Search

Your search keyword '"Aitken, Robert J."' showing total 21 results
Start Over Author "Aitken, Robert J." Publication Year Range Last 3 years
21 results on '"Aitken, Robert J."'

1. Governance of advanced materials: Shaping a safe and sustainable future

Author

Groenewold, Monique, Bleeker, Eric A.J., Noorlander, Cornelle W., Sips, Adriënne J.A.M., van der Zee, Margriet, Aitken, Robert J., Baker, James H., Bakker, Martine I., Bouman, Evert A., Doak, Shareen H., Drobne, Damjana, Dumit, Verónica I., Florin, Marie-Valentine, Fransman, Wouter, Gonzalez, Mar M., Heunisch, Elisabeth, Isigonis, Panagiotis, Jeliazkova, Nina, Jensen, Keld Alstrup, Kuhlbusch, Thomas, Lynch, Iseult, Morrison, Mark, Porcari, Andrea, Rodríguez-Llopis, Isabel, Pozuelo, Blanca M., Resch, Susanne, Säämänen, Arto J., Serchi, Tommaso, Soeteman-Hernandez, Lya G., Willighagen, Egon, Dusinska, Maria, and Scott-Fordsmand, Janeck J.

Published
2024
Full Text
View/download PDF

2. Enhanced Recovery After Surgery (ERAS®) Society Consensus Guidelines for Emergency Laparotomy Part 3: Organizational Aspects and General Considerations for Management of the Emergency Laparotomy Patient

Author

Peden, Carol J., Aggarwal, Geeta, Aitken, Robert J., Anderson, Iain D., Balfour, Angie, Foss, Nicolai Bang, Cooper, Zara, Dhesi, Jugdeep K., French, W. Brenton, Grant, Michael C., Hammarqvist, Folke, Hare, Sarah P., Havens, Joaquim M., Holena, Daniel N., Hübner, Martin, Johnston, Carolyn, Kim, Jeniffer S., Lees, Nicholas P., Ljungqvist, Olle, Lobo, Dileep N., Mohseni, Shahin, Ordoñez, Carlos A., Quiney, Nial, Sharoky, Catherine, Urman, Richard D., Wick, Elizabeth, Wu, Christopher L., Young-Fadok, Tonia, and Scott, Michael J.

Published
2023
Full Text
View/download PDF

3. Consensus Guidelines for Perioperative Care for Emergency Laparotomy Enhanced Recovery After Surgery (ERAS®) Society Recommendations Part 2—Emergency Laparotomy: Intra- and Postoperative Care

Author

Scott, Michael J., Aggarwal, Geeta, Aitken, Robert J., Anderson, Iain D., Balfour, Angie, Foss, Nicolai Bang, Cooper, Zara, Dhesi, Jugdeep K., French, W. Brenton, Grant, Michael C., Hammarqvist, Folke, Hare, Sarah P., Havens, Joaquim M., Holena, Daniel N., Hübner, Martin, Johnston, Carolyn, Kim, Jeniffer S., Lees, Nicholas P., Ljungqvist, Olle, Lobo, Dileep N., Mohseni, Shahin, Ordoñez, Carlos A., Quiney, Nial, Sharoky, Catherine, Urman, Richard D., Wick, Elizabeth, Wu, Christopher L., Young-Fadok, Tonia, and Peden, Carol J.

Published
2023
Full Text
View/download PDF

6. The effects of oxidative stress and intracellular calcium on mitochondrial permeability transition pore formation in equine spermatozoa.

Author

Gibb, Zamira, Aitken, Robert J., Sheridan, Alecia R., Holt, Brandan, Waugh, Stephanie, and Swegen, Aleona

Subjects
*SPERMATOGENESIS, *HOMEOSTASIS, *SPERMATOZOA, *INTRACELLULAR calcium, *OXIDATIVE stress, *PERMEABILITY, *REACTIVE oxygen species
Abstract

