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9 results on '"Alessandro, Bulfone"'

1. Supplementary Figure 4 from Gene Signatures Associated with Mouse Postnatal Hindbrain Neural Stem Cells and Medulloblastoma Cancer Stem Cells Identify Novel Molecular Mediators and Predict Human Medulloblastoma Molecular Classification

Author

Rossella Galli, Pietro Luigi Poliani, Gian Giacomo Consalez, Ferdinando Rossi, Paola Rossi, Alessandro Bulfone, Lorenzo Piemonti, Letterio Salvatore Politi, Lucia Sergi Sergi, Alessandra Di Gregorio, Raffaella Melzi, Federico Brandalise, Valeria Barili, Laura Croci, Ketty Leto, Barbara Cipelletti, Manuela Cominelli, Mauro Pala, and Daniela Corno

Abstract

PDF file - 213K, Gene signatures distinguishing the different MB CSC populations segregate distinct human MB molecular subgroups, with MB1_EXCLUSIVE gene signature distinguishing the WNT molecular subgroup

Published
2023
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2. Supplementary Figure 2 from Gene Signatures Associated with Mouse Postnatal Hindbrain Neural Stem Cells and Medulloblastoma Cancer Stem Cells Identify Novel Molecular Mediators and Predict Human Medulloblastoma Molecular Classification

Author

Rossella Galli, Pietro Luigi Poliani, Gian Giacomo Consalez, Ferdinando Rossi, Paola Rossi, Alessandro Bulfone, Lorenzo Piemonti, Letterio Salvatore Politi, Lucia Sergi Sergi, Alessandra Di Gregorio, Raffaella Melzi, Federico Brandalise, Valeria Barili, Laura Croci, Ketty Leto, Barbara Cipelletti, Manuela Cominelli, Mauro Pala, and Daniela Corno

Abstract

PDF file - 183K, Long term-cultured hindbrain- and forebrain-derived NSCs are Sonic Hedgehog (Shh) pathway-independent, as cyclopamine treatment negatively affects the survival/proliferation of short-term cultured but not of long term-cultured NSCs

Published
2023
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3. Supplementary Figure 7 from Gene Signatures Associated with Mouse Postnatal Hindbrain Neural Stem Cells and Medulloblastoma Cancer Stem Cells Identify Novel Molecular Mediators and Predict Human Medulloblastoma Molecular Classification

Author

Rossella Galli, Pietro Luigi Poliani, Gian Giacomo Consalez, Ferdinando Rossi, Paola Rossi, Alessandro Bulfone, Lorenzo Piemonti, Letterio Salvatore Politi, Lucia Sergi Sergi, Alessandra Di Gregorio, Raffaella Melzi, Federico Brandalise, Valeria Barili, Laura Croci, Ketty Leto, Barbara Cipelletti, Manuela Cominelli, Mauro Pala, and Daniela Corno

Abstract

PDF file - 155K, Enforced expression of Ebf3 in CB WM and SVZ NSCs results in premature neuronal differentiation, under proliferative and differentiative conditions

Published
2023
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4. Supplementary Figure 3 from Gene Signatures Associated with Mouse Postnatal Hindbrain Neural Stem Cells and Medulloblastoma Cancer Stem Cells Identify Novel Molecular Mediators and Predict Human Medulloblastoma Molecular Classification

Author

Rossella Galli, Pietro Luigi Poliani, Gian Giacomo Consalez, Ferdinando Rossi, Paola Rossi, Alessandro Bulfone, Lorenzo Piemonti, Letterio Salvatore Politi, Lucia Sergi Sergi, Alessandra Di Gregorio, Raffaella Melzi, Federico Brandalise, Valeria Barili, Laura Croci, Ketty Leto, Barbara Cipelletti, Manuela Cominelli, Mauro Pala, and Daniela Corno

Abstract

PDF file - 157K, MB CSC lines are Sonic Hedgehog (Shh) pathway-independent, as their survival/proliferation is not affected by cyclopamine treatment and Smo silencing

Published
2023
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5. Supplementary Methods from Gene Signatures Associated with Mouse Postnatal Hindbrain Neural Stem Cells and Medulloblastoma Cancer Stem Cells Identify Novel Molecular Mediators and Predict Human Medulloblastoma Molecular Classification

Author

Rossella Galli, Pietro Luigi Poliani, Gian Giacomo Consalez, Ferdinando Rossi, Paola Rossi, Alessandro Bulfone, Lorenzo Piemonti, Letterio Salvatore Politi, Lucia Sergi Sergi, Alessandra Di Gregorio, Raffaella Melzi, Federico Brandalise, Valeria Barili, Laura Croci, Ketty Leto, Barbara Cipelletti, Manuela Cominelli, Mauro Pala, and Daniela Corno

Abstract

PDF file - 104K, Details on experimental and bioinformatics procedures.

