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22 results on '"Berg‐Hansen, Pål"'

4. Peripapillary retinal layer thickness is associated with retinal oxygen saturation in newly diagnosed patients with multiple sclerosis

Author

Nes, Dragana, primary, Berg‐Hansen, Pål, additional, de Rodez Benavent, Sigrid A., additional, Høgestøl, Einar A., additional, Beyer, Mona K., additional, Rinker, Daniel A., additional, Veiby, Nina, additional, Karabeg, Mia, additional, Petrovski, Beáta Éva, additional, Celius, Elisabeth G., additional, Harbo, Hanne F., additional, and Petrovski, Goran, additional

Published
2024
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8. Serum neurofilament light chain concentration predicts disease worsening in multiple sclerosis

Author

Brune, Synne, primary, Høgestøl, Einar A, additional, de Rodez Benavent, Sigrid A, additional, Berg-Hansen, Pål, additional, Beyer, Mona K, additional, Leikfoss, Ingvild Sørum, additional, Bos, Steffan D, additional, Sowa, Piotr, additional, Brunborg, Cathrine, additional, Andorra, Magi, additional, Pulido Valdeolivas, Irene, additional, Asseyer, Susanna, additional, Brandt, Alexander, additional, Chien, Claudia, additional, Scheel, Michael, additional, Blennow, Kaj, additional, Zetterberg, Henrik, additional, Kerlero de Rosbo, Nicole, additional, Paul, Friedemann, additional, Uccelli, Antonio, additional, Villoslada, Pablo, additional, Berge, Tone, additional, and Harbo, Hanne F, additional

Published
2022
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9. Exploring Retinal Blood Vessel Diameters as Biomarkers in Multiple Sclerosis

Author

Drobnjak Nes, Dragana, primary, Berg-Hansen, Pål, additional, de Rodez Benavent, Sigrid A., additional, Høgestøl, Einar A., additional, Beyer, Mona K., additional, Rinker, Daniel A., additional, Veiby, Nina, additional, Karabeg, Mia, additional, Petrovski, Beáta Éva, additional, Celius, Elisabeth G., additional, Harbo, Hanne F., additional, and Petrovski, Goran, additional

Published
2022
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12. sj-pdf-2-msj-10.1177_13524585221097296 – Supplemental material for Serum neurofilament light chain concentration predicts disease worsening in multiple sclerosis

Author

Brune, Synne, Høgestøl, Einar A, de Rodez Benavent, Sigrid A, Berg-Hansen, Pål, Beyer, Mona K, Leikfoss, Ingvild Sørum, Bos, Steffan D, Sowa, Piotr, Brunborg, Cathrine, Andorra, Magi, Pulido Valdeolivas, Irene, Asseyer, Susanna, Brandt, Alexander, Chien, Claudia, Scheel, Michael, Blennow, Kaj, Zetterberg, Henrik, Kerlero de Rosbo, Nicole, Paul, Friedemann, Uccelli, Antonio, Villoslada, Pablo, Berge, Tone, and Harbo, Hanne F

Subjects
FOS: Clinical medicine, 111702 Aged Health Care, FOS: Health sciences, 110904 Neurology and Neuromuscular Diseases
Abstract

Supplemental material, sj-pdf-2-msj-10.1177_13524585221097296 for Serum neurofilament light chain concentration predicts disease worsening in multiple sclerosis by Synne Brune, Einar A Høgestøl, Sigrid A de Rodez Benavent, Pål Berg-Hansen, Mona K Beyer, Ingvild Sørum Leikfoss, Steffan D Bos, Piotr Sowa, Cathrine Brunborg, Magi Andorra, Irene Pulido Valdeolivas, Susanna Asseyer, Alexander Brandt, Claudia Chien, Michael Scheel, Kaj Blennow, Henrik Zetterberg, Nicole Kerlero de Rosbo, Friedemann Paul, Antonio Uccelli, Pablo Villoslada, Tone Berge and Hanne F Harbo in Multiple Sclerosis Journal

Published
2022
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13. sj-docx-13-msj-10.1177_13524585221097296 – Supplemental material for Serum neurofilament light chain concentration predicts disease worsening in multiple sclerosis