The in vitro storage of stallion spermatozoa for use in artificial insemination leads to oxidative stress and imbalances in calcium homeostasis that trigger the formation of the mitochondrial permeability transition pore (mPTP), resulting in premature cell death. However, little is understood about the dynamics and the role of mPTP formation in mammalian spermatozoa. Here, we identify an important role for mPTP in stallion sperm Ca2+ homeostasis. We show that stallion spermatozoa do not exhibit "classical" features of mPTP; specifically, they are resistant to cyclosporin A‐mediated inhibition of mPTP formation, and they do not require exogenous Ca2+ to form the mPTP. However, chelation of endogenous Ca2+ prevented mPTP formation, indicating a role for intracellular Ca2+ in this process. Furthermore, our findings suggest that this cell type can mobilize intracellular Ca2+ stores to form the mPTP in response to low Ca2+ environments and that under oxidative stress conditions, mPTP formation preceded a measurable increase in intracellular Ca2+, and vice versa. Contrary to previous work that identified mitochondrial membrane potential (MMP) as a proxy for mPTP formation, here we show that a loss of MMP can occur independently of mPTP formation, and thus MMP is not an appropriate proxy for the detection of mPTP formation. In conclusion, the mPTP plays a crucial role in maintaining Ca2+ and reactive oxygen species homeostasis in stallion spermatozoa, serving as an important regulatory mechanism for normal sperm function, thereby contraindicating the in vitro pharmacological inhibition of mPTP formation to enhance sperm longevity. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

8. Sperm chromatin structure assay (SCSA®) and flow cytometry-assisted TUNEL assay provide a concordant assessment of sperm DNA fragmentation as a function of age in a large cohort of approximately 10,000 patients.

Author

Behdarvandian, Paria, Nasr-Esfahani, Ali, Tavalaee, Marziyeh, Pashaei, Kosar, Naderi, Nushin, Darmishonnejad, Zahra, Hallak, Jorge, Aitken, Robert J., Gharagozloo, Parviz, Drevet, Joël R., and Nasr-Esfahani, Mohammad Hossein

Subjects
SPERMATOZOA, DNA structure, REPRODUCTIVE technology, CHROMATIN, NUCLEAR DNA, Y chromosome, MALE infertility
Abstract

Copyright of Basic & Clinical Andrology is the property of BioMed Central and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2023
Full Text
View/download PDF

10. Consensus Guidelines for Perioperative Care for Emergency Laparotomy Enhanced Recovery After Surgery (ERAS®) Society Recommendations Part 2—Emergency Laparotomy: Intra- and Postoperative Care.

Author

Scott, Michael J., Aggarwal, Geeta, Aitken, Robert J., Anderson, Iain D., Balfour, Angie, Foss, Nicolai Bang, Cooper, Zara, Dhesi, Jugdeep K., French, W. Brenton, Grant, Michael C., Hammarqvist, Folke, Hare, Sarah P., Havens, Joaquim M., Holena, Daniel N., Hübner, Martin, Johnston, Carolyn, Kim, Jeniffer S., Lees, Nicholas P., Ljungqvist, Olle, and Lobo, Dileep N.

Subjects
PERIOPERATIVE care, POSTOPERATIVE care, SURGERY, ENHANCED recovery after surgery protocol, ABDOMINAL surgery, ELECTIVE surgery
Abstract

Background: This is Part 2 of the first consensus guidelines for optimal care of patients undergoing emergency laparotomy (EL) using an Enhanced Recovery After Surgery (ERAS) approach. This paper addresses intra- and postoperative aspects of care. Methods: Experts in aspects of management of high-risk and emergency general surgical patients were invited to contribute by the International ERAS® Society. PubMed, Cochrane, Embase, and Medline database searches were performed for ERAS elements and relevant specific topics. Studies on each item were selected with particular attention to randomized clinical trials, systematic reviews, meta-analyses, and large cohort studies and reviewed and graded using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) system. Recommendations were made on the best level of evidence, or extrapolation from studies on elective patients when appropriate. A modified Delphi method was used to validate final recommendations. Some ERAS® components covered in other guideline papers are outlined only briefly, with the bulk of the text focusing on key areas pertaining specifically to EL. Results: Twenty-three components of intraoperative and postoperative care were defined. Consensus was reached after three rounds of a modified Delphi Process. Conclusions: These guidelines are based on best available evidence for an ERAS® approach to patients undergoing EL. These guidelines are not exhaustive but pull together evidence on important components of care for this high-risk patient population. As much of the evidence is extrapolated from elective surgery or emergency general surgery (not specifically laparotomy), many of the components need further evaluation in future studies. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

