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Your search keyword '"André, Sabine"' showing total 13 results
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13 results on '"André, Sabine"'

1. Targeting osteoarthritis-associated galectins and an induced effector class by a ditopic bifunctional reagent: Impact of its glycan part on binding measured in the tissue context

Author

Manning, Joachim C., Baldoneschi, Veronica, Romero-Hernández, Laura L., Pichler, Katharina M., GarcÍa Caballero, Gabriel, André, Sabine, Kutzner, Tanja J., Ludwig, Anna-Kristin, Zullo, Valerio, Richichi, Barbara, Windhager, Reinhard, Kaltner, Herbert, Toegel, Stefan, Gabius, Hans-Joachim, Murphy, Paul V., and Nativi, Cristina

Published
2022
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2. Galectin-9 as a Potential Modulator of Lymphocyte Adhesion to Endothelium via Binding to Blood Group H Glycan

Author

Rapoport, Eugenia M., primary, Ryzhov, Ivan M., additional, Slivka, Ekaterina V., additional, Korchagina, Elena Yu., additional, Popova, Inna S., additional, Khaidukov, Sergey V., additional, André, Sabine, additional, Kaltner, Herbert, additional, Gabius, Hans-J., additional, Henry, Stephen, additional, and Bovin, Nicolai V., additional

Published
2023
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3. Supplementary Video 4 from Galectin-1 Drives Pancreatic Carcinogenesis through Stroma Remodeling and Hedgehog Signaling Activation

Author

Martínez-Bosch, Neus, primary, Fernández-Barrena, Maite G., primary, Moreno, Mireia, primary, Ortiz-Zapater, Elena, primary, Munné-Collado, Jessica, primary, Iglesias, Mar, primary, André, Sabine, primary, Gabius, Hans-Joachim, primary, Hwang, Rosa F., primary, Poirier, Françoise, primary, Navas, Carolina, primary, Guerra, Carmen, primary, Fernández-Zapico, Martin E., primary, and Navarro, Pilar, primary

Published
2023
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4. Supplementary Video 5 from Galectin-1 Drives Pancreatic Carcinogenesis through Stroma Remodeling and Hedgehog Signaling Activation

Author

Martínez-Bosch, Neus, primary, Fernández-Barrena, Maite G., primary, Moreno, Mireia, primary, Ortiz-Zapater, Elena, primary, Munné-Collado, Jessica, primary, Iglesias, Mar, primary, André, Sabine, primary, Gabius, Hans-Joachim, primary, Hwang, Rosa F., primary, Poirier, Françoise, primary, Navas, Carolina, primary, Guerra, Carmen, primary, Fernández-Zapico, Martin E., primary, and Navarro, Pilar, primary

Published
2023
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5. Supplementary Video 6 from Galectin-1 Drives Pancreatic Carcinogenesis through Stroma Remodeling and Hedgehog Signaling Activation

Author

Martínez-Bosch, Neus, primary, Fernández-Barrena, Maite G., primary, Moreno, Mireia, primary, Ortiz-Zapater, Elena, primary, Munné-Collado, Jessica, primary, Iglesias, Mar, primary, André, Sabine, primary, Gabius, Hans-Joachim, primary, Hwang, Rosa F., primary, Poirier, Françoise, primary, Navas, Carolina, primary, Guerra, Carmen, primary, Fernández-Zapico, Martin E., primary, and Navarro, Pilar, primary

Published
2023
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6. Supplementary Table 2 from Galectin-1 Drives Pancreatic Carcinogenesis through Stroma Remodeling and Hedgehog Signaling Activation

Author

Martínez-Bosch, Neus, primary, Fernández-Barrena, Maite G., primary, Moreno, Mireia, primary, Ortiz-Zapater, Elena, primary, Munné-Collado, Jessica, primary, Iglesias, Mar, primary, André, Sabine, primary, Gabius, Hans-Joachim, primary, Hwang, Rosa F., primary, Poirier, Françoise, primary, Navas, Carolina, primary, Guerra, Carmen, primary, Fernández-Zapico, Martin E., primary, and Navarro, Pilar, primary

Published
2023
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7. Supplementary Video 3 from Galectin-1 Drives Pancreatic Carcinogenesis through Stroma Remodeling and Hedgehog Signaling Activation

Author

Martínez-Bosch, Neus, primary, Fernández-Barrena, Maite G., primary, Moreno, Mireia, primary, Ortiz-Zapater, Elena, primary, Munné-Collado, Jessica, primary, Iglesias, Mar, primary, André, Sabine, primary, Gabius, Hans-Joachim, primary, Hwang, Rosa F., primary, Poirier, Françoise, primary, Navas, Carolina, primary, Guerra, Carmen, primary, Fernández-Zapico, Martin E., primary, and Navarro, Pilar, primary

