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In view of the issues such as opaque data and monitoring blind spots in industrial robots, study was conducted on physical industrial robots, leading to the development of a digital twin robot monitoring system. Firstly, modeling of virtual robots was accomplished from three dimensions: geometric, physical, and logical. Secondly, based on the open platform communications united architecture (OPC UA), data collection and communication for robots were implemented. User display interfaces were designed to achieve real-time visualization of data. Finally, through robot simulation experiments, the relative position errors of the robot end effector in the X, Y, and Z coordinates were determined to be 0.48%, 0.32%, and 0.27%, respectively. The maximum error in joint angles of the robot, verified through synchronized experiments using a digital twin robot monitoring system, was found to be 0.31°. The experimental results demonstrate that the method can achieve motion data monitoring for digital twin industrial robots, reducing the risk of accidents and failures in the production process. It provides insights and directions for the development of intelligent industrial robots. [ABSTRACT FROM AUTHOR]

Objective: Explore the influencing factors of high-risk colorectal adenomas, construct a risk prediction model, and validate it. Methods: A retrospective analysis was conducted on the data of 1408 patients with colorectal adenoma who underwent diagnosis and treatment at the People’s Hospital Affiliated to Jiangsu University from January 2021 to December 2021. They were divided into high-risk colorectal adenoma group (759 cases) and non high-risk colorectal adenoma group (649 cases) based on their pathological characteristics. Use logistic regression analysis to screen independent risk factors for high-risk colorectal adenomas and establish a risk prediction model, and verify the application effectiveness of the prediction model. Results: The results of Logistic regression analysis showed that the location of the lesion was the rectum, hypertension, hyperlipidemia, age≥53 years, and smoking were independent risk factors for high-risk colorectal adenomas (P＜0.05）. Based on the above factors, a column chart model was established to predict the risk of high-risk colorectal adenomas. The Hosmer-Lemeshow test and receiver operating characteristic curve (ROC) analysis showed that the risk prediction model had good fit and predictive performance, and could be used for risk prediction of high-risk adenomas. Conclusion: The location of the lesion is the rectum, hypertension, hyperlipidemia, age ≥53 years, and smoking are independent risk factors for high-risk colorectal adenomas. Clinicians can provide early preventive intervention for high-risk patients to slow down the occurrence of high-risk adenomas. [ABSTRACT FROM AUTHOR]

The primary structure formation criterion based on the particle packing theory was applied to the gradation design of fine-grained porous asphalt mixture, optimized the content of the range of the primary structure further within the grade range required by specification in order to enhance the skeleton strength of and improve the high-temperature performance of fine-grained porous asphalt mixture, laboratory tests and theoretical analysis research methods were combined to verify the applicability of this criterion to enhance the aggregate strength by the skeleton penetration test, and determined the influence of the skeleton strength of aggregates on the high-temperature performance by the modified uniaxial compression creep test. The research results show that applying the primary structure formation criterion to the gradation design can improve the skeleton strength and the high-temperature performance of fine-grained porous asphalt mixture, and there is a obvious correlation between the two aspects, the larger the skeleton strength, the better the high-temperature performance. [ABSTRACT FROM AUTHOR]

With the popularity of snack food, the consumption of fried potato products is increasing. French fries and potato chips are loved by young and old consumers with its crunchy and delicious properties, diverse tastes and easy to eat characteristics. The main flavor substances in French fries include pyrazines, 2,4-decanodienal, 2-decenoaldehyde, 2-methylbutanal, 3-methylbutanal, 4- hydroxy- 2,5- dimethylfuranone, methylpropanol and methanethiol, etc. The main flavor substances in potato chips include methylthio-propanaldehyde, 2,4-decanodienal, 2-ethyl-3,6-dimethylpyrazine, 2, 6-diethylpyrazine, 2-octenal and 2-phenylacetaldehyde, etc. The most important flavor compounds are pyrazines, which have strong pleasant smells of fresh potatoes, baked potatoes and potato earth taste. The key components are 2-ethyl-3, 5-dimethylpyrazine, 3- ethyl- 2,5- dimethylpyrazine, 2,3- diethyl- 5- methylpyrazine, 2- ethyl- 3,6- dimethylpyrazine, 2,6-diethylpyrazine, 3- isobutyl- 2- methoxypyrazine and so on. The review summarized the type of flavor substances in French fries and potato chips, non-enzymatic browning reaction and the influence of fried time, temperature and light on the flavor, respectively. Meanwhile, the factors affecting the flavor of fried potato during production, processing and storage were also discussed. Especially, the content and trend of the key substances determining the flavor of fried potato were analyzed. This review work would play a guiding role in the research and development of potato French fries and chips related industries. [ABSTRACT FROM AUTHOR]