Author

Brune, Synne, Høgestøl, Einar A, de Rodez Benavent, Sigrid A, Berg-Hansen, Pål, Beyer, Mona K, Leikfoss, Ingvild Sørum, Bos, Steffan D, Sowa, Piotr, Brunborg, Cathrine, Andorra, Magi, Pulido Valdeolivas, Irene, Asseyer, Susanna, Brandt, Alexander, Chien, Claudia, Scheel, Michael, Blennow, Kaj, Zetterberg, Henrik, Kerlero de Rosbo, Nicole, Paul, Friedemann, Uccelli, Antonio, Villoslada, Pablo, Berge, Tone, and Harbo, Hanne F

Subjects
FOS: Clinical medicine, 111702 Aged Health Care, FOS: Health sciences, 110904 Neurology and Neuromuscular Diseases
Abstract

Supplemental material, sj-docx-13-msj-10.1177_13524585221097296 for Serum neurofilament light chain concentration predicts disease worsening in multiple sclerosis by Synne Brune, Einar A Høgestøl, Sigrid A de Rodez Benavent, Pål Berg-Hansen, Mona K Beyer, Ingvild Sørum Leikfoss, Steffan D Bos, Piotr Sowa, Cathrine Brunborg, Magi Andorra, Irene Pulido Valdeolivas, Susanna Asseyer, Alexander Brandt, Claudia Chien, Michael Scheel, Kaj Blennow, Henrik Zetterberg, Nicole Kerlero de Rosbo, Friedemann Paul, Antonio Uccelli, Pablo Villoslada, Tone Berge and Hanne F Harbo in Multiple Sclerosis Journal

Published
2022
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14. sj-docx-9-msj-10.1177_13524585221097296 – Supplemental material for Serum neurofilament light chain concentration predicts disease worsening in multiple sclerosis

Author

Brune, Synne, Høgestøl, Einar A, de Rodez Benavent, Sigrid A, Berg-Hansen, Pål, Beyer, Mona K, Leikfoss, Ingvild Sørum, Bos, Steffan D, Sowa, Piotr, Brunborg, Cathrine, Andorra, Magi, Pulido Valdeolivas, Irene, Asseyer, Susanna, Brandt, Alexander, Chien, Claudia, Scheel, Michael, Blennow, Kaj, Zetterberg, Henrik, Kerlero de Rosbo, Nicole, Paul, Friedemann, Uccelli, Antonio, Villoslada, Pablo, Berge, Tone, and Harbo, Hanne F

Subjects
FOS: Clinical medicine, 111702 Aged Health Care, FOS: Health sciences, 110904 Neurology and Neuromuscular Diseases
Abstract

Supplemental material, sj-docx-9-msj-10.1177_13524585221097296 for Serum neurofilament light chain concentration predicts disease worsening in multiple sclerosis by Synne Brune, Einar A Høgestøl, Sigrid A de Rodez Benavent, Pål Berg-Hansen, Mona K Beyer, Ingvild Sørum Leikfoss, Steffan D Bos, Piotr Sowa, Cathrine Brunborg, Magi Andorra, Irene Pulido Valdeolivas, Susanna Asseyer, Alexander Brandt, Claudia Chien, Michael Scheel, Kaj Blennow, Henrik Zetterberg, Nicole Kerlero de Rosbo, Friedemann Paul, Antonio Uccelli, Pablo Villoslada, Tone Berge and Hanne F Harbo in Multiple Sclerosis Journal

Published
2022
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15. sj-docx-8-msj-10.1177_13524585221097296 – Supplemental material for Serum neurofilament light chain concentration predicts disease worsening in multiple sclerosis

Author

Brune, Synne, Høgestøl, Einar A, de Rodez Benavent, Sigrid A, Berg-Hansen, Pål, Beyer, Mona K, Leikfoss, Ingvild Sørum, Bos, Steffan D, Sowa, Piotr, Brunborg, Cathrine, Andorra, Magi, Pulido Valdeolivas, Irene, Asseyer, Susanna, Brandt, Alexander, Chien, Claudia, Scheel, Michael, Blennow, Kaj, Zetterberg, Henrik, Kerlero de Rosbo, Nicole, Paul, Friedemann, Uccelli, Antonio, Villoslada, Pablo, Berge, Tone, and Harbo, Hanne F

