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Your search keyword '"Bian, Zehua"' showing total 26 results
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26 results on '"Bian, Zehua"'

1. A novel CAR-T cell product targeting CD74 is an effective therapeutic approach in preclinical mantle cell lymphoma models

Author

Chan, Wing Keung, Williams, Jessica, Sorathia, Kinnari, Pray, Betsy, Abusaleh, Kaled, Bian, Zehua, Sharma, Archisha, Hout, Ian, Nishat, Shamama, Hanel, Walter, Sloan, Shelby L., Yasin, Aneeq, Denlinger, Nathan, Zhang, Xiaoli, Muthusamy, Natarajan, Vasu, Sumithira, de Lima, Marcos, Yang, Yiping, Baiocchi, Robert, and Alinari, Lapo

Published
2023
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9. Figure S1-S11 from LncRNA–FEZF1-AS1 Promotes Tumor Proliferation and Metastasis in Colorectal Cancer by Regulating PKM2 Signaling

Author

Bian, Zehua, primary, Zhang, Jiwei, primary, Li, Min, primary, Feng, Yuyang, primary, Wang, Xue, primary, Zhang, Jia, primary, Yao, Surui, primary, Jin, Guoying, primary, Du, Jun, primary, Han, Weifeng, primary, Yin, Yuan, primary, Huang, Shenglin, primary, Fei, Bojian, primary, Zou, Jian, primary, and Huang, Zhaohui, primary

Published
2023
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10. Supplementary Figure S2 from miR-204-5p Inhibits Proliferation and Invasion and Enhances Chemotherapeutic Sensitivity of Colorectal Cancer Cells by Downregulating RAB22A

Author

Yin, Yuan, primary, Zhang, Binbin, primary, Wang, Weili, primary, Fei, Bojian, primary, Quan, Chao, primary, Zhang, Jiwei, primary, Song, Mingxu, primary, Bian, Zehua, primary, Wang, Qifeng, primary, Ni, Shujuan, primary, Hu, Yaling, primary, Mao, Yong, primary, Zhou, Leyuan, primary, Wang, Yugang, primary, Yu, Jian, primary, Du, Xiang, primary, Hua, Dong, primary, and Huang, Zhaohui, primary

Published
2023
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11. Supplementary Table S1, Table S2 and Figure legends from miR-204-5p Inhibits Proliferation and Invasion and Enhances Chemotherapeutic Sensitivity of Colorectal Cancer Cells by Downregulating RAB22A

Author

Yin, Yuan, primary, Zhang, Binbin, primary, Wang, Weili, primary, Fei, Bojian, primary, Quan, Chao, primary, Zhang, Jiwei, primary, Song, Mingxu, primary, Bian, Zehua, primary, Wang, Qifeng, primary, Ni, Shujuan, primary, Hu, Yaling, primary, Mao, Yong, primary, Zhou, Leyuan, primary, Wang, Yugang, primary, Yu, Jian, primary, Du, Xiang, primary, Hua, Dong, primary, and Huang, Zhaohui, primary

Published
2023
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12. Supplementary Materials and Methods from The Immune-microenvironment Confers Chemoresistance of Colorectal Cancer through Macrophage-Derived IL6

Author

Yin, Yuan, primary, Yao, Surui, primary, Hu, Yaling, primary, Feng, Yuyang, primary, Li, Min, primary, Bian, Zehua, primary, Zhang, Jiwei, primary, Qin, Yan, primary, Qi, Xiaowei, primary, Zhou, Leyuan, primary, Fei, Bojian, primary, Zou, Jian, primary, Hua, Dong, primary, and Huang, Zhaohui, primary

Published
2023
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13. Tale S1, S2, S4 from LncRNA–FEZF1-AS1 Promotes Tumor Proliferation and Metastasis in Colorectal Cancer by Regulating PKM2 Signaling

Author

Bian, Zehua, primary, Zhang, Jiwei, primary, Li, Min, primary, Feng, Yuyang, primary, Wang, Xue, primary, Zhang, Jia, primary, Yao, Surui, primary, Jin, Guoying, primary, Du, Jun, primary, Han, Weifeng, primary, Yin, Yuan, primary, Huang, Shenglin, primary, Fei, Bojian, primary, Zou, Jian, primary, and Huang, Zhaohui, primary

Published
2023
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14. MG53 preserves mitochondrial integrity of cardiomyocytes during ischemia reperfusion-induced oxidative stress

Author

Gumpper-Fedus, Kristyn, primary, Park, Ki Ho, additional, Ma, Hanley, additional, Zhou, Xinyu, additional, Bian, Zehua, additional, Krishnamurthy, Karthikeyan, additional, Sermersheim, Matthew, additional, Zhou, Jingsong, additional, Tan, Tao, additional, Li, Lei, additional, Liu, Jianxun, additional, Lin, Pei-Hui, additional, Zhu, Hua, additional, and Ma, Jianjie, additional