Ischemia-reperfusion injury (IRI) is a pathophysiological process, which widely exists in organ transplantation and surgery. IRI is mainly manifested with hypoxia injury of organs or tissues during the ischemia period, which could be further aggravated after reperfusion. Ischemia-reperfusion induces tissue cell injury, releases damage-associated molecular pattern and further activates multiple immune cells via pattern recognition receptor, leading to aseptic inflammation and aggravating tissue injury. Cyclic guanosine monophosphate-adenosine monophosphate synthase (cGAS), as a critical member of pattern recognition receptor, could activate the stimulator of interferon genes (STING) signal pathway and play an important regulatory role in innate immune response. At present, increasing evidences have shown that cGAS-STING signal pathway plays a significant role in organ IRI. In this article, STING signaling pathway, its role and mechanism in IRI of different organs were reviewed, aiming to provide novel ideas for clinical interventions. [ABSTRACT FROM AUTHOR]

The acoustic liner of the nacelle of an aeroengine is the most important noise reduction device of the engine. In order to establish an accurate impedance model related to the structure and acoustic performance of the acoustic liner, it is necessary to analyze the acoustic impedance eduction technology of the liner. Two liner impedance eduction techniques, in-situ impedance eduction method and straightforward method, were compared and analyzed. Same flow tube acoustic test platform, liners with controllable deviation, and repeatability test of impedance measurement were used to ensure the subjectivity of the comparison. Two aforementioned impedance eduction methods were used to obtain the acoustic impedance of both single-degree-of-freedom acoustic liner and double-freedom liner. It indicated that the measurement results from the two impedance eduction methods were well matched with each other in frequency of both mid-range and high-range, and there were significant differences in the low-frequency ranges. Compared with the straightforward method, the in-situ method was more applicable for a wider range of frequency, and it could also identify the local acoustic impedance characteristics of the acoustic liner. In-situ method was less limited for the size of acoustic liners, however, the breaking of the liner structure was inevitable for such method, which means such method was more suitable for traditional liners. The straightforward method could measure the overall impedance characteristics of the acoustic liner. It could also obtain accurate impedance results in both middle and high frequency range without breaking liner structures, and therefore it could be used in a wider range of plate-type sound-absorbing materials. [ABSTRACT FROM AUTHOR]

[Purpose/Significance] With the deepening of digital humanistic research on ancient books, the requirement for fine-grained classification based on text content is increasing continuously, and reasonable classification has become the key to the research and effective utilization of digital ancient books.[Method/Process] The research uses the concept of faceted classification, takes the text data of ancient books and related dictionary of ancient books as the research object, and combines conceptual semantic information to organize and describe the features of the content of ancient books. [Results/Conclusions] The classification system constructed in this paper breaks through the limitation of the number, genre and type of ancient books. The research selects five dimensions of politics, economy, culture, society and military to organize and reveal the contents of ancient books in an orderly manner, which is of great value to the in-depth development and utilization of digital resources of ancient books. [ABSTRACT FROM AUTHOR]

