti, Alberto, Terrin, Gianluca, Pacenza, Caterina, Fornaroli, Fabiola, Comito, Donatella, D’Arrigo, Stefano, Striano, Pasquale, Raviglione, Federico, Carotenuto, Marco, Orsini, Alessandro, Belcastro, Vincenzo, Di Corcia, Giovanna, Raieli, Vincenzo, Ferilli, Michela Ada Noris, Ruscitto, Claudia, Spadoni, Elisabetta, Grosso, Salvatore, D’Alonzo, Renato, Papa, Amanda, Pavone, Piero, Meli, Mariaclaudia, Velardita, Mario, Mainetti, Martina, Vanacore, Nicola, and Borrelli, Osvaldo

Published
2022
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10. Nutritional Management of Pediatric Gastrointestinal Motility Disorders.

Author

Jackman, Lucy, Arpe, Lauren, Thapar, Nikhil, Rybak, Anna, and Borrelli, Osvaldo

Abstract

Normal and optimal functioning of the gastrointestinal tract is paramount to ensure optimal nutrition through digestion, absorption and motility function. Disruptions in these functions can lead to adverse physiological symptoms, reduced quality of life and increased nutritional risk. When disruption or dysfunction of neuromuscular function occurs, motility disorders can be classified depending on whether coordination or strength/velocity of peristalsis are predominantly impacted. However, due to their nonspecific presenting symptoms and overlap with sensory disruption, they are frequently misdiagnosed as disorders of the gut–brain interaction. Motility disorders are a prevalent issue in the pediatric population, with management varying from medical therapy to psychological therapy, dietary manipulation, surgical intervention or a multimodal approach. This narrative review aims to discuss the dietary management of common pediatric motility disorders including gastroesophageal reflux, esophageal atresia, achalasia, gastroparesis, constipation, and the less common but most severe motility disorder, pediatric intestinal pseudo-obstruction. [ABSTRACT FROM AUTHOR]

Published
2024
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12. Italian guidelines for the management of irritable bowel syndrome in children and adolescents

Author

Di Nardo, Giovanni, primary, Barbara, Giovanni, additional, Borrelli, Osvaldo, additional, Cremon, Cesare, additional, Giorgio, Valentina, additional, Greco, Luigi, additional, La Pietra, Michele, additional, Marasco, Giovanni, additional, Pensabene, Licia, additional, Piccirillo, Marisa, additional, Romano, Claudio, additional, Salvatore, Silvia, additional, Saviano, Michele, additional, Stanghellini, Vincenzo, additional, Strisciuglio, Caterina, additional, Tambucci, Renato, additional, Turco, Rossella, additional, Zenzeri, Letizia, additional, and Staiano, Annamaria, additional

Published
2024
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13. Hypnotherapy in Pediatric Gastroenterology

Author

Vlieger, Arine M., Assa, Amit, Borrelli, Osvaldo, Broekaert, Ilse, Deganello Saccomani, Marco, Dolinsek, Jernej, Carpi de, Javier-Martin, Mas, Emmanuel, Miele, Erasmo, Thomson, Mike, Tzivinikos, Christos, and Benninga, Marc A.

Published
2023
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16. ESPGHAN and NASPGHAN 2023 protocol for paediatric FAPD treatment guidelines (standard operating procedure)

Author

Gordon, Morris, primary, Benninga, Marc A, additional, Borlack, Rachel, additional, Borrelli, Osvaldo, additional, Chogle, Ashish, additional, Darbari, Anil, additional, Dolinsek, Jernej, additional, Groen, Jip, additional, Khlevner, Julie, additional, Di Lorenzo, Carlo, additional, Person, Hannibal, additional, Saps, Miguel, additional, Sinopoulou, Vassiliki, additional, Snyder, Julie, additional, Tabbers, Merit, additional, Thapar, Nikhil, additional, and Vlieger, Arine, additional

Published
2023
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23. Recent advances in the treatment of gastrointestinal motility disorders in children.

