10 results on '"Barr, Dana B."'
Search Results
2. Placental PFAS concentrations are associated with perturbations of placental DNA methylation at loci with important roles on cardiometabolic health.
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Everson, Todd M, primary, Sehgal, Neha, additional, Barr, Dana B, additional, Panuwet, Parinya, additional, Yakimavets, Volha, additional, Perez, Cynthia, additional, Shankar, Kartik, additional, Eick, Stephanie M, additional, Pearson, Kevin J, additional, and Andres, Aline, additional
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- 2024
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3. Human Immune Cell Epigenomic Signatures in Response to Infectious Diseases and Chemical Exposures
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Wang, Wenliang, primary, Hariharan, Manoj, additional, Bartlett, Anna, additional, Barragan, Cesar, additional, Castanon, Rosa, additional, Rothenberg, Vince, additional, Song, Haili, additional, Nery, Joseph, additional, Aldridge, Andrew, additional, Altshul, Jordan, additional, Kenworthy, Mia, additional, Ding, Wubin, additional, Liu, Hanqing, additional, Tian, Wei, additional, Zhou, Jingtian, additional, Chen, Huaming, additional, Wei, Bei, additional, Gündüz, Irem B., additional, Norell, Todd, additional, Broderick, Timothy J, additional, McClain, Micah T., additional, Satterwhite, Lisa L., additional, Burke, Thomas W., additional, Petzold, Elizabeth A., additional, Shen, Xiling, additional, Woods, Christopher W., additional, Fowler, Vance G., additional, Ruffin, Felicia, additional, Panuwet, Parinya, additional, Barr, Dana B., additional, Beare, Jennifer L., additional, Smith, Anthony K., additional, Spurbeck, Rachel R., additional, Vangeti, Sindhu, additional, Ramos, Irene, additional, Nudelman, German, additional, Sealfon, Stuart C., additional, Castellino, Flora, additional, Walley, Anna Maria, additional, Evans, Thomas, additional, Müller, Fabian, additional, Greenleaf, William J., additional, and Ecker, Joseph R., additional
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- 2023
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4. Community‐Engaged Assessment of Soil Lead Contamination in Atlanta Urban Growing Spaces
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Peters, Samuel J. W., primary, Warner, Sydney M., additional, Saikawa, Eri, additional, Ryan, P. Barry, additional, Panuwet, Parinya, additional, Barr, Dana B., additional, D'Souza, Priya E., additional, Frank, Gil, additional, Hernandez, Rosario, additional, Alvarado, Taranji, additional, Hines, Arthur, additional, and Theal, Chris, additional
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- 2023
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5. Liquefied Petroleum Gas or Biomass for Cooking and Effects on Birth Weight
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Clasen, Thomas F., primary, Chang, Howard H., additional, Thompson, Lisa M., additional, Kirby, Miles A., additional, Balakrishnan, Kalpana, additional, Díaz-Artiga, Anaité, additional, McCracken, John P., additional, Rosa, Ghislaine, additional, Steenland, Kyle, additional, Younger, Ashley, additional, Aravindalochanan, Vigneswari, additional, Barr, Dana B., additional, Castañaza, Adly, additional, Chen, Yunyun, additional, Chiang, Marilú, additional, Clark, Maggie L., additional, Garg, Sarada, additional, Hartinger, Stella, additional, Jabbarzadeh, Shirin, additional, Johnson, Michael A., additional, Kim, Dong-Yun, additional, Lovvorn, Amy E., additional, McCollum, Eric D., additional, Monroy, Libny, additional, Moulton, Lawrence H., additional, Mukeshimana, Alexie, additional, Mukhopadhyay, Krishnendu, additional, Naeher, Luke P., additional, Ndagijimana, Florien, additional, Papageorghiou, Aris, additional, Piedrahita, Ricardo, additional, Pillarisetti, Ajay, additional, Puttaswamy, Naveen, additional, Quinn, Ashlinn, additional, Ramakrishnan, Usha, additional, Sambandam, Sankar, additional, Sinharoy, Sheela S., additional, Thangavel, Gurusamy, additional, Underhill, Lindsay J., additional, Waller, Lance A., additional, Wang, Jiantong, additional, Williams, Kendra N., additional, Rosenthal, Joshua P., additional, Checkley, William, additional, and Peel, Jennifer L., additional
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- 2022
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6. Liquefied Petroleum Gas or Biomass for Cooking and Effects on Birth Weight