Because the actuator composed of the dielectric elastomer has a viscoelastic effect during the driving process of the soft robot, which makes it difficult to accurately control the robot, a kind of beetle antennae search (BAS) algorithm optimization PID was proposed. The control algorithm was used for precise control of the soft robot. Firstly, the rheological model was used to build the dynamic model of the dielectric elastomer actuator (DEA). Secondly, the use of the BAS algorithm had a strong global optimization ability and a single optimization strategy to convert the PID controller parameters into BAS algorithm in the three-dimensional space. Finally, the PID parameters in the iterative process were optimized. The experimental results show that the maximum tracking error of sine triangle wave is 0.95 mm and 1.08 mm. Compared with other control methods the proposed method has better control accuracy of the actuator. [ABSTRACT FROM AUTHOR]

A new type of integrated bathymetry device has been developed to better solve the problem of difficult bathymetry in the areas restricted to ship movement, such as the quay front and below, shallow water areas, etc., this paper has developed. The device adopts an integrated design, integrating power module, bathymetry module, hydrological parameter measurement module and professional bathymetry software. Taking the measurement data of traditional single-beam sounder as reference, we analyzed and evaluated the measurement data of the integrated bathymetric device in terms of draught depth, sound speed, internal compliance and external compliance. The results proved that the integrated bathymetric device has good measurement accuracy and performance stability, and can obtain high-precision bathymetric data in real-time and efficiently in the areas restricted to ship movement, such as the quay front and below, shallow water areas. [ABSTRACT FROM AUTHOR]

Objective To evaluate the effect of irregular follow-up during normalized prevention and control of novel coronavirus pneumonia (COVID-19) epidemic on BK virus (BKV) reactivation and clinical prognosis of kidney transplant recipients. Methods Clinical data of 363 kidney transplant recipients were retrospectively analyzed, and they were divided into the pre-epidemic follow-up group and during-epidemic follow-up group according to the follow-up time. All patients were followed up for 1 year. The follow-up interval was compared between two groups. The infection of BKV and the correlation between the infection process of BKV and renal graft function were analyzed in two groups. Results A total of 1 790 preson-times were followed up before COVID-19 epidemic and 2680 during COVID-19 epidemic. Compared with the during-epidemic follow-up group, the follow-up intervals within 3, 3-6 and 7-12 months after kidney transplantation were shorter in the pre-epidemic follow-up group, and the differences were statistically significant (all P<0.05). Within 1 year after kidney transplantation, 35 cases (32%) were diagnosed with BKV viruria, 3 cases (3%) of BKV viremia and 1 case (1%) of BKV-associated nephropathy (BKVAN) in the pre-epidemic follow-up group, and 53 (25%), 3 (1%) and 1 (1%) in the during-epidemic follow-up group, with no statistical significance (all P>0.05). In the pre-epidemic follow-up group, the time for the initial diagnosis of BKV viruria was longer and the viral load of the first urinary BKV reactivation was smaller than those in the during-epidemic follow-up group, with statistical significance (both P<0.05). The load of the first urinary BKV reactivation was positively correlated with the peak load of urinary BKV, and the differences between the baseline and serum creatinine levels at 1 and 3 months after BKV reactivation (all P<0.05). Conclusions Irregular follow-up after kidney transplantation may lead to early BKV reactivation and higher detection value of the first viral load of urinary BKV, delay diagnosis and interventions, and lead to poor prognosis. It is urgent to establish a remote follow-up system to meet the follow-up requirements of kidney transplant recipients when public health incidents occur. [ABSTRACT FROM AUTHOR]