Author

Nita, Andreia Florina, Chanpong, Atchariya, Nikaki, Kornilia, Rybak, Anna, Thapar, Nikhil, and Borrelli, Osvaldo

Subjects
GASTROINTESTINAL motility disorders, FECAL microbiota transplantation, GASTROPARESIS, ESOPHAGEAL atresia, ESOPHAGEAL achalasia
Abstract

Pediatric gastrointestinal motility disorders represent some of the most challenging clinical conditions with largely undefined pathogenetic pathways and therefore limited therapeutic options. Herein, we provide an overview of the recent advances in treatment options for these disorders and their clinical impact. PubMed and Medline databases were searched for relevant articles related to the treatment of achalasia, esophageal atresia, gastroparesis, PIPO and constipation published between 2017 and 2022. In this article, we review and summarize recent advances in management of gastrointestinal motility disorders in children with a particular focus on emerging therapies as well as novel diagnostic modalities that help guide their application or develop new, more targeted treatments. Gastrointestinal motility disorders represent one of the most challenging conundrums in pediatric age and despite significant advances in investigative tools, the palette of treatment options remain limited. Overall, while pharmacological options have failed to bring a curative solution, recent advances in minimal invasive therapeutic and diagnostic techniques have emerged as potential keys to symptom and quality of life improvement, such as ENDOFLIP, POEM, cine-MRI, fecal microbiota transplantation. [ABSTRACT FROM AUTHOR]

Published
2023
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24. Pediatric Magnet Ingestion, Diagnosis, Management, and Prevention: A European Society for Paediatric Gastroenterology Hepatology and Nutrition (ESPGHAN) Position Paper

Author

Nugud, A A, Tzivinikos, Christos, Assa, Amit, Borrelli, Osvaldo, Broekaert, Ilse, Martin-de-Carpi, Javier, Deganello Saccomani, Marco, Dolinsek, Jernej, Homan, M, Mas, Emmanuel, Miele, Erasmo, Thomson, Mike, Benninga, Marc A, Nugud, A A, Tzivinikos, Christo, Assa, Amit, Borrelli, Osvaldo, Broekaert, Ilse, Martin-de-Carpi, Javier, Deganello Saccomani, Marco, Dolinsek, Jernej, Homan, M, Mas, Emmanuel, Miele, Erasmo, Thomson, Mike, and Benninga, Marc A

Abstract

Magnet ingestion is a special category of foreign body ingestion associated with high levels of morbidity and mortality worldwide, particularly if it is associated with staggered ingestion of multiple magnets or with simultaneous ingestion of other metallic foreign bodies, especially button batteries. A special category of magnet ingestion is the ingestion of earth magnets, which have higher levels of magnetism and therefore, potentially, carries a worse outcome. Legislative bodies, scientific Societies and community-led initiatives have been implemented worldwide with the aim of mitigating the effects of this growing, yet avoidable potential medical emergency. A scoping literature review summarized epidemiology, diagnosis, management, and prevention, including an algorithm for the diagnosis and management of magnet ingestion is presented and compared to previously published reviews and position papers (North American Society of Pediatric Gastroenterology, Hepatology and Nutrition, National Poison Center, Royal College of Emergency Medicine). The main emphasis of the algorithm is on identification of staggered/multiple magnet ingestion, and early joint gastroenterology and surgical consultation and management.

Published
2023

25. European guideline on indications, performance, and clinical impact of hydrogen and methane breath tests in adult and pediatric patients: European Association for Gastroenterology, Endoscopy and Nutrition, European Society of Neurogastroenterology and Motility, and European Society for Paediatric Gastroenterology Hepatology and Nutrition consensus

Author

Hammer, Heinz F; https://orcid.org/0000-0001-8683-4951, Fox, Mark R; https://orcid.org/0000-0003-4394-5584, Keller, Jutta; https://orcid.org/0000-0002-5884-1115, Salvatore, Silvia, Basilisco, Guido, Hammer, Johann; https://orcid.org/0000-0002-2452-1201, Lopetuso, Loris, Benninga, Marc, Borrelli, Osvaldo, Dumitrascu, Dan, Hauser, Bruno, Herszenyi, Laszlo, Nakov, Radislav, Pohl, Daniel, Thapar, Nikhil, Sonyi, Marc, Hammer, Heinz F; https://orcid.org/0000-0001-8683-4951, Fox, Mark R; https://orcid.org/0000-0003-4394-5584, Keller, Jutta; https://orcid.org/0000-0002-5884-1115, Salvatore, Silvia, Basilisco, Guido, Hammer, Johann; https://orcid.org/0000-0002-2452-1201, Lopetuso, Loris, Benninga, Marc, Borrelli, Osvaldo, Dumitrascu, Dan, Hauser, Bruno, Herszenyi, Laszlo, Nakov, Radislav, Pohl, Daniel, Thapar, Nikhil, and Sonyi, Marc