Published
2022
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17. Colorectal Cancer‐Derived Small Extracellular Vesicles Promote Tumor Immune Evasion by Upregulating PD‐L1 Expression in Tumor‐Associated Macrophages (Adv. Sci. 9/2022)

Author

Yin, Yuan, primary, Liu, Bingxin, additional, Cao, Yulin, additional, Yao, Surui, additional, Liu, Yuhang, additional, Jin, Guoying, additional, Qin, Yan, additional, Chen, Ying, additional, Cui, Kaisa, additional, Zhou, Leyuan, additional, Bian, Zehua, additional, Fei, Bojian, additional, Huang, Shenglin, additional, and Huang, Zhaohui, additional

Published
2022
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18. Additional file 1 of Long noncoding RNA DLGAP1-AS2 promotes tumorigenesis and metastasis by regulating the Trim21/ELOA/LHPP axis in colorectal cancer

Author

Wang, Xue, Cheng, Han, Zhao, Jing, Li, Jiuming, Chen, Ying, Cui, Kaisa, Tian, Lu, Zhang, Jia, Li, Chaoqun, Sun, Shengbai, Feng, Yuyang, Yao, Surui, Bian, Zehua, Huang, Shenglin, Fei, Bojian, and Huang, Zhaohui

Abstract

Additional file 1: Fig. S1. The expression and transcript analyses of DLGAP1-AS2. Fig. S2. Characterization of the protein-coding potential, subcellular localization and function for DLGAP1-AS2 in CRC. Fig. S3. HE staining for lung tissues from a lung metastasis mouse model. Fig. S4. Mass spectrometry analyses in samples from streptavidin pull down assays. Fig. S5. RIP assays. Fig. S6. Graphic illustration of predicted DLGAP1-AS2 secondary structure. Fig. S7. The effect of DLGAP1 on CPSF2, CSTF3 and ELOA in CRC. Fig. S8. DLGAP1-AS2 promoted the degradation of ELOA. Fig. S9. The function of ELOA andELOA as the downstream of DLGAP1-AS2. Fig. S10. The expression of LHPP and its relationship to ELOA in CRC. Fig. S11. CPSF2 and CSTF3 are associated with poor clinical outcomes in patients with CRC. Fig. S12. The effect of CPSF2 or CSTF3 on AKT. Tab. S1. Primer sequence. Tab. S2. siRNA sequences. Tab. S3. Relatedsequence information for plasmid construction. Tab. S4. The sequences for DLAGP1-AS2 and its deletion fragments used in vitro transcription. Tab. S5. Antibody information. Tab. S6. Relationships between DLGAP1-AS2 expression and clinical pathologic factors of the patients with CRC. Tab. S7. Relationships between ELOA expression and clinical pathologic factors of the patients with CRC.

Published
2022
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19. MG53 attenuates nitrogen mustard‐induced acute lung injury

Author

Li, Haichang, primary, Rosas, Lucia, additional, Li, Zhongguang, additional, Bian, Zehua, additional, Li, Xiuchun, additional, Choi, Kyounghan, additional, Cai, Chuanxi, additional, Zhou, Xinyu, additional, Tan, Tao, additional, Bergdall, Valerie, additional, Whitson, Bryan, additional, Davis, Ian, additional, and Ma, Jianjie, additional

Published
2022
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20. Long Noncoding RNA DLGAP1-AS2 Promotes Tumorigenesis and Metastasis by Regulating the Trim21/ELOA/LHPP Signaling Axis in Colorectal Cancer

Author

Wang, Xue, primary, Zhao, Jing, additional, Cheng, Han, additional, Li, Jiuming, additional, Chen, Ying, additional, Cui, Kaisa, additional, Tian, Lu, additional, Zhang, Jia, additional, Li, Chaoqun, additional, Sun, Shengbai, additional, Feng, Yuyang, additional, Yao, Surui, additional, Bian, Zehua, additional, Huang, Shenglin, additional, Fei, Bojian, additional, and Huang, Zhaohui, additional

Published
2022
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22. MicroRNA‐204‐5p: A pivotal tumor suppressor.