Objective To analyze the influencing factors in detection of sperm mitochondrial membrane potential（MMP） by flow cytometry. Methods After reproducibility analysis of sperm MMP using flow cytometry, semen samples that met the requirements of MMP detection were randomly collected, The effects of sample standing time, temperature, sample preservation solution, freezing and other factors on the results of MMP were analyzed. Results The semen samples with high,medium and low MMP levels were repeatedly tested by flow cytometry for 10 times, and the CV of the results was all less than 7%. With the extension of the sample storage time at room temperature, the level of sperm MMP was gradually decreased.Compared with the result of the placed sample for 30 min（43.31±13.96）, the level of sperm MMP was significantly decreased in the placed sample for 2 hours（35.44±17.23）. The decrease of MMP of semen samples stored at 2-8 ℃ was less than that of samples stored at room temperature, but there was no significant difference（P>0.05）. The level of sperm MMP in the samples with self-made sample protective solution store at 2-8 ℃ was significantly higher than that of the samples without protective agent（P<0.05）, and the decline rate of MMP level was significantly slower（P<0.05）. The temperature of semen stored at 2-8 ℃was less than that of samples stored at room temperature, but there was no statistical difference. Semen samples with cryoprotectant at 1:1 were frozen at-20 ℃, which caused a significant damage of sperm MMP（P<0.01）. Conclusion For sperm MMP detection using FCM, the sample standing time has a great influence on the test result. It is recommended to finish the test within half an hour after semen liquefaction. In order to improve the quality control and working efficiency of the laboratory, the samples is suggested to be refrigerated in the sample preservation solution and the testing can be completed within 2 hours. Frozen semen samples can not be used as internal quality control for sperm MMP detection. [ABSTRACT FROM AUTHOR]

To give full play to the production potential of Xiangyan 7 and to optimize the supporting planting technology, the effects of 9 differ- ent field structures on the yield and quality of Xiangyan 7 were studied by split plot design. The research results showed that the two field struc- tures were 21 leaves left after topping and 4 leaves removed at the bottom, and 22 leaves left after topping and 5 leaves removed at the bottom. These two field structures were most favorable for Xiangyan 7 to obtain higher yield and better quality of tobacco leaves. [ABSTRACT FROM AUTHOR]

In order to improve the feasibility and comprehensiveness of the application of BIM lightweight technology in water conservancy projects, this paper analyzed and summarized the mainstream BIM lightweight technology. Taking Miyun reservoir reconstruction and elimination of hazards project as an example, it put forward the application route of water conservancy project BIM lightweight technology, and improved the application effects of BIM lightweight technology in different construction stages. In the design stage, the comprehensive use of model reduction optimization, rendering optimization and BIM lightweight collaborative design platform can greatly improve the efficiency of three-dimensional model design; By using the BIM lightweight engine to transmit the BIM design model to the construction stage and establishing a BIM lightweight construction management platform, the quality of construction management can be effectively improved, ensuring that the project is completed on time and with quality. For the current status of BIM lightweight technology, this paper puts forward suggestions for future development: BIM lightweight technology should be able to integrate a variety of water conservancy engineering industry characteristics of data, improve the BIM specifications and standards, so that the BIM lightweight application system is more standardized and scientific. [ABSTRACT FROM AUTHOR]

Objective To investigate the feasibility and clinical experience of kidney transplantation from donors with Marfan syndrome (MFS). Methods Clinical data of 2 recipients undergoing kidney transplantation from the same MFS patient were retrospectively analyzed and literature review of 2 cases was conducted. Characteristics and clinical diagnosis and treatment of kidney transplantation from MFS patients were summarized. Results The Remuzzi scores of the left and right donor kidneys of the MFS patient during time-zero biopsy were 1 and 2. No significant difference was observed in the renal arteriole wall compared with other donors of brain death and cardiac death. Two recipients who received kidney transplantation from the MFS patient suffered from postoperative delayed graft function. After short-term hemodialysis, the graft function of the recipients received the left and right kidney began to gradually recover at postoperative 10 d and 20 d. After discharge, serum creatinine level of the recipient received the left kidney was ranged from 80 to 90 μmol/L, whereas that of the recipient received the right kidney kept declining, and the lowest serum creatinine level was 232 μmol/L before the submission date (at postoperative 43 d). Through literature review, two cases successfully undergoing kidney transplantation from the same MFS donor were reported. Both two recipients experienced delayed graft function, and then renal function was restored to normal. Until the publication date, 1 recipient has survived for 6 years, and the other recipient died of de novo cerebrovascular disease at postoperative 2 years. Conclusions MFS patients may serve as an acceptable source of kidney donors. However, the willingness and general conditions of the recipients should be carefully evaluated before kidney transplantation. Intraoperatively, potential risk of tear of renal arterial media should be properly treated. Extensive attention should be paid to the incidence of postoperative complications. [ABSTRACT FROM AUTHOR]