Abstract

Introduction: Measurement of breath hydrogen (H2 ) and methane (CH4 ) excretion after ingestion of test-carbohydrates is used for different diagnostic purposes. There is a lack of standardization among centers performing these tests and this, together with recent technical developments and evidence from clinical studies, highlight the need for a European guideline. Methods: This consensus-based clinical practice guideline defines the clinical indications, performance, and interpretation of H2 -CH4 -breath tests in adult and pediatric patients. A balance between scientific evidence and clinical experience was achieved by a Delphi consensus that involved 44 experts from 18 European countries. Eighty eight statements and recommendations were drafted based on a review of the literature. Consensus (≥80% agreement) was reached for 82. Quality of evidence was evaluated using validated criteria. Results: The guideline incorporates new insights into the role of symptom assessment to diagnose carbohydrate (e.g., lactose) intolerances and recommends that breath tests for carbohydrate malabsorption require additional validated concurrent symptom evaluation to establish carbohydrate intolerance. Regarding the use of breath tests for the evaluation of oro-cecal transit time and suspected small bowel bacterial overgrowth, this guideline highlights confounding factors associated with the interpretation of H2 -CH4 -breath tests in these indications and recommends approaches to mitigate these issues. Conclusion: This clinical practice guideline should facilitate pan-European harmonization of diagnostic approaches to symptoms and disorders, which are very common in specialist and primary care gastroenterology practice, both in adult and pediatric patients. In addition, it identifies areas of future research needs to clarify diagnostic and therapeutic approaches. Keywords: fructose; intolerance; lactose; malabsorption; oro-cecal transit time; small intestinal bacterial overgrowth.

Published
2022

26. Drugs in focus: Domperidone

Author

Puoti, Maria Giovanna, primary, Assa, Amit, additional, Benninga, Marc, additional, Broekaert, Ilse Julia, additional, Carpi, Francisco Javier Martin, additional, Saccomani, Marco Deganello, additional, Dolinsek, Jernej, additional, Homan, Matjaz, additional, Mas, Emmanuel, additional, Miele, Erasmo, additional, Tzivinikos, Christos, additional, Tompson, Mike, additional, and Borrelli, Osvaldo, additional

Published
2023
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27. Prevalence of Non-erosive Esophageal Phenotypes in Children: A European Multicenter Study

Author

Blasi, Elisa, primary, Stefanelli, Ettore, additional, Tambucci, Renato, additional, Salvatore, Silvia, additional, Angelis, Paola De, additional, Quitadamo, Paolo, additional, Pacchiarotti, Claudia, additional, Nardo, Giovanni Di, additional, Crocco, Fanj, additional, Felici, Enrico, additional, Giorgio, Valentina, additional, Staropoli, Nicoletta, additional, Sestito, Simona, additional, Saliakellis, Efstratios, additional, Borrelli, Osvaldo, additional, and Pensabene, Licia, additional

Published
2023
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29. ESPGHAN and NASPGHAN 2023 protocol for paediatric FAPD treatment guidelines (standard operating procedure)

Author

Gordon, Morris, Benninga, Marc A, Borlack, Rachel, Borrelli, Osvaldo, Chogle, Ashish, Darbari, Anil, Dolinsek, Jernej, Groen, Jip, Khlevner, Julie, Di Lorenzo, Carlo, Person, Hannibal, Saps, Miguel, Sinopoulou, Vassiliki, Snyder, Julie, Tabbers, Merit, Thapar, Nikhil, Vlieger, Arine, Gordon, Morris, Benninga, Marc A, Borlack, Rachel, Borrelli, Osvaldo, Chogle, Ashish, Darbari, Anil, Dolinsek, Jernej, Groen, Jip, Khlevner, Julie, Di Lorenzo, Carlo, Person, Hannibal, Saps, Miguel, Sinopoulou, Vassiliki, Snyder, Julie, Tabbers, Merit, Thapar, Nikhil, and Vlieger, Arine

Abstract

Introduction To date, no international guidelines have been published for the treatment of paediatric functional abdominal pain disorders (FAPDs), subcategorised into functional abdominal pain–not otherwise specified (FAP-NOS), irritable bowel syndrome (IBS), functional dyspepsia and abdominal migraine (AM). We aim for a treatment guideline, focusing on FAP-NOS, IBS and AM, that appreciates the extensive array of available therapies in this field. We present the prospective operating procedure and technical summary protocol in this manuscript. Methods Grading of Recommendations, Assessment, Development and Evaluation (GRADE) will be followed in the development of the guideline, following the approach as laid out in the GRADE handbook, supported by the WHO. The Guideline Development Group (GDG) is formed by paediatric gastroenterologists from both the European Society for Pediatric Gastroenterology, Hepatology and Nutrition, as well as the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition. Also, one clinical psychologist with expertise in FAPDs is a voting member in the GDG. A final consensus list of treatment options is translated into ‘patient, intervention, comparison, outcome’ format options. Prospective agreement on the magnitude of health benefits or harms categories was reached through a Delphi process among the GDG to support grading of the literature. There will be a detailed technical evidence review with randomised controlled trial data that will be judged for risk of bias with the Cochrane tool. Recommendations are preferably based on GRADE but could also be best practice statements following the available evidence. A full Delphi process will be used to make recommendations using online response systems. This set of procedures has been approved by all members of the GDG.