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Clasen, Thomas F., Chang, Howard H., Thompson, Lisa M., Kirby, Miles A., Balakrishnan, Kalpana, Diaz-Artiga, Anaite, McCracken, John P., Rosa, Ghislaine, Steenland, Kyle, Younger, Ashley, Aravindalochanan, Vigneswari, Barr, Dana B, Castanaza, Adly, Chen, Yunyun, Chiang, Marilu, Clark, Maggie L., Garg, Sarada, Hartinger Peña, Stella Maria, Jabbarzadeh, Shirin, Johnson, Michael A., Kim, Dong-Yun, Lovvorn, Amy E., McCollum, Eric D., Monroy, Libny, Moulton, Lawrence H., Mukeshimana, Alexie, Mukhopadhyay, Krishnendu, Naeher, Luke P., Ndagijimana, Florien, Papageorghiou, Aris, Piedrahita, Ricardo, Pillarisetti, Ajay, Puttaswamy, Naveen, Quinn, Ashlinn, Ramakrishnan, Usha, Sambandam, Sankar, Sinharoy, Sheela S., Thangavel, Gurusamy, Underhill, Lindsay J., Waller, Lance A., Wang, Jiantong, Williams, Kendra N., Rosenthal, Joshua P., Checkley, William, Peel, Jennifer L., and HAPIN Investigators
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Adult ,Adolescent ,Infant, Newborn ,General Medicine ,Liquefied Petroleum Gas ,Article ,Young Adult ,Petroleum ,Pregnancy ,Air Pollution, Indoor ,Humans ,Birth Weight ,Female ,Particulate Matter ,Biomass ,Cooking - Abstract
BACKGROUND: Exposure during pregnancy to household air pollution caused by the burning of solid biomass fuel is associated with adverse health outcomes, including low birth weight. Whether the replacement of a biomass cookstove with a liquefied petroleum gas (LPG) cookstove would result in an increase in birth weight is unclear. METHODS: We performed a randomized, controlled trial involving pregnant women (18 to
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- 2022
7. Urinary biomarkers of inorganic arsenic exposure, inorganic arsenic metabolism, and birth weight in Tacna, Peru, 2019
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Fano-Sizgorich, Diego, primary, Gribble, Matthew O., additional, Barr, Dana B., additional, Vasquez-Velasquez, Cinthya, additional, Aguilar, Julio, additional, Ramirez, Claudio, additional, Wickliffe, Jeffrey K., additional, Lichtveld, Maureen, additional, and Gonzales, Gustavo F., additional
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- 2022
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8. Resources and Geographic Access to Care for Severe Pediatric Pneumonia in Four Resource-limited Settings
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Simkovich, Suzanne M., primary, Underhill, Lindsay J., additional, Kirby, Miles A., additional, Crocker, Mary E., additional, Goodman, Dina, additional, McCracken, John P., additional, Thompson, Lisa M., additional, Diaz-Artiga, Anaité, additional, Castañaza-Gonzalez, Adly, additional, Garg, Sarada S., additional, Balakrishnan, Kalpana, additional, Thangavel, Gurusamy, additional, Rosa, Ghislaine, additional, Peel, Jennifer L., additional, Clasen, Thomas F., additional, McCollum, Eric D., additional, Checkley, William, additional, Aravindalochanan, Vigneswari, additional, Barr, Dana B., additional, Burrowes, Vanessa, additional, Campbell, Devan, additional, Canuz, Eduardo, additional, Chang, Howard, additional, Chen, Yunyun, additional, Chiang, Marilú, additional, Clark, Maggie L., additional, Craik, Rachel, additional, Dávila-Román, Victor, additional, Fuentes, Lisa de las, additional, Léon, Oscar De, additional, Dusabimana, Ephrem, additional, Elon, Lisa, additional, Espinoza, Juan Gabriel, additional, Fuentes, Irma S. Pineda, additional, Gupton, Savannah, additional, Hardison, Meghan, additional, Hartinger, Stella, additional, Harvey, Steven A., additional, Hengstermann, Mayari, additional, Herrera, Phabiola, additional, Hossen, Shakir, additional, Howards, Penelope, additional, Jaacks, Lindsay, additional, Jabbarzadeh, Shirin, additional, Johnson, Michael A., additional, Jones, Abigail, additional, Kearns, Katherine, additional, Kremer, Jacob, additional, Laws, Margaret, additional, Lenzen, Patricia M., additional, Liao, Jiawen, additional, Lovvorn, Amy, additional, Majorin, Fiona, additional, McPeek, Julia, additional, Meyers, Rachel M., additional, Miranda, J. Jaime, additional, Mollinedo, Erick, additional, Moulton, Lawrence, additional, Mukhopadhyay, Krishnendu, additional, Naeher, Luke, additional, Nambajimana, Abidan, additional, Ndagijimana, Florien, additional, Nizam, Azhar, additional, Ntivuguruzwa, Jean de Dieu, additional, Papageorghiou, Aris, additional, Piedrahita, Ricardo, additional, Pillarisetti, Ajay, additional, Puttaswamy, Naveen, additional, Puzzolo, Elisa, additional, Quinn, Ashlinn, additional, Rajkumar, Sarah, additional, Ramakrishnan, Usha, additional, Reardon, Davis, additional, Rosenthal, Joshua, additional, Ryan, P. Barry, additional, Sakas, Zoe, additional, Sambandam, Sankar, additional, Sarnat, Jeremy, additional, Sinharoy, Sheela, additional, Smith, Kirk R., additional, Steenland, Kyle, additional, Swearing, Damien, additional, Toenjes, Ashley K., additional, Uwizeyimana, Jean Damascene, additional, Valdes, Viviane, additional, Verma, Amit, additional, Waller, Lance, additional, Warnock, Megan, additional, Williams, Kendra, additional, Ye, Wenlu, additional, and Young, Bonnie, additional
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- 2022
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9. Urinary arsenic species and birth outcomes in Tacna, Peru, 2019: a prospective cohort study.