14. Standards in semen examination: publishing reproducible and reliable data based on high-quality methodology

Author

Björndahl, Lars, primary, Barratt, Christopher L R, additional, Mortimer, David, additional, Agarwal, Ashok, additional, Aitken, Robert J, additional, Alvarez, Juan G, additional, Aneck-Hahn, Natalie, additional, Arver, Stefan, additional, Baldi, Elisabetta, additional, Bassas, Lluís, additional, Boitrelle, Florence, additional, Bornman, Riana, additional, Carrell, Douglas T, additional, Castilla, José A, additional, Cerezo Parra, Gerardo, additional, Check, Jerome H, additional, Cuasnicu, Patricia S, additional, Darney, Sally Perreault, additional, de Jager, Christiaan, additional, De Jonge, Christopher J, additional, Drevet, Joël R, additional, Drobnis, Erma Z, additional, Du Plessis, Stefan S, additional, Eisenberg, Michael L, additional, Esteves, Sandro C, additional, Evgeni, Evangelini A, additional, Ferlin, Alberto, additional, Garrido, Nicolas, additional, Giwercman, Aleksander, additional, Goovaerts, Ilse G F, additional, Haugen, Trine B, additional, Henkel, Ralf, additional, Henningsohn, Lars, additional, Hofmann, Marie-Claude, additional, Hotaling, James M, additional, Jedrzejczak, Piotr, additional, Jouannet, Pierre, additional, Jørgensen, Niels, additional, Kirkman Brown, Jackson C, additional, Krausz, Csilla, additional, Kurpisz, Maciej, additional, Kvist, Ulrik, additional, Lamb, Dolores J, additional, Levine, Hagai, additional, Loveland, Kate L, additional, McLachlan, Robert I, additional, Mahran, Ali, additional, Maree, Liana, additional, Martins da Silva, Sarah, additional, Mbizvo, Michael T, additional, Meinhardt, Andreas, additional, Menkveld, Roelof, additional, Mortimer, Sharon T, additional, Moskovtsev, Sergey, additional, Muller, Charles H, additional, Munuce, Maria José, additional, Muratori, Monica, additional, Niederberger, Craig, additional, O’Flaherty, Cristian, additional, Oliva, Rafael, additional, Ombelet, Willem, additional, Pacey, Allan A, additional, Palladino, Michael A, additional, Ramasamy, Ranjith, additional, Ramos, Liliana, additional, Rives, Nathalie, additional, Roldan, Eduardo Rs, additional, Rothmann, Susan, additional, Sakkas, Denny, additional, Salonia, Andrea, additional, Sánchez-Pozo, Maria Cristina, additional, Sapiro, Rosanna, additional, Schlatt, Stefan, additional, Schlegel, Peter N, additional, Schuppe, Hans-Christian, additional, Shah, Rupin, additional, Skakkebæk, Niels E, additional, Teerds, Katja, additional, Toskin, Igor, additional, Tournaye, Herman, additional, Turek, Paul J, additional, van der Horst, Gerhard, additional, Vazquez-Levin, Monica, additional, Wang, Christina, additional, Wetzels, Alex, additional, Zeginiadou, Theodosia, additional, and Zini, Armand, additional

Published
2022
Full Text
View/download PDF

20. Sperm telomeres, oxidative stress, and infertility.

Author

Moazamian, Aron, Gharagozloo, Parviz, Aitken, Robert J., and Drevet, Joël R.

Subjects
OXIDATIVE stress, MALE reproductive organs, MALE reproductive health, SPERMATOZOA, INFERTILITY, TELOMERES
Abstract

The maintenance of redox balance in the male reproductive tract is critical to sperm health and function. Physiological levels of reactive oxygen species (ROS) promote sperm capacitation, while excess ROS exposure, or depleted antioxidant defenses, yields a state of oxidative stress which disrupts their fertilizing capacity and DNA structural integrity. The guanine moiety is the most readily oxidized of the four DNA bases and gets converted to the mutagenic lesion 8-hydroxydeoxyguanosine (8-OHdG). Numerous studies have also confirmed oxidative stress as a driving factor behind accelerated telomere shortening and dysfunction. Although a clear consensus has not been reached, clinical studies also appear to associate telomere integrity with fertility outcomes in the assisted reproductive technology setting. Intriguingly, while sperm cellular and molecular characteristics make them more susceptible to oxidative insult than any other cell type, they are also the only cell type in which telomere lengthening accompanies aging. This article focuses on the oxidative stress response pathways to propose a mechanism for the explanation of this apparent paradox. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