Published
2023
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33. Role of inflammation in pediatric irritable bowel syndrome.

Author

Di Nardo, Giovanni, Cremon, Cesare, Staiano, Annamaria, Stanghellini, Vincenzo, Borrelli, Osvaldo, Strisciuglio, Caterina, Romano, Claudio, Mallardo, Saverio, Scarpato, Elena, Marasco, Giovanni, Salvatore, Silvia, Zenzeri, Letizia, Felici, Enrico, Pensabene, Licia, Sestito, Simona, Francavilla, Ruggiero, Quitadamo, Paolo, Baldassarre, Mariella, Giorgio, Valentina, and Tambucci, Renato

Subjects
IRRITABLE colon, INFLAMMATORY bowel diseases, CHILD patients, CELIAC disease, INFLAMMATION
Abstract

Background: IBS affects a large number of children throughout the world and is thought to be the result of disturbed neuroimmune function along with the brain–gut axis. Although the underlying pathophysiologic mechanisms are not clear, the role of low‐grade inflammation and mucosal immune activation in IBS symptom generation has become evident also in subsets of pediatric patients. Animal models provided meaningful insight in the causal relationship between abnormal mucosal immune activation and changes in gastrointestinal (GI) sensory‐motor function. Likewise, the development of long‐standing GI symptoms fulfilling the current criteria for functional GI disorders after infection gastroenteritis and in patients with IBD or celiac disease in remission further supports this hypothesis. Immune activation, its impact on gut sensory‐motor function, and potential implications for symptom generation emerged in both children and adults with IBS. Purpose: The aim of this review is to summarize the main evidence on the presence of low‐grade inflammation and immune activation in children with IBS, its possible role in symptom generation, and its potential implication for new therapeutic strategies. [ABSTRACT FROM AUTHOR]

Published
2023
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34. O13 Working definition of gastrointestinal dystonia of severe neuro-disability; outcome of the BSPGHAN/BAPM/BAPS/APPM/BPNA appropriateness panel

Author

Barclay, Andrew, primary, Meade, Susanna, additional, Richards, Catherine, additional, Warlow, Timothy, additional, Lumsden, Daniel, additional, Fairhurst, Charlie, additional, Paxton, Catherine, additional, Forrest, Katharine, additional, Mordekar, Santosh, additional, Campbell, David, additional, Thomas, Julian, additional, Brooks, Michelle, additional, Walker, Gregor, additional, Borrelli, Osvaldo, additional, Wells, Helen, additional, Holt, Susie, additional, Quinn, Shoana, additional, Liang, Yifan, additional, Mutalib, Mohammed, additional, Cernat, Elena, additional, Lee, Alex, additional, Lundy, Claire, additional, McGelliot, Fiona, additional, Griffiths, Jo, additional, Eunson, Paul, additional, Norton, Haidee, additional, Whyte, Lisa, additional, Samaan, Mark, additional, and Protheroe, Sue, additional

Published
2022
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37. European guideline on indications, performance, and clinical impact of hydrogen and methane breath tests in adult and pediatric patients: European Association for Gastroenterology, Endoscopy and Nutrition, European Society of Neurogastroenterology and Motility, and European Society for Paediatric Gastroenterology Hepatology and Nutrition consensus

Author

Hammer, Heinz F, Fox, Mark R, Keller, Jutta, Salvatore, Silvia, Basilisco, Guido, Hammer, Johann, Lopetuso, Loris, Benninga, Marc, Borrelli, Osvaldo, Dumitrascu, Dan, Hauser, Bruno, Herszenyi, Laszlo, Nakov, Radislav, Pohl, Daniel, Thapar, Nikhil, Sonyi, Marc, University of Zurich, and Hammer, Heinz F

Subjects
10219 Clinic for Gastroenterology and Hepatology, 610 Medicine & health, 2730 Oncology, 2715 Gastroenterology
Published
2022