Subjects
FOS: Clinical medicine, 111702 Aged Health Care, FOS: Health sciences, 110904 Neurology and Neuromuscular Diseases
Abstract

Supplemental material, sj-docx-8-msj-10.1177_13524585221097296 for Serum neurofilament light chain concentration predicts disease worsening in multiple sclerosis by Synne Brune, Einar A Høgestøl, Sigrid A de Rodez Benavent, Pål Berg-Hansen, Mona K Beyer, Ingvild Sørum Leikfoss, Steffan D Bos, Piotr Sowa, Cathrine Brunborg, Magi Andorra, Irene Pulido Valdeolivas, Susanna Asseyer, Alexander Brandt, Claudia Chien, Michael Scheel, Kaj Blennow, Henrik Zetterberg, Nicole Kerlero de Rosbo, Friedemann Paul, Antonio Uccelli, Pablo Villoslada, Tone Berge and Hanne F Harbo in Multiple Sclerosis Journal

Published
2022
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16. sj-pdf-3-msj-10.1177_13524585221097296 – Supplemental material for Serum neurofilament light chain concentration predicts disease worsening in multiple sclerosis

Author

Brune, Synne, Høgestøl, Einar A, de Rodez Benavent, Sigrid A, Berg-Hansen, Pål, Beyer, Mona K, Leikfoss, Ingvild Sørum, Bos, Steffan D, Sowa, Piotr, Brunborg, Cathrine, Andorra, Magi, Pulido Valdeolivas, Irene, Asseyer, Susanna, Brandt, Alexander, Chien, Claudia, Scheel, Michael, Blennow, Kaj, Zetterberg, Henrik, Kerlero de Rosbo, Nicole, Paul, Friedemann, Uccelli, Antonio, Villoslada, Pablo, Berge, Tone, and Harbo, Hanne F

Subjects
FOS: Clinical medicine, 111702 Aged Health Care, FOS: Health sciences, 110904 Neurology and Neuromuscular Diseases
Abstract

Supplemental material, sj-pdf-3-msj-10.1177_13524585221097296 for Serum neurofilament light chain concentration predicts disease worsening in multiple sclerosis by Synne Brune, Einar A Høgestøl, Sigrid A de Rodez Benavent, Pål Berg-Hansen, Mona K Beyer, Ingvild Sørum Leikfoss, Steffan D Bos, Piotr Sowa, Cathrine Brunborg, Magi Andorra, Irene Pulido Valdeolivas, Susanna Asseyer, Alexander Brandt, Claudia Chien, Michael Scheel, Kaj Blennow, Henrik Zetterberg, Nicole Kerlero de Rosbo, Friedemann Paul, Antonio Uccelli, Pablo Villoslada, Tone Berge and Hanne F Harbo in Multiple Sclerosis Journal

Published
2022
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17. sj-pdf-1-msj-10.1177_13524585221097296 – Supplemental material for Serum neurofilament light chain concentration predicts disease worsening in multiple sclerosis

Author

Brune, Synne, Høgestøl, Einar A, de Rodez Benavent, Sigrid A, Berg-Hansen, Pål, Beyer, Mona K, Leikfoss, Ingvild Sørum, Bos, Steffan D, Sowa, Piotr, Brunborg, Cathrine, Andorra, Magi, Pulido Valdeolivas, Irene, Asseyer, Susanna, Brandt, Alexander, Chien, Claudia, Scheel, Michael, Blennow, Kaj, Zetterberg, Henrik, Kerlero de Rosbo, Nicole, Paul, Friedemann, Uccelli, Antonio, Villoslada, Pablo, Berge, Tone, and Harbo, Hanne F

Subjects
FOS: Clinical medicine, 111702 Aged Health Care, FOS: Health sciences, 110904 Neurology and Neuromuscular Diseases
Abstract

Supplemental material, sj-pdf-1-msj-10.1177_13524585221097296 for Serum neurofilament light chain concentration predicts disease worsening in multiple sclerosis by Synne Brune, Einar A Høgestøl, Sigrid A de Rodez Benavent, Pål Berg-Hansen, Mona K Beyer, Ingvild Sørum Leikfoss, Steffan D Bos, Piotr Sowa, Cathrine Brunborg, Magi Andorra, Irene Pulido Valdeolivas, Susanna Asseyer, Alexander Brandt, Claudia Chien, Michael Scheel, Kaj Blennow, Henrik Zetterberg, Nicole Kerlero de Rosbo, Friedemann Paul, Antonio Uccelli, Pablo Villoslada, Tone Berge and Hanne F Harbo in Multiple Sclerosis Journal