Published
2023
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8. Supplementary Video 2 from Galectin-1 Drives Pancreatic Carcinogenesis through Stroma Remodeling and Hedgehog Signaling Activation

Author

Martínez-Bosch, Neus, primary, Fernández-Barrena, Maite G., primary, Moreno, Mireia, primary, Ortiz-Zapater, Elena, primary, Munné-Collado, Jessica, primary, Iglesias, Mar, primary, André, Sabine, primary, Gabius, Hans-Joachim, primary, Hwang, Rosa F., primary, Poirier, Françoise, primary, Navas, Carolina, primary, Guerra, Carmen, primary, Fernández-Zapico, Martin E., primary, and Navarro, Pilar, primary

Published
2023
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9. Supplementary Video 1 from Galectin-1 Drives Pancreatic Carcinogenesis through Stroma Remodeling and Hedgehog Signaling Activation

Author

Martínez-Bosch, Neus, primary, Fernández-Barrena, Maite G., primary, Moreno, Mireia, primary, Ortiz-Zapater, Elena, primary, Munné-Collado, Jessica, primary, Iglesias, Mar, primary, André, Sabine, primary, Gabius, Hans-Joachim, primary, Hwang, Rosa F., primary, Poirier, Françoise, primary, Navas, Carolina, primary, Guerra, Carmen, primary, Fernández-Zapico, Martin E., primary, and Navarro, Pilar, primary

Published
2023
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10. Supplementary Results, Materials and Methods, Movie Legends, Figures 1 - 7, Tables 1, 3 - 4 from Galectin-1 Drives Pancreatic Carcinogenesis through Stroma Remodeling and Hedgehog Signaling Activation

Author

Martínez-Bosch, Neus, primary, Fernández-Barrena, Maite G., primary, Moreno, Mireia, primary, Ortiz-Zapater, Elena, primary, Munné-Collado, Jessica, primary, Iglesias, Mar, primary, André, Sabine, primary, Gabius, Hans-Joachim, primary, Hwang, Rosa F., primary, Poirier, Françoise, primary, Navas, Carolina, primary, Guerra, Carmen, primary, Fernández-Zapico, Martin E., primary, and Navarro, Pilar, primary

Published
2023
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11. Data from Galectin-1 Drives Pancreatic Carcinogenesis through Stroma Remodeling and Hedgehog Signaling Activation

Author

Martínez-Bosch, Neus, primary, Fernández-Barrena, Maite G., primary, Moreno, Mireia, primary, Ortiz-Zapater, Elena, primary, Munné-Collado, Jessica, primary, Iglesias, Mar, primary, André, Sabine, primary, Gabius, Hans-Joachim, primary, Hwang, Rosa F., primary, Poirier, Françoise, primary, Navas, Carolina, primary, Guerra, Carmen, primary, Fernández-Zapico, Martin E., primary, and Navarro, Pilar, primary

Published
2023
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13. Synthesis and Thermodynamic Evaluation of Sialyl-Tn MUC1 Glycopeptides Binding to Macrophage Galactose-Type Lectin.

Author

Ayyalasomayajula R, Boneva I, Ormaza D, Whyte A Jr, Farook K, Gorlin Z, Yancey E, André S, Kaltner H, and Cudic M

Abstract

Interactions between the tumor-associated carbohydrate antigens of Mucin 1 (MUC1) and the carbohydrate-binding proteins, lectins, often lead to the creation of a pro-tumor microenvironment favoring tumor initiation, progression, metastasis, and immune evasion. Macrophage galactose binding lectin (MGL) is a C-type lectin receptor found on antigen-presenting cells that facilitates the uptake of carbohydrate antigens for antigen presentation, modulating the immune response homeostasis, autoimmunity, and cancer. Considering the crucial role of tumor-associated forms of MUC1 and MGL in tumor immunology, a thorough understanding of their binding interaction is essential for it to be exploited for cancer vaccine strategies. The synthesis of MUC1 glycopeptide models carrying a single or multiple Tn and/or sialyl-Tn antigen(s) is described. A novel approach for the sialyl-Tn threonine building block suitable for the solid phase peptide synthesis was developed. The thermodynamic profile of the binding interaction between the human MGL and MUC1 glycopeptide models was analyzed using isothermal titration calorimetry. The measured dissociation constants for the sialyl-Tn-bearing peptide epitopes were consistently lower compared to the Tn antigen and ranged from 10 μM for mono- to 1 μM for triglycosylated MUC1 peptide, respectively. All studied interactions, regardless of the glycan's site of attachment or density, exhibited enthalpy-driven thermodynamics., (© 2024 Wiley-VCH GmbH.)

Published
2024
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