38. Additional file 6 of Cyclic vomiting syndrome in children: a nationwide survey of current practice on behalf of the Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition (SIGENP) and Italian Society of Pediatric Neurology (SINP)

Author

Isoldi, Sara, Di Nardo, Giovanni, Mallardo, Saverio, Parisi, Pasquale, Raucci, Umberto, Tambucci, Renato, Quitadamo, Paolo, Salvatore, Silvia, Felici, Enrico, Cisarò, Fabio, Pensabene, Licia, Banzato, Claudia, Strisciuglio, Caterina, Romano, Claudio, Fusco, Patrizia, Rigotti, Francesca, Sansotta, Naire, Caimmi, Silvia, Savasta, Salvatore, Zuin, Giovanna, Di Stefano, Marina, Provera, Silvia, Campanozzi, Angelo, Rossi, Paolo, Gatti, Simona, Corpino, Mara, Alvisi, Patrizia, Martelossi, Stefano, Suppiej, Agnese, Gandullia, Paolo, Verrotti, Alberto, Terrin, Gianluca, Pacenza, Caterina, Fornaroli, Fabiola, Comito, Donatella, D’Arrigo, Stefano, Striano, Pasquale, Raviglione, Federico, Carotenuto, Marco, Orsini, Alessandro, Belcastro, Vincenzo, Di Corcia, Giovanna, Raieli, Vincenzo, Ferilli, Michela Ada Noris, Ruscitto, Claudia, Spadoni, Elisabetta, Grosso, Salvatore, D’Alonzo, Renato, Papa, Amanda, Pavone, Piero, Meli, Mariaclaudia, Velardita, Mario, Mainetti, Martina, Vanacore, Nicola, and Borrelli, Osvaldo

Abstract

Additional file 6: Supplementary Table 6. Screening tests performed among patients with cyclic vomiting syndrome according to specific outpatient clinic.

Published
2022
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39. Additional file 4 of Cyclic vomiting syndrome in children: a nationwide survey of current practice on behalf of the Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition (SIGENP) and Italian Society of Pediatric Neurology (SINP)

Author

Isoldi, Sara, Di Nardo, Giovanni, Mallardo, Saverio, Parisi, Pasquale, Raucci, Umberto, Tambucci, Renato, Quitadamo, Paolo, Salvatore, Silvia, Felici, Enrico, Cisarò, Fabio, Pensabene, Licia, Banzato, Claudia, Strisciuglio, Caterina, Romano, Claudio, Fusco, Patrizia, Rigotti, Francesca, Sansotta, Naire, Caimmi, Silvia, Savasta, Salvatore, Zuin, Giovanna, Di Stefano, Marina, Provera, Silvia, Campanozzi, Angelo, Rossi, Paolo, Gatti, Simona, Corpino, Mara, Alvisi, Patrizia, Martelossi, Stefano, Suppiej, Agnese, Gandullia, Paolo, Verrotti, Alberto, Terrin, Gianluca, Pacenza, Caterina, Fornaroli, Fabiola, Comito, Donatella, D’Arrigo, Stefano, Striano, Pasquale, Raviglione, Federico, Carotenuto, Marco, Orsini, Alessandro, Belcastro, Vincenzo, Di Corcia, Giovanna, Raieli, Vincenzo, Ferilli, Michela Ada Noris, Ruscitto, Claudia, Spadoni, Elisabetta, Grosso, Salvatore, D’Alonzo, Renato, Papa, Amanda, Pavone, Piero, Meli, Mariaclaudia, Velardita, Mario, Mainetti, Martina, Vanacore, Nicola, and Borrelli, Osvaldo

Abstract

Additional file 4: Supplementary Table 4. Family history of diseases detected among patients with cyclic vomiting syndrome according to specific outpatient clinic.

Published
2022
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40. Additional file 2 of Cyclic vomiting syndrome in children: a nationwide survey of current practice on behalf of the Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition (SIGENP) and Italian Society of Pediatric Neurology (SINP)