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Fano-Sizgorich D, Gribble MO, Vásquez-Velásquez C, Ramírez-Atencio C, Aguilar J, Wickliffe JK, Lichtveld MY, Barr DB, and Gonzales GF
- Abstract
Arsenic exposure during pregnancy might affect foetal development. Arsenic metabolism may modulate the potential damage to the fetus. Tacna has the highest arsenic exposure levels in Peru. However, this region also has the highest birth weight in Peru. It is not known if arsenic exposure is affecting maternal-perinatal health in Tacna. This study aimed to evaluate the association between urinary arsenic metabolism and birth outcomes, specifically birth weight and gestational age at birth in Tacna, Peru. A prospective cohort study was conducted, involving 158 pregnant women in Tacna, Peru, during January-November 2019. Participants were enrolled in their second trimester and followed-up until birth. Urine samples were collected in the second and third trimesters. Urine samples were analysed for total arsenic concentration and its species. Generalised estimating equations analysis was used to evaluate the association of interest. Inter-differences in arsenic toxicokinetics, calculated with principal component analysis was included as an interaction term. Analysis was stratified by pregnancy trimester. The median total urinary arsenic concentration was 33.34 μg/L. Inorganic arsenic and dimethylarsinic acid were higher in the second trimester. Dimethylarsinic acid was the predominant component (84.78% of total urinary arsenic). No significant association was found between urinary arsenic exposure and birth weight or gestational age at birth. The association was not affected by arsenic metabolism. Stratified analyses by pregnancy trimester also showed no significant associations. Urinary arsenic was not associated with birth weight, and this null relationship remained unaffected by arsenic toxicokinetic differences reflected in urine., Competing Interests: Dr. Gribble is a current Editor for this journal. All authors declare no conflicts of interest with this work., (© 2024 The Authors.)
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- 2024
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10. Human Immune Cell Epigenomic Signatures in Response to Infectious Diseases and Chemical Exposures.
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Wang W, Hariharan M, Bartlett A, Barragan C, Castanon R, Rothenberg V, Song H, Nery J, Aldridge A, Altshul J, Kenworthy M, Ding W, Liu H, Tian W, Zhou J, Chen H, Wei B, Gündüz IB, Norell T, Broderick TJ, McClain MT, Satterwhite LL, Burke TW, Petzold EA, Shen X, Woods CW, Fowler VG Jr, Ruffin F, Panuwet P, Barr DB, Beare JL, Smith AK, Spurbeck RR, Vangeti S, Ramos I, Nudelman G, Sealfon SC, Castellino F, Walley AM, Evans T, Müller F, Greenleaf WJ, and Ecker JR
- Abstract
Variations in DNA methylation patterns in human tissues have been linked to various environmental exposures and infections. Here, we identified the DNA methylation signatures associated with multiple exposures in nine major immune cell types derived from peripheral blood mononuclear cells (PBMCs) at single-cell resolution. We performed methylome sequencing on 111,180 immune cells obtained from 112 individuals who were exposed to different viruses, bacteria, or chemicals. Our analysis revealed 790,662 differentially methylated regions (DMRs) associated with these exposures, which are mostly individual CpG sites. Additionally, we integrated methylation and ATAC-seq data from same samples and found strong correlations between the two modalities. However, the epigenomic remodeling in these two modalities are complementary. Finally, we identified the minimum set of DMRs that can predict exposures. Overall, our study provides the first comprehensive dataset of single immune cell methylation profiles, along with unique methylation biomarkers for various biological and chemical exposures., Competing Interests: Declaration of Interests Application for patent based on the results from this work has been filed with USPTO with application number US 63/489,546. J.R.E. is a scientific advisor for Zymo Research Inc. and Ionis Pharmaceuticals. W.J.G. is named as an inventor on patents describing ATAC-seq methods. 10X Genomics has licensed intellectual property on which W.J.G. is listed as an inventor. W.J.G. holds options in 10X Genomics and is a consultant for Ultima Genomics and Guardant Health. W.J.G. is a scientific co-founder of Protillion Biosciences. V.G.F. reports personal fees from Novartis, Debiopharm, Genentech, Achaogen, Affinium, Medicines Co., MedImmune, Bayer, Basilea, Affinergy, Janssen, Contrafect, Regeneron, Destiny, Amphliphi Biosciences, Integrated Biotherapeutics; C3J, Armata, Valanbio; Akagera, Aridis, Roche, grants from NIH, MedImmune, Allergan, Pfizer, Advanced Liquid Logics, Theravance, Novartis, Merck; Medical Biosurfaces; Locus; Affinergy; Contrafect; Karius; Genentech, Regeneron, Deep Blue, Basilea, Janssen; royalties from UpToDate, stock options from Valanbio and ArcBio, honoraria from Infectious Diseases of America for his service as Associate Editor of Clinical Infectious Diseases, and a patent for sepsis diagnostics pending. S.C.S. is scientific founder and serve as Chief Scientific Officer of GNOMX Corp.
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- 2023
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