Published
2023
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6. Supplementary Tables 1-5 from Gene Signatures Associated with Mouse Postnatal Hindbrain Neural Stem Cells and Medulloblastoma Cancer Stem Cells Identify Novel Molecular Mediators and Predict Human Medulloblastoma Molecular Classification

Author

Rossella Galli, Pietro Luigi Poliani, Gian Giacomo Consalez, Ferdinando Rossi, Paola Rossi, Alessandro Bulfone, Lorenzo Piemonti, Letterio Salvatore Politi, Lucia Sergi Sergi, Alessandra Di Gregorio, Raffaella Melzi, Federico Brandalise, Valeria Barili, Laura Croci, Ketty Leto, Barbara Cipelletti, Manuela Cominelli, Mauro Pala, and Daniela Corno

Abstract

PDF file - 134K, Table S1 A. Lineage-specific differentiation of region-specific clonally derived NSCs is summarized as frequency of neurons, astrocytes and oligodendrocytes. B. Electrophysiological characteristics of neurons derived from the differentiation of region-specific NSCs. C. Analysis of the engraftment of region-specific clonally derived NSCs after transplantation in the early postnatal mouse cerebellum. Table S2 - Statistical analysis of GSEA for gene signatures generated by DEGs up regulated in hindbrain (CB/IVv) or forebrain (SVZ) NSCs. Table S3 - Lineage-specific differentiation of clonally derived MB CSCs is summarized as frequency of neuron-, astrocyte- and oligodendrocyte-like cells. Table S4 - Statistical analysis of GSEA for gene signatures generated by DEGs up regulated in tumorigenic Ptch+/- p53-/- MB CSCs vs. hindbrain NSCs (MB1_EXCLUSIVE), in non-tumorigenic Ptch+/- p53+/+ MB CSCs vs. hindbrain NSCs (MB2_EXCLUSIVE), and commonly expressed in both tumorigenic and non-tumorigenic CSCs vs. hindbrain NSCs (MB1_MB2 COMMON). Table S5 - Expression of EBF proteins in a collection of 33 human MB specimens as determined by immunohistochemistry.

Published
2023
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7. Supplementary Figure 6 from Gene Signatures Associated with Mouse Postnatal Hindbrain Neural Stem Cells and Medulloblastoma Cancer Stem Cells Identify Novel Molecular Mediators and Predict Human Medulloblastoma Molecular Classification

Author

Rossella Galli, Pietro Luigi Poliani, Gian Giacomo Consalez, Ferdinando Rossi, Paola Rossi, Alessandro Bulfone, Lorenzo Piemonti, Letterio Salvatore Politi, Lucia Sergi Sergi, Alessandra Di Gregorio, Raffaella Melzi, Federico Brandalise, Valeria Barili, Laura Croci, Ketty Leto, Barbara Cipelletti, Manuela Cominelli, Mauro Pala, and Daniela Corno

Abstract

PDF file - 130K, EBF3 expression can be retrieved in silico in human MBs by exploiting publicly available human data sets

Published
2023
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8. Supplementary Figure 1 from Gene Signatures Associated with Mouse Postnatal Hindbrain Neural Stem Cells and Medulloblastoma Cancer Stem Cells Identify Novel Molecular Mediators and Predict Human Medulloblastoma Molecular Classification

Author

Rossella Galli, Pietro Luigi Poliani, Gian Giacomo Consalez, Ferdinando Rossi, Paola Rossi, Alessandro Bulfone, Lorenzo Piemonti, Letterio Salvatore Politi, Lucia Sergi Sergi, Alessandra Di Gregorio, Raffaella Melzi, Federico Brandalise, Valeria Barili, Laura Croci, Ketty Leto, Barbara Cipelletti, Manuela Cominelli, Mauro Pala, and Daniela Corno

Abstract

PDF file - 132K, The gene signature containing the 297 genes differentially expressed between hindbrain- vs. forebrain-derived NSCs distinguishes the SHH molecular subgroup of human MBs

Published
2023
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9. Supplementary Figures 1-9, Tables 1-4, Methods and Materials from Epidermal Growth Factor Receptor Expression Identifies Functionally and Molecularly Distinct Tumor-Initiating Cells in Human Glioblastoma Multiforme and Is Required for Gliomagenesis

Author

Rossella Galli, Pietro L. Poliani, Alessandro Bulfone, Michele De Palma, Andrea Falini, Lucia Sergi Sergi, Alberto Franzin, Manuela Cominelli, Mauro Pala, Letterio S. Politi, and Stefania Mazzoleni

Abstract

Supplementary Figures 1-9, Tables 1-4, Methods and Materials from Epidermal Growth Factor Receptor Expression Identifies Functionally and Molecularly Distinct Tumor-Initiating Cells in Human Glioblastoma Multiforme and Is Required for Gliomagenesis

Published
2023
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