Author

Isoldi, Sara, Di Nardo, Giovanni, Mallardo, Saverio, Parisi, Pasquale, Raucci, Umberto, Tambucci, Renato, Quitadamo, Paolo, Salvatore, Silvia, Felici, Enrico, Cisarò, Fabio, Pensabene, Licia, Banzato, Claudia, Strisciuglio, Caterina, Romano, Claudio, Fusco, Patrizia, Rigotti, Francesca, Sansotta, Naire, Caimmi, Silvia, Savasta, Salvatore, Zuin, Giovanna, Di Stefano, Marina, Provera, Silvia, Campanozzi, Angelo, Rossi, Paolo, Gatti, Simona, Corpino, Mara, Alvisi, Patrizia, Martelossi, Stefano, Suppiej, Agnese, Gandullia, Paolo, Verrotti, Alberto, Terrin, Gianluca, Pacenza, Caterina, Fornaroli, Fabiola, Comito, Donatella, D’Arrigo, Stefano, Striano, Pasquale, Raviglione, Federico, Carotenuto, Marco, Orsini, Alessandro, Belcastro, Vincenzo, Di Corcia, Giovanna, Raieli, Vincenzo, Ferilli, Michela Ada Noris, Ruscitto, Claudia, Spadoni, Elisabetta, Grosso, Salvatore, D’Alonzo, Renato, Papa, Amanda, Pavone, Piero, Meli, Mariaclaudia, Velardita, Mario, Mainetti, Martina, Vanacore, Nicola, and Borrelli, Osvaldo

Abstract

Additional file 2: Supplementary Table 2. Main organic causes of vomiting identified in patients with suspected cyclic vomiting syndrome according to specific outpatient clinic.

Published
2022
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41. Additional file 7 of Cyclic vomiting syndrome in children: a nationwide survey of current practice on behalf of the Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition (SIGENP) and Italian Society of Pediatric Neurology (SINP)

Author

Isoldi, Sara, Di Nardo, Giovanni, Mallardo, Saverio, Parisi, Pasquale, Raucci, Umberto, Tambucci, Renato, Quitadamo, Paolo, Salvatore, Silvia, Felici, Enrico, Cisarò, Fabio, Pensabene, Licia, Banzato, Claudia, Strisciuglio, Caterina, Romano, Claudio, Fusco, Patrizia, Rigotti, Francesca, Sansotta, Naire, Caimmi, Silvia, Savasta, Salvatore, Zuin, Giovanna, Di Stefano, Marina, Provera, Silvia, Campanozzi, Angelo, Rossi, Paolo, Gatti, Simona, Corpino, Mara, Alvisi, Patrizia, Martelossi, Stefano, Suppiej, Agnese, Gandullia, Paolo, Verrotti, Alberto, Terrin, Gianluca, Pacenza, Caterina, Fornaroli, Fabiola, Comito, Donatella, D’Arrigo, Stefano, Striano, Pasquale, Raviglione, Federico, Carotenuto, Marco, Orsini, Alessandro, Belcastro, Vincenzo, Di Corcia, Giovanna, Raieli, Vincenzo, Ferilli, Michela Ada Noris, Ruscitto, Claudia, Spadoni, Elisabetta, Grosso, Salvatore, D’Alonzo, Renato, Papa, Amanda, Pavone, Piero, Meli, Mariaclaudia, Velardita, Mario, Mainetti, Martina, Vanacore, Nicola, and Borrelli, Osvaldo

Abstract

Additional file 7: Supplementary Table 7. Treatments applied in patients with cyclic vomiting syndrome according to specific outpatient clinic.

Published
2022
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42. Additional file 1 of Cyclic vomiting syndrome in children: a nationwide survey of current practice on behalf of the Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition (SIGENP) and Italian Society of Pediatric Neurology (SINP)

Author

Isoldi, Sara, Di Nardo, Giovanni, Mallardo, Saverio, Parisi, Pasquale, Raucci, Umberto, Tambucci, Renato, Quitadamo, Paolo, Salvatore, Silvia, Felici, Enrico, Cisarò, Fabio, Pensabene, Licia, Banzato, Claudia, Strisciuglio, Caterina, Romano, Claudio, Fusco, Patrizia, Rigotti, Francesca, Sansotta, Naire, Caimmi, Silvia, Savasta, Salvatore, Zuin, Giovanna, Di Stefano, Marina, Provera, Silvia, Campanozzi, Angelo, Rossi, Paolo, Gatti, Simona, Corpino, Mara, Alvisi, Patrizia, Martelossi, Stefano, Suppiej, Agnese, Gandullia, Paolo, Verrotti, Alberto, Terrin, Gianluca, Pacenza, Caterina, Fornaroli, Fabiola, Comito, Donatella, D’Arrigo, Stefano, Striano, Pasquale, Raviglione, Federico, Carotenuto, Marco, Orsini, Alessandro, Belcastro, Vincenzo, Di Corcia, Giovanna, Raieli, Vincenzo, Ferilli, Michela Ada Noris, Ruscitto, Claudia, Spadoni, Elisabetta, Grosso, Salvatore, D’Alonzo, Renato, Papa, Amanda, Pavone, Piero, Meli, Mariaclaudia, Velardita, Mario, Mainetti, Martina, Vanacore, Nicola, and Borrelli, Osvaldo

Abstract

Additional file 1: Supplementary Table 1. Web-based Questionnaire [original language].