Objective This study aimed to explore the predictive value of endoplasmic reticulum stress response （ERS）-related regulatory gene expression for the pathological grading, prognosis, and malignant progression phenotype of gliomas （excluding glioblastomas）. Methods After excluding duplicate and non-survival samples, clinical sequencing data of glioma samples from the American Cancer Genome Atlas and the Chinese Brain Glioma Genome Atlas were selected as the training and validation sets. A prognosis-related ERS risk regression model was constructed through differential gene enrichment and protein interaction analysis. The predictive value of ERS Cox model for glioma prognosis and malignant progression phenotype was validated using ROC curve analysis, real-time fluorescence quantitative PCR, and immunohistochemistry. Results The study findings reveal that the expression of 7 ERS-related risk factors increases with the rise in glioma grade and accurately predicts unfavorable patient prognosis （with accuracies higher than 0.7 for predictions at 1, 3, and 5 years）, all of which are statistically significant. Further validation demonstrates a positive correlation between ERS risk genes and the glioma malignant phenotype marker CD44, as well as a negative correlation with the clinically favorable prognosis marker GPR158, both of which have statistical differences （P < 0.05）. Finally, gene expression and immunohistochemistry analysis of clinical samples confirm that ERS-related risk factors are highly expressed in higher-grade gliomas, positively correlated with CD44 expression, with statistical significance （P < 0.05）.Conclusion The preliminary results of the study suggest that the risk regression model based on ERS response exhibits the capacity to predict pathological grading and prognosis. Moreover, it demonstrates a positive correlation with the malignant progression phenotype of gliomas. These findings offer insights for precise and targeted diagnosis and treatment of gliomas. [ABSTRACT FROM AUTHOR]

Objective To summarize the cases of hematoma in remote site after infratentorial craniotomy for tumors, and to explore the early identification methods as well as prevention and treatment strategies. Methods The clinical data of patients who underwent infratentorial craniotomy for tumors from Dec 2019 to Nov 2021 in the skull base subspecialty group of the department of neurosurgery, Huashan Hospital, Fudan University were retrospectively analyzed to summarize the location and type of hematoma in remote sites and its causes，and to explore its early identification methods and prevention strategies. Results Among the 490 patients who underwent infratentorial craniotomy for tumors，18 patients （3.67%） developed hematoma in remote site, including 9 cases with supratentorial subdural hematoma，3 cases with occipital epidural hematoma，2 cases with supratentorial subdural hematoma combined with interhemispheric subdural hematoma，2 cases with intraventricular hematoma，1 cases with interhemispheric subdural hematoma, and 1 patient temporal lobe intracerebral hematoma combined with subarachnoid hemorrhage. Two cases were accurately identified during operation, and the operation was terminated. Intraoperative head CT was performed to determine the type of hematoma, and surgical treatment was performed. All the other 16 cases were identified in the early postoperative period, and head CT was performed to identify the type of hematoma. One patient was treated with surgery and 15 cases were treated conservatively. All the 18 cases were followed up for 2-21 months after operation, and there was no death case. Conclusion The hematoma in remote site after infratentorial craniotomy for tumors is a rare and serious threat to the safety of surgery, mostly manifested as supratentorial subdural hematoma, epidural hematoma, intraventricular hematoma, interhemispheric subdural hematoma and intracerebral hematoma, which can be associated with subarachnoid hemorrhage. Perioperative active prevention, early and accurate identification as well as timely and effective treatment can significantly improve the prognosis of patients. [ABSTRACT FROM AUTHOR]