Published
2022
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18. sj-pdf-4-msj-10.1177_13524585221097296 – Supplemental material for Serum neurofilament light chain concentration predicts disease worsening in multiple sclerosis

Author

Brune, Synne, Høgestøl, Einar A, de Rodez Benavent, Sigrid A, Berg-Hansen, Pål, Beyer, Mona K, Leikfoss, Ingvild Sørum, Bos, Steffan D, Sowa, Piotr, Brunborg, Cathrine, Andorra, Magi, Pulido Valdeolivas, Irene, Asseyer, Susanna, Brandt, Alexander, Chien, Claudia, Scheel, Michael, Blennow, Kaj, Zetterberg, Henrik, Kerlero de Rosbo, Nicole, Paul, Friedemann, Uccelli, Antonio, Villoslada, Pablo, Berge, Tone, and Harbo, Hanne F

Subjects
FOS: Clinical medicine, 111702 Aged Health Care, FOS: Health sciences, 110904 Neurology and Neuromuscular Diseases
Abstract

Supplemental material, sj-pdf-4-msj-10.1177_13524585221097296 for Serum neurofilament light chain concentration predicts disease worsening in multiple sclerosis by Synne Brune, Einar A Høgestøl, Sigrid A de Rodez Benavent, Pål Berg-Hansen, Mona K Beyer, Ingvild Sørum Leikfoss, Steffan D Bos, Piotr Sowa, Cathrine Brunborg, Magi Andorra, Irene Pulido Valdeolivas, Susanna Asseyer, Alexander Brandt, Claudia Chien, Michael Scheel, Kaj Blennow, Henrik Zetterberg, Nicole Kerlero de Rosbo, Friedemann Paul, Antonio Uccelli, Pablo Villoslada, Tone Berge and Hanne F Harbo in Multiple Sclerosis Journal

Published
2022
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19. Information from ecological momentary assessments lead to over-medicalization: Yes.

Author

Høgestøl, Einar A and Berg-Hansen, Pål

Subjects
*MEDICAL terminology, *SLEEP quality, *SLEEP, *BEHAVIOR disorders, *SYMPTOM burden, *ECOLOGICAL momentary assessments (Clinical psychology)
Abstract

This article discusses the use of ecological momentary assessment (EMA) in capturing real-time data on individuals' behaviors and experiences in their natural environments. EMA has been utilized in various research domains, including studies on multiple sclerosis (MS), to evaluate neurological symptoms and explore associations between physical activity and MS symptoms. However, the integration of EMA into routine care raises concerns about over-medicalization, increased stress levels, unnecessary clinical examinations, and the reliability of self-reported data. Careful consideration is needed to balance the benefits of EMA with its potential psychological impact and overutilization of healthcare resources. [Extracted from the article]

Published
2024
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20. A Comparison of Brain Age Estimation And Brain Parenchymal Fraction as Imaging Markers in Multiple Sclerosis

Author

Høgestøl, Einar August, primary, Kaufmann, Tobias, additional, de Lange, Ann-Marie G., additional, Moridi, Thomas, additional, Ouellette, Russel, additional, Pedersen, Mads L., additional, Ineichen, Benjamin Victor, additional, Beck, Dani, additional, Ferrerira, Daniel, additional, Muehlboeck, Sebastian, additional, Brune, Synne, additional, Nygaard, Gro Owren, additional, Berg-Hansen, Pål, additional, Beyer, Mona Kristiansen, additional, Sowa, Piotr, additional, Manouchehrinia, Ali, additional, Westman, Eric, additional, Olsson, Tomas, additional, Celius, Elisabeth Gulowsen, additional, Hillert, Jan, additional, Kockum, Ingrid Skelton, additional, Harbo, Hanne Flinstad, additional, Piehl, Fredrik, additional, Granberg, Tobias, additional, and Westlye, Lars T., additional

Published
2022
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21. Clinical and laboratory characteristics during a 1‐year follow‐up in European Lyme neuroborreliosis: A prospective cohort study.