Published
2022
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43. Additional file 3 of Cyclic vomiting syndrome in children: a nationwide survey of current practice on behalf of the Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition (SIGENP) and Italian Society of Pediatric Neurology (SINP)

Author

Isoldi, Sara, Di Nardo, Giovanni, Mallardo, Saverio, Parisi, Pasquale, Raucci, Umberto, Tambucci, Renato, Quitadamo, Paolo, Salvatore, Silvia, Felici, Enrico, Cisarò, Fabio, Pensabene, Licia, Banzato, Claudia, Strisciuglio, Caterina, Romano, Claudio, Fusco, Patrizia, Rigotti, Francesca, Sansotta, Naire, Caimmi, Silvia, Savasta, Salvatore, Zuin, Giovanna, Di Stefano, Marina, Provera, Silvia, Campanozzi, Angelo, Rossi, Paolo, Gatti, Simona, Corpino, Mara, Alvisi, Patrizia, Martelossi, Stefano, Suppiej, Agnese, Gandullia, Paolo, Verrotti, Alberto, Terrin, Gianluca, Pacenza, Caterina, Fornaroli, Fabiola, Comito, Donatella, D’Arrigo, Stefano, Striano, Pasquale, Raviglione, Federico, Carotenuto, Marco, Orsini, Alessandro, Belcastro, Vincenzo, Di Corcia, Giovanna, Raieli, Vincenzo, Ferilli, Michela Ada Noris, Ruscitto, Claudia, Spadoni, Elisabetta, Grosso, Salvatore, D’Alonzo, Renato, Papa, Amanda, Pavone, Piero, Meli, Mariaclaudia, Velardita, Mario, Mainetti, Martina, Vanacore, Nicola, and Borrelli, Osvaldo

Abstract

Additional file 3: Supplementary Table 3. Comorbidities recorded among patients with cyclic vomiting syndrome according to specific outpatient clinic.

Published
2022
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44. Additional file 5 of Cyclic vomiting syndrome in children: a nationwide survey of current practice on behalf of the Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition (SIGENP) and Italian Society of Pediatric Neurology (SINP)

Author

Isoldi, Sara, Di Nardo, Giovanni, Mallardo, Saverio, Parisi, Pasquale, Raucci, Umberto, Tambucci, Renato, Quitadamo, Paolo, Salvatore, Silvia, Felici, Enrico, Cisarò, Fabio, Pensabene, Licia, Banzato, Claudia, Strisciuglio, Caterina, Romano, Claudio, Fusco, Patrizia, Rigotti, Francesca, Sansotta, Naire, Caimmi, Silvia, Savasta, Salvatore, Zuin, Giovanna, Di Stefano, Marina, Provera, Silvia, Campanozzi, Angelo, Rossi, Paolo, Gatti, Simona, Corpino, Mara, Alvisi, Patrizia, Martelossi, Stefano, Suppiej, Agnese, Gandullia, Paolo, Verrotti, Alberto, Terrin, Gianluca, Pacenza, Caterina, Fornaroli, Fabiola, Comito, Donatella, D’Arrigo, Stefano, Striano, Pasquale, Raviglione, Federico, Carotenuto, Marco, Orsini, Alessandro, Belcastro, Vincenzo, Di Corcia, Giovanna, Raieli, Vincenzo, Ferilli, Michela Ada Noris, Ruscitto, Claudia, Spadoni, Elisabetta, Grosso, Salvatore, D’Alonzo, Renato, Papa, Amanda, Pavone, Piero, Meli, Mariaclaudia, Velardita, Mario, Mainetti, Martina, Vanacore, Nicola, and Borrelli, Osvaldo

Abstract

Additional file 5: Supplementary Table 5. Triggers recorded among patients with cyclic vomiting syndrome according to specific outpatient clinic.