To investigate the therapeutic effect of rhubarb decoction (RD） retention enema on a rat model of minimal hepatic encephalopathy (MHE） and its mechanism of action based on bile acid (BA） metabolomics. Methods A total of 55 male Sprague－Dawley rats were randomly divided into blank group (NC group with 10 rats), hepatic encephalopathy group (HE group with 15 rats), MHE group with 15 rats, and MHE+rhubarb decoction treatment group (MHEY group with 15 rats）. Intraperitoneal injection of carbon tetrachloride (CCl4 ） and thioacetamide (TAA） was performed to establish a rat model of MHE or HE, and the rats were sacrificed after 2 weeks of administration. The serum levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), total bilirubin (TBil), and total bile acid (TBA） and the concentration of blood ammonia were measured; the colonic contents were collected to measure pH value; liver and brain tissue samples were collected, and HE staining was used to observe the histopathological changes of the liver; the bile was collected, and liquid chromatography－mass spectrometry was used to perform BA－targeted metabolomics analysis. Continuous data were expressed as mean±standard deviation; a one－way analysis of variance was used for comparison between multiple groups, and the least significant difference t－test was used for further comparison between two groups. Results Compared with the NC group, the HE group and the MHE group had a significant increase in searching platform latency (after modelling and after administration） and a significant reduction in the number of platform crossings (all P<0.05); compared with the MHE group, the MHEY group had a significant reduction in searching platform latency (after administration） and a significant increase in the number of platform crossings, and the HE group had a significant increase in searching platform latency and a significant reduction in the number of platform crossings (all P<0.05）. Compared with the NC group, the HE group and the MHE group had significant increases in AST, ALT, ALP, TBil, TBA, blood ammonia, and colon pH value (all P<0.05); compared with the MHE group, the MHEY group had significant reductions in AST, ALT, ALP, TBil, TBA, blood ammonia, and colon pH value (all P<0.05), and the HE group had significant increases in AST, ALT, ALP, TBil, TBA, blood ammonia, and colon pH value (all P<0.05）. The MHE group had significantly lower TBA, primary BA, and secondary BA than the NC group (all P<0.05); compared with the MHE group, the HE group had significantly lower TBA and primary BA (all P< 0.05), and the MHEY group had significantly higher TBA and primary BA (all P<0.05）. Compared with the NC group, the MHE group had significant reductions in GCDCA, GUDCA, GHDCA, TCDCA, TUDCA, GLCA, and TLCA (all P<0.05） and significant increases in γ－MCA, THCA, 7－KDCA, AlloLCA, and α－MCA (all P<0.05), and compared with the MHE group, the MHEY group had significant increases in THDCA, TMCA, TCDCA, TUDCA, and TLCA (all P<0.05）. Conclusion RD retention enema can improve liver injury and cognitive function in a rat model of MHE induced by CCl4 and TAA by regulating the enterohepatic circulation of BA, possibly by increasing the synthesis of taurine－binding BA. [ABSTRACT FROM AUTHOR]

为了解决传统卫星定位法在山区狭窄河道水下地形测量中作业半径小、工作效率低、定位精度差等问题，基于 GNSS-PPK 技术开展了山区河道型水库的水下地形测量工作研究，简要介绍了 GNSS-PPK 技术原理，重点论述了 GNSS-PPK 技术特点及在山 区河道型水库水下地形测量条件下应用的优势，并分析了影响水下地形测量成果质量的诸多因素以及具体的解决方案。 在四川省 乐山市沙湾水库实测验证结果表明，GNSS-PPK 技术在增大测量作业半径的同时，定位精度能够达到厘米级，并且定位结果稳定可 靠，能够满足一般大比例尺水下地形图测量要求。 [ABSTRACT FROM AUTHOR]

为了解决传统卫星定位法在山区狭窄河道水下地形测量中作业半径小、工作效率低、定位精度差等问题，基于GNSS-PPK 技术开展了山区河道型水库的水下地形测量工作研究，简要介绍了GNSS-PPK 技术原理，重点论述了GNSS-PPK 技术特点及在山 区河道型水库水下地形测量条件下应用的优势，并分析了影响水下地形测量成果质量的诸多因素以及具体的解决方案。在四川省 乐山市沙湾水库实测验证结果表明，GNSS-PPK 技术在增大测量作业半径的同时，定位精度能够达到厘米级，并且定位结果稳定可 靠，能够满足一般大比例尺水下地形图测量要求。 [ABSTRACT FROM AUTHOR]

