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Your search keyword '"Antonetta C. Houweling"' showing total 4 results
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4 results on '"Antonetta C. Houweling"'

1. Dynamic Contrast-enhanced and Diffusion-weighted Magnetic Resonance Imaging for Response Evaluation After Single-Dose Ablative Neoadjuvant Partial Breast Irradiation

Author

Jeanine E. Vasmel, MD, Maureen L. Groot Koerkamp, MSc, Stefano Mandija, PhD, Wouter B. Veldhuis, PhD, Maaike R. Moman, PhD, Martijn Froeling, PhD, Bas H.M. van der Velden, PhD, Ramona K. Charaghvandi, PhD, Celien P.H. Vreuls, PhD, Paul J. van Diest, PhD, A.M. Gijs van Leeuwen, MD, Joost van Gorp, PhD, Marielle E.P. Philippens, PhD, Bram van Asselen, PhD, Jan J.W. Lagendijk, PhD, Helena M. Verkooijen, PhD, H.J.G. Desirée van den Bongard, PhD, and Antonetta C. Houweling, PhD

Subjects
Medical physics. Medical radiology. Nuclear medicine, R895-920, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Purpose: We aimed to evaluate changes in dynamic contrast-enhanced (DCE) and diffusion-weighted (DW) magnetic resonance imaging (MRI) scans acquired before and after single-dose ablative neoadjuvant partial breast irradiation (NA-PBI), and explore the relation between semiquantitative MRI parameters and radiologic and pathologic responses. Methods and Materials: We analyzed 3.0T DCE and DW-MRI of 36 patients with low-risk breast cancer who were treated with single-dose NA-PBI, followed by breast-conserving surgery 6 or 8 months later. MRI was acquired before NA-PBI and 1 week, 2, 4, and 6 months after NA-PBI. Breast radiologists assessed the radiologic response and breast pathologists scored the pathologic response after surgery. Patients were grouped as either pathologic responders or nonresponders (

Published
2022
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2. Intrafraction motion during radiotherapy of breast tumor, breast tumor bed, and individual axillary lymph nodes on cine magnetic resonance imaging

Author

Maureen L Groot Koerkamp, H.J.G. Desirée van den Bongard, Marielle E.P. Philippens, Femke van der Leij, Stefano Mandija, and Antonetta C Houweling

Subjects
Accelerated partial breast irradiation, Regional lymph nodes, Intrafraction motion, Breast MRI, Supine, Prone, Medical physics. Medical radiology. Nuclear medicine, R895-920, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Background and purpose: In (ultra-)hypofractionation, the contribution of intrafraction motion to treatment accuracy becomes increasingly important. Our purpose was to evaluate intrafraction motion and resulting geometric uncertainties for breast tumor (bed) and individual axillary lymph nodes, and to compare prone and supine position for the breast tumor (bed). Materials and methods: During 1–3 min of free breathing, we acquired transverse/sagittal interleaved 1.5 T cine magnetic resonance imaging (MRI) of the breast tumor (bed) in prone and supine position and coronal/sagittal cine MRI of individual axillary lymph nodes in supine position. A total of 31 prone and 23 supine breast cine MRI (in 23 women) and 52 lymph node cine MRI (in 24 women) were included. Maximum displacement, breathing amplitude, and drift were analyzed using deformable image registration. Geometric uncertainties were calculated for all displacements and for breathing motion only. Results: Median maximum displacements (range over the three orthogonal orientations) were 1.1–1.5 mm for the breast tumor (bed) in prone and 1.8–3.0 mm in supine position, and 2.2–2.4 mm for lymph nodes. Maximum displacements were significantly smaller in prone than in supine position, mainly due to smaller breathing amplitude: 0.6–0.9 mm in prone vs. 0.9–1.4 mm in supine. Systematic and random uncertainties were 0.1–0.4 mm in prone position and 0.2–0.8 mm in supine position for the tumor (bed), and 0.4–0.6 mm for the lymph nodes. Conclusion: Intrafraction motion of breast tumor (bed) and individual lymph nodes was small. Motion of the tumor (bed) was smaller in prone than in supine position.

Published
2022
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3. Prone vs. supine accelerated partial breast irradiation on an MR-Linac: A planning study

Author

Stefano Mandija, Marielle E.P. Philippens, Antonetta C. Houweling, Femke van der Leij, H.J.G. Desiree van den Bongard, Gijsbert H. Bol, V. Scholten, Roel Bouwmans, Maureen L. Groot Koerkamp, Tanja van 't Westeinde, CCA - Imaging and biomarkers, CCA - Cancer Treatment and Quality of Life, and Radiotherapy

Subjects
Supine position, Patient positioning, medicine.medical_treatment, Breast Neoplasms, Prone, Breast cancer, Magnetic resonance imaging, Planning study, Prone Position, Supine Position, medicine, Humans, Radiology, Nuclear Medicine and imaging, MR-Linac, Mr linac, Radiotherapy, medicine.diagnostic_test, business.industry, Radiotherapy Planning, Computer-Assisted, Supine, Partial Breast Irradiation, Radiotherapy Dosage, Hematology, medicine.disease, Accelerated partial breast irradiation, Radiation therapy, Prone position, Oncology, Female, Nuclear medicine, business
Abstract

Background and purpose: Accelerated partial breast irradiation (APBI) may benefit from the MR-Linac for target definition, patient setup, and motion monitoring. In this planning study, we investigated whether prone or supine position is dosimetrically beneficial for APBI on an MR-Linac and we evaluated patient comfort. Materials and methods: Twenty-patients (9 postoperative, 11 preoperative) with a DCIS or breast tumor

Published
2021

4. Dynamic Contrast-enhanced and Diffusion-weighted Magnetic Resonance Imaging for Response Evaluation After Single-Dose Ablative Neoadjuvant Partial Breast Irradiation

Author

Bram van Asselen, A.M. Gijs van Leeuwen, Bas H. M. van der Velden, C. Vreuls, Antonetta C. Houweling, Maaike R. Moman, Joost van Gorp, Stefano Mandija, Martijn Froeling, Helena M. Verkooijen, Wouter B. Veldhuis, Hjg Desirée van den Bongard, Jeanine E. Vasmel, Paul J. van Diest, Jan J W Lagendijk, Maureen L. Groot Koerkamp, Marielle E.P. Philippens, Ramona K. Charaghvandi, Human genetics, CCA - Cancer Treatment and quality of life, CCA - Cancer biology and immunology, Radiotherapy, and CCA - Imaging and biomarkers

Subjects
body regions, Dynamic contrast, Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14], Oncology, business.industry, Ablative case, Partial Breast Irradiation, Medicine, Life Science, Radiology, Nuclear Medicine and imaging, Nuclear medicine, business, Diffusion MRI
Abstract

Contains fulltext : 251425.pdf (Publisher’s version ) (Open Access) PURPOSE: We aimed to evaluate changes in dynamic contrast-enhanced (DCE) and diffusion-weighted (DW) magnetic resonance imaging (MRI) scans acquired before and after single-dose ablative neoadjuvant partial breast irradiation (NA-PBI), and explore the relation between semiquantitative MRI parameters and radiologic and pathologic responses. METHODS AND MATERIALS: We analyzed 3.0T DCE and DW-MRI of 36 patients with low-risk breast cancer who were treated with single-dose NA-PBI, followed by breast-conserving surgery 6 or 8 months later. MRI was acquired before NA-PBI and 1 week, 2, 4, and 6 months after NA-PBI. Breast radiologists assessed the radiologic response and breast pathologists scored the pathologic response after surgery. Patients were grouped as either pathologic responders or nonresponders (

Published
2022

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