Author

Solheim, Anne Marit, Skarstein, Ingerid, Quarsten, Hanne, Lorentzen, Åslaug Rudjord, Berg‐Hansen, Pål, Eikeland, Randi, Reiso, Harald, Mygland, Åse, and Ljøstad, Unn

Subjects
*LYME neuroborreliosis, *SYMPTOM burden, *CEREBROSPINAL fluid, *BORRELIA burgdorferi, *FACIAL paralysis
Abstract

Background and Purpose Methods Results Conclusions We need more knowledge on clinical presentations, time course, biomarkers, and prognosis in European Lyme neuroborreliosis (LNB).A prospective 12‐month follow‐up of predetermined clinical and laboratory parameters was undertaken in 105 patients with LNB.At presentation, 79% had radiculopathy, 49% had facial palsy, and 13% had solely subjective symptoms (predominately pain). Intrathecally produced Borrelia burgdorferi (Bb) antibodies were demonstrated and cerebrospinal fluid (CSF) CXCL13 was positive in 85% and 82% pretreatment, in 73% and 10% at 6 months, and in 58% and 14% at 12 months, respectively. CSF Bb polymerase chain reaction (PCR) was positive in 40% pretreatment. In four patients who tested negative for Bb antibodies in both serum and CSF, the diagnosis was supported by typical clinical features, pleocytosis, CSF Bb‐PCR (n = 1), or CSF CXCL13 (n = 2). The proportion with symptoms influencing daily life was 91% pretreatment, 25% at 10 weeks, 20% at 6 months, and 15% at 12 months. Fatigue was the most common complaint at 12 months. A high burden of symptoms before and after treatment was associated with residual complaints at 12 months, whereas background data, other clinical features, and laboratory features were not.LNB can present with solely subjective symptoms, especially pain. Many LNB patients have persistent Bb antibodies in serum and CSF. In seronegative LNB, CSF Bb‐PCR and CXCL13 may give diagnostic support. CXCL13 may be persistently positive after treatment in some patients. Most of the clinical improvement occurs during the first 10 weeks. High initial clinical score is associated with poorer outcome. [ABSTRACT FROM AUTHOR]

Published
2024
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22. Serum neurofilament light chain concentration predicts disease worsening in multiple sclerosis.

Author

Brune S, Høgestøl EA, de Rodez Benavent SA, Berg-Hansen P, Beyer MK, Leikfoss IS, Bos SD, Sowa P, Brunborg C, Andorra M, Pulido Valdeolivas I, Asseyer S, Brandt A, Chien C, Scheel M, Blennow K, Zetterberg H, Kerlero de Rosbo N, Paul F, Uccelli A, Villoslada P, Berge T, and Harbo HF

Subjects
Biomarkers, Brain diagnostic imaging, Brain pathology, Humans, Intermediate Filaments pathology, Magnetic Resonance Imaging, Neurofilament Proteins, Multiple Sclerosis pathology
Abstract

Background: Serum neurofilament light (sNfL) chain is a promising biomarker reflecting neuro-axonal injury in multiple sclerosis (MS). However, the ability of sNfL to predict outcomes in real-world MS cohorts requires further validation., Objective: The aim of the study is to investigate the associations of sNfL concentration, magnetic resonance imaging (MRI) and retinal optical coherence tomography (OCT) markers with disease worsening in a longitudinal European multicentre MS cohort., Methods: MS patients ( n  = 309) were prospectively enrolled at four centres and re-examined after 2 years ( n  = 226). NfL concentration was measured by single molecule array assay in serum. The patients' phenotypes were thoroughly characterized with clinical examination, retinal OCT and MRI brain scans. The primary outcome was disease worsening at median 2-year follow-up., Results: Patients with high sNfL concentrations (⩾8 pg/mL) at baseline had increased risk of disease worsening at median 2-year follow-up (odds ratio (95% confidence interval) = 2.8 (1.5-5.3), p  = 0.001). We found no significant associations of MRI or OCT measures at baseline with risk of disease worsening., Conclusion: Serum NfL concentration was the only factor associated with disease worsening, indicating that sNfL is a useful biomarker in MS that might be relevant in a clinical setting.

Published
2022
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