Author

Yang, Fan, Bian, Zehua, Xu, Peiwen, Sun, Shengbai, and Huang, Zhaohui

Subjects
*TRP channels, *NON-coding RNA, *CANCER prognosis, *CANCER fatigue
Abstract

MicroRNAs (miRNAs) are a class of non‐coding single‐stranded RNA molecules with a length of approximately 18‐25 nt nucleotides that regulate gene expression post‐transcriptionally. MiR‐204‐5p originates from the sixth intron of the transient receptor potential cation channel subfamily M member 3 (TRPM3) gene. MiR‐204‐5p is frequently downregulated in various cancer types and is related to the clinicopathological characteristics and prognosis of cancer patients. So far, many studies have determined that miR‐204‐5p functions as a tumor suppressor for its extensive and powerful capacity to inhibit tumor proliferation, metastasis, autophagy, and chemoresistance in multiple cancer types. MiR‐204‐5p appears to be a promising prognostic biomarker and a therapeutic target for human cancers. This review summarized the latest advances on the role of miR‐204‐5p in human cancers. [ABSTRACT FROM AUTHOR]

Published
2023
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23. Abstract 13835: MG53 Preserves Mitochondrial Integrity of Cardiomyocytes in Pre-Clinical Models of Ischemia Reperfusion-Induced Oxidative Stress

Author

Zhu, Hua, primary, Gumpper, Kristyn, additional, Ma, Hanley, additional, Zhou, Xinyu, additional, Bian, Zehua, additional, Krishnamurthy, Karthikeyan, additional, Park, Ki Ho, additional, Sermersheim, Matthew, additional, Zhou, Jingsong, additional, Tan, Tao, additional, Li, Lei, additional, Liu, Jianxun, additional, LIN, PEI-HUI, additional, and Ma, Jianjie, additional

Published
2021
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24. Abstract 11086: MG53 Suppresses NfκB Activation to Mitigate Age-Related Heart Failure

Author

wang, xiaoliang, primary, LI, XIUCHUN, additional, Ong, Hannah, additional, Tan, Tao, additional, Park, Ki Ho H, additional, Bian, Zehua, additional, Zou, Xunchang, additional, Haggard, Erin, additional, Janssen, Paul M, additional, Merritt, Robert E, additional, Pawlik, Timothy M, additional, Whitson, Bryan, additional, Mokadam, Nahush, additional, Cao, Lei, additional, Zhu, Hua, additional, Ma, Jianjie, additional, and Cai, Chuanxi, additional

Published
2021
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25. SNHG17 promotes colorectal tumorigenesis and metastasis via regulating Trim23-PES1 axis and miR-339-5p-FOSL2-SNHG17 positive feedback loop

Author

Bian, Zehua, primary, Zhou, Mingyue, additional, Cui, Kaisa, additional, Yang, Fan, additional, Cao, Yulin, additional, Sun, Shengbai, additional, Liu, Bingxin, additional, Gong, Liang, additional, Li, Jiuming, additional, Wang, Xue, additional, Li, Chaoqun, additional, Yao, Surui, additional, Yin, Yuan, additional, Huang, Shenglin, additional, Fei, Bojian, additional, and Huang, Zhaohui, additional

Published
2021
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26. A novel high-risk model identified by epithelial-mesenchymal transition predicts prognosis and radioresistance in rectal cancer.

Author

Qin F, Bian Z, Jiang L, Cao Y, Tang J, Ming L, Qin Y, Huang Z, and Yin Y

Subjects
Humans, Prognosis, Female, Male, Animals, Mice, Cell Line, Tumor, Middle Aged, Gene Expression Profiling, Epithelial-Mesenchymal Transition genetics, Rectal Neoplasms genetics, Rectal Neoplasms pathology, Rectal Neoplasms radiotherapy, Radiation Tolerance genetics, Gene Expression Regulation, Neoplastic, Biomarkers, Tumor genetics
Abstract

Many studies have shown that tumor cells that survive radiotherapy are more likely to metastasize, but the underlying mechanism remains unclear. Here we aimed to identify epithelial-mesenchymal transition (EMT)-related key genes, which associated with prognosis and radiosensitivity in rectal cancer. First, we obtained differentially expressed genes by analyzing the RNA expression profiles of rectal cancer retrieved from The Cancer Genome Atlas database, EMT-related genes, and radiotherapy-related databases, respectively. Then, Lasso and Cox regression analyses were used to establish an EMT-related prognosis model (EMTPM) based on the identified independent protective factor Fibulin5 (FBLN5) and independent risk gene EHMT2. The high-EMTPM group exhibited significantly poorer prognosis. Then, we evaluated the signature in an external clinical validation cohort. Through in vivo experiments, we further demonstrated that EMTPM effectively distinguishes radioresistant from radiosensitive patients with rectal cancer. Moreover, individuals in the high-EMTPM group showed increased expression of immune checkpoints compared to their counterparts. Finally, pan-cancer analysis of the EMTPM model also indicated its potential for predicting the prognosis of lung squamous cell carcinoma and breast cancer patients undergoing radiotherapy. In summary, we established a novel predictive model for rectal cancer prognosis and radioresistance based on FBLN5 and EHMT2 expressions, and suggested that immune microenvironment may be involved in the process of radioresistance. This predictive model could be used to select management strategies for rectal cancer., (© 2024 Wiley Periodicals LLC.)

Published
2024
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