21. Standards in semen examination: publishing reproducible and reliable data based on high-quality methodology

Author

Lars Björndahl, Christopher L R Barratt, David Mortimer, Ashok Agarwal, Robert J Aitken, Juan G Alvarez, Natalie Aneck-Hahn, Stefan Arver, Elisabetta Baldi, Lluís Bassas, Florence Boitrelle, Riana Bornman, Douglas T Carrell, José A Castilla, Gerardo Cerezo Parra, Jerome H Check, Patricia S Cuasnicu, Sally Perreault Darney, Christiaan de Jager, Christopher J De Jonge, Joël R Drevet, Erma Z Drobnis, Stefan S Du Plessis, Michael L Eisenberg, Sandro C Esteves, Evangelini A Evgeni, Alberto Ferlin, Nicolas Garrido, Aleksander Giwercman, Ilse G F Goovaerts, Trine B Haugen, Ralf Henkel, Lars Henningsohn, Marie-Claude Hofmann, James M Hotaling, Piotr Jedrzejczak, Pierre Jouannet, Niels Jørgensen, Jackson C Kirkman Brown, Csilla Krausz, Maciej Kurpisz, Ulrik Kvist, Dolores J Lamb, Hagai Levine, Kate L Loveland, Robert I McLachlan, Ali Mahran, Liana Maree, Sarah Martins da Silva, Michael T Mbizvo, Andreas Meinhardt, Roelof Menkveld, Sharon T Mortimer, Sergey Moskovtsev, Charles H Muller, Maria José Munuce, Monica Muratori, Craig Niederberger, Cristian O’Flaherty, Rafael Oliva, Willem Ombelet, Allan A Pacey, Michael A Palladino, Ranjith Ramasamy, Liliana Ramos, Nathalie Rives, Eduardo Rs Roldan, Susan Rothmann, Denny Sakkas, Andrea Salonia, Maria Cristina Sánchez-Pozo, Rosanna Sapiro, Stefan Schlatt, Peter N Schlegel, Hans-Christian Schuppe, Rupin Shah, Niels E Skakkebæk, Katja Teerds, Igor Toskin, Herman Tournaye, Paul J Turek, Gerhard van der Horst, Monica Vazquez-Levin, Christina Wang, Alex Wetzels, Theodosia Zeginiadou, Armand Zini, Faculty of Medicine and Pharmacy, Clinical sciences, Biology of the Testis, Centre for Reproductive Medicine - Gynaecology, Génétique, Reproduction et Développement (GReD), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Centre National de la Recherche Scientifique (CNRS), CHU Rouen, Normandie Université (NU), UNIROUEN - UFR Santé (UNIROUEN UFR Santé), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU), Neuroendocrine, Endocrine and Germinal Differentiation Communication (NorDic), Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Björndahl, L, Barratt, Clr, Mortimer, D, Agarwal, A, Aitken, Rj, Alvarez, Jg, Aneck-Hahn, N, Arver, S, Baldi, E, Bassas, L, Boitrelle, F, Bornman, R, Carrell, Dt, Castilla, Ja, Cerezo Parra, G, Check, Jh, Cuasnicu, P, Darney, Sp, de Jager, C, De Jonge, Cj, Drevet, Jr, Drobnis, Ez, Du Plessis, S, Eisenberg, Ml, Esteves, Sc, Evgeni, Ea, Ferlin, A, Garrido, N, Giwercman, A, Goovaerts, Igf, Haugen, Tb, Henkel, R, Henningsohn, L, Hofmann, Mc, Hotaling, Jm, Jedrzejczak, P, Jouannet, P, Jørgensen, N, Kirkman Brown, Jc, Krausz, C, Kurpisz, M, Kvist, U, Lamb, Dj, Levine, H, Loveland, Kl, Mclachlan, Ri, Mahran, A, Maree, L, Martins da Silva, S, Mbizvo, Mt, Meinhardt, A, Menkveld, R, Mortimer, St, Moskovtsev, S, Muller, Ch, Munuce, Mj, Muratori, M, Niederberger, C, O'Flaherty, C, Oliva, R, Ombelet, W, Pacey, Aa, Palladino, Ma, Ramasamy, R, Ramos, L, Rives, N, Roldan, Er, Rothmann, S, Sakkas, D, Salonia, A, Sánchez-Pozo, Mc, Sapiro, R, Schlatt, S, Schlegel, Pn, Schuppe, Hc, Shah, R, Skakkebæk, Ne, Teerds, K, Toskin, I, Tournaye, H, Turek, Pj, van der