目的　探讨血清网膜素 1（Omentin-1)、B 细胞淋巴瘤/白血病 2（Bcl-2)、分化簇 163（CD163）水平与高血压 脑出血（HICH）患者病情程度和预后的关系。方法　选择 HICH 患者 106 例（观察组），根据美国国立卫生研究院卒 中量表（NIHSS）评分评估病情程度，病情程度轻度 24 例、中度 45 例、重度 37 例；出院 30天门诊复查，根据格拉斯哥 预后量表评分评估预后，预后不良 44 例、预后良好 62 例。同期另选体检健康的志愿者50例作为对照组。采集所有 研究对象外周静脉血，离心留取血清，采用 ELISA 法检测血清 Omentin-1、Bcl-2、CD163。比较两组血清 Omentin-1、 Bcl-2、CD163 水平以及不同病情程度 HICH 患者血清 Omentin-1、Bcl-2、CD163 水平。采用Spearman 相关分析法分析 HICH 患者血清 Omentin-1、Bcl-2、CD163 水平与 NIHSS 评分的关系。采用受试者工作特征（ROC）曲线分析血清 Omentin-1、Bcl-2、CD163 水平对 HICH 患者预后不良的预测价值。结果　观察组血清 Omentin-1 水平显著低于对照 组，血清 Bcl-2、CD163 水平显著高于对照组（P 均<0. 01)。随着病情程度加重，HICH 患者血清 Omentin-1 水平逐渐降 低，血清 Bcl-2、CD163 水平逐渐升高（P 均<0. 01)。Spearman 相关分析显示，HICH 患者血清 Omentin-1 水平与 NIHSS 评分呈负相关关系，血清 Bcl-2、CD163 水平与 NIHSS 评分呈正相关关系（r 分别为-0. 691、0. 788、0. 703，P 均<0. 01)。 ROC 曲线分析显示，血清 Omentin-1、Bcl-2、CD163 水平单独和联合预测 HICH 患者预后不良的曲线下面积分别为 0. 780、0. 781、0. 784、0. 942，血清 Omentin-1、Bcl-2、CD163 水平联合预测 HICH 患者预后不良的曲线下面积显著高 于三者单独（Z 分别为3. 777、3. 898、3. 695，P 均<0. 01)。结论　HICH 患者血清 Omentin-1水平降低，血清 Bcl-2、 CD163 水平升高，其水平变化与病情程度和预后密切相关。 [ABSTRACT FROM AUTHOR]

In order to study the aerodynamic noise of UAV (unmanned aerial vehicle)propeller at ground takeoff conditions, a propeller aerodynamic noise test platform was developed. The propeller aerodynamic noise test was carried out in a semi anechoic room, and the aerodynamic performance and far-field noise characteristics were obtained. The variation of aerodynamic parameters such as tension and torque and the directivity of far-field noise with propeller speed and blade angle were analyzed. The results show that the aerodynamic parameters such as tension and torque increase with the increase of rotating speed and blade angle. The region with largest far-field nosie varies with the propeller speed and blade angle. The test platform and test scheme could be used as a means to valuate the effect of propeller aerodynamic noise design. [ABSTRACT FROM AUTHOR]

The North Branch is one of the important branch channels of the Yangtze River Estuary. Owing to the closely relationship with smooth navigation, ecological protection and estuary project safety, watercourse evolution of North Branch has received widespread attention in the field of hydraulics and oceanography. Based on the cross-sectional data between 2007 and 2017 and GIS technology, we analyzed the evolution characteristics and influencing factors in the North Branch. The results show that: (1) During 2007 to 2017, erosion was the domain phenomenon in the North Branch of Yangtze River Estuary, with a net erosion of ~13.97×106 t and an erosion rate of 0.46 cm/a. Net erosion occurred in the upper and middle reaches, while net siltation occurred in the lower reaches. (2) The reduction of sediment transport and a huge amount of tidal flat reclamations, played main driving factors for the erosion in the North Branch, as the same as the disappearance of tidal sand ridges. Changes of channel width and curvature are the main reasons for the spatial difference of erosion and deposition in the North Branch. The geostrophic force had an obviously influence on the evolution in the North Branch. (3) In light of the above findings, we suggested strengthen the coordinated development of regional economy, society and ecological environment in the future, to protect the tidal flats and wetlands in the North Branch. [ABSTRACT FROM AUTHOR]