Published
2022
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45. Sa2055 SYSTEMATIC REVIEW AND META-ANALYSIS FOR TREATMENT OF IRRITABLE BOWEL SYNDROME AND FUNCTIONAL ABDOMINAL PAIN – NOT OTHERWISE SPECIFIED IN CHILDREN

Author

Sinopoulou, Vassiliki, Groen, Jip, Gordon, Morris, Chogle, Ashish, Benninga, Marc A., Borlack, Rachel, Borrelli, Osvaldo, Darbari, Anil, Dolinsek, Jernej, Khlevner, Julie, Lorenzo, Carlo Di, Person, Hannibal, Sanghavi, Rinarani M., Snyder, Julie, Thapar, Nikhil, Vlieger, Arine, Saps, Miguel, and Tabbers, Merit

Published
2024
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46. Drugs in Focus

Author

Puoti, Maria Giovanna, Assa, Amit, Benninga, Marc, Broekaert, Ilse Julia, Carpi, Francisco Javier Martin, Deganello Saccomani, Marco, Dolinsek, Jernej, Homan, Matjaz, Mas, Emmanuel, Miele, Erasmo, Tzivinikos, Christos, Thomson, Mike, and Borrelli, Osvaldo

Abstract

Domperidone is a peripheral dopamine-2 receptor antagonist with prokinetic and antiemetic properties. Its prokinetic effects are mainly manifest in the upper gastrointestinal (GI) tract. Currently its use is restricted to relief of nausea and vomiting in children older than 12 years for a short period of time. However, among (pediatric) gastroenterologists, domperidone is also used outside its authorized indication (“off label”) for treatment of symptoms associated with gastro-esophageal reflux disease, dyspepsia, and gastroparesis. Little is known about its efficacy in the treatment of GI motility disorders in children and controversial data have emerged in the pediatric literature. As its use is off label, appropriate knowledge of its efficacy is helpful to support an “off label/on evidence” prescription. Based on this, the purpose of this review is to summarize all evidence on the efficacy of domperidone for the treatment of GI disorders in infants and children and to report an overview of its pharmacological properties and safety profile.

Published
2023
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48. Hematemesis in Infants

Author

Quitadamo, Paolo, primary, Anselmi, Federica, additional, Mantegazza, Cecilia, additional, Tambucci, Renato, additional, Campanozzi, Angelo, additional, Malamisura, Monica, additional, Raucci, Umberto, additional, Tipo, Vincenzo, additional, Dolce, Pasquale, additional, Saccomani, Marco Deganello, additional, Chiaro, Andrea, additional, Mancini, Valentina, additional, Felici, Enrico, additional, Orizio, Paolo, additional, Parma, Barbara, additional, Salvatore, Silvia, additional, and Borrelli, Osvaldo, additional

Published
2021
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49. Enhancing the utility of antroduodenal manometry in pediatric intestinal pseudo‐obstruction.

Author

Chanpong, Atchariya, Cronin, Hannah, Rampling, Dyanne, Ashworth, Michael, Eaton, Simon, Rybak, Anna, Saliakellis, Efstratios, Lindley, Keith J., Borrelli, Osvaldo, and Thapar, Nikhil

Subjects
INTESTINES, HISTOPATHOLOGY, GASTROINTESTINAL motility, STATISTICAL correlation, SMALL intestine
Abstract

Background: Antroduodenal manometry (ADM) and histopathology are currently employed to aid the diagnosis of pediatric intestinal pseudo‐obstruction (PIPO). Limited data are available on the reliability of ADM analysis and its correlation with histopathology. We aimed to develop a protocol for enhanced analysis of ADM contractile patterns, including a scoring system, and explore whether this provided better correlation with histopathology. Methods: Children referred with suspected PIPO between April 2012‐December 2019 who underwent both ADM and full‐thickness biopsies were included. ADM tracings were analyzed using both standard (conventional ADM) and novel (enhanced ADM) motility parameters. A novel ADM score (GLASS score) was generated based on the enhanced ADM analysis. Conventional and enhanced ADM analyses were then correlated with histopathology. Results: Forty patients were included. Using conventional clinical criteria, 29 of these were diagnosed with PIPO and the other 11 with non‐PIPO diagnoses. Twenty‐three of the PIPO patients had abnormal histopathology: 6 myopathy, 4 neuropathy, 3 neuro‐myopathy, and 10 non‐specific changes. No agreement in diagnosis was found between conventional ADM analysis and histopathology (ϰ = 0.068; p = 0.197), whereas the latter significantly correlated with enhanced ADM analysis (ϰ = 0.191; p = 0.003). The enhanced ADM score was significantly higher in PIPO versus non‐PIPO (16.0 vs. 8.0; p < 0.001). Conclusions: As opposed to conventional analysis protocols, the newly developed enhanced ADM analysis and associated score is not only able to discriminate between PIPO and non‐PIPO patients, but also between distinct histopathological pathologies. Further studies are required to assess the utility of enhanced ADM analysis in larger populations. [ABSTRACT FROM AUTHOR]

Published
2022
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