Horst, G, Vazquez-Levin, M, Wang, C, Wetzels, A, Zeginiadou, T, Zini, A., Pacey, Allan/0000-0002-4387-8871, Arver, Stefan/0000-0002-2925-355X, Mortimer, David/0000-0002-0638-2893, Barratt, christopher/0000-0003-0062-9979, Kirkman-Brown, Jackson, C/0000-0003-2833-8970, Bjorndahl, Lars/0000-0002-4709-5807, Baldi, Elisabetta/0000-0003-1808-3097, Aitken, Robert John/0000-0002-9152-156X, Bjorndahl, Lars, Barratt, Christopher L. R., Mortimer, David, Agarwal, Ashok, Aitken, Robert J., Alvarez, Juan G., Aneck-Hahn, Natalie, Arver, Stefan, Baldi, Elisabetta, Bassas, Lluis, Boitrelle, Florence, Bornman, Riana, Carrell, Douglas T., Castilla, Jose A., Cerezo Parra, Gerardo, Check, Jerome H., Cuasnicu, Patricia S., Darney, Sally Perreault, de Jager, Christiaan, De Jonge, Christopher J., Drevet, Joel R., Drobnis, Erma Z., Du Plessis, Stefan S., Eisenberg, Michael L., Esteves, Sandro C., Evgeni, Evangelini A., Ferlin, Alberto, Garrido, Nicolas, Giwercman, Aleksander, Goovaerts, Ilse G. F., Haugen, Trine B., Henkel, Ralf, Henningsohn, Lars, Hofmann, Marie-Claude, Hotaling, James M., Jedrzejczak, Piotr, Jouannet, Pierre, Jorgensen, Niels, Brown, Jackson C. Kirkman, Krausz, Csilla, Kurpisz, Maciej, Kvist, Ulrik, Lamb, Dolores J., Levine, Hagai, Loveland, Kate L., McLachlan, Robert, I, Mahran, Ali, Maree, Liana, da Silva, Sarah Martins, Mbizvo, Michael T., Meinhardt, Andreas, Menkveld, Roelof, Mortimer, Sharon T., Moskovtsev, Sergey, Muller, Charles H., Jose Munuce, Maria, Muratori, Monica, Niederberger, Craig, O'Flaherty, Cristian, Oliva, Rafael, OMBELET, Willem, Pacey, Allan A., Palladino, Michael A., Ramasamy, Ranjith, Ramos, Liliana, Rives, Nathalie, Roldan, Eduardo Rs, Rothmann, Susan, Sakkas, Denny, Salonia, Andrea, Cristina Sanchez-Pozo, Maria, Sapiro, Rosanna, Schlatt, Stefan, Schlegel, Peter N., Schuppe, Hans-Christian, Shah, Rupin, Skakkebaek, Niels E., Teerds, Katja, Toskin, Igor, Tournaye, Herman, Turek, Paul J., van der Horst, Gerhard, Vazquez-Levin, Monica, Wang, Christina, Wetzels, Alex, Zeginiadou, Theodosia, and Zini, Armand

Subjects
Reproducitibility, [SDV]Life Sciences [q-bio], andrology, basic semen examination, journal requirements, laboratory training, patient security, quality control, reproducibility, reproductive medicine, science development, standardized laboratory procedures, Humans, Reproducibility of Results, Publishing, Semen, Semen Analysis, Andrology, Obstetrics & Reproductive Medicine, Biology, 11 Medical and Health Sciences, Reproductive Biology, Science & Technology, Rehabilitation, Obstetrics & Gynecology, Obstetrics and Gynecology, Reproductive Medicine, 16 Studies in Human Society, Human and Animal Physiology, Fysiologie van Mens en Dier, Human medicine, Life Sciences & Biomedicine
Abstract

Biomedical science is rapidly developing in terms of more transparency, openness and reproducibility of scientific publications. This is even more important for all studies that are based on results from basic semen examination. Recently two concordant documents have been published: the 6th edition of the WHO Laboratory Manual for the Examination and Processing of Human Semen, and the International Standard ISO 23162:2021. With these tools, we propose that authors should be instructed to follow these laboratory methods in order to publish studies in peer-reviewed journals, preferable by using a checklist as suggested in an Appendix to this article.

Published
2022

Catalog

Books, media, physical & digital resources
See catalog results