In order to obtain the fatigue life of aeroengine turbine rotor blades, orthogonal load decoupling combined loading was realized by electromagnetic induction heating and high-low cycle composite load coordinated loading control method. The coupling responses of rotor blades under high temperature environment, low cycle centrifugal load and high cycle vibration load were studied, and the above technology were verified based on turbine blade simulation test pieces. The results show that the test technology is feasible and correct. It can be seen that this technology can realize multi field coupling complex load strength test loading of aeroengine structural components. [ABSTRACT FROM AUTHOR]

Objective　To assess the correlation between neutrophil-lymphocyte ratio （NLR） and the disease activity of systemic lupus erythematosus （SLE）. Methods　A total of 536 patients with SLE from the Department of Rheumatology and Immunology of the First Affiliated Hospital of Kunming Medical University were selected. According to the SLE Disease Activity Index （SLEDAI） score，patients with SLE were divided into inactive group，lightly active group，moderately active group，and severely active group. The differences in NLR among the four groups were compared，and the correlation between NLR and SLEDAI score was analyzed through Spearman correlation analysis. Results　There were differences in NLR levels among the four groups. The results of pairwise comparison showed that the NLR level of the moderately active group was higher than that of the inactive group （adjusted P < 0.001）；the NLR level of the severely active group was higher than that of the inactive group （adjusted P < 0.001）；the NLR level of the severely active group was higher than that of the lightly active group （ P = 0.011 after adjustment）. The NLR of SLE patients were positively correlated with SLEDAI scores （ P < 0.05. Conclusion　NLR can be used as a reference index to evaluate the disease activity of SLE patients. [ABSTRACT FROM AUTHOR]

Over the past 20 years, the area bone mineral density (aBMD) has played an important role in the clinical and scientific research of osteoporosis (OP). However, the incompletely standardization of bone mineral content (BMC) and its inadaptability to the principle in bone biomechanics lead to the increasely rate of misdiagnosis or missed diagnosis. Therefore, volumetric bone mineral density (vBMD) which is a better index of bone biomechanics, has been put forward. vBMD is a morphological index to bone biomechanics, which may be a transitional index to obtain bone strength in vivo. In addition, vBMD can exclude the influence of different bone size on bone mass and enhance the comparability between individuals. In clinical application, vBMD widens the application range of normal reference value (shared by children and adults), and improves the accuracy of OP diagnosis. vBMD has many advantages, and it is worth further developing. [ABSTRACT FROM AUTHOR]

Objective To evaluate the association between neutrophil-lymphocyte ratio （NLR） and renal damage in patients with systemic lupus erythematosus （SLE）. Methods A total of 410 patients with SLE from the Department of Rheumatology and Immunology of the First Affiliated Hospital of Kunming Medical University were selected. According to whether accompanied by renal involvement, patients with SLE were divided into non-lupus nephritis group （non-LN group） and lupus nephritis group （LN group）. The differences in NLR between the two groups were compared, and the correlation between NLR and renal damage was analyzed. Results The NLR of LN group was significantly higher than that of SLE patients in non-LN group, and the difference wsa statistically significant （P < 0.05）. The NLR of SLE patients were positively correlated with leukocyte count, neutrophils count, serum creatinine, blood urea nitrogen, ESR, CRP, PCT and 24-hour urine protein, and negatively correlated with lymphocyte count, total protein, albumin and globulin, respectively. Conclusion NLR can be used as an auxiliary index to evaluate renal damage in SLE patients. [ABSTRACT FROM AUTHOR]